DK3116569T3 - Inhalator til aktivt tørpulver - Google Patents
Inhalator til aktivt tørpulver Download PDFInfo
- Publication number
- DK3116569T3 DK3116569T3 DK15715459.2T DK15715459T DK3116569T3 DK 3116569 T3 DK3116569 T3 DK 3116569T3 DK 15715459 T DK15715459 T DK 15715459T DK 3116569 T3 DK3116569 T3 DK 3116569T3
- Authority
- DK
- Denmark
- Prior art keywords
- capsule
- gas
- inhaler
- needle
- flow
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0003—Details of inhalators; Constructional features thereof with means for dispensing more than one drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
- A61M15/0033—Details of the piercing or cutting means
- A61M15/0035—Piercing means
- A61M15/0036—Piercing means hollow piercing means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
- A61M15/0033—Details of the piercing or cutting means
- A61M15/0041—Details of the piercing or cutting means with movable piercing or cutting means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/02—Sprayers or atomisers specially adapted for therapeutic purposes operated by air or other gas pressure applied to the liquid or other product to be sprayed or atomised
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/002—Details of inhalators; Constructional features thereof with air flow regulating means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
- A61M2016/0015—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
- A61M2016/0018—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
- A61M2016/0021—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with a proportional output signal, e.g. from a thermistor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
- A61M2205/3334—Measuring or controlling the flow rate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/50—General characteristics of the apparatus with microprocessors or computers
- A61M2205/502—User interfaces, e.g. screens or keyboards
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2206/00—Characteristics of a physical parameter; associated device therefor
- A61M2206/10—Flow characteristics
- A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2230/00—Measuring parameters of the user
- A61M2230/20—Blood composition characteristics
- A61M2230/205—Blood composition characteristics partial oxygen pressure (P-O2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2230/00—Measuring parameters of the user
- A61M2230/30—Blood pressure
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pulmonology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Claims (4)
- hvor aktiveringsmekanismen er aktiverbar for at klargøre inhalatoren (1300) ved bevægelse af nålen (122) i forhold til kapselkammeret (1311) langs med en vej til indføring af en del af nålen (122) hen over en første begrænsningslokalitet for kapselfastholdelsesvolumenet (1311) og ind i kapselfastholdelsesvolumenets (1311) indre; og hvor aktiveringsmekanismen fortsætter aktiveret bevægelse af nålen (122) langs med vejen i forhold til kapselkammeret (1311) med henblik på at bevæge delen af nålen (122) fra det indre til en anden begrænsningslokalitet for kapselfastholdelsesvolumenet (1311) og derefter at placere delen af nålen (402) med henblik på at strække sig forbi den anden begrænsningslokalitet for at udtræde af kapselfastholdelsesvolumenet (404); kendetegnet ved, at: yderligere fortsat aktivering af aktiveringsmekanismen tilbagetrækker delen af nålen (122), der indbefatter det mindst ene gasudtag (304), i det indre og væk fra den anden begrænsningslokalitet; og hvor inhalatoren (1300) er konfigureret til at dispergere tørpulvermedikamentet fra en udtrædelsesåbning (310), som efterlades åben af den tilbagetrukne nål i kapslens (420) væg på den anden begrænsningslokalitet, mens delen af nålen (122), der indbefatter det mindst ene gasudtag (304), forbliver tilbagetrukket i det indre og, når inhalatoren (1300) er klargjort med kapslen (210), er placeret inde i kapselfastholdelsesvolumenet (1311).
- 13. Kit, der omfatter modulet (1302) ifølge krav 12 og mindst ti kapsler (210), som indeholder tørpulvermedikament.
- 14. Fremgangsmåde til fremstilling afen inhalatorkapsel (210), som indeholder tørpulvermedikament med et kapseludtag (310) til medikamentet, hvilken fremgangsmåde omfatter: indføring af en nål (122), der omfatter et gaslumen med mindst ét gasudtag (304), ind i kapslens (210) indre; og punktering af en væg i inhalatorkapslen (210) ved presning af nålen (122) mod væggen fra kapslens indre med henblik på at definere kapseludtaget (310); kendetegnet ved: tilbagetrækning af nålen (122) med henblik på at genåbne kapseludtaget (310), idet det mindst ene gasudtag (304) anbringes inde i kapslens indre; og styring af gas ind i det mindst ene gasudtag (304), mens den forbliver i det indre, og kapseludtaget (310) genåbnes, hvorved tørpulvermedikamentet frigives fra kapslen (210).
- 15. Fremgangsmåde ifølge krav 14, hvor ikke mere end 20 % af kapslens (210) væg, som forskubbes for at danne kapseludtaget (310), er inde i kapslens indre efter dannelse af kapseludtaget (310).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461950256P | 2014-03-10 | 2014-03-10 | |
PCT/IL2015/050248 WO2015136529A1 (en) | 2014-03-10 | 2015-03-10 | Active dry powder inhaler |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3116569T3 true DK3116569T3 (da) | 2018-04-16 |
Family
ID=52823742
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK15715459.2T DK3116569T3 (da) | 2014-03-10 | 2015-03-10 | Inhalator til aktivt tørpulver |
Country Status (8)
Country | Link |
---|---|
US (1) | US10166350B2 (da) |
EP (1) | EP3116569B1 (da) |
CN (1) | CN106456914A (da) |
DK (1) | DK3116569T3 (da) |
ES (1) | ES2667518T3 (da) |
NO (1) | NO2709641T3 (da) |
TW (1) | TW201538187A (da) |
WO (1) | WO2015136529A1 (da) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2014164897A2 (en) | 2013-03-11 | 2014-10-09 | Collins John R | Inhalator device and method |
NO2709641T3 (da) | 2014-03-10 | 2018-05-12 | ||
CN115530445A (zh) * | 2014-11-19 | 2022-12-30 | 富特姆投资有限公司 | 用于使来自非可燃吸烟制品的气溶胶功能化的方法、组合物和装置 |
CN104666062A (zh) * | 2015-02-07 | 2015-06-03 | 深圳市中和风科技开发有限公司 | 可读卡式美容仪 |
US11285285B2 (en) | 2016-05-03 | 2022-03-29 | Pneuma Respiratory, Inc. | Systems and methods comprising a droplet delivery device and a breathing assist device for therapeutic treatment |
WO2017192773A1 (en) | 2016-05-03 | 2017-11-09 | Pneuma Respiratory, Inc. | Methods for treatment of pulmonary lung diseases with improved therapeutic efficacy and improved dose efficiency |
US11285274B2 (en) | 2016-05-03 | 2022-03-29 | Pneuma Respiratory, Inc. | Methods for the systemic delivery of therapeutic agents to the pulmonary system using a droplet delivery device |
CN109475709B (zh) | 2016-05-03 | 2022-12-27 | 精呼吸股份有限公司 | 使用液滴输送装置生成液滴并将其输送到肺部系统的方法 |
ES2884802T3 (es) * | 2016-11-18 | 2021-12-13 | Norton Waterford Ltd | Dispositivo de administración de fármacos con componentes electrónicos |
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CA3064005C (en) * | 2017-05-19 | 2023-03-07 | Pneuma Respiratory, Inc. | Dry powder delivery device and methods of use |
WO2018222810A1 (en) | 2017-05-31 | 2018-12-06 | Virginia Commonwealth University | Devices, systems, and methods for dry powder therapies |
JP2020536614A (ja) | 2017-10-04 | 2020-12-17 | ニューマ・リスパイラトリー・インコーポレイテッド | 呼吸により電気的に作動するインライン液滴送達装置および使用方法 |
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CA3082192A1 (en) | 2017-11-08 | 2019-05-16 | Pneuma Respiratory, Inc. | Electronic breath actuated in-line droplet delivery device with small volume ampoule and methods of use |
JP7241892B2 (ja) * | 2019-01-24 | 2023-03-17 | イーライ リリー アンド カンパニー | 経鼻薬品送達デバイス |
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CN103442758B (zh) * | 2011-03-15 | 2016-03-23 | 诺华股份有限公司 | 吸入器 |
DE202011104129U1 (de) | 2011-08-08 | 2011-12-07 | Markus Mezger | Nadel zur Öffnung pharmazeutischer Kapseln |
NO2709641T3 (da) | 2014-03-10 | 2018-05-12 |
-
2012
- 2012-05-16 NO NO12785909A patent/NO2709641T3/no unknown
-
2015
- 2015-03-10 US US15/125,173 patent/US10166350B2/en not_active Expired - Fee Related
- 2015-03-10 WO PCT/IL2015/050248 patent/WO2015136529A1/en active Application Filing
- 2015-03-10 ES ES15715459.2T patent/ES2667518T3/es active Active
- 2015-03-10 TW TW104107600A patent/TW201538187A/zh unknown
- 2015-03-10 CN CN201580024505.4A patent/CN106456914A/zh active Pending
- 2015-03-10 EP EP15715459.2A patent/EP3116569B1/en active Active
- 2015-03-10 DK DK15715459.2T patent/DK3116569T3/da active
Also Published As
Publication number | Publication date |
---|---|
CN106456914A (zh) | 2017-02-22 |
WO2015136529A1 (en) | 2015-09-17 |
TW201538187A (zh) | 2015-10-16 |
NO2709641T3 (da) | 2018-05-12 |
EP3116569B1 (en) | 2018-02-28 |
EP3116569A1 (en) | 2017-01-18 |
US20170165439A1 (en) | 2017-06-15 |
ES2667518T3 (es) | 2018-05-11 |
US10166350B2 (en) | 2019-01-01 |
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