DK3036032T3 - Fremgangsmåde til fremstilling af koncentrater af fortrinsvis vandopløselige aktive stoffer - Google Patents

Fremgangsmåde til fremstilling af koncentrater af fortrinsvis vandopløselige aktive stoffer Download PDF

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Publication number
DK3036032T3
DK3036032T3 DK14789179.0T DK14789179T DK3036032T3 DK 3036032 T3 DK3036032 T3 DK 3036032T3 DK 14789179 T DK14789179 T DK 14789179T DK 3036032 T3 DK3036032 T3 DK 3036032T3
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DK
Denmark
Prior art keywords
solution
solvent
process according
organic solvent
acetamiprid
Prior art date
Application number
DK14789179.0T
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English (en)
Inventor
Andreas Mühlanger
Andreas Rauch
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Kwizda Agro Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Kwizda Agro Gmbh filed Critical Kwizda Agro Gmbh
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Publication of DK3036032T3 publication Critical patent/DK3036032T3/da

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02Making microcapsules or microballoons
    • B01J13/06Making microcapsules or microballoons by phase separation
    • B01J13/14Polymerisation; cross-linking
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/26Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests in coated particulate form
    • A01N25/28Microcapsules or nanocapsules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5026Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5015Organic compounds, e.g. fats, sugars
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Dentistry (AREA)
  • Zoology (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Paints Or Removers (AREA)
  • Polyurethanes Or Polyureas (AREA)

Claims (6)

1. Fremgangsmåde til fremstilling af koncentrater af vandopløselige aktive stoffer, hvor, i en vandfri proces under anvendelse af faste aktive stoffer som udgangsmateriale, krystallerne af et aktivt stof fordeles ensartet i et organisk opløsningsmiddel under tilsætning af et dispergeringsmiddel, viskositeten af den således tilvejebragte opløsning eventuelt indstilles med et egnet hjælpemiddel, og dertil den således tilvejebragte opløsning tilsættes en polymerdanner, eventuelt i et andet organisk opløsningsmiddel, hvor viskositeten enten af den opløsning, der skal tilsættes, eller af den tilvejebragte opløsning eventuelt indstilles ved at tilsætte et egnet hjælpemiddel, og der hældes et befugtningsmiddel med mindst to funktionelle grupper i et tredje organisk opløsningsmiddel tilbage i den tilvejebragte opløsning, hvor viskositeten af enten den opløsning, der skal tilsættes, eller af den tilvejebragte opløsning igen eventuelt indstilles ved at tilsætte et egnet hjælpemiddel, kendetegnet ved, at polymerdanneren er udvalgt fra gruppen omfattende lavviskøse poly-methylen-polyphenylisocyanater, fortrinsvis med et gennemsnitligt NCO-indhold på 25-35, særligt foretrukket 30-32 %, samt blandinger heraf, og be-fugtningsmidlet er en i det mindste bifunktionel krydsbinder for NCO-grupper og tilsættes i en i det mindste støkiometrisk mængde, hvor befugtningsmidlet er eller omfatter en ethanolamin, især triethanolamin (TEA).
2. Fremgangsmåde ifølge krav 1, kendetegnet ved, at det aktive stof er udvalgt fra gruppen omfattende biologisk effektive, insekticide, herbicide, fungicide, akaricide, algicide, mikrobicide, mikrobistatiske, rodenticide og antibiotisk effektive aktive stoffer, imprægneringsmidler, tiltrækningsstoffer, duftstoffer og generelt tiltrækkende eller frastødende virkende duft- eller smagsstoffer samt blandinger af sådanne aktive stoffer.
3. Fremgangsmåde ifølge krav 1 eller 2, kendetegnet ved, at dispergerings-midlet er et polyvinylpyrrolidonderivat.
4. Fremgangsmåde ifølge et af kravene 1 til 3, kendetegnet ved, at opløsningsmidlet eller opløsningsmidlerne er udvalgt fra gruppen omfattende estere af planteolier, især methylestere og ethylhexylestere af de mellemkædede mættede, i hvert fald mono- eller polyumættede fedtsyrer med 8 til 16 C-ato-mer uden reaktive hydroxylgrupper, terpenkulbrinter, især appelsinterpen, alifatiske og aromatiske kulbrinter, ethere og estere af naturlige og tekniske alifatiske og aromatiske alkoholer i forgrenet eller uforgrenet form og blandinger heraf.
5. Fremgangsmåde ifølge et af kravene 1 til 4, kendetegnet ved, at reaktionen finder sted ved mellem 10 og 80, fortrinsvis mellem 40 og 60 °C, hhv. ved en temperatur på mindst 1 °C, bedre mindst 5 °C, særligt foretrukket mere end 10 °C under flammetemperaturen af det pågældende anvendte organiske opløsningsmiddel eller/og en temperatur, ved hvilken det/de anvendte opløsningsmiddel/opløsningsmidler har et så lavt damptryk, at der ved reaktionsbetingelser ikke opstår eller sker nogen eksplosionsfarlig atmosfære.
6. Pulver eller granulat, omfattende coatede krystaller af et aktivt stof, der kan opnås i henhold til en fremgangsmåde ifølge et af kravene 1 til 5.
DK14789179.0T 2013-08-21 2014-08-21 Fremgangsmåde til fremstilling af koncentrater af fortrinsvis vandopløselige aktive stoffer DK3036032T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13181187.9A EP2839877A1 (de) 2013-08-21 2013-08-21 Verfahren zur Herstellung von Konzentraten von vorzugsweise wasserlöslichen Wirkstoffen
PCT/EP2014/067836 WO2015025001A1 (de) 2013-08-21 2014-08-21 Verfahren zur herstellung von konzentraten von vorzugsweise wasserlöslichen wirkstoffen

Publications (1)

Publication Number Publication Date
DK3036032T3 true DK3036032T3 (da) 2017-03-13

Family

ID=49028934

Family Applications (1)

Application Number Title Priority Date Filing Date
DK14789179.0T DK3036032T3 (da) 2013-08-21 2014-08-21 Fremgangsmåde til fremstilling af koncentrater af fortrinsvis vandopløselige aktive stoffer

Country Status (12)

Country Link
US (1) US9757705B2 (da)
EP (2) EP2839877A1 (da)
JP (1) JP6100973B2 (da)
CN (1) CN105636684B (da)
AU (1) AU2014310579B2 (da)
BR (1) BR112016003479B1 (da)
DK (1) DK3036032T3 (da)
ES (1) ES2617550T3 (da)
HU (1) HUE031952T2 (da)
IL (1) IL244168A (da)
PL (1) PL3036032T3 (da)
WO (1) WO2015025001A1 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110326629A (zh) * 2019-07-01 2019-10-15 河北上瑞生物科技有限公司 一种农用精油助剂及其制备方法和应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3571049B2 (ja) * 1994-11-16 2004-09-29 エフ エム シー コーポレーション クロマゾンの低揮発調合物
US5597780A (en) 1994-11-16 1997-01-28 Fmc Corporation Low volatility formulations of microencapsulated clomazone
US5911923A (en) 1996-07-01 1999-06-15 Microtek Laboratories, Inc. Method for microencapsulating water-soluble or water-dispersible or water-sensitive materials in an organic continuous phase
DE19646110A1 (de) * 1996-11-08 1998-05-14 Bayer Ag Mikrokapseln unter Verwendung von Iminooxadiazindion-Polyisocyanaten
WO2005056700A1 (en) * 2003-12-06 2005-06-23 Fujifilm Imaging Colorants Limited A process for preparing modified particulate solid materials and inks comprising the same
JP2005169248A (ja) 2003-12-11 2005-06-30 Daicel Chem Ind Ltd マイクロカプセル及びその製造方法
GB0329601D0 (en) * 2003-12-20 2004-01-28 Avecia Ltd Process
GB0427747D0 (en) * 2004-12-18 2005-01-19 Avecia Ltd Process
GB0704335D0 (en) * 2007-03-07 2007-04-11 Fujifilm Imaging Colorants Ltd Process for preparing an encapsulated particulate solid
DE102008026051A1 (de) * 2008-05-30 2009-12-03 Evonik Stockhausen Gmbh Haut- und Handreinigungsmittel
UA107670C2 (en) * 2009-08-07 2015-02-10 Dow Agrosciences Llc Meso-sized capsules useful for the delivery of agricultural chemicals
CN101781851B (zh) * 2010-02-05 2011-12-28 绍兴县荣利达纺织科技有限公司 聚氨酯抗菌柔软涂层剂及其制备方法
DE102010028826A1 (de) 2010-05-10 2011-11-10 Henkel Ag & Co. Kgaa Mikroverkapselung von Aktivstoffen duch Grenzflächenpolymerisation
CN102883802B (zh) * 2010-05-14 2015-07-01 富士胶片映像着色有限公司 分散体、制备分散体的方法和喷墨打印油墨
WO2012069805A1 (en) * 2010-11-25 2012-05-31 Fujifilm Imaging Colorants Limited Process, dispersion, ink and use

Also Published As

Publication number Publication date
JP6100973B2 (ja) 2017-03-22
PL3036032T3 (pl) 2017-06-30
ES2617550T3 (es) 2017-06-19
US9757705B2 (en) 2017-09-12
EP2839877A1 (de) 2015-02-25
CN105636684B (zh) 2017-10-20
EP3036032A1 (de) 2016-06-29
WO2015025001A1 (de) 2015-02-26
BR112016003479B1 (pt) 2020-08-18
IL244168A (en) 2016-11-30
US20160198715A1 (en) 2016-07-14
IL244168A0 (en) 2016-04-21
HUE031952T2 (en) 2017-08-28
JP2016532637A (ja) 2016-10-20
AU2014310579A1 (en) 2016-03-17
AU2014310579B2 (en) 2017-03-30
EP3036032B1 (de) 2016-12-07
CN105636684A (zh) 2016-06-01

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