DK3142642T3 - LIPOSOMAL MUPIROCIN - Google Patents
LIPOSOMAL MUPIROCIN Download PDFInfo
- Publication number
- DK3142642T3 DK3142642T3 DK15722359.5T DK15722359T DK3142642T3 DK 3142642 T3 DK3142642 T3 DK 3142642T3 DK 15722359 T DK15722359 T DK 15722359T DK 3142642 T3 DK3142642 T3 DK 3142642T3
- Authority
- DK
- Denmark
- Prior art keywords
- liposomes
- mupirocin
- hpcd
- examples
- loading
- Prior art date
Links
- 229960003128 mupirocin Drugs 0.000 title claims description 171
- MINDHVHHQZYEEK-UHFFFAOYSA-N (E)-(2S,3R,4R,5S)-5-[(2S,3S,4S,5S)-2,3-epoxy-5-hydroxy-4-methylhexyl]tetrahydro-3,4-dihydroxy-(beta)-methyl-2H-pyran-2-crotonic acid ester with 9-hydroxynonanoic acid Natural products CC(O)C(C)C1OC1CC1C(O)C(O)C(CC(C)=CC(=O)OCCCCCCCCC(O)=O)OC1 MINDHVHHQZYEEK-UHFFFAOYSA-N 0.000 title claims description 169
- 229930187697 mupirocin Natural products 0.000 title claims description 169
- MINDHVHHQZYEEK-HBBNESRFSA-N mupirocin Chemical compound C[C@H](O)[C@H](C)[C@@H]1O[C@H]1C[C@@H]1[C@@H](O)[C@@H](O)[C@H](C\C(C)=C\C(=O)OCCCCCCCCC(O)=O)OC1 MINDHVHHQZYEEK-HBBNESRFSA-N 0.000 title claims description 6
- 239000002502 liposome Substances 0.000 claims description 277
- DDHVILIIHBIMQU-YJGQQKNPSA-L mupirocin calcium hydrate Chemical compound O.O.[Ca+2].C[C@H](O)[C@H](C)[C@@H]1O[C@H]1C[C@@H]1[C@@H](O)[C@@H](O)[C@H](C\C(C)=C\C(=O)OCCCCCCCCC([O-])=O)OC1.C[C@H](O)[C@H](C)[C@@H]1O[C@H]1C[C@@H]1[C@@H](O)[C@@H](O)[C@H](C\C(C)=C\C(=O)OCCCCCCCCC([O-])=O)OC1 DDHVILIIHBIMQU-YJGQQKNPSA-L 0.000 claims description 174
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Landscapes
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| US201461977731P | 2014-04-10 | 2014-04-10 | |
| PCT/IL2015/050376 WO2015155773A1 (en) | 2014-04-10 | 2015-04-08 | Liposomal mupirocin |
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| DK3142642T3 true DK3142642T3 (en) | 2018-12-17 |
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| EP3520819A1 (en) | 2018-01-31 | 2019-08-07 | Universität Basel | Shear stress sensitive liposomes |
| US20220347096A1 (en) * | 2019-10-03 | 2022-11-03 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd | Liposomal cannabinoids and uses thereof |
| EP4125809A1 (en) * | 2020-03-25 | 2023-02-08 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd | Liposomal formulations comprising at1 receptor blockers and uses thereof |
| CN116270433B (zh) * | 2023-03-14 | 2023-09-01 | 郑州大学第一附属医院 | 一种莫匹罗星软膏、制备方法及用途 |
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| DE69632859T2 (de) * | 1995-04-18 | 2005-07-14 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Verfahren zur Arzneistoffbehandlung von Liposomen Zusammensetzung |
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| WO2007005754A2 (en) | 2005-07-01 | 2007-01-11 | Alza Corporation | Liposomal delivery vehicle for hydrophobic drugs |
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| US20090196918A1 (en) * | 2008-02-01 | 2009-08-06 | University Of Kentucky Research Foundation | Liposomal formulations of hydrophobic lactone drugs in the presence of metal ions |
| CN102048693B (zh) * | 2009-10-26 | 2013-08-21 | 石药集团中奇制药技术（石家庄）有限公司 | 具有苯磺酸衍生物内水相的脂质体 |
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- 2015-04-08 CN CN201580019117.7A patent/CN106659795B/zh active Active
- 2015-04-08 JP JP2017504294A patent/JP6676035B2/ja active Active
- 2015-04-08 DK DK15722359.5T patent/DK3142642T3/en active
- 2015-04-08 WO PCT/IL2015/050376 patent/WO2015155773A1/en not_active Ceased
- 2015-04-08 EP EP15722359.5A patent/EP3142642B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3142642A1 (en) | 2017-03-22 |
| EP3142642B1 (en) | 2018-08-29 |
| WO2015155773A1 (en) | 2015-10-15 |
| JP2017513938A (ja) | 2017-06-01 |
| JP6676035B2 (ja) | 2020-04-08 |
| CN106659795A (zh) | 2017-05-10 |
| US20170027869A1 (en) | 2017-02-02 |
| CN106659795B (zh) | 2023-06-02 |
| US10004688B2 (en) | 2018-06-26 |
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