DK274882A - Fremgangsmaade til fremstilling af 4alfa,5alfa-epoxy-3,20-dioxopregnen-2alfa,16alfa-dicarbonitril og mellemprodukt herved - Google Patents

Fremgangsmaade til fremstilling af 4alfa,5alfa-epoxy-3,20-dioxopregnen-2alfa,16alfa-dicarbonitril og mellemprodukt herved Download PDF

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Publication number
DK274882A
DK274882A DK274882A DK274882A DK274882A DK 274882 A DK274882 A DK 274882A DK 274882 A DK274882 A DK 274882A DK 274882 A DK274882 A DK 274882A DK 274882 A DK274882 A DK 274882A
Authority
DK
Denmark
Prior art keywords
dioxopregnen
4alfa
16alfa
2alfa
dicarbonitril
Prior art date
Application number
DK274882A
Other languages
Danish (da)
English (en)
Inventor
R G Christiansen
M R Bell
H P Schane
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of DK274882A publication Critical patent/DK274882A/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036Nitrogen-containing hetero ring
    • C07J71/0057Nitrogen and oxygen
    • C07J71/0063Nitrogen and oxygen at position 2(3)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/001Oxiranes

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK274882A 1981-06-19 1982-06-18 Fremgangsmaade til fremstilling af 4alfa,5alfa-epoxy-3,20-dioxopregnen-2alfa,16alfa-dicarbonitril og mellemprodukt herved DK274882A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/275,294 US4331663A (en) 1981-06-19 1981-06-19 4α,5α-Epoxy-3,20-dioxopregnane-2α,16α-dicarbonitrile and intermediates and process for preparation, method of use and compositions thereof

Publications (1)

Publication Number Publication Date
DK274882A true DK274882A (da) 1982-12-20

Family

ID=23051676

Family Applications (1)

Application Number Title Priority Date Filing Date
DK274882A DK274882A (da) 1981-06-19 1982-06-18 Fremgangsmaade til fremstilling af 4alfa,5alfa-epoxy-3,20-dioxopregnen-2alfa,16alfa-dicarbonitril og mellemprodukt herved

Country Status (8)

Country Link
US (1) US4331663A (de)
EP (1) EP0072894A1 (de)
JP (1) JPS581000A (de)
KR (1) KR840000582A (de)
AU (1) AU8427982A (de)
DK (1) DK274882A (de)
GR (1) GR75942B (de)
NZ (1) NZ200779A (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59221293A (ja) * 1983-05-26 1984-12-12 株式会社東京タツノ 給油装置
US4755595A (en) * 1985-11-01 1988-07-05 Sterling Drug Inc. Enhanced production of 4,5-unsaturated steroids utilizing methanol solvation
JP3226807B2 (ja) 1996-11-20 2001-11-05 静岡日本電気株式会社 無線呼出システム用の自動周波数補正装置および自動周波数補正方法
GB2375958B (en) * 2001-04-09 2005-03-02 George Margetts The use of steroids to lower the levels of cortisol
GB2400554B (en) * 2003-04-16 2007-04-18 George Margetts Treatment of angiotensin II-induced cardiovascular disease

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2817671A (en) * 1956-03-20 1957-12-24 Searle & Co 16-cyano and 16-cyanoalkyl 3, 20-dioxy-genated pregnenes
US3135743A (en) * 1960-06-29 1964-06-02 Sterling Drug Inc Steroido[2. 3-d]isoxazoles and preparation thereof
US3296255A (en) * 1963-11-29 1967-01-03 Sterling Drug Inc 2-cyano steroids
GB1123770A (en) * 1966-11-15 1968-08-14 Sterling Drug Inc 2-cyano-3-oxo-steroids
DE2336438C2 (de) * 1973-07-14 1983-07-07 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von 17 β- Oxalylsteroiden

Also Published As

Publication number Publication date
US4331663A (en) 1982-05-25
KR840000582A (ko) 1984-02-25
EP0072894A1 (de) 1983-03-02
AU8427982A (en) 1982-12-23
NZ200779A (en) 1985-04-30
GR75942B (de) 1984-08-02
JPS581000A (ja) 1983-01-06

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment