DK3110975T3 - Fremgangsmåder til analyse af somatiske mobile elementer og anvendelser deraf - Google Patents

Fremgangsmåder til analyse af somatiske mobile elementer og anvendelser deraf Download PDF

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DK3110975T3
DK3110975T3 DK15754498.2T DK15754498T DK3110975T3 DK 3110975 T3 DK3110975 T3 DK 3110975T3 DK 15754498 T DK15754498 T DK 15754498T DK 3110975 T3 DK3110975 T3 DK 3110975T3
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somatic
analysis
methods
mobile elements
mobile
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DK15754498.2T
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Keith Brown
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Jumpcode Genomics Inc
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
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    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
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    • A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
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    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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DK15754498.2T 2014-02-27 2015-02-27 Fremgangsmåder til analyse af somatiske mobile elementer og anvendelser deraf DK3110975T3 (da)

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US201461945791P 2014-02-27 2014-02-27
PCT/US2015/018115 WO2015131110A1 (en) 2014-02-27 2015-02-27 Methods for analysis of somatic mobile elements, and uses thereof

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US (2) US20160376663A1 (cg-RX-API-DMAC7.html)
EP (2) EP3110975B1 (cg-RX-API-DMAC7.html)
JP (2) JP6996844B2 (cg-RX-API-DMAC7.html)
CN (2) CN106414770A (cg-RX-API-DMAC7.html)
AU (2) AU2015222802B2 (cg-RX-API-DMAC7.html)
CA (3) CA3214905A1 (cg-RX-API-DMAC7.html)
DK (1) DK3110975T3 (cg-RX-API-DMAC7.html)
ES (1) ES2894048T3 (cg-RX-API-DMAC7.html)
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Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2734621B1 (en) 2011-07-22 2019-09-04 President and Fellows of Harvard College Evaluation and improvement of nuclease cleavage specificity
US10323279B2 (en) 2012-08-14 2019-06-18 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10584381B2 (en) 2012-08-14 2020-03-10 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10273541B2 (en) 2012-08-14 2019-04-30 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10221442B2 (en) 2012-08-14 2019-03-05 10X Genomics, Inc. Compositions and methods for sample processing
US10752949B2 (en) 2012-08-14 2020-08-25 10X Genomics, Inc. Methods and systems for processing polynucleotides
US9951386B2 (en) 2014-06-26 2018-04-24 10X Genomics, Inc. Methods and systems for processing polynucleotides
US11591637B2 (en) 2012-08-14 2023-02-28 10X Genomics, Inc. Compositions and methods for sample processing
WO2014028537A1 (en) 2012-08-14 2014-02-20 10X Technologies, Inc. Microcapsule compositions and methods
US9701998B2 (en) 2012-12-14 2017-07-11 10X Genomics, Inc. Methods and systems for processing polynucleotides
EP2931919B1 (en) 2012-12-14 2019-02-20 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10533221B2 (en) 2012-12-14 2020-01-14 10X Genomics, Inc. Methods and systems for processing polynucleotides
AU2014214682B2 (en) 2013-02-08 2018-07-26 10X Genomics, Inc. Polynucleotide barcode generation
CN111394426B (zh) 2013-05-23 2024-05-10 斯坦福大学托管董事会 用于个人表观基因组学的至天然染色质的转座
US20180113137A1 (en) * 2013-10-18 2018-04-26 Tcm Biotech International Corp. Method for detecting the quantity of biomarker and identifying disease status
PL3102722T3 (pl) 2014-02-04 2021-03-08 Jumpcode Genomics, Inc. Frakcjonowanie genomu
MX2016013156A (es) 2014-04-10 2017-02-14 10X Genomics Inc Dispositivos, sistemas y metodos fluidicos, para encapsular y dividir reactivos, y aplicaciones de los mismos.
WO2015200869A1 (en) 2014-06-26 2015-12-30 10X Genomics, Inc. Analysis of nucleic acid sequences
MX2016016902A (es) 2014-06-26 2017-03-27 10X Genomics Inc Metodos para analizar acidos nucleicos de celulas individuales o poblaciones de celulas.
US12312640B2 (en) 2014-06-26 2025-05-27 10X Genomics, Inc. Analysis of nucleic acid sequences
BR112017008877A2 (pt) 2014-10-29 2018-07-03 10X Genomics Inc métodos e composições para sequenciamento de ácido nucleico-alvo
US9975122B2 (en) 2014-11-05 2018-05-22 10X Genomics, Inc. Instrument systems for integrated sample processing
MX367432B (es) 2015-01-12 2019-08-08 10X Genomics Inc Procesos y sistemas para la preparación de bibliotecas de secuenciación de ácido nucleico y bibliotecas preparadas con estos.
WO2016137973A1 (en) 2015-02-24 2016-09-01 10X Genomics Inc Partition processing methods and systems
BR112017018054A2 (pt) 2015-02-24 2018-07-24 10X Genomics Inc métodos para a cobertura de sequências de ácidos nucleicos direcionadas
EP3262175A4 (en) 2015-02-25 2018-10-31 Jumpcode Genomics, Inc. Methods and compositions for in silico long read sequencing
KR102723865B1 (ko) 2015-12-04 2024-10-29 10엑스 제노믹스, 인크. 핵산 분석을 위한 방법 및 조성물
US11339427B2 (en) 2016-02-12 2022-05-24 Jumpcode Genomics, Inc. Method for target specific RNA transcription of DNA sequences
WO2017197343A2 (en) 2016-05-12 2017-11-16 10X Genomics, Inc. Microfluidic on-chip filters
WO2017197338A1 (en) 2016-05-13 2017-11-16 10X Genomics, Inc. Microfluidic systems and methods of use
CN105886645A (zh) * 2016-05-27 2016-08-24 福建爱我健康生物科技有限公司 一种用于评估皮肤抗皱情况的引物和探针及试剂盒
US10011872B1 (en) 2016-12-22 2018-07-03 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10550429B2 (en) 2016-12-22 2020-02-04 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10815525B2 (en) 2016-12-22 2020-10-27 10X Genomics, Inc. Methods and systems for processing polynucleotides
EP4310183B1 (en) 2017-01-30 2025-07-09 10X Genomics, Inc. Methods and systems for droplet-based single cell barcoding
US12264411B2 (en) 2017-01-30 2025-04-01 10X Genomics, Inc. Methods and systems for analysis
US20180340169A1 (en) 2017-05-26 2018-11-29 10X Genomics, Inc. Single cell analysis of transposase accessible chromatin
CN116064732A (zh) 2017-05-26 2023-05-05 10X基因组学有限公司 转座酶可接近性染色质的单细胞分析
CN107245529A (zh) * 2017-08-08 2017-10-13 杭州千麦医学检验所有限公司 血液病融合基因筛查方法
SG11201913654QA (en) 2017-11-15 2020-01-30 10X Genomics Inc Functionalized gel beads
US10829815B2 (en) 2017-11-17 2020-11-10 10X Genomics, Inc. Methods and systems for associating physical and genetic properties of biological particles
CA3089756A1 (en) 2018-01-29 2019-08-01 St. Jude Children's Research Hospital, Inc. Method for nucleic acid amplification
EP3749740B1 (en) 2018-02-05 2023-08-30 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for multiplexed measurements in single and ensemble cells
CN108384846B (zh) * 2018-02-28 2020-06-16 固安博健生物技术有限公司 C11orf95基因及其表达产物在诊治类风湿性关节炎和骨关节炎方面的应用
WO2019195166A1 (en) 2018-04-06 2019-10-10 10X Genomics, Inc. Systems and methods for quality control in single cell processing
CN112941155B (zh) * 2018-05-14 2023-07-14 北京艾克伦医疗科技有限公司 具有茎环结构的dna引物对及其应用
US12331320B2 (en) 2018-10-10 2025-06-17 The Research Foundation For The State University Of New York Genome edited cancer cell vaccines
KR102102107B1 (ko) * 2019-05-30 2020-04-20 단국대학교 천안캠퍼스 산학협력단 이동성 유전인자 SINE 선택적 발굴을 위한 HiSeq 시퀀서 기반의 DNA 라이브러리 제작 방법
TWI881992B (zh) * 2019-07-30 2025-05-01 大學健康網絡 Ｔ細胞受體及其使用方法
WO2021042066A1 (en) * 2019-08-30 2021-03-04 Foundation Medicine, Inc. Kmt2a-maml2 fusion molecules and uses thereof
US20250230430A1 (en) * 2022-03-24 2025-07-17 Nanjing Legend Biotech Co., Ltd. Methods for preparing dna libraries and detecting retroviral integration sites

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU9596098A (en) * 1997-09-29 1999-04-23 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Display technique for identifying line-1 insertion site polymorphisms
JP2002540799A (ja) * 1999-04-01 2002-12-03 マクギル・ユニヴァーシティ 新規なタイプのトランスポゾンに基づいた遺伝子マーカー
AU6720700A (en) * 1999-09-07 2001-04-10 Decode Genetics Ehf. Detection of alterations in a gene by long range pcr using human mobile elements
US20050238658A1 (en) * 2002-03-05 2005-10-27 Maskell Duncan J Transposon
US20060035245A1 (en) * 2004-04-20 2006-02-16 Ason Brandon L Modulators of enzymatic nucleic acid elements mobilization
EP1960541B1 (en) * 2005-11-14 2013-04-24 Keygene N.V. Method for high throughput screening of transposon tagging populations and massive parallel sequence identification of insertion sites
WO2008134596A2 (en) * 2007-04-25 2008-11-06 John Wayne Cancer Institute Use of methylated or unmethylated line-i dna as a cancer marker
US20120252015A1 (en) * 2011-02-18 2012-10-04 Bio-Rad Laboratories Methods and compositions for detecting genetic material
JP5985390B2 (ja) * 2009-04-02 2016-09-06 フリューダイム・コーポレイション 標的核酸にバーコードを付加するためのマルチプライマー増幅方法
US9028561B2 (en) * 2009-05-05 2015-05-12 Milliken & Company Bluing composition and method for treating textile articles using the same
US20130315886A1 (en) * 2009-08-05 2013-11-28 Salk Institute For Biological Studies Retroelements and mental disorders and methods of measuring l1 retrotransposition
WO2012048113A2 (en) * 2010-10-07 2012-04-12 The General Hospital Corporation Biomarkers of cancer

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JP6996844B2 (ja) 2022-02-03
US20230193401A1 (en) 2023-06-22
PL3110975T3 (pl) 2021-12-13
EP3110975A1 (en) 2017-01-04
JP2017512491A (ja) 2017-05-25
EP3943615A1 (en) 2022-01-26
WO2015131110A1 (en) 2015-09-03
CA3212153A1 (en) 2025-07-07
EP3110975B1 (en) 2021-07-07
EP3110975A4 (en) 2017-12-06
US20160376663A1 (en) 2016-12-29
AU2015222802B2 (en) 2021-07-01
AU2021240134B2 (en) 2024-08-29
CN106414770A (zh) 2017-02-15
ES2894048T3 (es) 2022-02-11
CA2940669C (en) 2023-10-03
CA3214905A1 (en) 2015-09-03
JP2020156491A (ja) 2020-10-01
CA2940669A1 (en) 2015-09-03
CN114250301A (zh) 2022-03-29
AU2021240134A1 (en) 2021-10-28

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