DK2558118T3 - Krydsbeskyttende vaccine mod reproduktions- og respirationssyndromvirus hos svin - Google Patents

Krydsbeskyttende vaccine mod reproduktions- og respirationssyndromvirus hos svin Download PDF

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Publication number
DK2558118T3
DK2558118T3 DK11714556.5T DK11714556T DK2558118T3 DK 2558118 T3 DK2558118 T3 DK 2558118T3 DK 11714556 T DK11714556 T DK 11714556T DK 2558118 T3 DK2558118 T3 DK 2558118T3
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DK
Denmark
Prior art keywords
respiratory syndrome
vaccine against
syndrome virus
protective vaccine
animal protective
Prior art date
Application number
DK11714556.5T
Other languages
English (en)
Inventor
Hans Nauwynck
Peter Delputte
Marc Geldhof
Original Assignee
Univ Gent
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Publication date
Application filed by Univ Gent filed Critical Univ Gent
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Publication of DK2558118T3 publication Critical patent/DK2558118T3/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5252Virus inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/10011Arteriviridae
    • C12N2770/10021Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/10011Arteriviridae
    • C12N2770/10022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/10011Arteriviridae
    • C12N2770/10034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/10011Arteriviridae
    • C12N2770/10061Methods of inactivation or attenuation
    • C12N2770/10064Methods of inactivation or attenuation by serial passage
DK11714556.5T 2010-04-16 2011-04-14 Krydsbeskyttende vaccine mod reproduktions- og respirationssyndromvirus hos svin DK2558118T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10160139 2010-04-16
PCT/EP2011/055941 WO2011128415A1 (en) 2010-04-16 2011-04-14 Cross-protecting vaccine for porcine reproductive and respiratory syndrome virus

Publications (1)

Publication Number Publication Date
DK2558118T3 true DK2558118T3 (da) 2019-08-26

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
DK11714556.5T DK2558118T3 (da) 2010-04-16 2011-04-14 Krydsbeskyttende vaccine mod reproduktions- og respirationssyndromvirus hos svin

Country Status (4)

Country Link
EP (1) EP2558118B1 (da)
DK (1) DK2558118T3 (da)
ES (1) ES2742262T3 (da)
WO (1) WO2011128415A1 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0839912A1 (en) 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
EP1157121B1 (en) 1999-03-08 2013-04-24 Boehringer Ingelheim Vetmedica GmbH Prrsv replicon
PT2251419E (pt) 1999-04-22 2012-09-03 Us Agriculture Vacina contra a síndrome reprodutiva e respiratória porcina com base no isolado ja-142
MXPA06015105A (es) 2004-06-18 2007-03-26 Univ Minnesota Identificacion de organismos viralmente infectados y vacunados.
HUE031018T2 (hu) 2005-06-24 2017-06-28 Univ Minnesota PRRS vírusok, fertõzõ klónok, ezek mutánsai és alkalmazási eljárások
AR078253A1 (es) 2009-09-02 2011-10-26 Boehringer Ingelheim Vetmed Metodos para reducir la actividad antivirica en composiciones pcv-2 y composiciones pcv-2 con mejor inmunogenicidad
AU2012217170B2 (en) 2011-02-17 2016-07-28 Boehringer Ingelheim Vetmedica Gmbh Commercial scale process for production of PRRSV
ES2550258T3 (es) 2011-02-17 2015-11-05 Boehringer Ingelheim Vetmedica Gmbh Nueva cepa del PRRSV europea
US9187731B2 (en) 2011-07-29 2015-11-17 Boehringer Ingelheim Vetmedica Gmbh PRRS virus inducing type I interferon in susceptible cells
US9315781B2 (en) 2011-07-29 2016-04-19 Boehringer Ingelheim Vetmedica Gmbh Infectious CDNA clone of european PRRS virus and uses thereof
EP2968513A2 (en) 2013-03-15 2016-01-20 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome virus, compositions, vaccine and methods of use
JP6886291B2 (ja) 2013-12-20 2021-06-16 ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハーBoehringer Ingelheim Vetmedica GmbH PRRSウイルス変異株、ヨーロッパ型PRRSウイルスcDNAクローンおよびそれらの使用
CN108707587B (zh) * 2018-05-24 2022-04-05 北京世纪元亨动物防疫技术有限公司 一株欧洲型猪繁殖与呼吸综合征病毒株及其应用
US20220241393A1 (en) * 2019-08-29 2022-08-04 ELANCO US, Inc. Porcine reproductive and respiratory syndrome vaccine virus

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE118352T1 (de) 1991-06-06 1995-03-15 Stichting Centr Diergeneeskund Erreger der mysteriösen schweinekrankheit,impfstoff-zusammensetzungen und diagnose kits.
ES2074950B1 (es) * 1993-09-17 1996-03-16 Iberica Cyanamid Vacuna para la prevencion de la enfermedad reproductiva y respiratoria de la cerda.
PT676467E (pt) * 1994-04-11 2002-02-28 Akzo Nobel Nv Estirpes europeias de vacina do virus do sindroma reprodutivo e respiratorio porcino (prrsv)
JP2008526921A (ja) * 2005-01-13 2008-07-24 ベーリンガー インゲルハイム フェトメディカ ゲゼルシャフト ミット ベシュレンクテル ハフツング 改善されたprrsワクチン
WO2009106629A1 (en) 2008-02-29 2009-09-03 Universiteit Gent Viral inactivation process

Also Published As

Publication number Publication date
EP2558118A1 (en) 2013-02-20
WO2011128415A1 (en) 2011-10-20
ES2742262T3 (es) 2020-02-13
EP2558118B1 (en) 2019-06-05

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