BE843644A - Acides 2,3-dihydro-6,7-disubstitue-5-(acyl)benzofuran-2-carboxyliques - Google Patents

Acides 2,3-dihydro-6,7-disubstitue-5-(acyl)benzofuran-2-carboxyliques

Info

Publication number
BE843644A
BE843644A BE168519A BE168519A BE843644A BE 843644 A BE843644 A BE 843644A BE 168519 A BE168519 A BE 168519A BE 168519 A BE168519 A BE 168519A BE 843644 A BE843644 A BE 843644A
Authority
BE
Belgium
Prior art keywords
disubstitute
benzofuran
dihydro
acyl
carboxylic acids
Prior art date
Application number
BE168519A
Other languages
English (en)
French (fr)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE843644A publication Critical patent/BE843644A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80—Radicals substituted by oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
BE168519A 1975-07-09 1976-06-30 Acides 2,3-dihydro-6,7-disubstitue-5-(acyl)benzofuran-2-carboxyliques BE843644A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59483975A 1975-07-09 1975-07-09

Publications (1)

Publication Number Publication Date
BE843644A true BE843644A (fr) 1976-12-30

Family

ID=24380621

Family Applications (1)

Application Number Title Priority Date Filing Date
BE168519A BE843644A (fr) 1975-07-09 1976-06-30 Acides 2,3-dihydro-6,7-disubstitue-5-(acyl)benzofuran-2-carboxyliques

Country Status (14)

Country Link
US (2) US4087542A (xx)
JP (1) JPS5210261A (xx)
AU (1) AU505135B2 (xx)
BE (1) BE843644A (xx)
CH (1) CH624949A5 (xx)
DE (1) DE2630800A1 (xx)
DK (1) DK282076A (xx)
ES (1) ES449389A1 (xx)
FR (1) FR2316934A1 (xx)
GB (1) GB1511427A (xx)
HU (1) HU176564B (xx)
NL (1) NL7606908A (xx)
SE (1) SE7607157L (xx)
ZA (1) ZA764080B (xx)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4100294A (en) 1976-12-06 1978-07-11 Merck & Co., Inc. 5-(Hydroxy (substituted) methyl)-2,3-dihydrobenzo furan-2-carboxylic acid and its derivatives
US4205080A (en) * 1977-07-21 1980-05-27 Shell Oil Company 2,3-Dihydro benzofuran carboxamides
US4189496A (en) * 1978-02-16 1980-02-19 Merck & Co., Inc. 2,3-Dihydro-5-thienylmethyl and furylmethyl-6-substituted and 6,7-disubstituted-benzofuran-2-carboxylic acid
EP0019955A1 (en) * 1979-05-16 1980-12-10 Shell Internationale Researchmaatschappij B.V. Benzofurancarboxylic acid derivatives, their preparation and their inclusion in lipogenesis inhibiting compositions
US4237144A (en) * 1979-06-21 1980-12-02 Merck & Co., Inc. 2,3-Dihydro-2,6,7-trisubstituted-5-acylbenzofurans
US4237130A (en) * 1979-06-21 1980-12-02 Merck & Co., Inc. 2,3-Dihydro-6,7-disubstituted-5-(substituted sulfonyl)benzofuran-2-carboxylic acids
JPS5737737A (en) * 1980-08-15 1982-03-02 Fuji Photo Film Co Ltd Magnetic recording medium
US4510322A (en) * 1981-07-13 1985-04-09 Merck & Co., Inc. Indacrinone having enhanced uricosuric
NZ200641A (en) * 1981-07-13 1985-12-13 Merck & Co Inc Pharmaceutical compositions containing(+)and(-)enantiomers of indacrinone
US4435422A (en) * 1982-09-15 1984-03-06 Abbott Laboratories 5-Substituted 2,3-dihydrobenzofuran-2-carboxylic acids and their use in diuretic compositions
JPS5973579A (ja) * 1982-10-19 1984-04-25 Kotobuki Seiyaku Kk ベンゾフラン又はベンゾチオフェン誘導体，この化合物を有効成分とする尿酸排泄剤及びその製造方法
DE3460315D1 (en) * 1983-02-19 1986-08-28 Beecham Group Plc Benzofuran and benzothiophene-carboxylic-acid derivatives
US4578509A (en) * 1983-04-01 1986-03-25 Merck & Co., Inc. Process for preparing a manipulated enantiomer mixture by asymmetric chiral phase transfer catalysis
DE3317884A1 (de) * 1983-05-17 1984-11-22 Hoechst Ag, 6230 Frankfurt 5-(4-chlor-3-sulfamoylbenzoyl)-2,3-dihydro-2-benzofurancarbonsaeuren und verfahren zu ihrer herstellung
US4654365A (en) * 1985-09-26 1987-03-31 Merck & Co., Inc. 2,3-dihydro-5-(3-oxo-2-cyclohexen-1-yl)-2-benzofurancarboxylic acids, and their salts useful in the treatment of brain injury
US6858615B2 (en) * 2002-02-19 2005-02-22 Parion Sciences, Inc. Phenyl guanidine sodium channel blockers
US6858614B2 (en) * 2002-02-19 2005-02-22 Parion Sciences, Inc. Phenolic guanidine sodium channel blockers
US6903105B2 (en) * 2003-02-19 2005-06-07 Parion Sciences, Inc. Sodium channel blockers
US20050090505A1 (en) * 2003-08-18 2005-04-28 Johnson Michael R. Methods of reducing risk of infection from pathogens
US7745442B2 (en) 2003-08-20 2010-06-29 Parion Sciences, Inc. Methods of reducing risk of infection from pathogens
AR086745A1 (es) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
KR20150095870A (ko) 2012-12-17 2015-08-21 패리온 사이언스 인코퍼레이티드 3,5-디아미노-6-클로로-n-(n-(4-페닐부틸)카르밤이미도일)피라진-2-카르복스아미드 화합물
AU2013363218B2 (en) 2012-12-17 2018-03-15 Parion Sciences, Inc. Chloro-pyrazine carboxamide derivatives useful for the treatment of diseases favoured by insufficient mucosal hydration
US9102633B2 (en) 2013-12-13 2015-08-11 Parion Sciences, Inc. Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH508615A (de) * 1968-05-30 1971-06-15 Ciba Geigy Ag Verfahren zur Herstellung von neuen heterocyclischen Carbonsäuren
FR2201883B1 (xx) * 1972-10-05 1975-10-31 Roussel Uclaf

Also Published As

Publication number Publication date
US4087542A (en) 1978-05-02
US4163794A (en) 1979-08-07
GB1511427A (en) 1978-05-17
ZA764080B (en) 1978-02-22
DK282076A (da) 1977-01-10
JPS5210261A (en) 1977-01-26
ES449389A1 (es) 1977-12-16
NL7606908A (nl) 1977-01-11
AU1540476A (en) 1978-01-05
AU505135B2 (en) 1979-11-08
FR2316934B1 (xx) 1979-07-20
FR2316934A1 (fr) 1977-02-04
SE7607157L (sv) 1977-01-10
CH624949A5 (xx) 1981-08-31
HU176564B (en) 1981-03-28
DE2630800A1 (de) 1977-01-27

Similar Documents

Publication Publication Date Title
FR2316934A1 (fr) Acides 2,3-dihydro-6,7-disubstitue-5-(acyl)benzofuran-2-carboxyliques
BE844649A (fr) Acides 1-hydroxy-3-aminoalcane-1,1-diphosphoniques
FR2345430A1 (fr) Nouveaux acides acetohydroxamiques
FR2306341A1 (fr) Culasse monocylindre
FR2296423A1 (fr) Nouveaux acides d 2,3-1,4-morpholino
FR2304346A1 (fr) Derives de salicylanilide
DK186776A (da) N-arylantranilsyrer
IT1058646B (it) Generatore di caratteri per la produzione di caratteri
FR2301246A1 (fr) Acides 6-oxo 7,7-disubstitues-6h-indeno
SE7604095L (sv) 4,4-dihydrospiro-2h-1,3-bensoxaziner
FR2332747A1 (fr) Derives d'a-aminocetones
SE7609769L (sv) 1,2-bensisoxazolderivat
FR2322604A1 (fr) Derives 3-triazolylthio d'ureido-7a-methoxy-ou demethoxycephalosporines
FR2297628A1 (fr) 2,3-dihydroergolines
SE7608452L (sv) 2,4-diamino-5-benzylpyrimidiner
BE837561A (fr) Preparation d'acides 6,11-dihydro-11-oxodibenzo (b,e) oxepine alcanoiques
BE832229A (fr) Acides 19, 20-bis-nor-prostanoiques hypolipemiants
BE828980A (fr) Acides 2,3-polymethylene-5-sulfamoylbenzoiques
BE846657A (fr) 2,4,6-triiodo-anilides 3,5-disubstitues d'acides polyhydroxy-monobasiques
SE7610219L (sv) Nya dibenso /b,e//1,4/ diazepiner
JPS5199309A (ja) Dendosofuki
IT1062420B (it) Perfluorovinileteri
BE828000A (fr) Acides 1,4-bis-formyl-cyclohexane-polycarboxyliques
FR2322843A1 (fr) Preparation de la 6, 10, 14-trimethylpentadeca-2-one
FR2303547A1 (fr) Derives de l'isoquinoleine