DK2384192T3 - Biologisk oliesammensætning, formuleringer, der omfatter oliesammensætningen, og anvendelse deraf til at forebygge eller behandle kardiovaskulær sygdom - Google Patents

Biologisk oliesammensætning, formuleringer, der omfatter oliesammensætningen, og anvendelse deraf til at forebygge eller behandle kardiovaskulær sygdom Download PDF

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Publication number
DK2384192T3
DK2384192T3 DK10700011.9T DK10700011T DK2384192T3 DK 2384192 T3 DK2384192 T3 DK 2384192T3 DK 10700011 T DK10700011 T DK 10700011T DK 2384192 T3 DK2384192 T3 DK 2384192T3
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Denmark
Prior art keywords
oil composition
composition
epa
dha
oil
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DK10700011.9T
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English (en)
Inventor
Jan Raa
Gunnar Rørstad
Kurt Steinar Tande
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Calanus As
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Publication of DK2384192T3 publication Critical patent/DK2384192T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23DEDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
    • A23D9/00Other edible oils or fats, e.g. shortenings, cooking oils
    • A23D9/007Other edible oils or fats, e.g. shortenings, cooking oils characterised by ingredients other than fatty acid triglycerides
    • A23D9/013Other fatty acid esters, e.g. phosphatides
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115Fatty acids or derivatives thereof; Fats or oils
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/201Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/232Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicinal Preparation (AREA)

Claims (13)

1. Biologisk oliesammensætning, der omfatter 20-100 vægt-% voksestere, fortrinsvis 70-100 vægt-% voksestere, og hvor sammensætningen omfatter 5-20 vægt-% stearidonsyre (SDA), til anvendelse som et medikament til forebyggelse eller behandling af en kardiovaskulær sygdom.
2. Biologisk oliesammensætning ifølge krav 1 til anvendelse som et medikament til forebyggelse eller behandling af aterosklerose.
3. Biologisk sammensætning ifølge krav 1 til anvendelse som et medikament til forebyggelse eller behandling af hyperkolesterolæmi.
4. Biologisk sammensætning ifølge krav 1 til anvendelse som medikament til forebyggelse eller behandling af forhøjede kolesterolniveauer i blodet.
5. Biologisk oliesammensætning til anvendelse ifølge et hvilket som helst af kravene 1 til 4, hvor sammensætningen omfatter 3-15 vægt-% eicosapentaensyre (EPA) og 2-10 vægt-% docosahexaensyre (DHA).
6. Biologisk oliesammensætning til anvendelse ifølge et hvilket som helst af kravene 1 til 5, hvor sammensætningen omfatter fedtalkoholer og SDA, DHA og EPA som monoestere med fedtalkoholer.
7. Biologisk oliesammensætning til anvendelse ifølge et hvilket som helst af kravene 1 til 6, hvor sammensætningen indeholder 1000-4000 ppm astaxanthin.
8. Biologisk oliesammensætning til anvendelse ifølge et hvilket som helst af kravene 1 til 7, hvor sammensætningen er isoleret fra en copepod.
9. Biologisk oliesammensætning til anvendelse ifølge krav 8, hvor copepoden er af arten Calanus.
10. Biologisk oliesammensætning til anvendelse ifølge krav 9, hvor copepoden er af arten Calanus finmarchicus.
11. Farmaceutisk formulering, der omfatter en biologisk oliesammensætning ifølge et hvilket som helst af kravene 1-10 til anvendelse i terapi.
12. Formulering til anvendelse ifølge krav 11, der er tilvejebragt i kapsler, tabletter, emulsioner eller tonika.
13. Formulering til anvendelse ifølge krav 12, der omfatter ét eller flere farmaceutisk acceptable additiver udvalgt fra gruppen bestående af adjuvans, antioxidanter, emulgeringsmidler, overfladeaktive midler og bærere.
DK10700011.9T 2009-01-05 2010-01-04 Biologisk oliesammensætning, formuleringer, der omfatter oliesammensætningen, og anvendelse deraf til at forebygge eller behandle kardiovaskulær sygdom DK2384192T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NO20090033 2009-01-05
PCT/NO2010/000002 WO2010077152A1 (en) 2009-01-05 2010-01-04 Biological oil composition, formulations comprising the oil composition, and use thereof to prevent or treat cardiovascular disease

Publications (1)

Publication Number Publication Date
DK2384192T3 true DK2384192T3 (da) 2018-01-08

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DK10700011.9T DK2384192T3 (da) 2009-01-05 2010-01-04 Biologisk oliesammensætning, formuleringer, der omfatter oliesammensætningen, og anvendelse deraf til at forebygge eller behandle kardiovaskulær sygdom

Country Status (10)

Country Link
US (2) US20110251276A1 (da)
EP (1) EP2384192B1 (da)
JP (2) JP2012514596A (da)
CN (1) CN102271670A (da)
CA (1) CA2750153C (da)
DK (1) DK2384192T3 (da)
ES (1) ES2653940T3 (da)
NO (1) NO2384192T3 (da)
RU (1) RU2563995C2 (da)
WO (1) WO2010077152A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010143977A1 (en) * 2009-06-12 2010-12-16 Calanus As Copepod oil composition, formulations comprising the oil composition, and the use thereof to reduce accumulation of visceral fat, improve glucose tolerance, and prevent or treat obesity related diseases and disorders
CN106999460B (zh) * 2014-08-12 2021-07-09 信息化学和应用神经研究所 用于抑制海虱附着于鱼上的棕榈油酸
IT201700054543A1 (it) 2017-05-19 2018-11-19 Gleaner Srls Preparato come fonte di Omega-3
CN107802643B (zh) * 2017-12-12 2020-03-27 江苏扬新生物医药有限公司 一种含有虾青素的软胶囊
JP2020061956A (ja) * 2018-10-16 2020-04-23 日本水産株式会社 血清中tmao低減用組成物

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8819110D0 (en) 1988-08-11 1988-09-14 Norsk Hydro As Antihypertensive drug & method for production
IT1277953B1 (it) * 1995-12-21 1997-11-12 Sigma Tau Ind Farmaceuti Composizione farmaceutica contenente l-carnitina o una alcanoil l- carnitina e un acido poliinsaturo della serie 3-omega utile per
JPH10155459A (ja) * 1996-11-27 1998-06-16 Suntory Ltd アスタキサンチン含有飲食物
IT1292126B1 (it) * 1997-06-11 1999-01-25 Guido Galliani Esteri cerosi arricchiti in acidi grassi omega-3 insaturi,loro preparazione ed uso
US6175001B1 (en) 1998-10-16 2001-01-16 The Scripps Research Institute Functionalized pyrimidine nucleosides and nucleotides and DNA's incorporating same
CA2251265A1 (en) 1998-10-21 2000-04-21 Universite De Sherbrooke Process for lipid extraction of aquatic animal tissues producing a dehydrated residue
GB0016452D0 (en) 2000-07-04 2000-08-23 Kilgowan Limited Vitamin K and essential fatty acids
WO2002092779A2 (en) * 2001-05-17 2002-11-21 Pilot Therapeutics, Inc. Method for enriching tissues in long chain polyunsaturated fatty acids
US6500468B1 (en) * 2002-01-03 2002-12-31 Farlong Pharmaceutical, Inc. Panax notoginsenoside composition
US20060127449A1 (en) * 2003-01-28 2006-06-15 Hargrove James L Method and composition for lowering cholesterol
US8075910B2 (en) * 2004-05-20 2011-12-13 Pbm Pharmaceuticals, Inc. Oral compositions comprising edible oils and vitamins and/or minerals and methods for making oral compositions
AU2005322015B2 (en) * 2004-12-29 2010-02-25 Hill's Pet Nutrition, Inc. Methods for inhibiting a decline in learning and/or memory in animals
CN101437508A (zh) * 2006-03-03 2009-05-20 孟山都技术有限公司 用于改善心血管健康的十八碳四烯酸
MX2009004337A (es) 2006-11-01 2009-05-22 Pronova Biopharma Norge As Compuestos lipidos omega-3.
EP2144618B1 (en) * 2007-03-28 2013-05-15 Aker Biomarine ASA Bioeffective krill oil compositions

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Publication number Publication date
WO2010077152A1 (en) 2010-07-08
CA2750153A1 (en) 2010-07-08
CN102271670A (zh) 2011-12-07
EP2384192A1 (en) 2011-11-09
US9820958B2 (en) 2017-11-21
JP2015180640A (ja) 2015-10-15
CA2750153C (en) 2016-11-08
RU2563995C2 (ru) 2015-09-27
ES2653940T3 (es) 2018-02-09
JP2012514596A (ja) 2012-06-28
US20140302128A1 (en) 2014-10-09
EP2384192B1 (en) 2017-10-25
JP5932111B2 (ja) 2016-06-08
RU2011130700A (ru) 2013-02-10
US20110251276A1 (en) 2011-10-13
NO2384192T3 (da) 2018-03-24

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