DK2691398T3 - Fremgangsmåder til syntetisering af metalmesoporfyriner - Google Patents

Fremgangsmåder til syntetisering af metalmesoporfyriner Download PDF

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Publication number
DK2691398T3
DK2691398T3 DK12765367.3T DK12765367T DK2691398T3 DK 2691398 T3 DK2691398 T3 DK 2691398T3 DK 12765367 T DK12765367 T DK 12765367T DK 2691398 T3 DK2691398 T3 DK 2691398T3
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DK
Denmark
Prior art keywords
tin
mesoporphyrin
reaction
hours
product
Prior art date
Application number
DK12765367.3T
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English (en)
Inventor
Christopher P Boucher
David Roe
Original Assignee
Infacare Pharmaceutical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Infacare Pharmaceutical Corp filed Critical Infacare Pharmaceutical Corp
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Publication of DK2691398T3 publication Critical patent/DK2691398T3/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/22—Tin compounds
    • C07F7/2284—Compounds with one or more Sn-N linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Claims (4)

1. Fremgangsmåde til syntetisering af en tinmesoporfyrinforbindelse, omfattende transmetallering af hemin og hydrogenering af tinprotoporfyrin IX.
2. Fremgangsmåde til syntetisering af en tinmesoporfyrinforbindelse, omfattende dannelse af en protoporfyrinmethylester og indføring af tin i protoporfy-rinmethylesteren og hydrogenering af tinprotoporfyrinmethylesteren.
3. Fremgangsmåde ifølge krav 1 eller 2, hvor tin vælges blandt tinoxid, tinchlorid, tinsulfat, tinbromid, tinoxalat, tinpyrophosphathydrat, tin-2-ethylhexanoat, tinmethansulfonsyre og tintrifluormethansulfonat.
4. Fremgangsmåde ifølge et af kravene 1 eller 2, hvor tinmesoporfyrinforbindelsen er stannsoporfin.
DK12765367.3T 2011-03-30 2012-03-30 Fremgangsmåder til syntetisering af metalmesoporfyriner DK2691398T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201161469792P 2011-03-30 2011-03-30
US201161469791P 2011-03-30 2011-03-30
US201161532301P 2011-09-08 2011-09-08
PCT/US2012/031557 WO2012135686A1 (en) 2011-03-30 2012-03-30 Methods for synthesizing metal mesoporphyrins

Publications (1)

Publication Number Publication Date
DK2691398T3 true DK2691398T3 (da) 2017-01-16

Family

ID=46928082

Family Applications (1)

Application Number Title Priority Date Filing Date
DK12765367.3T DK2691398T3 (da) 2011-03-30 2012-03-30 Fremgangsmåder til syntetisering af metalmesoporfyriner

Country Status (8)

Country Link
US (5) US8735574B2 (da)
EP (1) EP2691398B1 (da)
DK (1) DK2691398T3 (da)
ES (1) ES2609110T3 (da)
HU (1) HUE032290T2 (da)
PL (1) PL2691398T3 (da)
PT (1) PT2691398T (da)
WO (1) WO2012135686A1 (da)

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Also Published As

Publication number Publication date
WO2012135686A1 (en) 2012-10-04
HUE032290T2 (en) 2017-09-28
EP2691398A1 (en) 2014-02-05
ES2609110T3 (es) 2017-04-18
US9688705B2 (en) 2017-06-27
PL2691398T3 (pl) 2017-07-31
PT2691398T (pt) 2017-01-02
US20160024124A1 (en) 2016-01-28
US20190002481A1 (en) 2019-01-03
US9181285B2 (en) 2015-11-10
US20120253033A1 (en) 2012-10-04
US10533024B2 (en) 2020-01-14
US8735574B2 (en) 2014-05-27
EP2691398B1 (en) 2016-09-28
US20140228560A1 (en) 2014-08-14
US20170260217A1 (en) 2017-09-14
EP2691398A4 (en) 2014-10-08

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