DK2594580T3 - Fremgangsmåde til diagnosticering af infektioner med Propionibacterium-bakterier - Google Patents
Fremgangsmåde til diagnosticering af infektioner med Propionibacterium-bakterier Download PDFInfo
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- DK2594580T3 DK2594580T3 DK11306495.0T DK11306495T DK2594580T3 DK 2594580 T3 DK2594580 T3 DK 2594580T3 DK 11306495 T DK11306495 T DK 11306495T DK 2594580 T3 DK2594580 T3 DK 2594580T3
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Peptides Or Proteins (AREA)
Claims (12)
1. In wfro-fremgangsmåde til bestemmelse af, om et individ er inficeret med en bakterie af Propionibacterium-arten, hvor infektionen er en proteseinfektion, omfattende: - at detektere antistoffer, der er rettet mod mindst et protein fra sekvens SEQ ID NO: 2 i en biologisk prøve fra individet, hvor den biologiske prøve er udvalgt fra gruppen bestående af blod, serum, plasma, slimhindeassocieret lymfoidt væv, cerebrospinaivæske, ledvæske, pleuravæske, spyt og urin, og - derfra at udlede, at individet er inficeret med en bakterie af Propionibacteri-um- arten.
2. Fremgangsmåde ifølge krav 1, hvor bakterien er udvalgt fra gruppen bestående af P. aenes, P. avidum, P. granulosum og P. propionieum.
3. Fremgangsmåde ifølge krav 1 eller 2, hvor antistofferne er IgG.
4. Fremgangsmåde ifølge et hvilket som helst af kravene 1 til 3, hvor et proteseled, der er implanteret i individet, er inficeret med bakterien.
5. Fremgangsmåde ifølge krav 4, hvor protesen udvælges fra gruppen bestående af et knæled, et skulderled og et hofteled.
6. Fremgangsmåde ifølge et hvilket som helst af kravene 1 til 5, hvor detekteringen af antistoffer rettet mod mindst et protein fra sekvens SEQ ID NO: 2 omfatter at bringe den biologiske prøve i kontakt med mindst et protein fra sekvens SEQ ID NO: 2.
7. Fremgangsmåde ifølge et hvilket som helst af kravene 1 til 6, hvor individet er i behandling med antibiotika.
8. Anvendelse af mindst et protein fra sekvens SEQ ID NO: 2 til in vitro-diagnostik af infektion med en bakterie af Propionibacterium-arten, hvor infektionen er en proteseinfektion.
9. Kit til diagnosticering af en infektion med en bakterie af Propionibacterium-arten, omfattende et protein fra sekvens SEQ ID NO: 2 og et protein fra sekvens SEQ ID NO: 4, SEQ ID NO: 6 eller SEQ ID NO: 8.
10. Kit ifølge krav 9, hvor kittet yderligere omfatter: mindst et protein fra sekvens SEQ ID NO: 32, SEQ ID NO: 34, SEQ ID NO: 36, SEQ ID NO: 38, SEQ ID NO: 40, SEQ ID NO: 42 eller SEQ ID NO: 44.
11. Kit ifølge krav 9 eller 10, hvor kittet yderligere omfatter: mindst et protein fra sekvens SEQ ID NO: 46, SEQ ID NO: 48, SEQ ID NO: 50 eller SEQ ID NO: 52.
12. Kit ifølge et hvilket som helst af kravene 10 til 11, hvor kittet yderligere omfatter mindst et protein fra sekvens SEQ ID NO: 54 eller SEQ ID NO: 56.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11306495.0A EP2594580B1 (en) | 2011-11-15 | 2011-11-15 | Method for diagnosing propionibacterium bacteria infections |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2594580T3 true DK2594580T3 (da) | 2016-08-15 |
Family
ID=45349431
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK11306495.0T DK2594580T3 (da) | 2011-11-15 | 2011-11-15 | Fremgangsmåde til diagnosticering af infektioner med Propionibacterium-bakterier |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US9528997B2 (da) |
| EP (2) | EP2594580B1 (da) |
| DK (1) | DK2594580T3 (da) |
| ES (1) | ES2584982T3 (da) |
| PT (1) | PT2594580T (da) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017217744A1 (ko) * | 2016-06-13 | 2017-12-21 | (주)이앤에스헬스케어 | 파지 디스플레이 기술을 이용한 여드름 균에 특이적으로 결합하는 인간 항체 및 이의 용도 |
| JP6916216B2 (ja) | 2016-06-13 | 2021-08-11 | イー アンド エス ヘルスケア カンパニー リミテッド | ファージディスプレイ技術を用いたにきび菌に特異的に結合するヒト抗体およびその用途 |
| CN110872632A (zh) * | 2018-08-30 | 2020-03-10 | 深圳华大生命科学研究院 | 咽颊炎链球菌的特异基因序列、其检测引物及其应用 |
| KR102151133B1 (ko) * | 2019-12-27 | 2020-09-02 | 주식회사 인투앱 | 프로피오니박테리움 아크네스에 특이적으로 결합하는 신규한 항체 및 이의 용도 |
| WO2024231727A1 (en) | 2023-05-05 | 2024-11-14 | Sanofi | Compositions for use in treatment of acne |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003033515A1 (en) * | 2001-10-15 | 2003-04-24 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of acne vulgaris |
| FR2945125B1 (fr) | 2009-05-04 | 2013-07-19 | Ingen Biosciences | Methode de diagnostic des infections a propionibacterium acnes |
-
2011
- 2011-11-15 EP EP11306495.0A patent/EP2594580B1/en not_active Not-in-force
- 2011-11-15 ES ES11306495.0T patent/ES2584982T3/es active Active
- 2011-11-15 EP EP15195447.6A patent/EP3002292A1/en not_active Withdrawn
- 2011-11-15 PT PT113064950T patent/PT2594580T/pt unknown
- 2011-11-15 DK DK11306495.0T patent/DK2594580T3/da active
-
2012
- 2012-11-14 US US13/676,597 patent/US9528997B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20130123132A1 (en) | 2013-05-16 |
| US9528997B2 (en) | 2016-12-27 |
| EP2594580A1 (en) | 2013-05-22 |
| EP3002292A1 (en) | 2016-04-06 |
| EP2594580B1 (en) | 2016-05-18 |
| PT2594580T (pt) | 2016-07-29 |
| ES2584982T3 (es) | 2016-09-30 |
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