DK282076A - Fremgangsmade til fremstilling af 2,3-dihydro6,7-disubstitueret-5-acyl-benzofuran-2-carboxylsyrer - Google Patents
Fremgangsmade til fremstilling af 2,3-dihydro6,7-disubstitueret-5-acyl-benzofuran-2-carboxylsyrerInfo
- Publication number
- DK282076A DK282076A DK282076A DK282076A DK282076A DK 282076 A DK282076 A DK 282076A DK 282076 A DK282076 A DK 282076A DK 282076 A DK282076 A DK 282076A DK 282076 A DK282076 A DK 282076A
- Authority
- DK
- Denmark
- Prior art keywords
- dihydro6
- benzofuran
- disubstituted
- acyl
- procedure
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/80—Radicals substituted by oxygen atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US59483975A | 1975-07-09 | 1975-07-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK282076A true DK282076A (da) | 1977-01-10 |
Family
ID=24380621
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK282076A DK282076A (da) | 1975-07-09 | 1976-06-23 | Fremgangsmade til fremstilling af 2,3-dihydro6,7-disubstitueret-5-acyl-benzofuran-2-carboxylsyrer |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US4087542A (ru) |
| JP (1) | JPS5210261A (ru) |
| AU (1) | AU505135B2 (ru) |
| BE (1) | BE843644A (ru) |
| CH (1) | CH624949A5 (ru) |
| DE (1) | DE2630800A1 (ru) |
| DK (1) | DK282076A (ru) |
| ES (1) | ES449389A1 (ru) |
| FR (1) | FR2316934A1 (ru) |
| GB (1) | GB1511427A (ru) |
| HU (1) | HU176564B (ru) |
| NL (1) | NL7606908A (ru) |
| SE (1) | SE7607157L (ru) |
| ZA (1) | ZA764080B (ru) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4100294A (en) * | 1976-12-06 | 1978-07-11 | Merck & Co., Inc. | 5-(Hydroxy (substituted) methyl)-2,3-dihydrobenzo furan-2-carboxylic acid and its derivatives |
| US4205080A (en) * | 1977-07-21 | 1980-05-27 | Shell Oil Company | 2,3-Dihydro benzofuran carboxamides |
| US4189496A (en) * | 1978-02-16 | 1980-02-19 | Merck & Co., Inc. | 2,3-Dihydro-5-thienylmethyl and furylmethyl-6-substituted and 6,7-disubstituted-benzofuran-2-carboxylic acid |
| EP0019955A1 (en) * | 1979-05-16 | 1980-12-10 | Shell Internationale Researchmaatschappij B.V. | Benzofurancarboxylic acid derivatives, their preparation and their inclusion in lipogenesis inhibiting compositions |
| US4237130A (en) * | 1979-06-21 | 1980-12-02 | Merck & Co., Inc. | 2,3-Dihydro-6,7-disubstituted-5-(substituted sulfonyl)benzofuran-2-carboxylic acids |
| US4237144A (en) * | 1979-06-21 | 1980-12-02 | Merck & Co., Inc. | 2,3-Dihydro-2,6,7-trisubstituted-5-acylbenzofurans |
| JPS5737737A (en) * | 1980-08-15 | 1982-03-02 | Fuji Photo Film Co Ltd | Magnetic recording medium |
| NZ200641A (en) * | 1981-07-13 | 1985-12-13 | Merck & Co Inc | Pharmaceutical compositions containing(+)and(-)enantiomers of indacrinone |
| US4510322A (en) * | 1981-07-13 | 1985-04-09 | Merck & Co., Inc. | Indacrinone having enhanced uricosuric |
| US4435422A (en) * | 1982-09-15 | 1984-03-06 | Abbott Laboratories | 5-Substituted 2,3-dihydrobenzofuran-2-carboxylic acids and their use in diuretic compositions |
| JPS5973579A (ja) * | 1982-10-19 | 1984-04-25 | Kotobuki Seiyaku Kk | ベンゾフラン又はベンゾチオフェン誘導体，この化合物を有効成分とする尿酸排泄剤及びその製造方法 |
| DE3460315D1 (en) * | 1983-02-19 | 1986-08-28 | Beecham Group Plc | Benzofuran and benzothiophene-carboxylic-acid derivatives |
| US4578509A (en) * | 1983-04-01 | 1986-03-25 | Merck & Co., Inc. | Process for preparing a manipulated enantiomer mixture by asymmetric chiral phase transfer catalysis |
| DE3317884A1 (de) * | 1983-05-17 | 1984-11-22 | Hoechst Ag, 6230 Frankfurt | 5-(4-chlor-3-sulfamoylbenzoyl)-2,3-dihydro-2-benzofurancarbonsaeuren und verfahren zu ihrer herstellung |
| US4654365A (en) * | 1985-09-26 | 1987-03-31 | Merck & Co., Inc. | 2,3-dihydro-5-(3-oxo-2-cyclohexen-1-yl)-2-benzofurancarboxylic acids, and their salts useful in the treatment of brain injury |
| US6858614B2 (en) * | 2002-02-19 | 2005-02-22 | Parion Sciences, Inc. | Phenolic guanidine sodium channel blockers |
| US6858615B2 (en) | 2002-02-19 | 2005-02-22 | Parion Sciences, Inc. | Phenyl guanidine sodium channel blockers |
| US6903105B2 (en) * | 2003-02-19 | 2005-06-07 | Parion Sciences, Inc. | Sodium channel blockers |
| US20050090505A1 (en) * | 2003-08-18 | 2005-04-28 | Johnson Michael R. | Methods of reducing risk of infection from pathogens |
| US7745442B2 (en) | 2003-08-20 | 2010-06-29 | Parion Sciences, Inc. | Methods of reducing risk of infection from pathogens |
| AR086745A1 (es) | 2011-06-27 | 2014-01-22 | Parion Sciences Inc | 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida |
| AU2013363215B2 (en) | 2012-12-17 | 2018-03-01 | Parion Sciences, Inc. | 3,5-diamino-6-chloro-N-(N-(4-phenylbutyl)carbamimidoyl) pyrazine-2- carboxamide compounds |
| EP3150585A1 (en) | 2012-12-17 | 2017-04-05 | Parion Sciences, Inc. | Chloro-pyrazine carboxamide derivatives with epithelial sodium channel blocking activity |
| US9102633B2 (en) | 2013-12-13 | 2015-08-11 | Parion Sciences, Inc. | Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH508615A (de) * | 1968-05-30 | 1971-06-15 | Ciba Geigy Ag | Verfahren zur Herstellung von neuen heterocyclischen Carbonsäuren |
| FR2201883B1 (ru) * | 1972-10-05 | 1975-10-31 | Roussel Uclaf |
-
1976
- 1976-04-20 US US05/678,529 patent/US4087542A/en not_active Expired - Lifetime
- 1976-06-22 SE SE7607157A patent/SE7607157L/xx not_active Application Discontinuation
- 1976-06-23 DK DK282076A patent/DK282076A/da unknown
- 1976-06-24 NL NL7606908A patent/NL7606908A/xx not_active Application Discontinuation
- 1976-06-29 AU AU15404/76A patent/AU505135B2/en not_active Expired
- 1976-06-30 BE BE168519A patent/BE843644A/xx unknown
- 1976-06-30 ES ES449389A patent/ES449389A1/es not_active Expired
- 1976-07-06 GB GB28088/76A patent/GB1511427A/en not_active Expired
- 1976-07-06 CH CH865776A patent/CH624949A5/de not_active IP Right Cessation
- 1976-07-07 FR FR7620735A patent/FR2316934A1/fr active Granted
- 1976-07-08 DE DE19762630800 patent/DE2630800A1/de not_active Withdrawn
- 1976-07-08 ZA ZA00764080A patent/ZA764080B/xx unknown
- 1976-07-09 JP JP51081104A patent/JPS5210261A/ja active Pending
- 1976-07-09 HU HU76ME2002A patent/HU176564B/hu unknown
-
1978
- 1978-01-27 US US05/873,023 patent/US4163794A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CH624949A5 (ru) | 1981-08-31 |
| JPS5210261A (en) | 1977-01-26 |
| DE2630800A1 (de) | 1977-01-27 |
| ES449389A1 (es) | 1977-12-16 |
| AU1540476A (en) | 1978-01-05 |
| BE843644A (fr) | 1976-12-30 |
| FR2316934A1 (fr) | 1977-02-04 |
| US4087542A (en) | 1978-05-02 |
| GB1511427A (en) | 1978-05-17 |
| SE7607157L (sv) | 1977-01-10 |
| US4163794A (en) | 1979-08-07 |
| NL7606908A (nl) | 1977-01-11 |
| HU176564B (en) | 1981-03-28 |
| AU505135B2 (en) | 1979-11-08 |
| ZA764080B (en) | 1978-02-22 |
| FR2316934B1 (ru) | 1979-07-20 |
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