DK272182A - Fremgangsmaade til fremstilling af oralt effektive aporphin-forbindelser eller dopamin-agonist-forbindelser med ikke aporphinstruktur eller farmaceutisk acceptable syreadditionssalte deraf - Google Patents
Fremgangsmaade til fremstilling af oralt effektive aporphin-forbindelser eller dopamin-agonist-forbindelser med ikke aporphinstruktur eller farmaceutisk acceptable syreadditionssalte deraf Download PDFInfo
- Publication number
- DK272182A DK272182A DK272182A DK272182A DK272182A DK 272182 A DK272182 A DK 272182A DK 272182 A DK272182 A DK 272182A DK 272182 A DK272182 A DK 272182A DK 272182 A DK272182 A DK 272182A
- Authority
- DK
- Denmark
- Prior art keywords
- aporphin
- compounds
- procedure
- preparation
- acid addition
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 2
- MAWRLMCDVKBYJB-UHFFFAOYSA-N (+-)-normecambroline Natural products C12=C3C4=CC(O)=CC=C4CC2NCCC1=CC1=C3OCO1 MAWRLMCDVKBYJB-UHFFFAOYSA-N 0.000 title 1
- ZTXGGRMVULLHNF-UHFFFAOYSA-N Dehydroneolitsine Natural products CN1CCc2cc3OCOc3c4c5cc6OCOc6cc5cc1c24 ZTXGGRMVULLHNF-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- 239000003136 dopamine receptor stimulating agent Chemical class 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/06—Peri-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/18—Ring systems of four or more rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27477281A | 1981-06-18 | 1981-06-18 | |
| US34684182A | 1982-02-08 | 1982-02-08 | |
| US35891782A | 1982-03-17 | 1982-03-17 | |
| US35891882A | 1982-03-17 | 1982-03-17 | |
| US06/379,557 US4543256A (en) | 1982-03-17 | 1982-05-18 | (-)-10,1L Methylenedioxy-N-N-propylnoraporphine and methods employing it for inhibiting the effects of epileptic seizures and for prevention and treatment of duodenal ulcers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK272182A true DK272182A (da) | 1982-12-19 |
Family
ID=27540584
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK272182A DK272182A (da) | 1981-06-18 | 1982-06-17 | Fremgangsmaade til fremstilling af oralt effektive aporphin-forbindelser eller dopamin-agonist-forbindelser med ikke aporphinstruktur eller farmaceutisk acceptable syreadditionssalte deraf |
Country Status (8)
| Country | Link |
|---|---|
| CA (1) | CA1270253A (it) |
| DE (1) | DE3222840A1 (it) |
| DK (1) | DK272182A (it) |
| FR (1) | FR2508043B1 (it) |
| GB (1) | GB2105323B (it) |
| IE (1) | IE53161B1 (it) |
| IT (1) | IT1191200B (it) |
| NL (1) | NL8202467A (it) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1990012574A1 (en) * | 1989-04-25 | 1990-11-01 | Northeastern University | Dopamine agonist compounds |
| AU4536599A (en) * | 1999-06-21 | 2001-01-09 | Geochemistry Research Limited | Metal-rich silica products from geothermal and synthetic aqueous systems nen wie |
| JP5734957B2 (ja) | 2009-04-21 | 2015-06-17 | パーデュー・リサーチ・ファウンデーションＰｕｒｄｕｅ Ｒｅｓｅａｒｃｈ Ｆｏｕｎｄａｔｉｏｎ | ドーパミンレセプターのオクタヒドロベンゾイソキノリンモジュレーター及びその使用 |
| WO2020070099A1 (en) | 2018-10-02 | 2020-04-09 | H. Lundbeck A/S | Administration of catecholamine prodrugs in combination with a 5-ht2b antagonist |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3717643A (en) * | 1967-05-04 | 1973-02-20 | Sterling Drug Inc | N-substituted-norapomorphines |
| US3810987A (en) * | 1972-06-12 | 1974-05-14 | Merck & Co Inc | Blood pressure lowering method using an aporphine |
-
1982
- 1982-06-17 IT IT67776/82A patent/IT1191200B/it active
- 1982-06-17 DK DK272182A patent/DK272182A/da not_active Application Discontinuation
- 1982-06-17 IE IE1441/82A patent/IE53161B1/en unknown
- 1982-06-17 CA CA000405440A patent/CA1270253A/en not_active Expired
- 1982-06-17 NL NL8202467A patent/NL8202467A/nl not_active Application Discontinuation
- 1982-06-18 FR FR8210734A patent/FR2508043B1/fr not_active Expired
- 1982-06-18 GB GB08217644A patent/GB2105323B/en not_active Expired
- 1982-06-18 DE DE19823222840 patent/DE3222840A1/de not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| GB2105323A (en) | 1983-03-23 |
| GB2105323B (en) | 1985-12-11 |
| IE53161B1 (en) | 1988-08-03 |
| DE3222840A1 (de) | 1983-05-05 |
| IT8267776A0 (it) | 1982-06-17 |
| FR2508043A1 (fr) | 1982-12-24 |
| FR2508043B1 (fr) | 1987-04-30 |
| IE821441L (en) | 1982-12-18 |
| NL8202467A (nl) | 1983-01-17 |
| CA1270253A (en) | 1990-06-12 |
| IT1191200B (it) | 1988-02-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |