DK2750709T3 - TREATMENT OF KAKEKSI - Google Patents
TREATMENT OF KAKEKSI Download PDFInfo
- Publication number
- DK2750709T3 DK2750709T3 DK12834301.9T DK12834301T DK2750709T3 DK 2750709 T3 DK2750709 T3 DK 2750709T3 DK 12834301 T DK12834301 T DK 12834301T DK 2750709 T3 DK2750709 T3 DK 2750709T3
- Authority
- DK
- Denmark
- Prior art keywords
- pharmaceutical composition
- subject
- use according
- cachexia
- patients
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- C07K16/245—IL-1
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/06—Anabolic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161538309P | 2011-09-23 | 2011-09-23 | |
| PCT/US2012/056492 WO2013043973A2 (en) | 2011-09-23 | 2012-09-21 | Cachexia treatment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2750709T3 true DK2750709T3 (en) | 2018-12-03 |
Family
ID=47911521
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK12834301.9T DK2750709T3 (en) | 2011-09-23 | 2012-09-21 | TREATMENT OF KAKEKSI |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US9809649B2 (OSRAM) |
| EP (1) | EP2750709B1 (OSRAM) |
| JP (1) | JP6204915B2 (OSRAM) |
| KR (1) | KR102039198B1 (OSRAM) |
| CN (2) | CN108404127B (OSRAM) |
| AU (1) | AU2012312225B2 (OSRAM) |
| CA (1) | CA2849710C (OSRAM) |
| DK (1) | DK2750709T3 (OSRAM) |
| ES (1) | ES2695102T3 (OSRAM) |
| IL (1) | IL231622B (OSRAM) |
| MX (1) | MX356808B (OSRAM) |
| PH (1) | PH12014500645A1 (OSRAM) |
| PT (1) | PT2750709T (OSRAM) |
| RU (1) | RU2622021C2 (OSRAM) |
| WO (1) | WO2013043973A2 (OSRAM) |
| ZA (1) | ZA201402057B (OSRAM) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011159976A2 (en) | 2010-06-18 | 2011-12-22 | Xbiotech, Inc. | Arthritis treatment |
| CN103153340A (zh) | 2010-08-23 | 2013-06-12 | 埃克斯生物科技公司 | 对肿瘤疾病的治疗 |
| US9724409B2 (en) | 2011-04-01 | 2017-08-08 | Xbiotech, Inc. | Treatment of inflammatory skin disease |
| ES2695102T3 (es) | 2011-09-23 | 2019-01-02 | Xbiotech Inc | Tratamiento para la caquexia |
| US9545441B2 (en) | 2012-09-18 | 2017-01-17 | Xbiotech, Inc. | Treatment of diabetes |
| US10485502B2 (en) * | 2016-12-20 | 2019-11-26 | General Electric Company | System and method for assessing muscle function of a patient |
| EP4467565A3 (en) | 2016-12-21 | 2025-03-12 | Amgen Inc. | Anti-tnf alpha antibody formulations |
| CN110382001A (zh) | 2017-02-16 | 2019-10-25 | 埃克斯生物科技公司 | 化脓性汗腺炎的治疗 |
| US10975146B2 (en) | 2018-06-29 | 2021-04-13 | Cedars-Sinai Medical Center | Interleukin-1 inhibition for combination treatment of pancreatic cancer |
Family Cites Families (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH652145A5 (de) | 1982-01-22 | 1985-10-31 | Sandoz Ag | Verfahren zur in vitro-herstellung von hybridomen welche humane monoklonale antikoerper erzeugen. |
| US5672347A (en) | 1984-07-05 | 1997-09-30 | Genentech, Inc. | Tumor necrosis factor antagonists and their use |
| US5168062A (en) | 1985-01-30 | 1992-12-01 | University Of Iowa Research Foundation | Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence |
| US4965198A (en) | 1985-12-24 | 1990-10-23 | Konica Corporation | Monoclonal antibody and method of manufacturing hybridoma producing the same |
| DE3631229A1 (de) | 1986-09-13 | 1988-03-24 | Basf Ag | Monoklonale antikoerper gegen humanen tumornekrosefaktor (tnf) und deren verwendung |
| DK590387A (da) | 1986-11-13 | 1988-05-14 | Otsuka Pharma Co Ltd | Antistoffer mod interleukin-1 |
| US5034316A (en) | 1987-03-30 | 1991-07-23 | The Regents Of The University Of California | In vitro human monoclonal IgG rheumatoid factor autoantibody |
| FR2640146B1 (fr) | 1988-12-08 | 1993-12-24 | Commissariat A Energie Atomique | Anticorps monoclonaux anti-interleukines 1(alpha) et 1(beta), leur procede de production et applications desdits anticorps a la detection des interleukines 1(alpha) et 1(beta) et en therapeutique |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| JPH04504253A (ja) | 1989-03-27 | 1992-07-30 | セントカー・インコーポレーテツド | ＩｇＭ抗体の安定化のための配合物 |
| GB9122820D0 (en) | 1991-10-28 | 1991-12-11 | Wellcome Found | Stabilised antibodies |
| WO1994008624A2 (en) | 1992-10-14 | 1994-04-28 | Sterling Winthrop Inc. | Therapeutic and diagnostic imaging compositions and methods |
| ATE204299T1 (de) | 1993-03-05 | 2001-09-15 | Bayer Ag | Humane monoklonale anti-tnf alpha antikörper |
| EP0659766A1 (en) | 1993-11-23 | 1995-06-28 | Schering-Plough | Human monoclonal antibodies against human cytokines and methods of making and using such antibodies |
| US5959085A (en) | 1993-11-23 | 1999-09-28 | Schering Corporation | Human monoclonal antibodies against human cytokines and methods of making and using such antibodies |
| GB9509620D0 (en) | 1995-05-12 | 1995-07-05 | Nat Blood Authority | Transepithelial transport of molecular species |
| WO1997002479A2 (en) | 1995-06-30 | 1997-01-23 | Yale University | Human monoclonal anti-tumor antibodies |
| US6090382A (en) | 1996-02-09 | 2000-07-18 | Basf Aktiengesellschaft | Human antibodies that bind human TNFα |
| SE9802402D0 (sv) | 1998-07-03 | 1998-07-03 | Karolinska Innovations Ab | Method of diagnosing cardiovascular disease and early atherosclerosis |
| US20030040617A9 (en) | 1999-03-12 | 2003-02-27 | Rosen Craig A. | Nucleic acids, proteins and antibodies |
| US20030232054A1 (en) | 2000-01-25 | 2003-12-18 | Tang Y. Tom | Novel nucleic acids and polypeptides |
| US20020131954A1 (en) | 2000-05-02 | 2002-09-19 | Tobinick Edward L. | Interleukin antagonists for the treatment of neurological, retinal and muscular disorders |
| AU2007202323C1 (en) | 2000-06-29 | 2012-04-12 | Abbvie Inc. | Dual specificity antibodies and methods of making and using |
| US20040086507A1 (en) | 2000-10-19 | 2004-05-06 | Kenya Shitara | Antibody inhibiting vplf activity |
| US20030026806A1 (en) | 2000-10-27 | 2003-02-06 | Amgen Inc. | Antibodies and other selective IL-1 binding agents that allow binding to IL-1 receptor but not activation thereof |
| AU2002343609B2 (en) | 2001-11-16 | 2008-12-11 | Als Therapy Development Foundation, Inc. | Treatment of neurodegenerative disorders through the modulation of the polyamine pathway |
| NZ566539A (en) | 2002-09-06 | 2010-01-29 | Medarex Inc | Therapeutic human anti-IL-1R1 monoclonal antibody |
| JP4450644B2 (ja) | 2003-03-03 | 2010-04-14 | 日本化薬株式会社 | Ａｍｆ類を有効成分とする医薬製剤 |
| US20040224893A1 (en) | 2003-05-06 | 2004-11-11 | Li-Hsien Wang | Methods of using IL-1 antagonists to treat neointimal hyperplasia |
| HN2004000285A (es) | 2003-08-04 | 2006-04-27 | Pfizer Prod Inc | ANTICUERPOS DIRIGIDOS A c-MET |
| US7799327B2 (en) | 2003-12-24 | 2010-09-21 | Henry John Smith | Autoantibodies utilized as carrier agents for pharmaceutical compounds used in cancer treatment |
| US7105183B2 (en) | 2004-02-03 | 2006-09-12 | The Regents Of The University Of California | Chlorite in the treatment of neurodegenerative disease |
| US8957056B2 (en) | 2004-05-25 | 2015-02-17 | Sloan-Kettering Instiute For Cancer Research | Migrastatin analogs in the treatment of cancer |
| US20050276807A1 (en) | 2004-06-15 | 2005-12-15 | Advanced Biotherapy, Inc. | Treatment of acne |
| WO2006036936A2 (en) | 2004-09-27 | 2006-04-06 | Bridge Pharma, Inc. | The s-isomer of 2-{2-[n-(2-indanyl)-n-phenylamino]ethyl}piperidine and other dermal anesthetic agents |
| AU2005314392B2 (en) | 2004-12-09 | 2011-04-14 | Centocor, Inc. | Anti-integrin immunoconjugates, methods and uses |
| DE602006014691D1 (de) | 2005-08-02 | 2010-07-15 | Xbiotech Inc | DIAGNOSE, BEHANDLUNG UND PRÄVENTION VON GEFÄSSERKRANKUNGEN MITTELS IL-1alpha-AUTOANTIKÖRPERN |
| US20090215992A1 (en) | 2005-08-19 | 2009-08-27 | Chengbin Wu | Dual variable domain immunoglobulin and uses thereof |
| US7612181B2 (en) | 2005-08-19 | 2009-11-03 | Abbott Laboratories | Dual variable domain immunoglobulin and uses thereof |
| EP1931383A1 (en) | 2005-09-28 | 2008-06-18 | Cytos Biotechnology AG | Interleukin-1 conjugates and uses thereof |
| EP2021026A1 (en) | 2006-04-14 | 2009-02-11 | Novartis AG | Use of il-i antibodies for treating ophthalmic disorders |
| ES2384278T3 (es) | 2006-05-15 | 2012-07-03 | Xbiotech, Inc | IL-1-alfa para su uso en un procedimiento de tratamiento de placas ateroscleróticas |
| US20110008282A1 (en) | 2006-05-15 | 2011-01-13 | Xbiotech, Inc. | IL-1alpha immunization induces autoantibodies protective against atherosclerosis |
| DK2109623T3 (da) | 2006-05-22 | 2012-01-30 | Xbiotech Inc | Cancerbehandling med anti-IL-1-antistoffer |
| HRP20140172T1 (hr) | 2006-05-30 | 2014-03-28 | Genentech, Inc. | Protutijela i imunokonjugati kao i njihove uporabe |
| EP2114443A4 (en) | 2006-12-29 | 2011-08-10 | Abbott Lab | IL-1A / IL-1B ANTIBODY WITH DOUBLE SPECIFICITY |
| CN102056485A (zh) | 2008-04-15 | 2011-05-11 | 萨可德公司 | 用于局部治疗免疫相关疾病的局部lfa-1拮抗剂 |
| US8034337B2 (en) | 2008-05-30 | 2011-10-11 | Xbiotech, Inc. | Interleukin-1α antibodies |
| AU2009291536B2 (en) | 2008-09-12 | 2012-08-16 | Xbiotech Inc. | Targeting pathogenic monocytes |
| SG172855A1 (en) * | 2009-01-29 | 2011-08-29 | Abbott Lab | Il-1 binding proteins |
| AR078650A1 (es) | 2009-10-15 | 2011-11-23 | Abbott Lab | Anticuerpo de union a il-1 beta |
| WO2011159976A2 (en) | 2010-06-18 | 2011-12-22 | Xbiotech, Inc. | Arthritis treatment |
| CN103153340A (zh) | 2010-08-23 | 2013-06-12 | 埃克斯生物科技公司 | 对肿瘤疾病的治疗 |
| US9724409B2 (en) | 2011-04-01 | 2017-08-08 | Xbiotech, Inc. | Treatment of inflammatory skin disease |
| DK2694107T3 (en) | 2011-04-01 | 2018-12-10 | Xbiotech Inc | TREATMENT OF DERMATOLOGICAL DISORDERS |
| ES2695102T3 (es) | 2011-09-23 | 2019-01-02 | Xbiotech Inc | Tratamiento para la caquexia |
| US20130195877A1 (en) | 2012-01-31 | 2013-08-01 | Xbiotech, Inc. | Treatment of cachexia by targeting interleukin-1 beta |
| US9545441B2 (en) | 2012-09-18 | 2017-01-17 | Xbiotech, Inc. | Treatment of diabetes |
| AU2013327501B2 (en) | 2012-10-04 | 2018-08-09 | Xbiotech Inc. | Treating vascular disease and complications thereof |
| KR20150064091A (ko) | 2012-10-04 | 2015-06-10 | 엑스바이오테크, 인크. | 정신의학적 병태의 치료법 |
-
2012
- 2012-09-21 ES ES12834301T patent/ES2695102T3/es active Active
- 2012-09-21 MX MX2014003402A patent/MX356808B/es active IP Right Grant
- 2012-09-21 RU RU2014111662A patent/RU2622021C2/ru active
- 2012-09-21 AU AU2012312225A patent/AU2012312225B2/en active Active
- 2012-09-21 CN CN201810252345.4A patent/CN108404127B/zh active Active
- 2012-09-21 CA CA2849710A patent/CA2849710C/en active Active
- 2012-09-21 WO PCT/US2012/056492 patent/WO2013043973A2/en not_active Ceased
- 2012-09-21 PT PT12834301T patent/PT2750709T/pt unknown
- 2012-09-21 US US13/624,004 patent/US9809649B2/en active Active
- 2012-09-21 KR KR1020147010546A patent/KR102039198B1/ko active Active
- 2012-09-21 DK DK12834301.9T patent/DK2750709T3/en active
- 2012-09-21 CN CN201280054593.9A patent/CN103906536A/zh active Pending
- 2012-09-21 PH PH1/2014/500645A patent/PH12014500645A1/en unknown
- 2012-09-21 EP EP12834301.9A patent/EP2750709B1/en active Active
- 2012-09-21 JP JP2014531996A patent/JP6204915B2/ja active Active
-
2014
- 2014-03-20 IL IL231622A patent/IL231622B/en active IP Right Grant
- 2014-03-20 ZA ZA2014/02057A patent/ZA201402057B/en unknown
-
2017
- 2017-10-11 US US15/730,218 patent/US10202449B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| MX2014003402A (es) | 2015-03-05 |
| PT2750709T (pt) | 2018-11-22 |
| CN108404127A (zh) | 2018-08-17 |
| WO2013043973A2 (en) | 2013-03-28 |
| AU2012312225A1 (en) | 2014-04-10 |
| RU2014111662A (ru) | 2015-10-27 |
| KR102039198B1 (ko) | 2019-10-31 |
| JP2014526559A (ja) | 2014-10-06 |
| US20180037647A1 (en) | 2018-02-08 |
| PH12014500645A1 (en) | 2014-05-05 |
| AU2012312225B2 (en) | 2017-10-05 |
| ES2695102T3 (es) | 2019-01-02 |
| EP2750709A4 (en) | 2015-06-10 |
| US9809649B2 (en) | 2017-11-07 |
| IL231622A0 (en) | 2014-05-28 |
| HK1199616A1 (en) | 2015-07-10 |
| ZA201402057B (en) | 2016-08-31 |
| CA2849710C (en) | 2020-04-28 |
| US10202449B2 (en) | 2019-02-12 |
| EP2750709B1 (en) | 2018-08-15 |
| MX356808B (es) | 2018-06-14 |
| IL231622B (en) | 2018-10-31 |
| KR20140078690A (ko) | 2014-06-25 |
| CN108404127B (zh) | 2025-12-12 |
| US20130078258A1 (en) | 2013-03-28 |
| EP2750709A2 (en) | 2014-07-09 |
| CN103906536A (zh) | 2014-07-02 |
| JP6204915B2 (ja) | 2017-09-27 |
| RU2622021C2 (ru) | 2017-06-08 |
| CA2849710A1 (en) | 2013-03-28 |
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