DK2338052T3 - Fremgangsmåde og anordning til bestemmelse af mængden af magnetisk-mærkede målkomponenter - Google Patents

Fremgangsmåde og anordning til bestemmelse af mængden af magnetisk-mærkede målkomponenter Download PDF

Info

Publication number
DK2338052T3
DK2338052T3 DK09808959.2T DK09808959T DK2338052T3 DK 2338052 T3 DK2338052 T3 DK 2338052T3 DK 09808959 T DK09808959 T DK 09808959T DK 2338052 T3 DK2338052 T3 DK 2338052T3
Authority
DK
Denmark
Prior art keywords
determining
labeled target
target components
magnetically labeled
magnetically
Prior art date
Application number
DK09808959.2T
Other languages
English (en)
Inventor
Toon H Evers
Wendy U Dittmer
Original Assignee
Koninklijke Philips Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninklijke Philips Nv filed Critical Koninklijke Philips Nv
Application granted granted Critical
Publication of DK2338052T3 publication Critical patent/DK2338052T3/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y25/00—Nanomagnetism, e.g. magnetoimpedance, anisotropic magnetoresistance, giant magnetoresistance or tunneling magnetoresistance
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/72—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables
    • G01N27/74—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
    • G01N27/745—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids for detecting magnetic beads used in biochemical assays
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/02—Measuring direction or magnitude of magnetic fields or magnetic flux
    • G01R33/06—Measuring direction or magnitude of magnetic fields or magnetic flux using galvano-magnetic devices
    • G01R33/09—Magnetoresistive devices
    • G01R33/093—Magnetoresistive devices using multilayer structures, e.g. giant magnetoresistance sensors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/12—Measuring magnetic properties of articles or specimens of solids or fluids
    • G01R33/1269—Measuring magnetic properties of articles or specimens of solids or fluids of molecules labeled with magnetic beads
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
DK09808959.2T 2008-10-16 2009-10-06 Fremgangsmåde og anordning til bestemmelse af mængden af magnetisk-mærkede målkomponenter DK2338052T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08166810 2008-10-16
PCT/IB2009/054372 WO2010044005A2 (en) 2008-10-16 2009-10-06 Method and device for determining the amount of magnetically labeled target components

Publications (1)

Publication Number Publication Date
DK2338052T3 true DK2338052T3 (da) 2020-02-17

Family

ID=42028175

Family Applications (1)

Application Number Title Priority Date Filing Date
DK09808959.2T DK2338052T3 (da) 2008-10-16 2009-10-06 Fremgangsmåde og anordning til bestemmelse af mængden af magnetisk-mærkede målkomponenter

Country Status (9)

Country Link
US (1) US9023651B2 (da)
EP (1) EP2338052B1 (da)
JP (1) JP5567577B2 (da)
CN (1) CN102187222B (da)
BR (1) BRPI0914018A2 (da)
DK (1) DK2338052T3 (da)
ES (1) ES2773075T3 (da)
RU (1) RU2530715C2 (da)
WO (1) WO2010044005A2 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011112929A2 (en) * 2010-03-12 2011-09-15 The Board Of Trustees Of The Leland Stanford Junior University Magnetic sensor based quantitative binding kinetics analysis
US9778225B2 (en) 2010-11-15 2017-10-03 Regents Of The University Of Minnesota Magnetic search coil for measuring real-time brownian relaxation of magnetic nanoparticles
BR112013013109B1 (pt) * 2010-11-30 2021-02-09 Koninklijke Philips N.V. dispositivo sensor para a detecção de partículas magnéticas em uma câmara de amostras com uma superfície de contato em que as partículas magnéticas podem ser coletadas
CN103917638A (zh) * 2011-09-08 2014-07-09 Nexusdx股份有限公司 多级分析物检定
ES2608930T3 (es) 2012-01-04 2017-04-17 Magnomics, S.A. Dispositivo monolítico que combina CMOS con sensores magnetorresistivos
CA2804843C (en) * 2012-02-06 2021-02-02 Ortho-Clinical Diagnostics, Inc. Multiple time windows for extending the range of an assay
EP2685273A1 (en) * 2012-07-13 2014-01-15 Université Montpellier 2, Sciences et Techniques Micromagnetometry detection system and method for detecting magnetic signatures of magnetic materials
EP2893335A1 (en) 2012-09-04 2015-07-15 Koninklijke Philips N.V. A sensor device and a method of sampling
CN110366558A (zh) 2016-10-28 2019-10-22 班扬生物标记公司 针对泛素c末端水解酶l1(uch-l1)和胶质纤维酸性蛋白(gfap)的抗体及相关方法
JP7455529B2 (ja) 2019-08-01 2024-03-26 キヤノンメディカルシステムズ株式会社 検体測定装置及び検体測定装置の制御方法
WO2022139819A1 (en) * 2020-12-22 2022-06-30 Hp Health Solutions Inc. Washing magnetizing microparticles in a fluid density column

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4368047A (en) 1981-04-27 1983-01-11 University Of Utah Research Foundation Process for conducting fluorescence immunoassays without added labels and employing attenuated internal reflection
US5846708A (en) 1991-11-19 1998-12-08 Massachusetts Institiute Of Technology Optical and electrical methods and apparatus for molecule detection
JPH0763760A (ja) 1993-08-31 1995-03-10 Daikin Ind Ltd 光学的免疫測定方法およびその装置
GB9609653D0 (en) 1996-05-09 1996-07-10 Applied Research Ars Holding N Method of assay
US5885839A (en) 1997-04-15 1999-03-23 Lxn Corporation Methods of determining initiation and variable end points for measuring a chemical reaction
US6551843B1 (en) * 1999-01-29 2003-04-22 Immunivest Corporation Methods for enhancing binding interactions between members of specific binding pairs
RU2166751C1 (ru) * 2000-03-09 2001-05-10 Никитин Петр Иванович Способ анализа смеси биологических и/или химических компонентов с использованием магнитных частиц и устройство для его осуществления
WO2002029411A2 (en) 2000-10-03 2002-04-11 Minerva Biotechnologies Corporation Magnetic in situ dilution
DE10051396A1 (de) * 2000-10-17 2002-04-18 Febit Ferrarius Biotech Gmbh Verfahren und Vorrichtung zur integrierten Synthese und Analytbestimmung an einem Träger
US6541266B2 (en) 2001-02-28 2003-04-01 Home Diagnostics, Inc. Method for determining concentration of an analyte in a test strip
US20030170686A1 (en) * 2001-12-07 2003-09-11 Rene Hoet Method and apparatus for washing magnetically responsive particles
US7048890B2 (en) * 2001-12-21 2006-05-23 Koninklijke Philips Electronics N.V. Sensor and method for measuring the areal density of magnetic nanoparticles on a micro-array
DE60315415T2 (de) * 2002-01-29 2008-04-30 Asahi Kasei Kabushiki Kaisha Biosensor, magnetisches molekül messverfahren und messobjekt messverfahren
US20040033627A1 (en) * 2002-05-31 2004-02-19 The Regents Of The University Of California Method and apparatus for detecting substances of interest
US7118916B2 (en) 2002-10-21 2006-10-10 Lifescan, Inc. Method of reducing analysis time of endpoint-type reaction profiles
US20060194327A1 (en) 2003-07-30 2006-08-31 Koninklijke Philips Electronics N.V. On-chip magnetic particle sensor with improved snr
US20080309329A1 (en) 2003-07-30 2008-12-18 Koninklike Philips Electronics N.V. On-Chip Magnetic Sensor Device with Suppressed Cross-Talk
GB0410976D0 (en) 2004-05-17 2004-06-16 Randox Lab Ltd Magnetic particle detector system
US20090206825A1 (en) * 2004-11-30 2009-08-20 Koninklijke Philips Electronics, N.V. Excitation and measurement method for a magnetic biosensor
US7723127B2 (en) 2005-03-03 2010-05-25 Novx Systems Inc. Immunoassay with extended dynamic range
RU2008101774A (ru) * 2005-06-17 2009-07-27 Конинклейке Филипс Электроникс Н.В. (Nl) Быстродействующий магнитный биодатчик с интегрированным измерением времени поступления
US8945946B2 (en) * 2006-03-31 2015-02-03 Canon Kabushiki Kaisha Sensor element and detection method of magnetic particles using this element, and detection method of target substance
WO2007132367A1 (en) * 2006-05-09 2007-11-22 Koninklijke Philips Electronics N.V. Accurate magnetic biosensor
EP2115468B1 (en) 2007-02-23 2010-06-16 Koninklijke Philips Electronics N.V. A sensor device for and a method of sensing magnetic particles
EP2175997A1 (en) 2007-07-09 2010-04-21 Philips Intellectual Property & Standards GmbH Microelectronic sensor device with magnetic field generator and carrier

Also Published As

Publication number Publication date
WO2010044005A2 (en) 2010-04-22
ES2773075T3 (es) 2020-07-09
US9023651B2 (en) 2015-05-05
EP2338052A2 (en) 2011-06-29
JP5567577B2 (ja) 2014-08-06
BRPI0914018A2 (pt) 2015-10-27
US20110207229A1 (en) 2011-08-25
RU2011119508A (ru) 2012-11-27
CN102187222B (zh) 2014-05-07
CN102187222A (zh) 2011-09-14
RU2530715C2 (ru) 2014-10-10
WO2010044005A3 (en) 2010-07-08
EP2338052B1 (en) 2019-11-20
JP2012506043A (ja) 2012-03-08

Similar Documents

Publication Publication Date Title
DK2338052T3 (da) Fremgangsmåde og anordning til bestemmelse af mængden af magnetisk-mærkede målkomponenter
DK3375470T3 (da) Apparat og fremgangsmåde til pumpning af fluid
DK2300137T3 (da) Fremgangsmåde og indretning til aflæsning af en emulsion
DK2081669T3 (da) Fremgangsmåde og anordning til fremstilling af granulater
DK2158726T3 (da) Fremgangsmåde og system til bestemmelse af fysisk placering af udstyr
DK2062067T3 (da) Fremgangsmåde og anordning til sporing af en genstand
DK2239583T3 (da) Tyndfilmslagdelt centrifugeindretning og analysefremgangsmåde til anvendelse deraf
DK2342858T3 (da) Fremgangsmåde og apparat til tilvejebringelse af redundansversioner
DK2471441T3 (da) Fremgangsmåde og anordning til bestemmelse af øjets rotationscenterpunkt
DK2195608T3 (da) System og fremgangsmåde til flerbilledoverflademåling af genstandes form
DK2266710T3 (da) Apparat til orientering af magnetspåner
DK3730045T3 (da) Fremgangsmåde til indføring af en analytsensor
FI20080182A0 (fi) Mittausmenetelmä ja -laite
DK2242597T3 (da) Apparat og fremgangsmåde til fremstilling af metalbeholdere
DK2718543T3 (da) Fremgangsmåde og apparat til bestemmelse af borehulsparametre
DK2277382T3 (da) Fremgangsmåde og indretning til læsning af kød med ben
DK2285715T3 (da) Indretning til behandling af varestrømme og fremgangsmåde til denne
DK2228629T3 (da) System og fremgangsmåde til bestemmelse af positionen af en motordel
DK2545368T3 (da) Fremgangsmåde og indretning til magnetisk forudsigelse af revnedybde
DK2346765T3 (da) Indretning og fremgangsmåde til samling af flade genstande
DK2210081T3 (da) Fremgangsmåde til identificering og håndtering af partikler
DK2403994T3 (da) Apparat og metode til håndtering af jernbanesveller
BRPI0912722A2 (pt) método de ensaio magnético e aparelhagem de ensaio magnético
DK2335042T3 (da) Fluidum-analyseanlæg og fremgangsmåde til drift af dette analyseanlæg
DK2252890T3 (da) Fremgangsmåde og anordning til påvisning af kulhydrater