DK279890A - Liposom-indkapslede vincaalkaloider og anvendelse heraf til fremstilling af et laegemiddel til bekaempelse af tumorer - Google Patents

Liposom-indkapslede vincaalkaloider og anvendelse heraf til fremstilling af et laegemiddel til bekaempelse af tumorer Download PDF

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Publication number
DK279890A
DK279890A DK279890A DK279890A DK279890A DK 279890 A DK279890 A DK 279890A DK 279890 A DK279890 A DK 279890A DK 279890 A DK279890 A DK 279890A DK 279890 A DK279890 A DK 279890A
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DK
Denmark
Prior art keywords
caloids
vincal
liposom
encouraged
medicine
Prior art date
Application number
DK279890A
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English (en)
Other versions
DK279890D0 (da
DK175869B1 (da
Inventor
Aquilur Rahman
Original Assignee
Univ Georgetown
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Georgetown filed Critical Univ Georgetown
Publication of DK279890D0 publication Critical patent/DK279890D0/da
Publication of DK279890A publication Critical patent/DK279890A/da
Application granted granted Critical
Publication of DK175869B1 publication Critical patent/DK175869B1/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/475Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984Microcapsule with fluid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK199002798A 1988-05-23 1990-11-23 Liposom-indkapslede vincaalkaloider og anvendelse heraf til fremstilling af et lægemiddel til bekæmpelse af tumorer DK175869B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US07/197,648 US4952408A (en) 1988-05-23 1988-05-23 Liposome-encapsulated vinca alkaloids and their use in combatting tumors
US19764888 1988-05-23
US8902173 1989-05-23
PCT/US1989/002173 WO1989011292A1 (en) 1988-05-23 1989-05-23 Liposome-encapsulated vinca alkoaloids and their use in combatting tumors

Publications (3)

Publication Number Publication Date
DK279890D0 DK279890D0 (da) 1990-11-23
DK279890A true DK279890A (da) 1990-11-23
DK175869B1 DK175869B1 (da) 2005-04-25

Family

ID=22730210

Family Applications (1)

Application Number Title Priority Date Filing Date
DK199002798A DK175869B1 (da) 1988-05-23 1990-11-23 Liposom-indkapslede vincaalkaloider og anvendelse heraf til fremstilling af et lægemiddel til bekæmpelse af tumorer

Country Status (9)

Country Link
US (1) US4952408A (da)
EP (1) EP0416014B1 (da)
JP (1) JPH03504381A (da)
AU (1) AU625308B2 (da)
CA (1) CA1339077C (da)
DE (1) DE68914154T2 (da)
DK (1) DK175869B1 (da)
IE (1) IE64513B1 (da)
WO (1) WO1989011292A1 (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT706373E (pt) * 1992-03-23 2000-11-30 Univ Georgetown Taxol encapsulado num liposoma e um metodo
GB9211659D0 (en) * 1992-06-02 1992-07-15 Indena Spa New alkaloid derivatives,their use and pharmaceutical formulations containing them
US5595756A (en) * 1993-12-22 1997-01-21 Inex Pharmaceuticals Corporation Liposomal compositions for enhanced retention of bioactive agents
US5741516A (en) * 1994-06-20 1998-04-21 Inex Pharmaceuticals Corporation Sphingosomes for enhanced drug delivery
US6107102A (en) * 1995-06-07 2000-08-22 Regents Of The University Of California Therapeutic microdevices and methods of making and using same
US6447800B2 (en) 1996-01-18 2002-09-10 The University Of British Columbia Method of loading preformed liposomes using ethanol
US7314637B1 (en) 1999-06-29 2008-01-01 Neopharm, Inc. Method of administering liposomal encapsulated taxane
US6723338B1 (en) * 1999-04-01 2004-04-20 Inex Pharmaceuticals Corporation Compositions and methods for treating lymphoma
US7311924B2 (en) * 1999-04-01 2007-12-25 Hana Biosciences, Inc. Compositions and methods for treating cancer
DK1169021T3 (da) * 1999-04-01 2010-01-11 Hana Biosciences Inc Sammensætninger og fremgangsmåder til behandling af lymfom
US7244450B2 (en) * 1999-04-01 2007-07-17 Inex Pharmaceuticals Corporation Compositions and methods for treating lymphoma
EP2289549A3 (en) 1999-10-01 2011-06-15 Immunogen, Inc. Immunoconjugates for treating cancer
ATE413164T1 (de) 2000-11-09 2008-11-15 Neopharm Inc Sn-38-lipidkomplexe und verfahren zu ihrer verwendung
WO2002089772A1 (en) * 2001-05-09 2002-11-14 Inex Pharmaceuticals Corporation Anti-angiogenic therapy using liposome-encapsulated chemotherapeutic agents
WO2003030864A1 (en) * 2001-05-29 2003-04-17 Neopharm, Inc. Liposomal formulation of irinotecan
WO2003018018A2 (en) * 2001-08-24 2003-03-06 Neopharm, Inc. Vinorelbine compositions and methods of use
US20060030578A1 (en) * 2002-08-20 2006-02-09 Neopharm, Inc. Pharmaceutically active lipid based formulation of irinotecan
AU2003296897A1 (en) * 2002-08-20 2004-05-04 Neopharm, Inc. Pharmaceutical formulations of camptothecine derivatives
AU2003268087A1 (en) * 2002-08-23 2004-03-11 Ian Ma Liposomal gemcitabine compositions for better drug delivery
MXPA05008284A (es) * 2003-02-03 2006-03-21 Neopharm Inc Taxano y otros farmacos antineoplasicos encapsulados, liposomicos, estables, susceptibles de esterilizacion por filtracion.
US20060165744A1 (en) * 2003-05-22 2006-07-27 Neopharm, Inc Combination liposomal formulations
CA2584279C (en) * 2004-11-05 2015-01-27 Index Pharmaceuticals Corporation Compositions and methods for stabilizing liposomal drug formulations
KR100651728B1 (ko) * 2004-11-10 2006-12-06 한국전자통신연구원 정착기를 갖는 전자 소자용 화합물 및 이를 포함하는 전자소자와 이들의 제조 방법
WO2009059449A1 (en) * 2007-11-05 2009-05-14 Celsion Corporation Novel thermosensitive liposomes containing therapeutic agents
RU2655964C2 (ru) 2012-11-20 2018-05-30 Спектрум Фармасьютикалз, Инк. Улучшенный способ получения инкапсулированного в липосомы винкристина для терапевтического применения
TWI678213B (zh) 2015-07-22 2019-12-01 美商史倍壯製藥公司 用於長春新鹼硫酸鹽脂質體注射之即可使用的調配物

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4479957A (en) * 1973-04-02 1984-10-30 Eli Lilly And Company Use of vindesine in treating acute lymphatic leukemia and _other susceptible neoplasms
US4117113A (en) * 1974-06-25 1978-09-26 National Research Development Corporation Immunological preparations
US4235871A (en) * 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4331654A (en) * 1980-06-13 1982-05-25 Eli Lilly And Company Magnetically-localizable, biodegradable lipid microspheres
US4362664A (en) * 1980-12-29 1982-12-07 Eli Lilly And Company Vinblastine oxazolidinedione disulfides and related compounds
GB2103485B (en) * 1981-08-10 1986-04-03 Wellcone Foundation Limited Th Liposomes containing antimonyanti-leishmanaisis drugs
US4565696A (en) * 1983-08-03 1986-01-21 The Regents Of The University Of California Production of immunogens by antigen conjugation to liposomes
JPS60100516A (ja) * 1983-11-04 1985-06-04 Takeda Chem Ind Ltd 徐放型マイクロカプセルの製造法
US4663167A (en) * 1984-04-16 1987-05-05 The Board Of Regents Of The University Of Texas System Composition and method for treatment of disseminated fungal infections in mammals
CA1270198A (en) * 1984-08-08 1990-06-12 Marcel B. Bally Encapsulation of antineoplastic agents in liposomes
US4771782A (en) * 1986-11-14 1988-09-20 Millar Instruments, Inc. Method and assembly for introducing multiple catheters into a biological vessel

Also Published As

Publication number Publication date
CA1339077C (en) 1997-07-29
AU625308B2 (en) 1992-07-09
EP0416014B1 (en) 1994-03-23
EP0416014A4 (en) 1991-08-14
EP0416014A1 (en) 1991-03-13
AU3742489A (en) 1989-12-12
IE891661L (en) 1989-11-23
DK279890D0 (da) 1990-11-23
US4952408A (en) 1990-08-28
DE68914154T2 (de) 1994-10-20
DE68914154D1 (de) 1994-04-28
JPH03504381A (ja) 1991-09-26
WO1989011292A1 (en) 1989-11-30
IE64513B1 (en) 1995-08-09
DK175869B1 (da) 2005-04-25

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