DK285683A - Fremgangsmaade til fremstilling af substituerede phenylpiperazinforbindelser - Google Patents
Fremgangsmaade til fremstilling af substituerede phenylpiperazinforbindelser Download PDFInfo
- Publication number
- DK285683A DK285683A DK285683A DK285683A DK285683A DK 285683 A DK285683 A DK 285683A DK 285683 A DK285683 A DK 285683A DK 285683 A DK285683 A DK 285683A DK 285683 A DK285683 A DK 285683A
- Authority
- DK
- Denmark
- Prior art keywords
- procedure
- preparation
- substituted phenylpiperazine
- phenylpiperazine compounds
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/391,198 US4452798A (en) | 1982-06-22 | 1982-06-22 | 1-Substituted phenyl-4-alkyl hydantoin piperazine compounds as antihypertensive agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK285683D0 DK285683D0 (da) | 1983-06-21 |
| DK285683A true DK285683A (da) | 1983-12-23 |
Family
ID=23545665
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK285683A DK285683A (da) | 1982-06-22 | 1983-06-21 | Fremgangsmaade til fremstilling af substituerede phenylpiperazinforbindelser |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4452798A (de) |
| EP (1) | EP0103357A3 (de) |
| JP (1) | JPS5925376A (de) |
| KR (1) | KR840005726A (de) |
| AU (1) | AU537383B2 (de) |
| CA (1) | CA1204754A (de) |
| DK (1) | DK285683A (de) |
| ES (2) | ES523462A0 (de) |
| FI (1) | FI832241L (de) |
| GR (1) | GR78313B (de) |
| HU (1) | HU187941B (de) |
| IL (1) | IL68942A (de) |
| NO (1) | NO832254L (de) |
| NZ (1) | NZ204658A (de) |
| PH (1) | PH18302A (de) |
| PT (1) | PT76899B (de) |
| ZA (1) | ZA834500B (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL114027A (en) | 1994-06-08 | 1999-11-30 | Lundbeck & Co As H | 4-Phenyl piperazine (piperidine or tetrahydropyridine) derivatives serotinin 5-HT1A and dopamin D2 receptor ligand pharmaceutical compositions containing them |
| US6083950A (en) * | 1997-11-13 | 2000-07-04 | Ranbaxy Laboratories Limited | 1-(4-arylpiperazin-1-yl)-ω-[n-(α,ω-dicarboximido)]-alka nes useful as uro-selective α1-adrenoceptor blockers |
| BR9912318A (pt) * | 1998-07-21 | 2001-05-02 | Ranbaxy Lab Ltd | Compostos de 1- (4-arilpiperazin-1-il) -w- [n- (ol, w -dicarboximido) ] alcanos de utilidade como bloqueadores uro-seletivos de 1 - adrenoceptor. |
| AU1979799A (en) * | 1998-07-21 | 2000-02-14 | Ranbaxy Laboratories Limited | Arylpiperazine derivatives useful as uro-selective alpha-1-adrenoceptor blockers |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2836595A (en) * | 1958-05-27 | Piperazine derivatives and process for | ||
| US3037024A (en) * | 1962-05-29 | Chjchj | ||
| FR1012751A (fr) * | 1949-01-24 | 1952-07-17 | Rhone Poulenc Sa | Nouveau dérivé de la pipérazine et de la quinoléïne et son procédé de préparation |
| ES291187A1 (es) * | 1963-04-04 | 1964-01-16 | American Cyanamid Co | Un procedimiento para preparar piperazinas sustituidas |
| DE1445547C3 (de) * | 1964-10-13 | 1975-04-30 | Basf Ag, 6700 Ludwigshafen | Verfahren zur Herstellung von 3-Amino-2,1-benzoisothiazolen |
| US3494932A (en) * | 1967-06-26 | 1970-02-10 | American Cyanamid Co | Aminoalkyl substituted aryl hydantoins |
| US3576808A (en) * | 1967-09-15 | 1971-04-27 | Miles Lab | N-4-phenyl-1-piperazinylalkyl-5-phenyl-oxazolidinones |
| BE788280A (fr) * | 1971-09-04 | 1973-02-28 | Pfizer | Nouvelles 1-(3-trifluoro-methyl-phenyl)-4-((amido cyclique)- alkyl) piperazines et composition pharmaceutique les contenant |
| US3806510A (en) * | 1972-09-18 | 1974-04-23 | Parke Davis & Co | 4(orthoalkylthio phenyl)piperazin-1-yl hydantoins |
| US4038279A (en) * | 1972-12-23 | 1977-07-26 | Boehringer Ingelheim Gmbh | N-aryl-n'-(phenyl-or phenoxy-alkyl)-piperazines and salts thereof |
| DE2263211A1 (de) * | 1972-12-23 | 1974-07-04 | Boehringer Sohn Ingelheim | Neue arylpiperazine und verfahren zu ihrer herstellung |
| GB1443598A (en) * | 1973-07-06 | 1976-07-21 | Acraf | 1- 3-acetylaminopropyl-4-2,5-dichlorophenyl-piperazine |
| US3892748A (en) * | 1973-07-20 | 1975-07-01 | Miles Lab | 5,5-Diphenyl-3-(piperidino, tetrahydropyridyl-1-and piperazino)-hydantoins |
| US3879395A (en) * | 1973-10-23 | 1975-04-22 | Parke Davis & Co | 3-(1-Piperazinylalkylamino)-2-cycloalken-1-one compounds and methods for their production |
| FR2306694A1 (fr) * | 1975-04-07 | 1976-11-05 | Parcor | Derives de la piperazine |
| BE503170A (de) * | 1975-09-02 |
-
1982
- 1982-06-22 US US06/391,198 patent/US4452798A/en not_active Expired - Fee Related
-
1983
- 1983-06-06 CA CA000429731A patent/CA1204754A/en not_active Expired
- 1983-06-09 IL IL68942A patent/IL68942A/xx unknown
- 1983-06-09 AU AU15658/83A patent/AU537383B2/en not_active Ceased
- 1983-06-17 EP EP83303506A patent/EP0103357A3/de not_active Withdrawn
- 1983-06-20 PT PT76899A patent/PT76899B/pt unknown
- 1983-06-20 FI FI832241A patent/FI832241L/fi not_active Application Discontinuation
- 1983-06-20 GR GR71726A patent/GR78313B/el unknown
- 1983-06-20 ZA ZA834500A patent/ZA834500B/xx unknown
- 1983-06-21 DK DK285683A patent/DK285683A/da not_active Application Discontinuation
- 1983-06-21 JP JP58110310A patent/JPS5925376A/ja active Pending
- 1983-06-21 NZ NZ204658A patent/NZ204658A/en unknown
- 1983-06-21 HU HU832202A patent/HU187941B/hu unknown
- 1983-06-21 NO NO832254A patent/NO832254L/no unknown
- 1983-06-21 ES ES523462A patent/ES523462A0/es active Granted
- 1983-06-21 PH PH29094A patent/PH18302A/en unknown
- 1983-06-21 KR KR1019830002796A patent/KR840005726A/ko not_active IP Right Cessation
-
1984
- 1984-11-26 ES ES537961A patent/ES8601948A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DK285683D0 (da) | 1983-06-21 |
| ZA834500B (en) | 1984-03-28 |
| KR840005726A (ko) | 1984-11-16 |
| NO832254L (no) | 1983-12-23 |
| FI832241L (fi) | 1983-12-23 |
| NZ204658A (en) | 1985-12-13 |
| IL68942A0 (en) | 1983-10-31 |
| GR78313B (de) | 1984-09-26 |
| PH18302A (en) | 1985-05-29 |
| AU1565883A (en) | 1984-01-05 |
| US4452798A (en) | 1984-06-05 |
| EP0103357A2 (de) | 1984-03-21 |
| HU187941B (en) | 1986-03-28 |
| ES537961A0 (es) | 1985-11-01 |
| FI832241A0 (fi) | 1983-06-20 |
| ES8504776A1 (es) | 1985-04-16 |
| ES8601948A1 (es) | 1985-11-01 |
| IL68942A (en) | 1987-02-27 |
| ES523462A0 (es) | 1985-04-16 |
| EP0103357A3 (de) | 1986-01-08 |
| PT76899B (en) | 1986-01-24 |
| AU537383B2 (en) | 1984-06-21 |
| PT76899A (en) | 1983-07-01 |
| CA1204754A (en) | 1986-05-20 |
| JPS5925376A (ja) | 1984-02-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |