DK2624894T3 - Drivmekanisme til en lægemiddeldispenseringsanordning og lægemiddeldispenseringsanordning - Google Patents

Drivmekanisme til en lægemiddeldispenseringsanordning og lægemiddeldispenseringsanordning Download PDF

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Publication number
DK2624894T3
DK2624894T3 DK11764230.6T DK11764230T DK2624894T3 DK 2624894 T3 DK2624894 T3 DK 2624894T3 DK 11764230 T DK11764230 T DK 11764230T DK 2624894 T3 DK2624894 T3 DK 2624894T3
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Denmark
Prior art keywords
lead screw
screw
drive
guide
drive member
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DK11764230.6T
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English (en)
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David Aubrey Plumptre
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Sanofi Aventis Deutschland
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/31555—Mechanically operated dose setting member by purely axial movement of dose setting member, e.g. during setting or filling of a syringe
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3156—Mechanically operated dose setting member using volume steps only adjustable in discrete intervals, i.e. individually distinct intervals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
    • A61M5/31585—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159—Dose expelling manners
    • A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16H—GEARING
    • F16H25/00—Gearings comprising primarily only cams, cam-followers and screw-and-nut mechanisms
    • F16H25/18—Gearings comprising primarily only cams, cam-followers and screw-and-nut mechanisms for conveying or interconverting oscillating or reciprocating motions
    • F16H25/20—Screw mechanisms
    • F16H25/2015—Means specially adapted for stopping actuators in the end position; Position sensing means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2403—Ampoule inserted into the ampoule holder
    • A61M2005/2407—Ampoule inserted into the ampoule holder from the rear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M5/31515—Connection of piston with piston rod
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T74/00—Machine element or mechanism
    • Y10T74/18—Mechanical movements
    • Y10T74/18568—Reciprocating or oscillating to or from alternating rotary
    • Y10T74/18576—Reciprocating or oscillating to or from alternating rotary including screw and nut
    • Y10T74/18688—Limit stop

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Transmission Devices (AREA)

Claims (9)

1. Drivmekanisme til en lægemiddeldispenseringsanordning, der omfatter: - en ledeskrue (5), en ledeskruemøtrik (7) og en drivdel (8), der er på linje med en akse (4), der definerer en aksial retning og en modsat aksial retning, - hvor en kobling mellem ledeskruen (5) og ledeskruemøtrikken (7) åbner mulighed for en skruebevægelse af ledeskruen (5) i forhold til ledeskruemøtrikken (7) mindst i den aksiale retning, - hvor ledeskruen (5) er koblet med drivdelen (8), hvilken kobling frembringer en skruebevægelse af ledeskruen (5) i forhold til drivdelen (8), når drivdelen (8) bevæges i den aksiale retning i forhold til ledeskruen (5) , og koblingen tilsidesættes til forhindring af en skruebevægelse af ledeskruen (5) i forhold til drivdelen (8), når drivdelen (8) bevæges i den modsatte aksiale retning i forhold til ledeskruen (5), - et dispenseringsstoptræk (19) på ledeskruemøtrikken (7) og - et dispenseringsstoptræk (20) på drivdelen (8), - hvilke dispenseringsstoptræk (19, 20) interagerer og derved forhindrer frembringelsen af skruebevægelsen af ledeskruen (5), når drivdelen (8) nærmer sig en specificeret slutposition, der er kendetegnet ved, at dispenseringsstoptrækkene (19, 20) har tilsvarende kontaktflader (22), der er skrå på aksen (4).
2. Drivmekanisme ifølge krav 1, hvor dispenseringsstoptrækkene (19, 20) har tilsvarende endeflader (23), der hæmmer en rotation af drivdelen (8) i forhold til ledeskruemøtrikken (7) i mindst én retning.
3. Drivmekanisme ifølge et af kravene 1 til 2, hvor dispenseringsstoptrækket (19) på ledeskruemøtrikken (7) har form som en prisme eller en afkortet prisme.
4. Drivmekanisme ifølge et af kravene 1 til 3, hvor dispenseringsstoptrækkene (19, 20) styrer drivdelen (8) i forhold til ledeskruemøtrikken (7) i en skruebevægelse med den samme stigning som skruebevægelsen af ledeskruen (5) i forhold til drivdelen (8) .
5. Drivmekanisme ifølge et af kravene 1 til 4, der yderligere omfatter: et fleksibelt styretræk (15) på ledeskruen (5) og et skruegevind (18) på drivdelen (8), hvor koblingen af ledeskruen (5) med drivdelen (8) tilvejebringes af, at det fleksible styretræk (15) går i indgreb med skruegevindet (18), og hvor skruegevindet (18) har den samme stigning som skruebevægelsen af ledeskruen (5) i forhold til drivdelen (8).
6. Drivmekanisme ifølge et af kravene 1 til 5, der yderligere omfatter: stoptræk (17) på ledeskruen (5), hvilke stoptræk (17) hæmmer skruebevægelsen af ledeskruen (5), når drivdelen (8) bevæges i den modsatte aksiale retning i forhold til ledeskruen (5) .
7. Drivmekanisme ifølge et af kravene 1 til 6, hvor drivdelen (8) og ledeskruemøtrikken (7) er rotationslåst.
8. Drivmekanisme ifølge et af kravene 1 til 7, hvor dispenseringsstoptrækket (19) på ledeskruemøtrikken (7) er formet som en integreret del af ledeskruemøtrikken (7), og dispenseringsstoptrækket (20) på drivdelen (8) er formet som en integreret del af drivdelen (8).
9. Lægemiddeldispenseringsanordning, der omfatter: - en drivmekanisme ifølge et af kravene 1 til 8 og - et legeme (1) med en distal ende (2) og en proksimal ende (3), der er adskilt fra hinanden i retningen af aksen (4) .
DK11764230.6T 2010-10-06 2011-10-05 Drivmekanisme til en lægemiddeldispenseringsanordning og lægemiddeldispenseringsanordning DK2624894T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20100186736 EP2438951A1 (en) 2010-10-06 2010-10-06 Drive mechanism for a drug delivery device and drug delivery device
PCT/EP2011/067418 WO2012045794A1 (en) 2010-10-06 2011-10-05 Drive mechanism for a drug delivery device and drug delivery device

Publications (1)

Publication Number Publication Date
DK2624894T3 true DK2624894T3 (da) 2018-06-25

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US (1) US9072836B2 (da)
EP (2) EP2438951A1 (da)
JP (1) JP6042339B2 (da)
KR (1) KR101880027B1 (da)
CN (1) CN103228310B (da)
AR (1) AR083300A1 (da)
AU (1) AU2011311617B2 (da)
BR (1) BR112013006949B1 (da)
CA (1) CA2811953C (da)
DK (1) DK2624894T3 (da)
ES (1) ES2674594T3 (da)
HU (1) HUE037970T2 (da)
IL (1) IL225364B (da)
MX (1) MX339430B (da)
NZ (1) NZ609013A (da)
PL (1) PL2624894T3 (da)
RU (1) RU2577451C2 (da)
SG (1) SG188423A1 (da)
TR (1) TR201808737T4 (da)
TW (1) TWI538706B (da)
WO (1) WO2012045794A1 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108815645A (zh) * 2012-05-30 2018-11-16 赛诺菲-安万特德国有限公司 用于药物输送装置的活塞杆主体的轴承、活塞杆组合体和活塞杆主体

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6663602B2 (en) * 2000-06-16 2003-12-16 Novo Nordisk A/S Injection device
DE10237258B4 (de) 2002-08-14 2006-09-21 Tecpharma Licensing Ag Injektionsvorrichtung
GB0304823D0 (en) * 2003-03-03 2003-04-09 Dca Internat Ltd Improvements in and relating to a pen-type injector
JP2008532581A (ja) * 2005-02-22 2008-08-21 テクファーマ・ライセンシング・アクチェンゲゼルシャフト 精密な投薬量を設定する投薬量設定機構
US20090043264A1 (en) * 2005-04-24 2009-02-12 Novo Nordisk A/S Injection Device
DE102005023854B4 (de) * 2005-05-24 2020-12-17 Tecpharma Licensing Ag Dosiervorrichtung für eine Injektionsvorrichtung
DE102006038101A1 (de) * 2006-08-14 2008-02-21 Tecpharma Licensing Ag Injektionsvorrichtung mit Klauensicherung
EP1923085A1 (en) * 2006-11-17 2008-05-21 Sanofi-Aventis Deutschland GmbH Dosing and drive mechanism for drug delivery device
EP1923084A1 (en) * 2006-11-17 2008-05-21 Sanofi-Aventis Deutschland GmbH Dosing and drive mechanism for drug delivery device
US8647309B2 (en) * 2008-05-02 2014-02-11 Sanofi-Aventis Deutschland Gmbh Medication delivery device
CA2723260A1 (en) * 2008-05-02 2009-11-05 Sanofi-Aventis Deutschland Gmbh Medication delivery device
US8267900B2 (en) * 2008-05-02 2012-09-18 Sanofi-Aventis Deutschland Gmbh Medication delivery device
EP2201972A1 (en) * 2008-12-23 2010-06-30 Sanofi-Aventis Deutschland GmbH Fixed dose injection device with resettable drive mechanism

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Publication number Publication date
TWI538706B (zh) 2016-06-21
KR20130120476A (ko) 2013-11-04
US9072836B2 (en) 2015-07-07
WO2012045794A1 (en) 2012-04-12
EP2624894B1 (en) 2018-03-21
SG188423A1 (en) 2013-04-30
JP6042339B2 (ja) 2016-12-14
RU2013120298A (ru) 2014-11-20
EP2624894A1 (en) 2013-08-14
KR101880027B1 (ko) 2018-07-20
MX2013003665A (es) 2013-05-28
IL225364A0 (en) 2013-06-27
AU2011311617B2 (en) 2015-01-22
US20130211343A1 (en) 2013-08-15
HUE037970T2 (hu) 2018-09-28
EP2438951A1 (en) 2012-04-11
CN103228310A (zh) 2013-07-31
AR083300A1 (es) 2013-02-13
ES2674594T3 (es) 2018-07-02
CA2811953A1 (en) 2012-04-12
MX339430B (es) 2016-05-26
TW201231111A (en) 2012-08-01
JP2013539677A (ja) 2013-10-28
AU2011311617A1 (en) 2013-04-11
BR112013006949A2 (pt) 2016-07-26
RU2577451C2 (ru) 2016-03-20
TR201808737T4 (tr) 2018-07-23
BR112013006949B1 (pt) 2021-01-19
CA2811953C (en) 2018-07-31
IL225364B (en) 2018-10-31
NZ609013A (en) 2014-06-27
PL2624894T3 (pl) 2018-08-31
CN103228310B (zh) 2015-11-25

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