DK299584A - Hidtil ukendte prostacyklinderivater, fremgangsmaade til deres fremstilling og deres anvendelse som laegemidler - Google Patents

Hidtil ukendte prostacyklinderivater, fremgangsmaade til deres fremstilling og deres anvendelse som laegemidler Download PDF

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Publication number
DK299584A
DK299584A DK299584A DK299584A DK299584A DK 299584 A DK299584 A DK 299584A DK 299584 A DK299584 A DK 299584A DK 299584 A DK299584 A DK 299584A DK 299584 A DK299584 A DK 299584A
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DK
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Prior art keywords
group
medicines
unknown
procedures
preparation
Prior art date
Application number
DK299584A
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English (en)
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DK299584D0 (da
Inventor
Werner Skuballa
Helmut Dahl
Bernd Raduechel
Helmut Vorbrueggen
Olaf Loge
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of DK299584D0 publication Critical patent/DK299584D0/da
Publication of DK299584A publication Critical patent/DK299584A/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/41Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydrogenolysis or reduction of carboxylic groups or functional derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/02Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 2
    • C07D317/06Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 2 condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/30Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/041,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/061,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/06Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
DK299584A 1983-06-23 1984-06-19 Hidtil ukendte prostacyklinderivater, fremgangsmaade til deres fremstilling og deres anvendelse som laegemidler DK299584A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3322893A DE3322893A1 (de) 1983-06-23 1983-06-23 Neue prostacyclinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (2)

Publication Number Publication Date
DK299584D0 DK299584D0 (da) 1984-06-19
DK299584A true DK299584A (da) 1984-12-24

Family

ID=6202360

Family Applications (1)

Application Number Title Priority Date Filing Date
DK299584A DK299584A (da) 1983-06-23 1984-06-19 Hidtil ukendte prostacyklinderivater, fremgangsmaade til deres fremstilling og deres anvendelse som laegemidler

Country Status (20)

Country Link
US (1) US4894391A (da)
EP (1) EP0130142B1 (da)
JP (1) JPS6036477A (da)
AT (1) ATE43589T1 (da)
AU (1) AU562506B2 (da)
CA (1) CA1252088A (da)
CS (1) CS243491B2 (da)
DD (1) DD220204A5 (da)
DE (2) DE3322893A1 (da)
DK (1) DK299584A (da)
ES (1) ES533642A0 (da)
FI (1) FI82040C (da)
GR (1) GR82122B (da)
HU (1) HU191150B (da)
IL (1) IL72198A (da)
NO (1) NO158874C (da)
NZ (1) NZ208623A (da)
PH (1) PH22431A (da)
SU (1) SU1450739A3 (da)
ZA (1) ZA844766B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63174984A (ja) * 1987-01-16 1988-07-19 Nissan Chem Ind Ltd シアノプロスタサイクリン類の合成法
ATE122563T1 (de) * 1989-07-27 1995-06-15 Ueno Seiyaku Oyo Kenkyujo Kk Verwendung von 15-keto-prostansäure-derivaten zur herstellung eines medikaments für die verbesserung der ausscheidung des kaliumions.
CN1224354A (zh) * 1997-02-27 1999-07-28 东丽株式会社 肺循环改善剂
US7008307B2 (en) * 2003-09-02 2006-03-07 Wolff Industries Apparatus for sharpening a circular blade
US20080242713A1 (en) * 2007-03-28 2008-10-02 Bayer Schering Pharma Aktiengesellschaft Novel 5-cyano-prostacyclin derivatives as agents for the treatment of autoimmune diseases
EP1975163A1 (en) * 2007-03-28 2008-10-01 Bayer Schering Pharma Aktiengesellschaft Novel 5-cyano-prostacyclin derivatives and their use as agents for the treatment of influenza a viral infection
EP1988087A1 (en) * 2007-03-28 2008-11-05 Bayer Schering Pharma Aktiengesellschaft Novel 5-cyano-prostacyclin derivatives and their use as agents for the treatment of autoimmune diseases
US7776896B2 (en) * 2007-03-28 2010-08-17 Bayer Schering Pharma Aktiengesellschaft 5-cyano-prostacyclin derivatives as agents for the treatment of influenza a viral infection

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3953435A (en) * 1974-01-10 1976-04-27 Ono Pharmaceutical Company Aldehyde derivatives of prostaglandins
DE2753244A1 (de) * 1977-11-25 1979-06-07 Schering Ag Neue prostacyclinderivate und verfahren zu ihrer herstellung
US4565827A (en) * 1980-10-27 1986-01-21 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara R.T. 7-Substituted PGI2 -derivatives and pharmaceutical compositions containing them
DE3041601A1 (de) * 1980-10-31 1982-06-16 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue prostacyclinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US4475681A (en) * 1982-05-24 1984-10-09 The Micromanipulator Co., Inc. Bonder apparatus

Also Published As

Publication number Publication date
FI842524A0 (fi) 1984-06-21
IL72198A (en) 1987-09-16
CS474184A2 (en) 1985-08-15
IL72198A0 (en) 1984-10-31
NO158874C (no) 1988-11-09
CS243491B2 (en) 1986-06-12
DD220204A5 (de) 1985-03-27
DE3478435D1 (en) 1989-07-06
AU562506B2 (en) 1987-06-11
HUT34180A (en) 1985-02-28
ES8503348A1 (es) 1985-03-01
EP0130142B1 (de) 1989-05-31
US4894391A (en) 1990-01-16
NO158874B (no) 1988-08-01
NZ208623A (en) 1987-11-27
FI82040B (fi) 1990-09-28
ATE43589T1 (de) 1989-06-15
JPS6036477A (ja) 1985-02-25
FI82040C (fi) 1991-01-10
DK299584D0 (da) 1984-06-19
HU191150B (en) 1987-01-28
FI842524A (fi) 1984-12-24
GR82122B (da) 1984-12-13
ZA844766B (en) 1985-02-27
NO842534L (no) 1984-12-27
EP0130142A1 (de) 1985-01-02
ES533642A0 (es) 1985-03-01
CA1252088A (en) 1989-04-04
SU1450739A3 (ru) 1989-01-07
AU2978684A (en) 1985-01-03
PH22431A (en) 1988-09-12
DE3322893A1 (de) 1985-01-03

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