DK2430191T3 - PHOSPHODIESTERASE-4D7 AS A MARKET FOR PROSTATACANCES - Google Patents

PHOSPHODIESTERASE-4D7 AS A MARKET FOR PROSTATACANCES Download PDF

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Publication number
DK2430191T3
DK2430191T3 DK10726251.1T DK10726251T DK2430191T3 DK 2430191 T3 DK2430191 T3 DK 2430191T3 DK 10726251 T DK10726251 T DK 10726251T DK 2430191 T3 DK2430191 T3 DK 2430191T3
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Prior art keywords
pde4d7
expression
prostate cancer
sample
hormone
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DK10726251.1T
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Danish (da)
English (en)
Inventor
Ralf Hoffmann
Miles D Houslay
David J P Henderson
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Koninklijke Philips Nv
Univ Court Univ Of Glasgow
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
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    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • C12Y301/04—Phosphoric diester hydrolases (3.1.4)
    • C12Y301/04017—3',5'-Cyclic-nucleotide phosphodiesterase (3.1.4.17)
    • G01N33/57555—
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • C12N2310/10—Type of nucleic acid
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2310/141—MicroRNAs, miRNAs
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    • C12Q2600/00—Oligonucleotides characterized by their use
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
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    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/916—Hydrolases (3) acting on ester bonds (3.1), e.g. phosphatases (3.1.3), phospholipases C or phospholipases D (3.1.4)
    • G—PHYSICS
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    • G01N2800/00—Detection or diagnosis of diseases
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    • G—PHYSICS
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/54—Determining the risk of relapse
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    • Y10S436/00—Chemistry: analytical and immunological testing
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    • Y10S436/813—Cancer

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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK10726251.1T 2009-05-12 2010-05-11 PHOSPHODIESTERASE-4D7 AS A MARKET FOR PROSTATACANCES DK2430191T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09159960 2009-05-12
PCT/IB2010/052073 WO2010131195A1 (en) 2009-05-12 2010-05-11 Phosphodiesterase 4d7 as prostate cancer marker

Publications (1)

Publication Number Publication Date
DK2430191T3 true DK2430191T3 (en) 2018-12-10

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DK10726251.1T DK2430191T3 (en) 2009-05-12 2010-05-11 PHOSPHODIESTERASE-4D7 AS A MARKET FOR PROSTATACANCES

Country Status (10)

Country Link
US (1) US8753892B2 (enExample)
EP (2) EP3434787B1 (enExample)
JP (4) JP6148007B2 (enExample)
KR (1) KR101778036B1 (enExample)
CN (2) CN102549167B (enExample)
BR (1) BRPI1007093A2 (enExample)
DK (1) DK2430191T3 (enExample)
ES (1) ES2700877T3 (enExample)
RU (1) RU2651474C2 (enExample)
WO (1) WO2010131195A1 (enExample)

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KR20220008175A (ko) * 2020-07-13 2022-01-20 가톨릭대학교 산학협력단 전립선암 환자의 예후 진단 및 치료 전략 결정용 병리등급 특이적 마커
CN112779348B (zh) * 2020-12-31 2022-05-20 四川农业大学 一种小麦单位面积穗数主效qtl位点及紧密连锁的kasp引物和应用
EP4360711A1 (en) * 2022-10-27 2024-05-01 Koninklijke Philips N.V. Treatment of prostate cancer by promoting pde4d7
WO2024088865A1 (en) 2022-10-27 2024-05-02 Koninklijke Philips N.V. Treatment of prostate cancer by promoting pde4d7
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CN102549167A (zh) 2012-07-04
EP2430191A1 (en) 2012-03-21
JP2016034277A (ja) 2016-03-17
EP3434787A1 (en) 2019-01-30
US8753892B2 (en) 2014-06-17
EP2430191B1 (en) 2018-09-19
ES2700877T3 (es) 2019-02-19
US20120065148A1 (en) 2012-03-15
JP6148007B2 (ja) 2017-06-14
CN107267482A (zh) 2017-10-20
RU2011150279A (ru) 2013-06-20
JP2017184729A (ja) 2017-10-12
RU2651474C2 (ru) 2018-04-19
KR20120034651A (ko) 2012-04-12
KR101778036B1 (ko) 2017-09-14
EP3434787B1 (en) 2024-10-09
BRPI1007093A2 (pt) 2017-06-06
JP2012526545A (ja) 2012-11-01
CN102549167B (zh) 2017-04-26
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JP6430560B2 (ja) 2018-11-28
WO2010131195A1 (en) 2010-11-18
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