DK2560738T3 - Simpel fremgangsmåde til samtidig fjernelse af flere urenheder fra dyrkningssupernatanter til ultralave niveauer - Google Patents

Simpel fremgangsmåde til samtidig fjernelse af flere urenheder fra dyrkningssupernatanter til ultralave niveauer Download PDF

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Publication number
DK2560738T3
DK2560738T3 DK10850408.5T DK10850408T DK2560738T3 DK 2560738 T3 DK2560738 T3 DK 2560738T3 DK 10850408 T DK10850408 T DK 10850408T DK 2560738 T3 DK2560738 T3 DK 2560738T3
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DK
Denmark
Prior art keywords
ultrala
cultural
pollutants
levels
simple procedure
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DK10850408.5T
Other languages
English (en)
Inventor
Andrew Lees
Jayant Joshi
Original Assignee
Serum Inst India Ltd
Fina Biosolutions Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Serum Inst India Ltd, Fina Biosolutions Llc filed Critical Serum Inst India Ltd
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Publication of DK2560738T3 publication Critical patent/DK2560738T3/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/505—Erythropoietin [EPO]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • B01D15/424—Elution mode
    • B01D15/426—Specific type of solvent
DK10850408.5T 2010-04-23 2010-12-20 Simpel fremgangsmåde til samtidig fjernelse af flere urenheder fra dyrkningssupernatanter til ultralave niveauer DK2560738T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32723810P 2010-04-23 2010-04-23
PCT/US2010/061313 WO2011133191A1 (en) 2010-04-23 2010-12-20 Simple method for simultaneous removal of multiple impurities from culture supernatants to ultralow levels

Publications (1)

Publication Number Publication Date
DK2560738T3 true DK2560738T3 (da) 2019-08-26

Family

ID=44816339

Family Applications (1)

Application Number Title Priority Date Filing Date
DK10850408.5T DK2560738T3 (da) 2010-04-23 2010-12-20 Simpel fremgangsmåde til samtidig fjernelse af flere urenheder fra dyrkningssupernatanter til ultralave niveauer

Country Status (8)

Country Link
US (1) US8383783B2 (da)
EP (1) EP2560738B8 (da)
AU (1) AU2010351576B2 (da)
CA (1) CA2797040C (da)
DK (1) DK2560738T3 (da)
ES (1) ES2743156T3 (da)
NZ (1) NZ602971A (da)
WO (1) WO2011133191A1 (da)

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NZ602971A (en) 2010-04-23 2014-11-28 Serum Inst India Ltd Simple method for simultaneous removal of multiple impurities from culture supernatants to ultralow levels
CN102532254B (zh) 2010-12-24 2015-06-24 武汉禾元生物科技股份有限公司 一种从水稻种子中分离纯化重组人血清白蛋白的方法
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CN102633897B (zh) * 2012-04-23 2014-04-23 成都欧林生物科技股份有限公司 b型流感嗜血杆菌荚膜多糖纯化工艺
CN103880947B (zh) * 2012-12-21 2016-01-13 武汉禾元生物科技股份有限公司 一种分离纯化高纯度重组人血清白蛋白的层析方法
US9782468B2 (en) 2013-05-20 2017-10-10 Shantha Biotechnics Private Limited Purification of polysaccharide protein conjugates
CN104707358A (zh) * 2013-12-13 2015-06-17 中国科学院大连化学物理研究所 一种新型双水相高速逆流色谱
WO2015117093A1 (en) 2014-01-31 2015-08-06 Fina Biosolutions, Llc Expression and purification of crm197 and related proteins
CN105349272B (zh) * 2015-11-17 2018-09-07 港龙生物技术（深圳）有限公司 一种用于微量移液针的清洗剂及其配制方法和使用方法
US10626376B2 (en) * 2016-11-14 2020-04-21 St. Jude Children's Research Hospital Method for isolating and purifying adeno-associated virus particles using salt
JP2020507371A (ja) * 2017-01-30 2020-03-12 リジェネロン・ファーマシューティカルズ・インコーポレイテッドＲｅｇｅｎｅｒｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． クロマトグラフィーにおけるバイオバーデンを低減するための組成物および方法
US11174284B2 (en) * 2017-04-04 2021-11-16 Scarab Genomics, Llc Purification of CRM 197 from bacteria
US20210070890A1 (en) 2019-09-06 2021-03-11 Serum Institute Of India Private Limited Method for obtaining purified bacterial polysaccharides
MX2022004817A (es) * 2019-10-22 2022-06-16 Genzyme Corp Monitorizacion de productos en linea en biofabricacion continua integrada.
CN111778232B (zh) * 2020-07-10 2022-03-11 江苏尤里卡生物科技有限公司 一种人尿激酶原料精制过程中去除内毒素的方法
DE102020214647A1 (de) 2020-11-20 2022-05-25 DIL Deutsches Institut für Lebensmitteltechnik e.V. Anthocyanhaltiges Extraktpulver und Verfahren zur Herstellung

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NZ602971A (en) 2010-04-23 2014-11-28 Serum Inst India Ltd Simple method for simultaneous removal of multiple impurities from culture supernatants to ultralow levels

Also Published As

Publication number Publication date
AU2010351576B2 (en) 2014-08-14
CA2797040A1 (en) 2011-10-27
US20110263834A1 (en) 2011-10-27
US8383783B2 (en) 2013-02-26
AU2010351576A1 (en) 2012-11-08
WO2011133191A1 (en) 2011-10-27
EP2560738B1 (en) 2019-07-24
NZ602971A (en) 2014-11-28
EP2560738A1 (en) 2013-02-27
ES2743156T3 (es) 2020-02-18
EP2560738B8 (en) 2019-09-25
CA2797040C (en) 2014-07-08
EP2560738A4 (en) 2014-10-08

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