DK2641970T3 - Modulation of gene expression by oligomers targeted to chromosomal DNA - Google Patents
Modulation of gene expression by oligomers targeted to chromosomal DNA Download PDFInfo
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- DK2641970T3 DK2641970T3 DK13162209.4T DK13162209T DK2641970T3 DK 2641970 T3 DK2641970 T3 DK 2641970T3 DK 13162209 T DK13162209 T DK 13162209T DK 2641970 T3 DK2641970 T3 DK 2641970T3
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- oligomer
- stranded rna
- isolated
- gene
- promoter
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| EP06849880.7A EP1957648B1 (en) | 2005-11-17 | 2006-11-13 | Modulation of gene expression by oligomers targeted to chromosomal dna |
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| DK2641970T3 true DK2641970T3 (en) | 2015-02-02 |
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| CA (1) | CA2629664A1 (https=) |
| DK (1) | DK2641970T3 (https=) |
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| US7480382B2 (en) * | 2003-09-30 | 2009-01-20 | Microsoft Corporation | Image file container |
| US8999943B2 (en) * | 2005-03-14 | 2015-04-07 | Board Of Regents, The University Of Texas System | Antigene oligomers inhibit transcription |
| CA2604532C (en) | 2005-04-15 | 2017-03-07 | The Regents Of The University Of California | Small activating rna molecules and methods of use |
| JP5066095B2 (ja) | 2005-11-17 | 2012-11-07 | ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム | 染色体ｄｎａに標的化されるオリゴマーによる遺伝子発現の調節 |
| US8288354B2 (en) | 2005-12-28 | 2012-10-16 | The Scripps Research Institute | Natural antisense and non-coding RNA transcripts as drug targets |
| EP3342415B1 (en) | 2006-08-08 | 2022-01-26 | Rheinische Friedrich-Wilhelms-Universität Bonn | Structure and use of 5' phosphate oligonucleotides |
| EP2205746A4 (en) * | 2007-10-04 | 2010-12-22 | Univ Texas | MODULATION OF GENE EXPRESSION WITH AGRNA AND GAPS WITH ANTISENSE TRANSCRIPTS AS A TARGET |
| WO2009099942A2 (en) * | 2008-01-31 | 2009-08-13 | Alnylam Pharmaceuticals, Inc. | Chemically modified oligonucleotides and uses thereof |
| EP2297323A1 (en) | 2008-05-21 | 2011-03-23 | Hartmann, Gunther | 5' triphosphate oligonucleotide with blunt end and uses thereof |
| CA2726052A1 (en) | 2008-06-04 | 2009-12-10 | The Board Of Regents Of The University Of Texas System | Modulation of gene expression through endogenous small rna targeting of gene promoters |
| WO2010014592A1 (en) * | 2008-07-29 | 2010-02-04 | The Board Of Regents Of The University Of Texas Sytem | Selective inhibition of polyglutamine protein expression |
| WO2010040112A2 (en) * | 2008-10-03 | 2010-04-08 | Curna, Inc. | Treatment of apolipoprotein-a1 related diseases by inhibition of natural antisense transcript to apolipoprotein-a1 |
| ES2600781T3 (es) | 2008-12-04 | 2017-02-10 | Curna, Inc. | Tratamiento para enfermedades relacionadas con el factor de crecimiento del endotelio vascular (vegf) mediante la inhibición de transcritos antisentido naturales de vegf |
| RU2620970C2 (ru) | 2008-12-04 | 2017-05-30 | КьюРНА,Инк., | Лечение связанных с эритропоэтином (еро) заболеваний путем ингибирования природного антисмыслового транскрипта к еро |
| CN102361985B (zh) | 2008-12-04 | 2017-06-20 | 库尔纳公司 | 通过抑制肿瘤抑制基因的天然反义转录物治疗肿瘤抑制基因相关性疾病 |
| WO2010093904A2 (en) | 2009-02-12 | 2010-08-19 | Curna, Inc. | Treatment of brain derived neurotrophic factor (bdnf) related diseases by inhibition of natural antisense transcript to bdnf |
| EP2408919B1 (en) | 2009-03-16 | 2017-10-18 | CuRNA, Inc. | Treatment of nuclear factor (erythroid-derived 2)-like 2 (nrf2) related diseases by inhibition of natural antisense transcript to nrf2 |
| CA2755404C (en) | 2009-03-17 | 2020-03-24 | Curna, Inc. | Treatment of delta-like 1 homolog (dlk1) related diseases by inhibition of natural antisense transcript to dlk1 |
| DE112010001703T5 (de) | 2009-04-21 | 2012-09-20 | Basf Plant Science Company Gmbh | RNA-vermittelte Induktion von Genexpression in Pflanzen |
| CN102803494A (zh) | 2009-04-21 | 2012-11-28 | 巴斯夫植物科学有限公司 | Rna介导的植物中基因表达的诱导 |
| EP2421972A2 (en) * | 2009-04-24 | 2012-02-29 | The Board of Regents of The University of Texas System | Modulation of gene expression using oligomers that target gene regions downstream of 3' untranslated regions |
| KR101722541B1 (ko) | 2009-05-06 | 2017-04-04 | 큐알엔에이, 인크. | Ｔｔｐ에 대한 천연 안티센스 전사체의 억제에 의한 트리스테트라프롤린 관련된 질환의 치료 |
| CN102459596B (zh) | 2009-05-06 | 2016-09-07 | 库尔纳公司 | 通过针对脂质转运和代谢基因的天然反义转录物的抑制治疗脂质转运和代谢基因相关疾病 |
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| WO2010135329A2 (en) | 2009-05-18 | 2010-11-25 | Curna, Inc. | Treatment of reprogramming factor related diseases by inhibition of natural antisense transcript to a reprogramming factor |
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| KR101704988B1 (ko) | 2009-05-28 | 2017-02-08 | 큐알엔에이, 인크. | 항바이러스 유전자에 대한 천연 안티센스 전사체의 억제에 의한 항바이러스 유전자 관련된 질환의 치료 |
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| AU2011200554B2 (en) | 2012-02-09 |
| WO2007086990A2 (en) | 2007-08-02 |
| AU2006336624A1 (en) | 2007-08-02 |
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