DK3142642T3 - LIPOSOMAL MUPIROCIN - Google Patents
LIPOSOMAL MUPIROCIN Download PDFInfo
- Publication number
- DK3142642T3 DK3142642T3 DK15722359.5T DK15722359T DK3142642T3 DK 3142642 T3 DK3142642 T3 DK 3142642T3 DK 15722359 T DK15722359 T DK 15722359T DK 3142642 T3 DK3142642 T3 DK 3142642T3
- Authority
- DK
- Denmark
- Prior art keywords
- liposomes
- mupirocin
- hpcd
- examples
- loading
- Prior art date
Links
- 229960003128 mupirocin Drugs 0.000 title claims description 171
- MINDHVHHQZYEEK-UHFFFAOYSA-N (E)-(2S,3R,4R,5S)-5-[(2S,3S,4S,5S)-2,3-epoxy-5-hydroxy-4-methylhexyl]tetrahydro-3,4-dihydroxy-(beta)-methyl-2H-pyran-2-crotonic acid ester with 9-hydroxynonanoic acid Natural products CC(O)C(C)C1OC1CC1C(O)C(O)C(CC(C)=CC(=O)OCCCCCCCCC(O)=O)OC1 MINDHVHHQZYEEK-UHFFFAOYSA-N 0.000 title claims description 169
- 229930187697 mupirocin Natural products 0.000 title claims description 169
- MINDHVHHQZYEEK-HBBNESRFSA-N mupirocin Chemical compound C[C@H](O)[C@H](C)[C@@H]1O[C@H]1C[C@@H]1[C@@H](O)[C@@H](O)[C@H](C\C(C)=C\C(=O)OCCCCCCCCC(O)=O)OC1 MINDHVHHQZYEEK-HBBNESRFSA-N 0.000 title claims description 6
- 239000002502 liposome Substances 0.000 claims description 277
- DDHVILIIHBIMQU-YJGQQKNPSA-L mupirocin calcium hydrate Chemical compound O.O.[Ca+2].C[C@H](O)[C@H](C)[C@@H]1O[C@H]1C[C@@H]1[C@@H](O)[C@@H](O)[C@H](C\C(C)=C\C(=O)OCCCCCCCCC([O-])=O)OC1.C[C@H](O)[C@H](C)[C@@H]1O[C@H]1C[C@@H]1[C@@H](O)[C@@H](O)[C@H](C\C(C)=C\C(=O)OCCCCCCCCC([O-])=O)OC1 DDHVILIIHBIMQU-YJGQQKNPSA-L 0.000 claims description 174
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Landscapes
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461977731P | 2014-04-10 | 2014-04-10 | |
| PCT/IL2015/050376 WO2015155773A1 (en) | 2014-04-10 | 2015-04-08 | Liposomal mupirocin |
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| Publication Number | Publication Date |
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| DK3142642T3 true DK3142642T3 (en) | 2018-12-17 |
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| Application Number | Title | Priority Date | Filing Date |
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| DK15722359.5T DK3142642T3 (en) | 2014-04-10 | 2015-04-08 | LIPOSOMAL MUPIROCIN |
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| Country | Link |
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| US (1) | US10004688B2 (enExample) |
| EP (1) | EP3142642B1 (enExample) |
| JP (1) | JP6676035B2 (enExample) |
| CN (1) | CN106659795B (enExample) |
| DK (1) | DK3142642T3 (enExample) |
| WO (1) | WO2015155773A1 (enExample) |
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| TWI754659B (zh) * | 2016-08-08 | 2022-02-11 | 台灣微脂體股份有限公司 | 用於製備含有弱酸性劑之微脂體組合物的傳輸載體、方法及套組 |
| EP3520819A1 (en) * | 2018-01-31 | 2019-08-07 | Universität Basel | Shear stress sensitive liposomes |
| CN114727960A (zh) * | 2019-10-03 | 2022-07-08 | 耶路撒冷希伯来大学伊森姆研究发展有限公司 | 数个脂质体大麻素及其用途 |
| EP4125809A1 (en) * | 2020-03-25 | 2023-02-08 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd | Liposomal formulations comprising at1 receptor blockers and uses thereof |
| CN116270433B (zh) * | 2023-03-14 | 2023-09-01 | 郑州大学第一附属医院 | 一种莫匹罗星软膏、制备方法及用途 |
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| WO1995015746A1 (en) * | 1993-12-10 | 1995-06-15 | The School Of Pharmacy | Liposome delivery systems |
| EP0825852B1 (en) * | 1995-04-18 | 2004-07-07 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Liposome drug-loading method and composition |
| CA2584583A1 (en) * | 2004-10-28 | 2006-05-11 | Alza Corporation | Lyophilized liposome formulations and method |
| WO2007005754A2 (en) | 2005-07-01 | 2007-01-11 | Alza Corporation | Liposomal delivery vehicle for hydrophobic drugs |
| WO2007044745A1 (en) * | 2005-10-11 | 2007-04-19 | Biosynexus Incorporated | Lantibiotic and mupirocin compositions for treating bacterial infections |
| US20090196918A1 (en) * | 2008-02-01 | 2009-08-06 | University Of Kentucky Research Foundation | Liposomal formulations of hydrophobic lactone drugs in the presence of metal ions |
| JP5785175B2 (ja) * | 2009-10-26 | 2015-09-24 | 石葯集団中奇制葯技▲術▼（石家庄）有限公司 | スルホブチルエーテルシクロデキストリン塩を含有する内水相を有するリポソーム |
| US20130337051A1 (en) * | 2011-03-01 | 2013-12-19 | To-Bbb Holding B.V. | Advanced active liposomal loading of poorly water-soluble substances |
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- 2015-04-08 CN CN201580019117.7A patent/CN106659795B/zh active Active
- 2015-04-08 JP JP2017504294A patent/JP6676035B2/ja active Active
- 2015-04-08 US US15/303,131 patent/US10004688B2/en active Active
- 2015-04-08 DK DK15722359.5T patent/DK3142642T3/en active
Also Published As
| Publication number | Publication date |
|---|---|
| JP6676035B2 (ja) | 2020-04-08 |
| CN106659795A (zh) | 2017-05-10 |
| US20170027869A1 (en) | 2017-02-02 |
| US10004688B2 (en) | 2018-06-26 |
| EP3142642B1 (en) | 2018-08-29 |
| CN106659795B (zh) | 2023-06-02 |
| WO2015155773A1 (en) | 2015-10-15 |
| JP2017513938A (ja) | 2017-06-01 |
| EP3142642A1 (en) | 2017-03-22 |
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