BR112013006949A2 - mecanismo de acionamento para um dispositivo de liberação controlada de fármaco e dispositivo de liberação controlada de fármaco - Google Patents

mecanismo de acionamento para um dispositivo de liberação controlada de fármaco e dispositivo de liberação controlada de fármaco

Info

Publication number
BR112013006949A2
BR112013006949A2 BR112013006949A BR112013006949A BR112013006949A2 BR 112013006949 A2 BR112013006949 A2 BR 112013006949A2 BR 112013006949 A BR112013006949 A BR 112013006949A BR 112013006949 A BR112013006949 A BR 112013006949A BR 112013006949 A2 BR112013006949 A2 BR 112013006949A2
Authority
BR
Brazil
Prior art keywords
lead screw
drug release
release device
drive member
controlled drug
Prior art date
Application number
BR112013006949A
Other languages
English (en)
Other versions
BR112013006949B1 (pt
Inventor
David Aubrey Plumptre
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of BR112013006949A2 publication Critical patent/BR112013006949A2/pt
Publication of BR112013006949B1 publication Critical patent/BR112013006949B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/31555—Mechanically operated dose setting member by purely axial movement of dose setting member, e.g. during setting or filling of a syringe
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3156—Mechanically operated dose setting member using volume steps only adjustable in discrete intervals, i.e. individually distinct intervals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
    • A61M5/31585—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159—Dose expelling manners
    • A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16H—GEARING
    • F16H25/00—Gearings comprising primarily only cams, cam-followers and screw-and-nut mechanisms
    • F16H25/18—Gearings comprising primarily only cams, cam-followers and screw-and-nut mechanisms for conveying or interconverting oscillating or reciprocating motions
    • F16H25/20—Screw mechanisms
    • F16H25/2015—Means specially adapted for stopping actuators in the end position; Position sensing means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2403—Ampoule inserted into the ampoule holder
    • A61M2005/2407—Ampoule inserted into the ampoule holder from the rear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M5/31515—Connection of piston with piston rod
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T74/00—Machine element or mechanism
    • Y10T74/18—Mechanical movements
    • Y10T74/18568—Reciprocating or oscillating to or from alternating rotary
    • Y10T74/18576—Reciprocating or oscillating to or from alternating rotary including screw and nut
    • Y10T74/18688—Limit stop

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Transmission Devices (AREA)

Abstract

mecanismo de acionamento para um dispositivo de liberação controlada de fármaco e dispositivo de liberação controlada de fármaco. a presente invenção refere-se a um parafuso de chumbo, uma porca para parafuso de chumbo (7) e um membro de acionamento (8) que são alinhados com um eixo geométrico que define uma direção axial e uma direção axial oposta. um acoplamento entre o parafuso de chumbo e a porca para parafuso de chumbo permite um movimento helicoidal do parafuso de chumbo com relação à porca para parafuso de chumbo pelo menos na direção axial. o parafuso de chumbo é acoplado com o membro de acionamento, sendo que o acoplamento gera um movimento helicoidal do parafuso de chumbo com relação ao membro de acionamento quando o membro de acionamento é movido na direção axial com relação ao parafuso de chumbo. um recurso de parada de dispensa (19) da porca para parafuso de chumbo e um recurso de parada de dispensa (20) do membro de acionamento impedem a geração do movimento helicoidal do parafuso de chumbo quando uma posição final especificada do membro de acionamento se aproxima.
BR112013006949-0A 2010-10-06 2011-10-05 mecanismo de acionamento para um dispositivo de liberação controlada de fármaco BR112013006949B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10186736.4 2010-10-06
EP20100186736 EP2438951A1 (en) 2010-10-06 2010-10-06 Drive mechanism for a drug delivery device and drug delivery device
PCT/EP2011/067418 WO2012045794A1 (en) 2010-10-06 2011-10-05 Drive mechanism for a drug delivery device and drug delivery device

Publications (2)

Publication Number Publication Date
BR112013006949A2 true BR112013006949A2 (pt) 2016-07-26
BR112013006949B1 BR112013006949B1 (pt) 2021-01-19

Family

ID=43607654

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013006949-0A BR112013006949B1 (pt) 2010-10-06 2011-10-05 mecanismo de acionamento para um dispositivo de liberação controlada de fármaco

Country Status (21)

Country Link
US (1) US9072836B2 (pt)
EP (2) EP2438951A1 (pt)
JP (1) JP6042339B2 (pt)
KR (1) KR101880027B1 (pt)
CN (1) CN103228310B (pt)
AR (1) AR083300A1 (pt)
AU (1) AU2011311617B2 (pt)
BR (1) BR112013006949B1 (pt)
CA (1) CA2811953C (pt)
DK (1) DK2624894T3 (pt)
ES (1) ES2674594T3 (pt)
HU (1) HUE037970T2 (pt)
IL (1) IL225364B (pt)
MX (1) MX339430B (pt)
NZ (1) NZ609013A (pt)
PL (1) PL2624894T3 (pt)
RU (1) RU2577451C2 (pt)
SG (1) SG188423A1 (pt)
TR (1) TR201808737T4 (pt)
TW (1) TWI538706B (pt)
WO (1) WO2012045794A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3622988B1 (en) 2012-05-30 2022-12-14 Sanofi-Aventis Deutschland GmbH Piston rod arrangement and a drug delivery device comprising such a piston rod assembly

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6663602B2 (en) * 2000-06-16 2003-12-16 Novo Nordisk A/S Injection device
DE10237258B4 (de) 2002-08-14 2006-09-21 Tecpharma Licensing Ag Injektionsvorrichtung
GB0304823D0 (en) * 2003-03-03 2003-04-09 Dca Internat Ltd Improvements in and relating to a pen-type injector
PL1855742T3 (pl) * 2005-02-22 2009-08-31 Tecpharma Licensing Ag Urządzenie dozujące do dokładnego odmierzania dawek produktu
EP1877121B1 (en) * 2005-04-24 2015-09-23 Novo Nordisk A/S Injection device
DE102005023823B4 (de) * 2005-05-24 2022-11-17 Tecpharma Licensing Ag Dosiervorrichtung für eine Injektionsvorrichtung und Injektionsvorrichtung mit einer solchen Dosiervorrichtung
DE102006038101A1 (de) * 2006-08-14 2008-02-21 Tecpharma Licensing Ag Injektionsvorrichtung mit Klauensicherung
EP1923084A1 (en) * 2006-11-17 2008-05-21 Sanofi-Aventis Deutschland GmbH Dosing and drive mechanism for drug delivery device
EP1923085A1 (en) * 2006-11-17 2008-05-21 Sanofi-Aventis Deutschland GmbH Dosing and drive mechanism for drug delivery device
US8647309B2 (en) * 2008-05-02 2014-02-11 Sanofi-Aventis Deutschland Gmbh Medication delivery device
US8267900B2 (en) * 2008-05-02 2012-09-18 Sanofi-Aventis Deutschland Gmbh Medication delivery device
MX2010011251A (es) * 2008-05-02 2010-11-12 Sanofi Aventis Deutschland Dispositivo de suministro de medicacion.
EP2201972A1 (en) * 2008-12-23 2010-06-30 Sanofi-Aventis Deutschland GmbH Fixed dose injection device with resettable drive mechanism

Also Published As

Publication number Publication date
AU2011311617B2 (en) 2015-01-22
EP2624894A1 (en) 2013-08-14
TWI538706B (zh) 2016-06-21
PL2624894T3 (pl) 2018-08-31
JP2013539677A (ja) 2013-10-28
US20130211343A1 (en) 2013-08-15
IL225364A0 (en) 2013-06-27
MX2013003665A (es) 2013-05-28
EP2438951A1 (en) 2012-04-11
CN103228310B (zh) 2015-11-25
CA2811953C (en) 2018-07-31
KR20130120476A (ko) 2013-11-04
IL225364B (en) 2018-10-31
DK2624894T3 (en) 2018-06-25
HUE037970T2 (hu) 2018-09-28
SG188423A1 (en) 2013-04-30
RU2577451C2 (ru) 2016-03-20
NZ609013A (en) 2014-06-27
AU2011311617A1 (en) 2013-04-11
KR101880027B1 (ko) 2018-07-20
US9072836B2 (en) 2015-07-07
AR083300A1 (es) 2013-02-13
EP2624894B1 (en) 2018-03-21
TR201808737T4 (tr) 2018-07-23
TW201231111A (en) 2012-08-01
BR112013006949B1 (pt) 2021-01-19
CN103228310A (zh) 2013-07-31
RU2013120298A (ru) 2014-11-20
WO2012045794A1 (en) 2012-04-12
ES2674594T3 (es) 2018-07-02
MX339430B (es) 2016-05-26
JP6042339B2 (ja) 2016-12-14
CA2811953A1 (en) 2012-04-12

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 05/10/2011, OBSERVADAS AS CONDICOES LEGAIS.