DK3010535T3 - Toxoide peptider afledt fra fenol opløselige modulin, delta toxin, superantigener og fusioner deraf - Google Patents

Toxoide peptider afledt fra fenol opløselige modulin, delta toxin, superantigener og fusioner deraf Download PDF

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Publication number
DK3010535T3
DK3010535T3 DK14813512.2T DK14813512T DK3010535T3 DK 3010535 T3 DK3010535 T3 DK 3010535T3 DK 14813512 T DK14813512 T DK 14813512T DK 3010535 T3 DK3010535 T3 DK 3010535T3
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DK
Denmark
Prior art keywords
toxoide
superantigenes
phenole
fusions
peptides derived
Prior art date
Application number
DK14813512.2T
Other languages
Danish (da)
English (en)
Inventor
Mohammad Javad Aman
Rajan Prasad Adhikari
Sergey Shulenin
Frederick Wayne Holtsberg
Hatice Karauzum
Original Assignee
Integrated Biotherapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52105236&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3010535(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Integrated Biotherapeutics Inc filed Critical Integrated Biotherapeutics Inc
Application granted granted Critical
Publication of DK3010535T3 publication Critical patent/DK3010535T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/085—Staphylococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK14813512.2T 2013-06-19 2014-06-18 Toxoide peptider afledt fra fenol opløselige modulin, delta toxin, superantigener og fusioner deraf DK3010535T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361836959P 2013-06-19 2013-06-19
PCT/US2014/042999 WO2014205111A1 (en) 2013-06-19 2014-06-18 Toxoid peptides derived from phenol soluble modulin, delta toxin, superantigens, and fusions thereof

Publications (1)

Publication Number Publication Date
DK3010535T3 true DK3010535T3 (da) 2020-11-30

Family

ID=52105236

Family Applications (1)

Application Number Title Priority Date Filing Date
DK14813512.2T DK3010535T3 (da) 2013-06-19 2014-06-18 Toxoide peptider afledt fra fenol opløselige modulin, delta toxin, superantigener og fusioner deraf

Country Status (7)

Country Link
US (2) US9815872B2 (OSRAM)
EP (1) EP3010535B1 (OSRAM)
JP (1) JP6632974B2 (OSRAM)
CA (1) CA2916231C (OSRAM)
DK (1) DK3010535T3 (OSRAM)
PT (1) PT3010535T (OSRAM)
WO (1) WO2014205111A1 (OSRAM)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9815872B2 (en) 2013-06-19 2017-11-14 Integrated Biotherapeutics, Inc. Toxoid peptides derived from phenol soluble modulin, delta toxin, superantigens, and fusions thereof
EP3500288A4 (en) 2016-08-22 2020-05-27 Technion Research & Development Foundation Limited ANTIMICROBIAL PEPTIDES AND USES THEREOF
US20190271022A1 (en) * 2016-10-27 2019-09-05 Medimmune, Llc Signal Polypeptide For Improved Secretion Of Protein
CN107224575B (zh) * 2017-03-06 2018-11-09 浙江海隆生物科技有限公司 奶牛金黄色葡萄球菌乳房炎亚单位疫苗的组合物及其制备方法和应用
CA3069747A1 (en) 2017-07-27 2019-01-31 Mohammad Javad Aman Immunogenic composition comprising a fusion peptide derived from superantigen toxoids
CN115427433A (zh) 2020-12-18 2022-12-02 生物医学研究及生物制品公司 保护性葡萄球菌外毒素疫苗
US12370235B2 (en) 2021-03-04 2025-07-29 University Of Saskatchewan Synthetic, non-natural antimicrobial peptides inspired by Staphylococcus auricularis delta toxin
GR1010289B (el) * 2021-04-27 2022-08-29 Integrated Biotherapeutic Vaccines, Inc., Τοξοειδη πεπτιδια που προερχονται απο διαλυτη σε φαινολη μοδουλινη, τοξινη δελτα, υπεραντιγονα και συντηξεις αυτων
CN113234125B (zh) * 2021-05-10 2022-12-06 华东理工大学 自组装多肽、多肽水凝胶及其制备方法和用途
WO2023227563A1 (en) 2022-05-23 2023-11-30 Biomedizinische Forschung & Bio-Produkte AG Protective staphylococcal exotoxin vaccine
WO2023247747A1 (en) 2022-06-23 2023-12-28 Biomedizinische Forschung & Bio-Produkte AG Protective staphylococcal exotoxin vaccine

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US6593114B1 (en) * 1996-01-05 2003-07-15 Human Genome Sciences, Inc. Staphylococcus aureus polynucleotides and sequences
TW517061B (en) 1996-03-29 2003-01-11 Pharmacia & Amp Upjohn Ab Modified/chimeric superantigens and their use
US5874064A (en) 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
US6713284B2 (en) 1997-06-25 2004-03-30 The United States Of America As Represented By The Secretary Of The Army Bacterial superantigen vaccines
US7087235B2 (en) 1997-06-25 2006-08-08 The United States Of America As Represented By The Secretary Of The Army Fusion protein of streptococcal pyrogenic exotoxins
WO2000002522A2 (en) * 1998-07-10 2000-01-20 U.S. Medical Research Institute Of Infectious Diseases Anthrax vaccine
GB0118155D0 (en) 2001-07-25 2001-09-19 Lorantis Ltd Superantigen
JP5102487B2 (ja) * 2003-03-07 2012-12-19 ワイス・ホールディングズ・コーポレイション 院内感染に対する免疫化のための多糖ブドウ球菌表面付着因子キャリアタンパク質接合体
US20050008633A1 (en) 2003-05-19 2005-01-13 Advanced Inhalation Research Inc. Chemical and physical modulators of bioavailability of inhaled compositions
US7754225B2 (en) 2006-07-20 2010-07-13 Glaxosmithkline Biologicals S.A. Method of protecting against staphylococcal infection
WO2008154101A1 (en) * 2007-06-06 2008-12-18 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Psm peptides as vaccine targets against methicillin-resistant staphylococcus aureus
JP5658564B2 (ja) * 2007-08-31 2015-01-28 ザ・ユニバーシティ・オブ・シカゴＴｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｃｈｉｃａｇｏ ブドウ球菌肺疾患および状態に対する免疫に関連した方法および組成物
JP2014507142A (ja) * 2011-02-08 2014-03-27 インテグレイテッド バイオセラピューティクス，インコーポレイテッド α溶血素オリゴペプチドを含む免疫原性組成物
CN103561762A (zh) * 2011-03-16 2014-02-05 明尼苏达大学董事会 诱导针对葡萄球菌属中细菌的免疫应答的组合物和方法
DK2785368T3 (da) 2011-12-02 2019-05-27 Integrated Biotherapeutics Inc Immunogen sammensætning, der omfatter panton-valentine-leukocidin (pvl)-afledte polypeptider
US9815872B2 (en) 2013-06-19 2017-11-14 Integrated Biotherapeutics, Inc. Toxoid peptides derived from phenol soluble modulin, delta toxin, superantigens, and fusions thereof

Also Published As

Publication number Publication date
US10174085B2 (en) 2019-01-08
CA2916231A1 (en) 2014-12-24
EP3010535A1 (en) 2016-04-27
US9815872B2 (en) 2017-11-14
EP3010535B1 (en) 2019-08-14
CA2916231C (en) 2024-02-06
JP2016522259A (ja) 2016-07-28
US20160185829A1 (en) 2016-06-30
PT3010535T (pt) 2020-07-03
US20180148482A1 (en) 2018-05-31
JP6632974B2 (ja) 2020-01-22
WO2014205111A1 (en) 2014-12-24
EP3010535A4 (en) 2017-03-01

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