DK3076949T3 - Fremgangsmåde til isolering af kræftcelle-afledte eksosomer - Google Patents
Fremgangsmåde til isolering af kræftcelle-afledte eksosomer Download PDFInfo
- Publication number
- DK3076949T3 DK3076949T3 DK14867768T DK14867768T DK3076949T3 DK 3076949 T3 DK3076949 T3 DK 3076949T3 DK 14867768 T DK14867768 T DK 14867768T DK 14867768 T DK14867768 T DK 14867768T DK 3076949 T3 DK3076949 T3 DK 3076949T3
- Authority
- DK
- Denmark
- Prior art keywords
- cancer cell
- derived exosomes
- isolating cancer
- isolating
- exosomes
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
- G01N33/57585—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds identifiable in body fluids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5063—Compounds of unknown constitution, e.g. material from plants or animals
- A61K9/5068—Cell membranes or bacterial membranes enclosing drugs
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Virology (AREA)
- Biophysics (AREA)
- Developmental Biology & Embryology (AREA)
- General Engineering & Computer Science (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361911863P | 2013-12-04 | 2013-12-04 | |
| PCT/US2014/068630 WO2015085096A1 (en) | 2013-12-04 | 2014-12-04 | Analysis of genomic dna, rna, and proteins in exosomes for diagnosis and theranosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3076949T3 true DK3076949T3 (da) | 2019-11-25 |
Family
ID=53274132
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK14867768T DK3076949T3 (da) | 2013-12-04 | 2014-12-04 | Fremgangsmåde til isolering af kræftcelle-afledte eksosomer |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US9921223B2 (https=) |
| EP (1) | EP3076949B1 (https=) |
| JP (3) | JP2017501694A (https=) |
| AU (3) | AU2014360344B2 (https=) |
| CA (1) | CA2936100A1 (https=) |
| DK (1) | DK3076949T3 (https=) |
| HR (1) | HRP20192131T1 (https=) |
| HU (1) | HUE046489T2 (https=) |
| LT (1) | LT3076949T (https=) |
| NZ (1) | NZ721720A (https=) |
| SI (1) | SI3076949T1 (https=) |
| WO (1) | WO2015085096A1 (https=) |
| ZA (1) | ZA201604468B (https=) |
Families Citing this family (62)
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| US11660317B2 (en) | 2004-11-08 | 2023-05-30 | The Johns Hopkins University | Compositions comprising cardiosphere-derived cells for use in cell therapy |
| WO2006116362A2 (en) | 2005-04-25 | 2006-11-02 | The Trustees Of Boston University | Structured substrates for optical surface profiling |
| US11286463B2 (en) | 2012-03-08 | 2022-03-29 | Advanced ReGen Medical Technologies, LLC | Reprogramming of aged adult stem cells |
| AU2013302799B2 (en) | 2012-08-13 | 2018-03-01 | Cedars-Sinai Medical Center | Exosomes and micro-ribonucleic acids for tissue regeneration |
| US11180812B2 (en) | 2012-08-17 | 2021-11-23 | Cornell University | Use of DNA in circulating exosomes as a diagnostic marker for metastatic disease |
| CN105264092B (zh) | 2013-03-15 | 2019-02-22 | 得克萨斯州大学系统董事会 | 用于诊断和疗法的外来体中的miRNA生物发生 |
| JP2017501694A (ja) * | 2013-12-04 | 2017-01-19 | ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム | 診断および療法のためのエキソソーム中のゲノムｄｎａ、ｒｎａおよびタンパク質の分析 |
| US10772911B2 (en) | 2013-12-20 | 2020-09-15 | Advanced ReGen Medical Technologies, LLC | Cell free compositions for cellular restoration and methods of making and using same |
| CR20160307A (es) | 2013-12-20 | 2016-11-08 | Advanced Regen Medical Tech Llc | Composiciones para la restauración de células y métodos para la preparación y utilización de las mismas |
| US10844436B2 (en) * | 2014-04-01 | 2020-11-24 | Cornell University | Use of double-stranded DNA in exosomes: a novel biomarker in cancer detection |
| CA2962444C (en) | 2014-10-03 | 2023-09-05 | Cedars-Sinai Medical Center | Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of muscular dystrophy |
| US11397182B2 (en) | 2014-10-07 | 2022-07-26 | Cornell University | Methods for prognosing and preventing metastatic liver disease |
| US11971402B2 (en) | 2015-04-24 | 2024-04-30 | Cornell University | Methods and reagents for determination and treatment of organotropic metastasis |
| US11339441B2 (en) * | 2015-05-12 | 2022-05-24 | The Research Foundation For The State University Of New York | Profiling chemically modified DNA/RNA units for disease and cancer diagnosis |
| WO2016201064A1 (en) | 2015-06-09 | 2016-12-15 | The Board Of Regents Of The University Of Texas System | Diagnostic test for early stage cancer |
| US20180177727A1 (en) | 2015-06-10 | 2018-06-28 | Board Of Regents, The University Of Texas System | Use of exosomes for the treatment of disease |
| CN114217058A (zh) | 2015-09-22 | 2022-03-22 | 波士顿大学董事会 | 纳米囊泡的多重表型分析 |
| GB201518466D0 (en) * | 2015-10-19 | 2015-12-02 | Cizzle Biotechnology Ltd | Use |
| EP3402543B1 (en) | 2016-01-11 | 2021-09-08 | Cedars-Sinai Medical Center | Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of heart failure with preserved ejection fraction |
| JP7033082B2 (ja) * | 2016-02-05 | 2022-03-09 | ナノビュー バイオサイエンシズ インコーポレイテッド | 表面マーカーを有するエキソソームの検出 |
| RU2018136151A (ru) * | 2016-03-15 | 2020-04-15 | Кодиак Байосайнсиз, Инк. | Терапевтические мембранные везикулы |
| EP3436081A4 (en) | 2016-04-29 | 2019-07-24 | Advanced Regen Medical Technologies, LLC | Microrna compositions and methods of making and using same |
| WO2017210652A1 (en) | 2016-06-03 | 2017-12-07 | Cedars-Sinai Medical Center | Cdc-derived exosomes for treatment of ventricular tachyarrythmias |
| WO2017223186A1 (en) * | 2016-06-21 | 2017-12-28 | Nant Holdings Ip, Llc | Exosome-guided treatment of cancer |
| CN106124282B (zh) | 2016-07-26 | 2019-07-16 | 广州海力特生物科技有限公司 | 一种叠层离心过滤分离提取外泌体的方法 |
| US20180067121A1 (en) * | 2016-09-06 | 2018-03-08 | Nanoco Technologies Ltd. | Exosome-conjugated quantum dot nanoparticles and methods of detecting exosomes and cancer using same |
| US11541078B2 (en) | 2016-09-20 | 2023-01-03 | Cedars-Sinai Medical Center | Cardiosphere-derived cells and their extracellular vesicles to retard or reverse aging and age-related disorders |
| CN110650728B (zh) * | 2017-03-21 | 2023-06-23 | 埃索普罗瑟医疗有限公司 | 含有用于治疗的肿瘤抑制蛋白的天然细胞衍生的囊泡 |
| GB2560897A (en) | 2017-03-23 | 2018-10-03 | Lotvall Jan | Tissue-derived extracellular vesicles and their use as diagnostics |
| EP4699658A2 (en) | 2017-04-19 | 2026-02-25 | Cedars-Sinai Medical Center | Methods and compositions for treating skeletal muscular dystrophy |
| CN107338306A (zh) * | 2017-07-23 | 2017-11-10 | 嘉兴允英医学检验有限公司 | 一种用于GPC1mRNA表达检测的试剂盒 |
| JP2020529477A (ja) * | 2017-08-04 | 2020-10-08 | シーダーズ—シナイ メディカル センター | がんの治療及び防止のためのカルディオスフィア由来細胞及びその細胞外小胞 |
| GB2574785A (en) | 2017-09-15 | 2019-12-25 | Jan Loetvall | Method and system for identifying membrane proteins on extracellular vesicles |
| WO2019094692A2 (en) | 2017-11-09 | 2019-05-16 | The Trustees Of The University Of Pennsylvania | Extracellular vesicle proteins and their use for cancer diagnosis, predicting response to therapy, and treatment |
| WO2019109077A1 (en) | 2017-12-01 | 2019-06-06 | Cornell University | Nanoparticles and distinct exosome subsets for detection and treatment of cancer |
| CA3084821A1 (en) | 2017-12-15 | 2019-06-20 | Board Of Regents, The University Of Texas System | Methods and compositions for treating cancer using exosomes-associated gene editing |
| US11660355B2 (en) | 2017-12-20 | 2023-05-30 | Cedars-Sinai Medical Center | Engineered extracellular vesicles for enhanced tissue delivery |
| AU2018394238A1 (en) * | 2017-12-28 | 2020-06-18 | Lonza Sales Ag | Exosomes for immuno-oncology and anti-inflammatory therapy |
| US10717981B2 (en) | 2018-01-18 | 2020-07-21 | Advanced ReGen Medical Technologies, LLC | Therapeutic compositions and methods of making and using the same |
| US12146137B2 (en) | 2018-02-05 | 2024-11-19 | Cedars-Sinai Medical Center | Methods for therapeutic use of exosomes and Y-RNAS |
| US12241888B2 (en) | 2018-03-14 | 2025-03-04 | Children's Medical Center Corporation | Platform for assessment of the transcytosis of extracellular vesicles across endothelial barriers and uses thereof |
| JP7813099B2 (ja) * | 2018-03-28 | 2026-02-12 | ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム | 治療用物質を標的送達するためのエキソソームの使用法 |
| EP3775258A4 (en) * | 2018-03-28 | 2022-01-26 | Board of Regents, The University of Texas System | IDENTIFICATION OF EPIGENETIC ALTERATIONS IN DNA ISOLATED FROM EXOSOMES |
| CN112236130A (zh) * | 2018-04-09 | 2021-01-15 | 得克萨斯州大学系统董事会 | 使用外排体对癌基因的治疗性靶向 |
| EP3788150A4 (en) * | 2018-05-04 | 2022-01-26 | Sigma-Aldrich Co. LLC | PRODUCTION OF RECOMBINANT PROTEINS WITH REDUCED LEVELS OF HOST CELL PROTEINS |
| EP3803332A1 (en) | 2018-06-01 | 2021-04-14 | NanoView Biosciences, Inc. | Compositions, systems, and methods for enhanced label-free and fluorescence - based detection of nanoparticles |
| IL269897B2 (en) | 2018-11-15 | 2023-08-01 | Sternum Ltd | Implementing control flow correctness verification in code intermediate files |
| US11766484B2 (en) | 2019-01-03 | 2023-09-26 | International Business Machines Corporation | Exosome vessels for delivery of molecular cargo |
| WO2020146390A1 (en) | 2019-01-09 | 2020-07-16 | Exocure Biosciences, Inc. | Bacteria-derived vesicles and uses thereof |
| US20220113313A1 (en) * | 2019-02-01 | 2022-04-14 | NanoView Biosciences, Inc. | Systems and methods for vesicle cargo labeling and detection |
| AU2020218358A1 (en) * | 2019-02-08 | 2021-08-26 | Board Of Regents, The University Of Texas System | Isolation and detection of exosome-associated microbiome for diagnostic and therapeutic purposes |
| CN114080232A (zh) * | 2019-03-21 | 2022-02-22 | 科迪亚克生物科学公司 | 用于疫苗递送的细胞外囊泡 |
| WO2020219699A1 (en) * | 2019-04-23 | 2020-10-29 | Children's Medical Center Corporation | Use of rab7 gtpase (rab7) inhibitors in enhancing permeability of the blood brain barrier (bbb) |
| EP4013392B1 (en) | 2019-09-13 | 2026-04-29 | Exocure Sweden AB | Use of ghost nanovesicles as therapeutics |
| JP7462452B2 (ja) * | 2020-03-27 | 2024-04-05 | 株式会社日立製作所 | 培養細胞の分化レベルを評価するための評価装置および評価方法、並びに自動細胞培養システム |
| CN112698033A (zh) * | 2020-12-09 | 2021-04-23 | 复旦大学附属中山医院 | 一种血源性外泌体her2的检测方法及其应用 |
| US20230340606A1 (en) * | 2021-09-09 | 2023-10-26 | The Regents Of The University Of California | Extracellular repetitive rna biomarkers of mutant kras cancers |
| WO2023081099A1 (en) * | 2021-11-02 | 2023-05-11 | Daniel Kim | Extracellular rna signatures of mutant kras(g12c) cancers |
| WO2023210644A1 (ja) * | 2022-04-26 | 2023-11-02 | 国立大学法人東京大学 | がん細胞由来細胞外小胞群の単離濃縮方法、分析方法、薬剤選択方法、キット、及び抗がん剤 |
| US20250290919A1 (en) * | 2022-05-06 | 2025-09-18 | The Trustees Of The University Of Pennsylvania | Ultrasensitive single extracellular vesicle detection using high throughput droplet digital enzyme-linked immunosorbent assay |
| WO2024047441A1 (en) * | 2022-09-01 | 2024-03-07 | Fundação D. Anna De Sommer Champalimaud E Dr. Carlos Montez Champalimaud - Centro De Investigação Da Fundação Champalimaud | Method for monitoring tumor burden in subjects during therapeutic intervention |
| WO2024073671A1 (en) * | 2022-09-30 | 2024-04-04 | Foundation Medicine, Inc. | Systems and methods for processing clinico-genomic data |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US5824311A (en) | 1987-11-30 | 1998-10-20 | Trustees Of The University Of Pennsylvania | Treatment of tumors with monoclonal antibodies against oncogene antigens |
| US4870287A (en) | 1988-03-03 | 1989-09-26 | Loma Linda University Medical Center | Multi-station proton beam therapy system |
| US5846945A (en) | 1993-02-16 | 1998-12-08 | Onyx Pharmaceuticals, Inc. | Cytopathic viruses for therapy and prophylaxis of neoplasia |
| US5801005A (en) | 1993-03-17 | 1998-09-01 | University Of Washington | Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated |
| GB9506466D0 (en) | 1994-08-26 | 1995-05-17 | Prolifix Ltd | Cell cycle regulated repressor and dna element |
| US5760395A (en) | 1996-04-18 | 1998-06-02 | Universities Research Assoc., Inc. | Method and apparatus for laser-controlled proton beam radiology |
| US5739169A (en) | 1996-05-31 | 1998-04-14 | Procept, Incorporated | Aromatic compounds for inhibiting immune response |
| US20030064949A1 (en) * | 1998-02-17 | 2003-04-03 | Loretta Nielsen | Combined tumor suppressor gene therapy and chemotherapy in the treatment of neoplasms |
| FR2766205B1 (fr) | 1997-07-16 | 2002-08-30 | Inst Nat Sante Rech Med | Nouveau procede de sensibilisation de cellules presentatrices d'antigene et nouveaux moyens pour la mise en oeuvre du procede |
| KR100519384B1 (ko) | 2002-08-13 | 2005-10-06 | (주)누백스 | 유전자 이입을 이용한 엑소좀의 제조방법 및 상기 엑소좀의 용도 |
| EP2245199B1 (en) * | 2008-02-01 | 2013-11-13 | The General Hospital Corporation | Use of microvesicles in diagnosis, prognosis and treatment of medical diseases and conditions |
| US20120196285A1 (en) * | 2011-01-31 | 2012-08-02 | Esoterix Genetic Laboratories, Llc | Methods for Enriching Microparticles or Nucleic Acids Using Binding Molecules |
| US9777042B2 (en) * | 2011-12-15 | 2017-10-03 | Morehouse School Of Medicine | Method of purifying HIV/SIV Nef from exosomal fusion proteins |
| US9309559B2 (en) * | 2013-04-15 | 2016-04-12 | Albert Einstein College Of Medicine, Inc. | Simultaneous extraction of DNA and RNA from FFPE tissues |
| JP2017501694A (ja) * | 2013-12-04 | 2017-01-19 | ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム | 診断および療法のためのエキソソーム中のゲノムｄｎａ、ｒｎａおよびタンパク質の分析 |
-
2014
- 2014-12-04 JP JP2016536918A patent/JP2017501694A/ja not_active Ceased
- 2014-12-04 LT LT14867768T patent/LT3076949T/lt unknown
- 2014-12-04 WO PCT/US2014/068630 patent/WO2015085096A1/en not_active Ceased
- 2014-12-04 HU HUE14867768A patent/HUE046489T2/hu unknown
- 2014-12-04 HR HRP20192131TT patent/HRP20192131T1/hr unknown
- 2014-12-04 EP EP14867768.5A patent/EP3076949B1/en active Active
- 2014-12-04 CA CA2936100A patent/CA2936100A1/en active Pending
- 2014-12-04 NZ NZ721720A patent/NZ721720A/en not_active IP Right Cessation
- 2014-12-04 AU AU2014360344A patent/AU2014360344B2/en not_active Ceased
- 2014-12-04 US US15/101,857 patent/US9921223B2/en active Active
- 2014-12-04 DK DK14867768T patent/DK3076949T3/da active
- 2014-12-04 SI SI201431412T patent/SI3076949T1/sl unknown
-
2016
- 2016-06-30 ZA ZA2016/04468A patent/ZA201604468B/en unknown
-
2017
- 2017-11-01 US US15/801,269 patent/US10598665B2/en active Active
-
2019
- 2019-01-30 AU AU2019200573A patent/AU2019200573A1/en not_active Abandoned
- 2019-02-25 AU AU2019201290A patent/AU2019201290A1/en not_active Withdrawn
- 2019-08-13 JP JP2019148579A patent/JP2019198327A/ja not_active Withdrawn
-
2020
- 2020-03-04 US US16/809,300 patent/US20200200755A1/en not_active Abandoned
-
2021
- 2021-07-02 JP JP2021110830A patent/JP7138372B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20200200755A1 (en) | 2020-06-25 |
| US10598665B2 (en) | 2020-03-24 |
| HUE046489T2 (hu) | 2020-03-30 |
| JP2021177760A (ja) | 2021-11-18 |
| AU2014360344A1 (en) | 2016-07-14 |
| LT3076949T (lt) | 2019-12-10 |
| US9921223B2 (en) | 2018-03-20 |
| AU2019200573A1 (en) | 2019-02-21 |
| SI3076949T1 (sl) | 2020-01-31 |
| WO2015085096A1 (en) | 2015-06-11 |
| ZA201604468B (en) | 2024-01-31 |
| EP3076949A4 (en) | 2017-11-22 |
| AU2014360344B2 (en) | 2018-11-29 |
| CA2936100A1 (en) | 2015-06-11 |
| NZ721720A (en) | 2022-04-29 |
| JP7138372B2 (ja) | 2022-09-16 |
| US20170059572A1 (en) | 2017-03-02 |
| US20180045728A1 (en) | 2018-02-15 |
| HRP20192131T1 (hr) | 2020-02-21 |
| EP3076949B1 (en) | 2019-09-04 |
| JP2017501694A (ja) | 2017-01-19 |
| AU2019201290A1 (en) | 2019-03-14 |
| JP2019198327A (ja) | 2019-11-21 |
| EP3076949A1 (en) | 2016-10-12 |
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