DK2516433T3 - Substituerede n-(1h-indazol-4-yl)imidazo[1,2-a]pyridin-3-carboxamidforbindelser som cfms-inhibitorer - Google Patents
Substituerede n-(1h-indazol-4-yl)imidazo[1,2-a]pyridin-3-carboxamidforbindelser som cfms-inhibitorerInfo
- Publication number
- DK2516433T3 DK2516433T3 DK10798683.8T DK10798683T DK2516433T3 DK 2516433 T3 DK2516433 T3 DK 2516433T3 DK 10798683 T DK10798683 T DK 10798683T DK 2516433 T3 DK2516433 T3 DK 2516433T3
- Authority
- DK
- Denmark
- Prior art keywords
- indazol
- imidazo
- pyridin
- substituted
- carboxamide compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28872909P | 2009-12-21 | 2009-12-21 | |
| PCT/US2010/061341 WO2011079076A1 (en) | 2009-12-21 | 2010-12-20 | Substituted n-(1h-indazol-4-yl)imidazo[1, 2-a]pyridine-3- carboxamide compounds as cfms inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2516433T3 true DK2516433T3 (da) | 2014-08-11 |
Family
ID=43568700
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK10798683.8T DK2516433T3 (da) | 2009-12-21 | 2010-12-20 | Substituerede n-(1h-indazol-4-yl)imidazo[1,2-a]pyridin-3-carboxamidforbindelser som cfms-inhibitorer |
Country Status (32)
| Country | Link |
|---|---|
| US (1) | US8841455B2 (da) |
| EP (1) | EP2516433B1 (da) |
| JP (2) | JP5739448B2 (da) |
| KR (1) | KR101779630B1 (da) |
| CN (1) | CN102822170B (da) |
| AR (1) | AR079541A1 (da) |
| AU (1) | AU2010333752B2 (da) |
| BR (1) | BR112012017123B1 (da) |
| CA (1) | CA2785338C (da) |
| CL (1) | CL2012001699A1 (da) |
| CO (1) | CO6561821A2 (da) |
| CR (1) | CR20120389A (da) |
| DK (1) | DK2516433T3 (da) |
| ES (1) | ES2494590T3 (da) |
| HK (1) | HK1176928A1 (da) |
| HR (1) | HRP20140770T1 (da) |
| IL (1) | IL220544A (da) |
| ME (1) | ME01894B (da) |
| MX (1) | MX2012007329A (da) |
| MY (1) | MY163791A (da) |
| NZ (1) | NZ601376A (da) |
| PL (1) | PL2516433T3 (da) |
| PT (1) | PT2516433E (da) |
| RS (1) | RS53500B1 (da) |
| RU (1) | RU2562977C2 (da) |
| SG (1) | SG181861A1 (da) |
| SI (1) | SI2516433T1 (da) |
| SM (1) | SMT201400142B (da) |
| TW (1) | TWI471326B (da) |
| UA (1) | UA108222C2 (da) |
| WO (1) | WO2011079076A1 (da) |
| ZA (1) | ZA201205505B (da) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2987487T3 (da) | 2009-08-10 | 2020-12-07 | Samumed Llc | Indazolinhibitorer af wnt-signalvejen og terapeutiske anvendelser deraf |
| DK3001903T3 (da) | 2009-12-21 | 2017-12-18 | Samumed Llc | 1h-pyrazolo[3,4-?]pyridiner og terapeutiske anvendelser deraf |
| RU2562977C2 (ru) * | 2009-12-21 | 2015-09-10 | Эррэй Биофарма Инк. | СОЕДИНЕНИЯ ЗАМЕЩЕННОГО N-(1Н-ИНДАЗОЛ-4-ИЛ)ИМИДАЗОЛ[1,2-a]ПИРИДИН-3-КАРБОКСАМИДА КАК ИНГИБИТОРЫ cFMS |
| CA3027814A1 (en) | 2010-12-13 | 2012-06-21 | Array Biopharma Inc. | Substituted n-(1h-indazol-4-yl)imidazo[1,2-a]pyridine-3-carboxamide compounds as intermediates for type iii receptor tyrosine kinase inhibitors |
| AU2012308570B2 (en) | 2011-09-14 | 2016-11-10 | Samumed, Llc | Indazole-3-carboxamides and their use as Wnt/b-catenin signaling pathway inhibitors |
| PH12017500997A1 (en) | 2012-04-04 | 2018-02-19 | Samumed Llc | Indazole inhibitors of the wnt signal pathway and therapeutic uses thereof |
| EP2844249A4 (en) * | 2012-05-02 | 2016-03-09 | Univ Kansas State | MACROCYCLIC AND PEPTIDOMIMETIC COMPOUNDS AS VIRUZIDES AGAINST 3C OR 3C LIKE PROTEASES OF PICORNIVERS, CALICIVIRES AND CORONA VIRUSES |
| DK2770994T3 (da) | 2012-05-04 | 2019-11-11 | Samumed Llc | 1h-pyrazolo[3,4-b]pyridiner og terapeutiske anvendelser deraf |
| CN105120862A (zh) | 2013-01-08 | 2015-12-02 | 萨穆梅德有限公司 | Wnt信号途径的3-(苯并咪唑-2-基)-吲唑抑制剂及其治疗应用 |
| KR101756934B1 (ko) | 2014-07-08 | 2017-07-12 | 연세대학교 산학협력단 | 피롤로[1,2-a]피라진 유도체, 이의 약학적으로 허용가능한 염, 이들 화합물의 제조방법 및 이를 유효성분으로 함유하는 골다공증 치료 또는 예방용 약학조성물 |
| WO2016040188A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 3-(3h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof |
| WO2016040184A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 3-(3h-imidazo[4,5-b]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof |
| WO2016040182A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 2-(1h-indazol-3-yl)-1h-imidazo[4,5-c]pyridine and therapeutic uses thereof |
| WO2016040181A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof |
| WO2016040180A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 3-(1h-benzo[d]imidazol-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof |
| WO2016040193A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridine and therapeutic uses thereof |
| WO2016040185A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 2-(1h-indazol-3-yl)-3h-imidazo[4,5-b]pyridine and therapeutic uses thereof |
| WO2016040190A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 3-(3h-imidazo[4,5-b]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridine and therapeutic uses thereof |
| CA2969341C (en) | 2014-12-22 | 2023-07-04 | Five Prime Therapeutics, Inc. | Anti-csf1r antibodies for treating pvns |
| CN204833440U (zh) | 2015-07-29 | 2015-12-02 | 山东新北洋信息技术股份有限公司 | 识读组件及纸币清分机 |
| WO2017023980A1 (en) | 2015-08-03 | 2017-02-09 | Samumed, Llc. | 3-(1h-pyrrolo[2,3-b]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridines and therapeutic uses thereof |
| US10463651B2 (en) | 2015-08-03 | 2019-11-05 | Samumed, Llc | 3-(1H-pyrrolo[3,2-C]pyridin-2-YL)-1H-indazoles and therapeutic uses thereof |
| WO2017023972A1 (en) | 2015-08-03 | 2017-02-09 | Samumed, Llc. | 3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof |
| US10226448B2 (en) | 2015-08-03 | 2019-03-12 | Samumed, Llc | 3-(1H-pyrrolo[3,2-C]pyridin-2-yl)-1H-pyrazolo[3,4-B]pyridines and therapeutic uses thereof |
| US10392383B2 (en) | 2015-08-03 | 2019-08-27 | Samumed, Llc | 3-(1H-benzo[d]imidazol-2-yl)-1H-pyrazolo[4,3-b]pyridines and therapeutic uses thereof |
| US10226453B2 (en) | 2015-08-03 | 2019-03-12 | Samumed, Llc | 3-(1H-indol-2-yl)-1H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof |
| WO2017024004A1 (en) | 2015-08-03 | 2017-02-09 | Samumed, Llc. | 3-(1h-pyrrolo[2,3-b]pyridin-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof |
| WO2017024015A1 (en) | 2015-08-03 | 2017-02-09 | Samumed, Llc. | 3-(3h-imidazo[4,5-b]pyridin-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof |
| US10188634B2 (en) | 2015-08-03 | 2019-01-29 | Samumed, Llc | 3-(3H-imidazo[4,5-C]pyridin-2-yl)-1 H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof |
| US10383861B2 (en) | 2015-08-03 | 2019-08-20 | Sammumed, LLC | 3-(1H-pyrrolo[2,3-C]pyridin-2-yl)-1H-pyrazolo[3,4-C]pyridines and therapeutic uses thereof |
| US10206908B2 (en) | 2015-08-03 | 2019-02-19 | Samumed, Llc | 3-(1H-pyrrolo[3,2-C]pyridin-2-YL)-1H-pyrazolo[3,4-C]pyridines and therapeutic uses thereof |
| US10231956B2 (en) | 2015-08-03 | 2019-03-19 | Samumed, Llc | 3-(1H-pyrrolo[3,2-C]pyridin-2-YL)-1 H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof |
| US10285983B2 (en) | 2015-08-03 | 2019-05-14 | Samumed, Llc | 3-(1H-pyrrolo[2,3-B]pyridin-2-yl)-1H-pyrazolo[3,4-B] pyridines and therapeutic uses thereof |
| US10604512B2 (en) | 2015-08-03 | 2020-03-31 | Samumed, Llc | 3-(1H-indol-2-yl)-1H-indazoles and therapeutic uses thereof |
| WO2017024026A1 (en) | 2015-08-03 | 2017-02-09 | Samumed, Llc | 3-(1h-indol-2-yl)-1h-pyrazolo[3,4-c]pyridines and therapeutic uses thereof |
| WO2017024021A1 (en) | 2015-08-03 | 2017-02-09 | Samumed, Llc | 3-(1h-pyrrolo[2,3-b]pyridin-2-yl)-1h-indazoles and therapeutic uses thereof |
| US10519169B2 (en) | 2015-08-03 | 2019-12-31 | Samumed, Llc | 3-(1H-pyrrolo[2,3-C]pyridin-2-yl)-1 H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof |
| CA3004297A1 (en) | 2015-11-06 | 2017-05-11 | Samumed, Llc | 2-(1h-indazol-3-yl)-3h-imidazo[4,5-c]pyridines and their anti-inflammatory uses thereof |
| PL3464285T3 (pl) | 2016-06-01 | 2023-02-06 | Biosplice Therapeutics, Inc. | Sposób wytwarzania n-(5-(3-(7-(3-fluorofenylo)-3h-imidazo[4,5-c]pirydyn-2-ylo)-1h-indazol-5-ilo)pirydyn-3-ylo)-3-metylobutanoamidu |
| JP2019535672A (ja) | 2016-10-21 | 2019-12-12 | サミュメッド リミテッド ライアビリティ カンパニー | インダゾール−３−カルボキサミドの使用方法およびｗｎｔ／β−カテニンシグナル伝達経路阻害剤としてのそれらの使用 |
| WO2018083635A2 (en) | 2016-11-04 | 2018-05-11 | Auckland Uniservices Limited | Tricyclic heterocyclic derivatives and uses thereof |
| MA46696A (fr) | 2016-11-07 | 2019-09-11 | Samumed Llc | Formulations injectables à dose unique prêtes à l'emploi |
| CN110573500B (zh) * | 2017-05-24 | 2020-12-08 | 上海和誉生物医药科技有限公司 | N-(氮杂芳基)环内酰胺-1-甲酰胺衍生物及其制备方法和应用 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3952101A (en) | 1975-04-14 | 1976-04-20 | Smithkline Corporation | α-Amino methyl-5-hydroxy-2-pyridinemethanols |
| AU2001264932A1 (en) * | 2000-05-26 | 2001-12-11 | Neurogen Corporation | Oxo-imidazopyrimidine-carboxamides and their use as gaba brain receptor ligands |
| WO2006081230A2 (en) | 2005-01-26 | 2006-08-03 | Schering Corporation | 3-(indazol-5-yl)-(1,2, 4) triazine derivatives and related compounds as protein kinase inhibitors for the treatment of cancer |
| KR20080027775A (ko) * | 2005-05-17 | 2008-03-28 | 플렉시콘, 인코퍼레이티드 | 피롤(２,３-ｂ)피리딘 유도체 단백질 키나제 억제제 |
| CA2612723A1 (en) | 2005-06-24 | 2007-01-04 | Eli Lilly And Company | Tetrahydrocarbazole derivatives useful as androgen receptor modulators |
| US7655662B2 (en) | 2005-12-22 | 2010-02-02 | Alcon Research, Ltd. | (Indazol-5-yl)-pyrazines and (1,3-dihydro-indol-2-one)-pyrazines for treating glaucoma and controlling intraocular pressure |
| WO2008085302A1 (en) * | 2006-12-20 | 2008-07-17 | Merck & Co., Inc. | Imidazopyridine analogs as cb2 receptor modulators, useful in the treatment of pain, respiratory and non-respiratory diseases |
| BRPI0809998B8 (pt) | 2007-04-03 | 2021-05-25 | Array Biopharma Inc | composto de imidazo[1,2-a] piridina como inibidores do receptor tirosina quinase, seus usos, seus processos de preparação e composições farmacêuticas |
| WO2009071483A1 (en) | 2007-12-07 | 2009-06-11 | Via Pharmaceuticals, Inc. | 1- (indaz0l-5-yl) -ureas as diacylglycerol acyltransferase inhibitors |
| FR2926556B1 (fr) * | 2008-01-22 | 2010-02-19 | Sanofi Aventis | Derives de carboxamides n-azabicycliques, leur preparation et leur application en therapeutique |
| WO2009147189A1 (en) * | 2008-06-05 | 2009-12-10 | Glaxo Group Limited | Novel compounds |
| RU2562977C2 (ru) * | 2009-12-21 | 2015-09-10 | Эррэй Биофарма Инк. | СОЕДИНЕНИЯ ЗАМЕЩЕННОГО N-(1Н-ИНДАЗОЛ-4-ИЛ)ИМИДАЗОЛ[1,2-a]ПИРИДИН-3-КАРБОКСАМИДА КАК ИНГИБИТОРЫ cFMS |
| CA3027814A1 (en) * | 2010-12-13 | 2012-06-21 | Array Biopharma Inc. | Substituted n-(1h-indazol-4-yl)imidazo[1,2-a]pyridine-3-carboxamide compounds as intermediates for type iii receptor tyrosine kinase inhibitors |
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2010
- 2010-12-20 RU RU2012131129/04A patent/RU2562977C2/ru active
- 2010-12-20 WO PCT/US2010/061341 patent/WO2011079076A1/en active Application Filing
- 2010-12-20 BR BR112012017123-2A patent/BR112012017123B1/pt active IP Right Grant
- 2010-12-20 MY MYPI2012002855A patent/MY163791A/en unknown
- 2010-12-20 UA UAA201208998A patent/UA108222C2/ru unknown
- 2010-12-20 SI SI201030706T patent/SI2516433T1/sl unknown
- 2010-12-20 ES ES10798683.8T patent/ES2494590T3/es active Active
- 2010-12-20 JP JP2012546120A patent/JP5739448B2/ja active Active
- 2010-12-20 CN CN201080064462.XA patent/CN102822170B/zh active Active
- 2010-12-20 CA CA2785338A patent/CA2785338C/en active Active
- 2010-12-20 SG SG2012046009A patent/SG181861A1/en unknown
- 2010-12-20 AR ARP100104761A patent/AR079541A1/es active IP Right Grant
- 2010-12-20 EP EP10798683.8A patent/EP2516433B1/en active Active
- 2010-12-20 DK DK10798683.8T patent/DK2516433T3/da active
- 2010-12-20 KR KR1020127019199A patent/KR101779630B1/ko active IP Right Grant
- 2010-12-20 AU AU2010333752A patent/AU2010333752B2/en active Active
- 2010-12-20 NZ NZ601376A patent/NZ601376A/en not_active IP Right Cessation
- 2010-12-20 MX MX2012007329A patent/MX2012007329A/es active IP Right Grant
- 2010-12-20 ME MEP-2014-99A patent/ME01894B/me unknown
- 2010-12-20 PT PT107986838T patent/PT2516433E/pt unknown
- 2010-12-20 RS RSP20140440 patent/RS53500B1/en unknown
- 2010-12-20 US US13/517,938 patent/US8841455B2/en active Active
- 2010-12-20 PL PL10798683T patent/PL2516433T3/pl unknown
- 2010-12-21 TW TW99145074A patent/TWI471326B/zh active
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2012
- 2012-06-21 IL IL220544A patent/IL220544A/en active IP Right Grant
- 2012-06-21 CL CL2012001699A patent/CL2012001699A1/es unknown
- 2012-07-19 CO CO12122160A patent/CO6561821A2/es unknown
- 2012-07-20 CR CR20120389A patent/CR20120389A/es unknown
- 2012-07-20 ZA ZA2012/05505A patent/ZA201205505B/en unknown
-
2013
- 2013-03-25 HK HK13103717.1A patent/HK1176928A1/xx unknown
-
2014
- 2014-08-18 HR HRP20140770AT patent/HRP20140770T1/hr unknown
- 2014-09-30 SM SM201400142T patent/SMT201400142B/xx unknown
-
2015
- 2015-01-22 JP JP2015010346A patent/JP2015107999A/ja not_active Withdrawn
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