DK3126391T3 - ANTISTOFFER MOD HPA-1a - Google Patents
ANTISTOFFER MOD HPA-1a Download PDFInfo
- Publication number
- DK3126391T3 DK3126391T3 DK15713749T DK15713749T DK3126391T3 DK 3126391 T3 DK3126391 T3 DK 3126391T3 DK 15713749 T DK15713749 T DK 15713749T DK 15713749 T DK15713749 T DK 15713749T DK 3126391 T3 DK3126391 T3 DK 3126391T3
- Authority
- DK
- Denmark
- Prior art keywords
- antibodies against
- against hpa
- hpa
- antibodies
- Prior art date
Links
- 101001015004 Homo sapiens Integrin beta-3 Proteins 0.000 title 1
- 102000057154 human ITGB3 Human genes 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/34—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood group antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
- C07K16/2848—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta3-subunit-containing molecules, e.g. CD41, CD51, CD61
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/51—Complete heavy chain or Fd fragment, i.e. VH + CH1
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/515—Complete light chain, i.e. VL + CL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/54—F(ab')2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/38—Pediatrics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1405775.6A GB201405775D0 (en) | 2014-03-31 | 2014-03-31 | Antibodies |
| GBGB1417614.3A GB201417614D0 (en) | 2014-10-06 | 2014-10-06 | Antibodies |
| PCT/EP2015/057102 WO2015150417A1 (en) | 2014-03-31 | 2015-03-31 | ANTIBODIES AGAINST HPA-1a |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3126391T3 true DK3126391T3 (da) | 2019-11-25 |
Family
ID=52785093
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15713749T DK3126391T3 (da) | 2014-03-31 | 2015-03-31 | ANTISTOFFER MOD HPA-1a |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US10882919B2 (da) |
| EP (1) | EP3126391B1 (da) |
| AU (1) | AU2015239606C1 (da) |
| BR (1) | BR112016022508A2 (da) |
| CA (1) | CA2943857C (da) |
| CY (1) | CY1122728T1 (da) |
| DK (1) | DK3126391T3 (da) |
| ES (1) | ES2757596T3 (da) |
| HR (1) | HRP20192097T1 (da) |
| HU (1) | HUE047455T2 (da) |
| IL (1) | IL247988B1 (da) |
| LT (1) | LT3126391T (da) |
| ME (1) | ME03655B (da) |
| MX (1) | MX2016012620A (da) |
| NZ (1) | NZ724772A (da) |
| PL (1) | PL3126391T3 (da) |
| PT (1) | PT3126391T (da) |
| RS (1) | RS59704B1 (da) |
| RU (1) | RU2688627C2 (da) |
| SI (1) | SI3126391T1 (da) |
| WO (1) | WO2015150417A1 (da) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022212930A1 (en) * | 2021-04-02 | 2022-10-06 | Rallybio Ipa, Llc | Method of administering anti-hpa-1a gamma globulin |
| CA3224173A1 (en) * | 2021-07-01 | 2023-01-05 | Rallybio Ipa, Llc | Method of administering anti-hpa-1a monoclonal antibody |
| AU2022305071A1 (en) * | 2021-07-01 | 2024-01-18 | Rallybio Ipa, Llc | Administration of anti-hpa-1a antibodies |
| CA3235140A1 (en) * | 2021-11-08 | 2023-05-11 | Douglas L. Sheridan | Assays for quantification of anti-hpa-1a antibodies |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1990010457A1 (en) | 1989-03-14 | 1990-09-20 | New York University | Method of treating hiv infections using immunotoxins |
| DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
| EP0617706B1 (en) | 1991-11-25 | 2001-10-17 | Enzon, Inc. | Multivalent antigen-binding proteins |
| GB9223390D0 (en) | 1992-11-07 | 1992-12-23 | Common Services Agency | Anti-hpa1 testing |
| GB9505447D0 (en) | 1995-03-17 | 1995-05-03 | Common Services Agency | Competitive binding assay |
| WO1998055146A1 (en) | 1997-06-05 | 1998-12-10 | Johns Hopkins University | IDENTIFICATION OF HUMAN HEAVY CHAIN ANTIBODY FRAGMENT DIRECTED AGAINST HUMAN PLATELET ALLOANTIGEN 1a(HPA-1a) |
| GB9809951D0 (en) * | 1998-05-08 | 1998-07-08 | Univ Cambridge Tech | Binding molecules |
| US20030027207A1 (en) | 2000-02-29 | 2003-02-06 | Filpula David Ray | Anti-platelet binding proteins and polymer conjugates containing the same |
| JP3312204B2 (ja) | 2000-10-17 | 2002-08-05 | 学校法人 慶應義塾 | 血小板減少症の診断用キット |
| GB0315754D0 (en) | 2003-07-04 | 2003-08-13 | Univ Aberdeen | Pharmaceutical compositions |
| US20080261205A1 (en) | 2004-02-06 | 2008-10-23 | Canadian Blood Services | Method for the Simultaneous Determination of Blood Group and Platelet Antigen Genotypes |
| CA2590164A1 (en) | 2005-01-26 | 2006-08-03 | Amgen Fremont Inc. | Antibodies against interleukin-1 beta |
| NO345593B1 (no) | 2005-07-18 | 2021-05-03 | Amgen Inc | Humane anti-B7RP1 nøytraliserende antistoffer |
| US20090317413A1 (en) * | 2005-11-15 | 2009-12-24 | Cambridge Enterprise Limited | Detection of human platelet antigen (hpa) antibodies |
| US8840897B2 (en) | 2006-01-03 | 2014-09-23 | Prophylix Pharma As | Preparation useful for, and method for treatment of neonatal alloimmune thrombocytopenia (NAIT) |
| JP5042237B2 (ja) | 2006-02-07 | 2012-10-03 | スティフチュンク フュル ディアグノスティシュ フォルシュンク | 血小板抗原特異抗体の結合を中和するペプチドアプタマー並びにそれを含む診断及び治療への応用 |
| KR20080105111A (ko) | 2006-02-28 | 2008-12-03 | 온코세라피 사이언스 가부시키가이샤 | 항 ＥｐｈＡ４ 항체의 효과기 기능을 이용한 세포 손상 방법 |
| EP2006304A1 (en) * | 2007-06-22 | 2008-12-24 | Stiftung Für Diagnostische Forschung | Anti-HPA-5b monoclonal antibody |
| KR101624357B1 (ko) | 2007-05-25 | 2016-05-25 | 니혼 세키쥬지샤 | 신규한 ＧＰＩＩＩａ 유전자 |
| EP2025685B1 (en) | 2007-08-15 | 2013-06-19 | Canadian Blood Services | Monoclonal antibodies against BETA3 integrins |
| EP2450381B1 (en) | 2008-12-31 | 2019-07-03 | Bharat Serums And Vaccines Ltd. | Anti-RHD monoclonal antibodies |
| CN101892314B (zh) | 2010-06-22 | 2012-04-18 | 天津市秀鹏生物技术开发有限公司 | 用于检测人血小板同种抗原基因的引物组及试剂盒 |
| NO2796881T3 (da) * | 2013-04-26 | 2018-03-31 |
-
2015
- 2015-03-31 PT PT157137498T patent/PT3126391T/pt unknown
- 2015-03-31 CA CA2943857A patent/CA2943857C/en active Active
- 2015-03-31 MX MX2016012620A patent/MX2016012620A/es active IP Right Grant
- 2015-03-31 RU RU2016142718A patent/RU2688627C2/ru active
- 2015-03-31 PL PL15713749T patent/PL3126391T3/pl unknown
- 2015-03-31 ES ES15713749T patent/ES2757596T3/es active Active
- 2015-03-31 ME MEP-2019-328A patent/ME03655B/me unknown
- 2015-03-31 AU AU2015239606A patent/AU2015239606C1/en active Active
- 2015-03-31 NZ NZ724772A patent/NZ724772A/en unknown
- 2015-03-31 US US15/300,656 patent/US10882919B2/en active Active
- 2015-03-31 WO PCT/EP2015/057102 patent/WO2015150417A1/en active Application Filing
- 2015-03-31 DK DK15713749T patent/DK3126391T3/da active
- 2015-03-31 EP EP15713749.8A patent/EP3126391B1/en active Active
- 2015-03-31 IL IL247988A patent/IL247988B1/en unknown
- 2015-03-31 LT LTEP15713749.8T patent/LT3126391T/lt unknown
- 2015-03-31 RS RS20191490A patent/RS59704B1/sr unknown
- 2015-03-31 BR BR112016022508A patent/BR112016022508A2/pt not_active Application Discontinuation
- 2015-03-31 SI SI201531002T patent/SI3126391T1/sl unknown
- 2015-03-31 HU HUE15713749A patent/HUE047455T2/hu unknown
-
2019
- 2019-11-21 HR HRP20192097TT patent/HRP20192097T1/hr unknown
- 2019-11-21 CY CY20191101228T patent/CY1122728T1/el unknown
-
2020
- 2020-12-09 US US17/116,882 patent/US11725063B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| MX2016012620A (es) | 2017-04-06 |
| ES2757596T3 (es) | 2020-04-29 |
| CA2943857C (en) | 2023-07-11 |
| US20210189005A1 (en) | 2021-06-24 |
| IL247988A0 (en) | 2016-11-30 |
| US20170121422A1 (en) | 2017-05-04 |
| LT3126391T (lt) | 2020-02-10 |
| EP3126391B1 (en) | 2019-08-21 |
| RU2688627C2 (ru) | 2019-05-22 |
| HUE047455T2 (hu) | 2020-04-28 |
| AU2015239606A1 (en) | 2016-10-20 |
| RU2016142718A (ru) | 2018-05-07 |
| RU2016142718A3 (da) | 2018-10-18 |
| RS59704B1 (sr) | 2020-01-31 |
| SI3126391T1 (sl) | 2020-04-30 |
| BR112016022508A2 (pt) | 2017-10-10 |
| AU2015239606C1 (en) | 2020-08-27 |
| CY1122728T1 (el) | 2021-03-12 |
| CA2943857A1 (en) | 2015-10-08 |
| PT3126391T (pt) | 2019-11-27 |
| US10882919B2 (en) | 2021-01-05 |
| US11725063B2 (en) | 2023-08-15 |
| EP3126391A1 (en) | 2017-02-08 |
| PL3126391T3 (pl) | 2020-05-18 |
| AU2015239606B2 (en) | 2020-06-04 |
| NZ724772A (en) | 2023-03-31 |
| WO2015150417A1 (en) | 2015-10-08 |
| HRP20192097T1 (hr) | 2020-04-03 |
| ME03655B (me) | 2020-07-20 |
| IL247988B1 (en) | 2024-03-01 |
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