DK3049059T3 - Intranasal dhe formulering til behandlingen af hovedpine - Google Patents
Intranasal dhe formulering til behandlingen af hovedpine Download PDFInfo
- Publication number
- DK3049059T3 DK3049059T3 DK14830861.2T DK14830861T DK3049059T3 DK 3049059 T3 DK3049059 T3 DK 3049059T3 DK 14830861 T DK14830861 T DK 14830861T DK 3049059 T3 DK3049059 T3 DK 3049059T3
- Authority
- DK
- Denmark
- Prior art keywords
- headache
- treatment
- dhe formulation
- intranasal
- intranasal dhe
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Otolaryngology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361881947P | 2013-09-24 | 2013-09-24 | |
PCT/IB2014/002706 WO2015044782A2 (en) | 2013-09-24 | 2014-09-24 | Intranasal dhe for the treatment of headache |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3049059T3 true DK3049059T3 (da) | 2022-01-31 |
Family
ID=52424045
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK14830861.2T DK3049059T3 (da) | 2013-09-24 | 2014-09-24 | Intranasal dhe formulering til behandlingen af hovedpine |
Country Status (6)
Country | Link |
---|---|
US (5) | US20160228433A1 (da) |
EP (2) | EP3049059B1 (da) |
JP (2) | JP2016531850A (da) |
DK (1) | DK3049059T3 (da) |
ES (1) | ES2904570T3 (da) |
WO (1) | WO2015044782A2 (da) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009100383A2 (en) | 2008-02-07 | 2009-08-13 | University Of Washington | Circumferential aerosol device |
RU2728583C2 (ru) | 2011-03-03 | 2020-07-30 | Импел Ньюрофарма Инк. | Устройство для назальной доставки лекарственных средств |
RU2618084C2 (ru) | 2011-05-09 | 2017-05-02 | Импел Ньюрофарма Инк. | Наконечники для назальной доставки лекарственных средств |
US10537692B2 (en) | 2013-04-28 | 2020-01-21 | Impel Neuropharma, Inc. | Medical unit dose container |
CA2998182A1 (en) | 2015-09-10 | 2017-03-16 | Impel Neuropharma, Inc. | In-line nasal delivery device |
WO2018025089A2 (en) | 2016-08-05 | 2018-02-08 | Shin Nippon Biomedical Laboratories, Ltd. | Pharmaceutical compositions |
US20190000753A1 (en) * | 2017-07-02 | 2019-01-03 | Dr. Reddy's Laboratories Ltd. | Nasal dosage forms of dihydroergotamine |
US11571532B2 (en) | 2017-11-21 | 2023-02-07 | Impel Pharmaceuticals Inc. | Intranasal device with dip tube |
CA3081680A1 (en) | 2017-11-21 | 2019-05-31 | Impel Neuropharma, Inc. | Intranasal device with inlet interface |
EP3735244B1 (en) * | 2018-01-05 | 2022-11-23 | Impel Pharmaceuticals Inc. | Intranasal delivery of dihydroergotamine by precision olfactory device |
CA3087698A1 (en) | 2018-01-05 | 2019-07-11 | Impel Neuropharma, Inc. | Intranasal delivery of olanzapine by precision olfactory device |
KR20210034047A (ko) | 2018-07-19 | 2021-03-29 | 임펠 뉴로파마 인코포레이티드 | 파킨슨 병 치료를 위한 레보도파 및 도파 데카르복실라아제 저해제의 기도 전달 |
CA3122396A1 (en) * | 2018-12-11 | 2020-06-18 | Satsuma Pharmaceuticals, Inc. | Compositions, devices, and methods for treating or preventing headaches |
GB2581431A (en) * | 2018-12-11 | 2020-08-19 | Satsuma Pharmaceuticals Inc | Compositions, devices, and methods for treating or preventing headaches |
KR20210109007A (ko) | 2019-01-03 | 2021-09-03 | 임펠 뉴로파마 인코포레이티드 | 비강 약물 전달 장치 |
BR112021023049A8 (pt) | 2019-05-17 | 2022-10-18 | Impel Neuropharma Inc | Dispositivo de dispensação nasal de uso único |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5169849A (en) * | 1982-02-01 | 1992-12-08 | Sandoz Ltd. | Nasal pharmaceutical compositions |
JPS59163313A (ja) * | 1983-03-09 | 1984-09-14 | Teijin Ltd | 経鼻投与用ペプチドホルモン類組成物 |
ES2239369T3 (es) * | 1993-03-26 | 2005-09-16 | Franciscus Wilhelmus Henricus Maria Merkus | Composiciones farmaceuticas para administracion intranasal de dihidroergotamina. |
JP3197221B2 (ja) * | 1996-02-27 | 2001-08-13 | 帝人株式会社 | 吸収性が改善された粉末状経鼻投与組成物 |
EP1238661A1 (en) * | 1999-10-12 | 2002-09-11 | Kaken Pharmaceutical Co., Ltd. | Powdery inhalational preparations and process for producing the same |
TW553752B (en) * | 2001-06-20 | 2003-09-21 | Inhale Therapeutic Syst | Powder aerosolization apparatus and method |
JP4721212B2 (ja) * | 2001-07-05 | 2011-07-13 | 株式会社新日本科学 | インスリンの経鼻投与用組成物 |
FR2834212B1 (fr) * | 2001-12-27 | 2004-07-09 | Besins Int Belgique | Utilisation d'une poudre a liberation immediate dans des compositions pharmaceutiques et nutraceutiques |
JP4212019B2 (ja) * | 2002-01-09 | 2009-01-21 | Translational Research 株式会社 | 薬物の経鼻投与用組成物 |
GB0228826D0 (en) * | 2002-12-11 | 2003-01-15 | Okpala Joseph | Hair technology in creating particles with improved delivery capabilities |
WO2004073729A1 (ja) * | 2003-02-21 | 2004-09-02 | Translational Research Ltd. | 薬物の経鼻投与用組成物 |
GB0304636D0 (en) * | 2003-02-28 | 2003-04-02 | Britannia Pharmaceuticals Ltd | Pharmaceutical composition for nasal delivery |
US8673360B2 (en) * | 2004-08-10 | 2014-03-18 | Shin Nippon Biomedical Laboratories, Ltd. | Compositions that enable rapid-acting and highly absorptive intranasal administration |
WO2007019229A1 (en) * | 2005-08-05 | 2007-02-15 | 3M Innovative Properties Company | Compositions exhibiting improved flowability |
WO2007066646A1 (ja) * | 2005-12-06 | 2007-06-14 | Asahi Kasei Chemicals Corporation | 高速直接打錠による錠剤の製造方法 |
CN101668544B (zh) * | 2006-12-26 | 2013-04-24 | 株式会社新日本科学 | 经鼻投用制剂 |
JP2009076785A (ja) * | 2007-09-21 | 2009-04-09 | Panasonic Corp | 半導体装置の製造方法 |
EP2429495A4 (en) * | 2009-05-15 | 2014-01-22 | Shin Nippon Biomedical Lab Ltd | INTRANASAL PHARMACEUTICAL COMPOSITIONS WITH ENHANCED PHARMACOKINETICS |
US20110171141A1 (en) * | 2009-06-26 | 2011-07-14 | Kellerman Donald J | Administration of dihydroergotamine mesylate particles using a metered dose inhaler |
WO2011013003A2 (en) | 2009-07-31 | 2011-02-03 | Shin Nippon Biomedical Laboratories, Ltd. | Intranasal granisetron and nasal applicator |
EP2558120A4 (en) * | 2010-04-15 | 2013-08-28 | Shin Nippon Biomedical Lab Ltd | METHOD AND COMPOSITION FOR INTRANASAL ADMINISTRATION |
US20110318277A1 (en) * | 2010-06-25 | 2011-12-29 | APT Pharmaceuticals, Inc. University of Maryland, Baltimore | Tacrolimus compositions for aerosol administration |
RU2594244C2 (ru) | 2011-01-31 | 2016-08-10 | Син Ниппон Байомедикал Лэборэтэриз, Лтд. | Устройства для интраназальной доставки |
WO2013090278A2 (en) * | 2011-12-11 | 2013-06-20 | Recro Pharma, Inc. | Intranasal dexmedetomidine compositions and methods of use thereof |
-
2014
- 2014-09-24 EP EP14830861.2A patent/EP3049059B1/en active Active
- 2014-09-24 DK DK14830861.2T patent/DK3049059T3/da active
- 2014-09-24 WO PCT/IB2014/002706 patent/WO2015044782A2/en active Application Filing
- 2014-09-24 EP EP21205407.6A patent/EP4008307A1/en active Pending
- 2014-09-24 US US15/023,206 patent/US20160228433A1/en not_active Abandoned
- 2014-09-24 ES ES14830861T patent/ES2904570T3/es active Active
- 2014-09-24 JP JP2016516520A patent/JP2016531850A/ja active Pending
-
2019
- 2019-05-16 US US16/414,350 patent/US20190275036A1/en not_active Abandoned
- 2019-09-06 JP JP2019162995A patent/JP6902583B2/ja active Active
-
2020
- 2020-02-14 US US16/791,431 patent/US20200179379A1/en not_active Abandoned
-
2022
- 2022-06-07 US US17/834,583 patent/US20230000860A1/en active Pending
-
2023
- 2023-10-02 US US18/479,335 patent/US20240108619A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
EP3049059B1 (en) | 2021-11-03 |
US20200179379A1 (en) | 2020-06-11 |
ES2904570T3 (es) | 2022-04-05 |
JP6902583B2 (ja) | 2021-07-14 |
WO2015044782A3 (en) | 2015-06-11 |
EP3049059A2 (en) | 2016-08-03 |
WO2015044782A2 (en) | 2015-04-02 |
US20190275036A1 (en) | 2019-09-12 |
JP2020007342A (ja) | 2020-01-16 |
EP4008307A1 (en) | 2022-06-08 |
US20160228433A1 (en) | 2016-08-11 |
US20230000860A1 (en) | 2023-01-05 |
US20240108619A1 (en) | 2024-04-04 |
JP2016531850A (ja) | 2016-10-13 |
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