DK2954062T3 - Fremgangsmåde til fremstilling af fructose - Google Patents
Fremgangsmåde til fremstilling af fructose Download PDFInfo
- Publication number
- DK2954062T3 DK2954062T3 DK14703332.8T DK14703332T DK2954062T3 DK 2954062 T3 DK2954062 T3 DK 2954062T3 DK 14703332 T DK14703332 T DK 14703332T DK 2954062 T3 DK2954062 T3 DK 2954062T3
- Authority
- DK
- Denmark
- Prior art keywords
- fructose
- glucosone
- process according
- redox
- glucose
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/02—Monosaccharides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01307—D-Xylose reductase (1.1.1.307)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/03—Oxidoreductases acting on the CH-OH group of donors (1.1) with a oxygen as acceptor (1.1.3)
- C12Y101/0301—Pyranose oxidase (1.1.3.10)
-
- C—CHEMISTRY; METALLURGY
- C13—SUGAR INDUSTRY
- C13K—SACCHARIDES OBTAINED FROM NATURAL SOURCES OR BY HYDROLYSIS OF NATURALLY OCCURRING DISACCHARIDES, OLIGOSACCHARIDES OR POLYSACCHARIDES
- C13K11/00—Fructose
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Claims (11)
1. Fremgangsmåde til fremstilling af D-fructose ud fra D-glucose kendetegnet ved, at, i en one-pot-reaktion, a) D-glucose oxiderer enzymatisk til D-glucoson med en pyranose-2-oxidase, og b) D-glucoson reduceres enzymatisk til D-fructose med en reduktase, hvor der især i trin b) anvendes en redox-cofaktor.
2. Fremgangsmåde ifølge krav 1, kendetegnet ved, at fremgangsmåden foregår uden isolering af mellemprodukter.
3. Fremgangsmåde ifølge krav 1, kendetegnet ved, at forekommende FI2O2 fjernes ved hjælp af en katalase.
4. Fremgangsmåde ifølge et af kravene 1 til 3, kendetegnet ved, at der med henblik på reduktionen af D-glucoson til D-fructose anvendes en xylose-reduk-tase.
5. Fremgangsmåde ifølge et af kravene 1 til 4, kendetegnet ved, at der, især ved reduktionen af D-glucoson til D-fructose, anvendes redox-cofaktorer, især NAD(P)H, især, at enzymet, som anvendes i trin b), er NADP(H)-afhængigt.
6. Fremgangsmåde ifølge et af kravene 1 til 5, kendetegnet ved, at redox-cofaktorerne NAD(P)+ og/eller NAD(P)H tilsættes ved reaktionen af D-glucose til D-fructose.
7. Fremgangsmåde ifølge et af kravene 5 eller 6, kendetegnet ved, at anvendte redox-cofaktorer underkastes en genanvendelse, især ved hjælp af et egnet cofaktor-regenereringssystem.
8. Fremgangsmåde ifølge et af kravene 5 til 7, kendetegnet ved, at redox-cofaktoren regenereres ved anvendelsen af co-faktorerne NAD(P)H/NAD(P)+, især ved reduktionen af D-glucoson til D-fructose, under anvendelse af et co-substrat, især udvalgt blandt en alkohol, mælkesyre og dennes salte, pyro-druesyre og dennes salte, oxygen, hydrogen og/eller myresyre og dennes salte.
9. Fremgangsmåde ifølge et af kravene 5 til 8, hvor redox-cofaktoren regenereres ved hjælp af et redoxenzym, især ved hjælp af en alkoholdehydroge-nase.
10. Fremgangsmåde ifølge et af kravene 1 til 9, kendetegnet ved, at den afvikles i henhold til det følgende reaktionsskema 2
i hvilket LkADFI betegner en alkoholdehydrogenase, især en alkoholdehydro-genase fra Lactobacillus kefir, som er NADP(FI)-afhængig.
11. Fremgangsmåde ifølge et af kravene 1 til 10, kendetegnet ved, at den fremstillede D-fructose reageres yderligere til furanderivater.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ATA50091/2013A AT513928B1 (de) | 2013-02-06 | 2013-02-06 | Verfahren zur Herstellung von Fructose |
| PCT/EP2014/052230 WO2014122167A1 (de) | 2013-02-06 | 2014-02-05 | Verfahren zur herstellung von fructose |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2954062T3 true DK2954062T3 (da) | 2018-08-13 |
Family
ID=50070543
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK14703332.8T DK2954062T3 (da) | 2013-02-06 | 2014-02-05 | Fremgangsmåde til fremstilling af fructose |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US10113192B2 (da) |
| EP (1) | EP2954062B1 (da) |
| AT (1) | AT513928B1 (da) |
| AU (1) | AU2014214038B2 (da) |
| CA (1) | CA2900310C (da) |
| DK (1) | DK2954062T3 (da) |
| ES (1) | ES2683208T3 (da) |
| HR (1) | HRP20181223T1 (da) |
| HU (1) | HUE038656T2 (da) |
| PL (1) | PL2954062T3 (da) |
| RS (1) | RS57530B1 (da) |
| TR (1) | TR201810706T4 (da) |
| WO (1) | WO2014122167A1 (da) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107556345A (zh) * | 2017-08-24 | 2018-01-09 | 北京林业大学 | 一种酶催化结合化学催化制备果糖或甘露醇的方法 |
| EP3839054A1 (en) | 2019-12-20 | 2021-06-23 | Cascat GmbH | Production of fructose from oligo- and/or polysaccharides |
| EP4368720A1 (de) * | 2022-11-09 | 2024-05-15 | Annikki GmbH | Verfahren zur herstellung einer wässerigen lösung, welche glycerin enthält |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4246347A (en) * | 1979-05-29 | 1981-01-20 | Cetus Corporation | Process for the production of fructose |
| HU183630B (en) * | 1980-06-18 | 1984-05-28 | Standard Brands Inc | Process for preparing glucosone |
| US4321324A (en) | 1980-06-18 | 1982-03-23 | Standard Brands Incorporated | Process for making glucosone |
| US4442207A (en) * | 1982-06-30 | 1984-04-10 | Nabisco Brands, Inc. | Process for production of glucosone |
| US5225339A (en) * | 1992-02-26 | 1993-07-06 | The Scripps Research Institute | Lactobacillus kefir alcohol dehydrogenase |
| FR2792939B1 (fr) | 1999-04-27 | 2001-07-27 | Roquette Freres | Procede de preparation de fructose par hydrogenation de la glucosone |
| US7939681B2 (en) * | 2006-08-07 | 2011-05-10 | Battelle Memorial Institute | Methods for conversion of carbohydrates in ionic liquids to value-added chemicals |
| TW201343623A (zh) * | 2012-02-07 | 2013-11-01 | Annikki Gmbh | 使氧化還原輔因子經酶催化再生之方法 |
-
2013
- 2013-02-06 AT ATA50091/2013A patent/AT513928B1/de active
-
2014
- 2014-02-05 PL PL14703332T patent/PL2954062T3/pl unknown
- 2014-02-05 EP EP14703332.8A patent/EP2954062B1/de active Active
- 2014-02-05 AU AU2014214038A patent/AU2014214038B2/en active Active
- 2014-02-05 US US14/763,678 patent/US10113192B2/en active Active
- 2014-02-05 TR TR2018/10706T patent/TR201810706T4/tr unknown
- 2014-02-05 CA CA2900310A patent/CA2900310C/en active Active
- 2014-02-05 RS RS20180911A patent/RS57530B1/sr unknown
- 2014-02-05 WO PCT/EP2014/052230 patent/WO2014122167A1/de active Application Filing
- 2014-02-05 HU HUE14703332A patent/HUE038656T2/hu unknown
- 2014-02-05 ES ES14703332.8T patent/ES2683208T3/es active Active
- 2014-02-05 DK DK14703332.8T patent/DK2954062T3/da active
-
2018
- 2018-08-01 HR HRP20181223TT patent/HRP20181223T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AT513928A1 (de) | 2014-08-15 |
| RS57530B1 (sr) | 2018-10-31 |
| AU2014214038A1 (en) | 2015-08-20 |
| CA2900310C (en) | 2021-05-04 |
| WO2014122167A1 (de) | 2014-08-14 |
| AU2014214038B2 (en) | 2017-05-18 |
| AT513928B1 (de) | 2015-06-15 |
| ES2683208T3 (es) | 2018-09-25 |
| HRP20181223T1 (hr) | 2018-10-19 |
| US20150353978A1 (en) | 2015-12-10 |
| EP2954062B1 (de) | 2018-05-09 |
| HUE038656T2 (hu) | 2018-11-28 |
| CA2900310A1 (en) | 2014-08-14 |
| US10113192B2 (en) | 2018-10-30 |
| TR201810706T4 (tr) | 2018-08-27 |
| PL2954062T3 (pl) | 2018-10-31 |
| EP2954062A1 (de) | 2015-12-16 |
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