DK2699247T3 - PROCEDURE FOR COMBINED CONDITIONING AND CHEMOS SELECTION IN A SIMPLE CYCLE - Google Patents
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Developmental Biology & Embryology (AREA)
- Chemical & Material Sciences (AREA)
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- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
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- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
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- Zoology (AREA)
- Virology (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Transplantation (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161477440P | 2011-04-20 | 2011-04-20 | |
| PCT/US2012/034586 WO2012145723A1 (en) | 2011-04-20 | 2012-04-20 | Method for combined conditioning and chemoselection in a single cycle |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2699247T3 true DK2699247T3 (en) | 2018-06-14 |
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| Application Number | Title | Priority Date | Filing Date |
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| DK12774246.8T DK2699247T3 (en) | 2011-04-20 | 2012-04-20 | PROCEDURE FOR COMBINED CONDITIONING AND CHEMOS SELECTION IN A SIMPLE CYCLE |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9439928B2 (enExample) |
| EP (3) | EP2699247B1 (enExample) |
| JP (4) | JP5997257B2 (enExample) |
| AU (3) | AU2012245269B2 (enExample) |
| CA (1) | CA2861440C (enExample) |
| DK (1) | DK2699247T3 (enExample) |
| ES (1) | ES2672693T3 (enExample) |
| PL (1) | PL2699247T3 (enExample) |
| RU (2) | RU2611396C2 (enExample) |
| TR (1) | TR201808037T4 (enExample) |
| WO (1) | WO2012145723A1 (enExample) |
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| RU2611396C2 (ru) * | 2011-04-20 | 2017-02-21 | Де Реджентс Оф Де Юниверсити Оф Калифорния | Способ совместного кондиционирования и хемоселекции за один цикл |
| US9682106B2 (en) * | 2011-04-20 | 2017-06-20 | The Regents Of The University Of California | Method for combined conditioning and chemoselection in a single cycle |
| US20170209447A1 (en) * | 2014-08-07 | 2017-07-27 | Nitor Therapeutics | Use of PNP Inhibitor to Treat Relapse of Malignancy after Hematopoietic Stem Cell Transplant |
| US20180140606A1 (en) * | 2016-11-18 | 2018-05-24 | Calimmune, Inc. | In Vivo Chemoselection with Low Dose Thioguanine |
| JP6783674B2 (ja) | 2017-01-20 | 2020-11-11 | 株式会社日立ハイテク | 自動分析装置、自動分析装置における廃液方法、及び、三方電磁弁 |
| CA3070242A1 (en) * | 2017-07-18 | 2019-01-24 | Calimmune, Inc. | Compositions and methods for treating beta-hemoglobinopathies |
| EP3654994B1 (en) * | 2017-07-18 | 2022-12-28 | CSL Behring Gene Therapy, Inc. | A modulatable switch for selection of donor modified cells |
| WO2019074980A1 (en) * | 2017-10-09 | 2019-04-18 | Stowers Institute For Medical Research | METHODS AND COMPOSITIONS FOR EXPANSION OF CELL POPULATION |
| EP3897831A1 (en) * | 2018-12-23 | 2021-10-27 | CSL Behring LLC | Donor t-cells with kill switch |
| CN113518825A (zh) * | 2018-12-23 | 2021-10-19 | 美国杰特贝林生物制品有限公司 | Wiskott-aldrich综合征的造血干细胞基因疗法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5965126A (en) | 1996-03-25 | 1999-10-12 | The Penn State Research Foundation | use of mutant alkyltransferases for gene therapy to protect from toxicity of therapeutic alkylating agents |
| WO1997043900A1 (en) * | 1996-05-24 | 1997-11-27 | The President And Fellows Of Harvard College | In vivo selection |
| AU7605796A (en) | 1996-11-04 | 1998-05-29 | Saint Jude Children's Research Hospital | (in vivo) selection of primitive hematopoietic cells |
| DE69841058D1 (de) * | 1997-11-14 | 2009-09-24 | Gen Hospital Corp | Behandlung von hämatologischen störungen |
| GB9904281D0 (en) * | 1999-02-24 | 1999-04-21 | Reneuron Ltd | Transplantation |
| US7094885B2 (en) * | 1999-07-11 | 2006-08-22 | Neorx Corporation | Skeletal-targeted radiation to treat bone-associated pathologies |
| US20030032003A1 (en) * | 2000-02-02 | 2003-02-13 | Schiestl Robert H. | In vivo selection |
| WO2002040049A2 (en) * | 2000-11-14 | 2002-05-23 | The General Hospital Corporation | Blockade of t cell migration into epithelial gvhd target tissues |
| US7037900B2 (en) * | 2001-10-12 | 2006-05-02 | Supergen, Inc. | Composition and method for treating graft-versus-host disease |
| RU2611396C2 (ru) * | 2011-04-20 | 2017-02-21 | Де Реджентс Оф Де Юниверсити Оф Калифорния | Способ совместного кондиционирования и хемоселекции за один цикл |
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2012
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- 2012-04-20 AU AU2012245269A patent/AU2012245269B2/en not_active Ceased
- 2012-04-20 WO PCT/US2012/034586 patent/WO2012145723A1/en not_active Ceased
- 2012-04-20 ES ES12774246.8T patent/ES2672693T3/es active Active
- 2012-04-20 CA CA2861440A patent/CA2861440C/en active Active
- 2012-04-20 RU RU2017104621A patent/RU2728867C2/ru active
- 2012-04-20 EP EP12774246.8A patent/EP2699247B1/en active Active
- 2012-04-20 JP JP2014506605A patent/JP5997257B2/ja not_active Expired - Fee Related
- 2012-04-20 EP EP18159906.9A patent/EP3384912B1/en not_active Not-in-force
- 2012-04-20 EP EP20190457.0A patent/EP3799876A1/en not_active Withdrawn
- 2012-04-20 PL PL12774246T patent/PL2699247T3/pl unknown
- 2012-04-20 TR TR2018/08037T patent/TR201808037T4/tr unknown
- 2012-04-20 US US14/112,878 patent/US9439928B2/en not_active Expired - Fee Related
- 2012-04-20 DK DK12774246.8T patent/DK2699247T3/en active
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2016
- 2016-08-25 JP JP2016164295A patent/JP6266716B2/ja not_active Expired - Fee Related
- 2016-11-17 AU AU2016259368A patent/AU2016259368B2/en not_active Ceased
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2017
- 2017-12-20 JP JP2017243476A patent/JP6560332B2/ja not_active Expired - Fee Related
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2018
- 2018-02-09 AU AU2018200967A patent/AU2018200967B2/en not_active Ceased
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2019
- 2019-07-18 JP JP2019132856A patent/JP6799117B2/ja not_active Expired - Fee Related
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