BR112012007206A2 - dispositivo de distribuição de fármacos - Google Patents

dispositivo de distribuição de fármacos

Info

Publication number
BR112012007206A2
BR112012007206A2 BR112012007206A BR112012007206A BR112012007206A2 BR 112012007206 A2 BR112012007206 A2 BR 112012007206A2 BR 112012007206 A BR112012007206 A BR 112012007206A BR 112012007206 A BR112012007206 A BR 112012007206A BR 112012007206 A2 BR112012007206 A2 BR 112012007206A2
Authority
BR
Brazil
Prior art keywords
drive element
delivery device
drug delivery
piston rod
dose
Prior art date
Application number
BR112012007206A
Other languages
English (en)
Inventor
Andrew Mark Lindsay
Catherine Anne Macdonald
Christopher Jones
David Plumptre
Garen Kouyoumjian
Robert Veasey
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Priority to BR122014012248A priority Critical patent/BR122014012248A2/pt
Publication of BR112012007206A2 publication Critical patent/BR112012007206A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
    • A61M5/31585—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A61M5/31543—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose piston rod reset means, i.e. means for causing or facilitating retraction of piston rod to its starting position during cartridge change
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/3157—Means providing feedback signals when administration is completed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/31573—Accuracy improving means
    • A61M5/31575—Accuracy improving means using scaling up or down transmissions, e.g. gearbox
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2403—Ampoule inserted into the ampoule holder
    • A61M2005/2407—Ampoule inserted into the ampoule holder from the rear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3125—Details specific display means, e.g. to indicate dose setting
    • A61M2005/3126—Specific display means related to dosing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/581—Means for facilitating use, e.g. by people with impaired vision by audible feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/582—Means for facilitating use, e.g. by people with impaired vision by tactile feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3146—Priming, e.g. purging, reducing backlash or clearance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/31555—Mechanically operated dose setting member by purely axial movement of dose setting member, e.g. during setting or filling of a syringe

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

dispositivo de distribuição de fármacos a presente invenção refere-se a um dispositivo de distribuição de fármacos (4) para distribuir uma ou mais doces de um farmaco. o dispositivo (4) compreende um elemento de acionamento (1) para acionar uma haste de pistão (5) e um elemento de dose (46) para atuar o elemento de acionamento (1). a haste de pistão (5) é acoplada ao elemento de acionamento (1) de modo que um movimento translacional relajtivo do elemento de acionamento (1) e da haste de pistão (5) seja ´permitido e um movimento rotacional relativo seja impedido. o elemento de acionamento (1) é configurado para ser acioonado pelo elemento nde dose (46) em torno do eixo geométrico longitudinal em uma primeira (110) e uma segunda direção rotacional (111) opostas uma à outra . a demais, proporcina-se um dispositivo de distribuição de fármacos (4), em que o elemento de acionamento elemento de acionamento (1) é inclinado pelo meio de inclinação (3) voltado para um estado estável.
BR112012007206A 2009-09-30 2010-09-29 dispositivo de distribuição de fármacos BR112012007206A2 (pt)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BR122014012248A BR122014012248A2 (pt) 2009-09-30 2010-09-29 dispositivo de fornecimento de fármaco reajustável

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09171732 2009-09-30
PCT/EP2010/064392 WO2011039203A2 (en) 2009-09-30 2010-09-29 Drug delivery device

Publications (1)

Publication Number Publication Date
BR112012007206A2 true BR112012007206A2 (pt) 2016-04-05

Family

ID=45024809

Family Applications (2)

Application Number Title Priority Date Filing Date
BR122014012248A BR122014012248A2 (pt) 2009-09-30 2010-09-29 dispositivo de fornecimento de fármaco reajustável
BR112012007206A BR112012007206A2 (pt) 2009-09-30 2010-09-29 dispositivo de distribuição de fármacos

Family Applications Before (1)

Application Number Title Priority Date Filing Date
BR122014012248A BR122014012248A2 (pt) 2009-09-30 2010-09-29 dispositivo de fornecimento de fármaco reajustável

Country Status (16)

Country Link
US (1) US9387294B2 (pt)
EP (1) EP2482883B1 (pt)
JP (1) JP5768050B2 (pt)
KR (1) KR20120092608A (pt)
CN (1) CN102639173B (pt)
AR (1) AR079004A1 (pt)
AU (1) AU2010303047B2 (pt)
BR (2) BR122014012248A2 (pt)
CA (1) CA2773203A1 (pt)
IL (1) IL218839A0 (pt)
MX (1) MX2012003814A (pt)
NZ (1) NZ599024A (pt)
RU (1) RU2552019C2 (pt)
TW (1) TW201127434A (pt)
WO (1) WO2011039203A2 (pt)
ZA (1) ZA201201565B (pt)

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US8939943B2 (en) 2011-01-26 2015-01-27 Kaleo, Inc. Medicament delivery device for administration of opioid antagonists including formulations for naloxone
US8627816B2 (en) 2011-02-28 2014-01-14 Intelliject, Inc. Medicament delivery device for administration of opioid antagonists including formulations for naloxone
US9084849B2 (en) 2011-01-26 2015-07-21 Kaleo, Inc. Medicament delivery devices for administration of a medicament within a prefilled syringe
TWI574708B (zh) * 2011-06-17 2017-03-21 賽諾菲阿凡提斯德意志有限公司 用於藥物遞送裝置的卡匣支撐器總成
CN103998082B (zh) * 2011-10-14 2016-11-16 赛诺菲-安万特德国有限公司 用于药物输送装置的组件
AU2012348406B2 (en) 2011-12-06 2015-05-07 Shl Medical Ag Medicament delivery device
US9370623B2 (en) 2011-12-08 2016-06-21 Sanofi-Aventis Deutschland Gmbh Drive assembly for a medication delivery device and medication delivery device comprising a drive assembly
US9751056B2 (en) 2012-01-23 2017-09-05 Merit Medical Systems, Inc. Mixing syringe
US8834449B2 (en) 2012-01-23 2014-09-16 Ikomed Technologies, Inc. Mixing syringe
US9522235B2 (en) 2012-05-22 2016-12-20 Kaleo, Inc. Devices and methods for delivering medicaments from a multi-chamber container
EP2890435B1 (en) * 2012-08-31 2020-03-04 Sanofi-Aventis Deutschland GmbH Drug delivery device
JP2015536164A (ja) * 2012-10-23 2015-12-21 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 薬物送達デバイスで使用されるカウンタシステム
GB201301046D0 (en) 2013-01-21 2013-03-06 Owen Mumford Ltd Dosing mechanism
EP2983769B1 (en) * 2013-04-10 2017-05-17 Sanofi Drive mechanism of a drug delivery device
WO2014166735A1 (en) * 2013-04-12 2014-10-16 Carebay Europe Ltd Medicament delivery device
EP3041534A1 (en) * 2013-09-03 2016-07-13 Sanofi Drive mechanism and injection device herewith
EP4360675A3 (en) * 2013-11-22 2024-07-03 Sanofi-Aventis Deutschland GmbH Drug delivery device with dose knob clutch
CH707217A2 (de) 2014-02-26 2014-04-30 Tecpharma Licensing Ag Injektionsvorrichtung zur Verabreichung eines fluiden Produkts.
US9517307B2 (en) 2014-07-18 2016-12-13 Kaleo, Inc. Devices and methods for delivering opioid antagonists including formulations for naloxone
US10695495B2 (en) 2015-03-24 2020-06-30 Kaleo, Inc. Devices and methods for delivering a lyophilized medicament
AU2016287571C1 (en) 2015-06-30 2021-12-23 Kaleo, Inc. Auto-injectors for administration of a medicament within a prefilled syringe
AU2017379094B2 (en) 2016-12-23 2023-08-24 Kaleo, Inc. Medicament delivery device and methods for delivering drugs to infants and children
US11426526B2 (en) 2017-02-13 2022-08-30 Tata Elxsi Limited Dispensing device
TWI662976B (zh) * 2018-09-07 2019-06-21 群康生技股份有限公司 注射器的推進裝置
JP6962623B2 (ja) 2018-09-07 2021-11-05 群康生技股▲分▼有限公司 注射器のための推進装置
WO2021030210A1 (en) 2019-08-09 2021-02-18 Kaleo, Inc. Devices and methods for delivery of substances within a prefilled syringe
CN117462795B (zh) * 2023-12-26 2024-03-08 四川省医学科学院·四川省人民医院 一种胰岛素笔

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GB9226423D0 (en) 1992-12-18 1993-02-10 Sams Bernard Incrementing mechanisms
US6936032B1 (en) * 1999-08-05 2005-08-30 Becton, Dickinson And Company Medication delivery pen
US6663602B2 (en) 2000-06-16 2003-12-16 Novo Nordisk A/S Injection device
EP2258425B1 (en) * 2001-05-16 2013-01-30 Eli Lilly and Company Medication injector apparatus
EP1819384A1 (en) * 2004-10-14 2007-08-22 Novo Nordisk A/S Syringe with dosis mechanism
DE102005008280B3 (de) * 2005-02-23 2006-07-13 Tecpharma Licensing Ag Verabreichungsvorrichtung mit Anzeigetrommel
EP1923083A1 (en) 2006-11-17 2008-05-21 Sanofi-Aventis Deutschland GmbH Drive mechanisms for use in drug delivery devices
EP1923085A1 (en) 2006-11-17 2008-05-21 Sanofi-Aventis Deutschland GmbH Dosing and drive mechanism for drug delivery device
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DK2254624T3 (da) * 2008-02-12 2014-10-06 Shl Group Ab Automatisk injektor

Also Published As

Publication number Publication date
WO2011039203A3 (en) 2011-06-23
AR079004A1 (es) 2011-12-21
TW201127434A (en) 2011-08-16
BR122014012248A2 (pt) 2016-04-19
JP2013506443A (ja) 2013-02-28
AU2010303047A1 (en) 2012-04-19
AU2010303047B2 (en) 2015-05-21
KR20120092608A (ko) 2012-08-21
IL218839A0 (en) 2012-06-28
RU2552019C2 (ru) 2015-06-10
CN102639173A (zh) 2012-08-15
NZ599024A (en) 2014-03-28
CN102639173B (zh) 2014-11-05
RU2012117205A (ru) 2013-11-10
CA2773203A1 (en) 2011-04-07
JP5768050B2 (ja) 2015-08-26
US9387294B2 (en) 2016-07-12
US20120310168A1 (en) 2012-12-06
MX2012003814A (es) 2012-05-08
WO2011039203A2 (en) 2011-04-07
ZA201201565B (en) 2012-11-28
EP2482883B1 (en) 2017-01-18
EP2482883A2 (en) 2012-08-08

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Legal Events

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2384 DE 13-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.