DK2321290T3 - Asymmetrisk fremgangsmåde til fremstilling af substituerede 2-amino-thiazoloner - Google Patents

Asymmetrisk fremgangsmåde til fremstilling af substituerede 2-amino-thiazoloner

Info

Publication number
DK2321290T3
DK2321290T3 DK09790875.0T DK09790875T DK2321290T3 DK 2321290 T3 DK2321290 T3 DK 2321290T3 DK 09790875 T DK09790875 T DK 09790875T DK 2321290 T3 DK2321290 T3 DK 2321290T3
Authority
DK
Denmark
Prior art keywords
thiazolones
amino
preparing substituted
asymmetric
procedure
Prior art date
Application number
DK09790875.0T
Other languages
English (en)
Inventor
Seb Caille
Xiang Wang
Sheng Cui
Margaret Faul
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Application granted granted Critical
Publication of DK2321290T3 publication Critical patent/DK2321290T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/54Nitrogen and either oxygen or sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/4261,3-Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK09790875.0T 2008-07-29 2009-07-28 Asymmetrisk fremgangsmåde til fremstilling af substituerede 2-amino-thiazoloner DK2321290T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8454908P 2008-07-29 2008-07-29
PCT/US2009/051929 WO2010014586A1 (en) 2008-07-29 2009-07-28 Asymmetric process for making substituted 2-amino-thiazolones

Publications (1)

Publication Number Publication Date
DK2321290T3 true DK2321290T3 (da) 2012-07-16

Family

ID=41020998

Family Applications (1)

Application Number Title Priority Date Filing Date
DK09790875.0T DK2321290T3 (da) 2008-07-29 2009-07-28 Asymmetrisk fremgangsmåde til fremstilling af substituerede 2-amino-thiazoloner

Country Status (21)

Country Link
US (2) US8501954B2 (da)
EP (1) EP2321290B1 (da)
JP (1) JP2011529896A (da)
KR (1) KR20110048520A (da)
CN (1) CN102112454B (da)
AU (1) AU2009276757A1 (da)
BR (1) BRPI0916270A2 (da)
CA (1) CA2730711A1 (da)
CL (1) CL2011000120A1 (da)
CY (1) CY1113135T1 (da)
DK (1) DK2321290T3 (da)
EA (1) EA019573B1 (da)
ES (1) ES2386613T3 (da)
HK (1) HK1154000A1 (da)
IL (1) IL210562A (da)
MX (1) MX2011001009A (da)
PL (1) PL2321290T3 (da)
PT (1) PT2321290E (da)
SI (1) SI2321290T1 (da)
WO (1) WO2010014586A1 (da)
ZA (1) ZA201100358B (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5651110B2 (ja) 2008-07-29 2015-01-07 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規化合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005116002A2 (en) * 2004-05-24 2005-12-08 Amgen Inc. Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1
US8541592B2 (en) * 2005-11-22 2013-09-24 Amgen Inc. Inhibitors of 11-beta-hydroxysteroid dehydrogenase type 1
EP1951695B1 (en) 2005-11-22 2009-12-23 Amgen Inc. CATALYZED PROCESS OF MAKING C-5-SUBSTITUTED HETEROCYCLIC INHIBITORS OF 11ß-HYDROXY STEROID DEHYDROGENASE TYPE 1
MX2009013869A (es) 2007-06-21 2010-03-17 Amgen Inc Proceso para hacer 2-amino-tiazolonas sustituidas.

Also Published As

Publication number Publication date
EA019573B1 (ru) 2014-04-30
AU2009276757A1 (en) 2010-02-04
ZA201100358B (en) 2011-10-26
IL210562A0 (en) 2011-03-31
CN102112454B (zh) 2013-09-04
JP2011529896A (ja) 2011-12-15
MX2011001009A (es) 2011-04-27
US20110178307A1 (en) 2011-07-21
US8501954B2 (en) 2013-08-06
SI2321290T1 (sl) 2012-09-28
KR20110048520A (ko) 2011-05-11
CL2011000120A1 (es) 2011-06-24
CY1113135T1 (el) 2016-04-13
WO2010014586A1 (en) 2010-02-04
IL210562A (en) 2013-11-28
CA2730711A1 (en) 2010-02-04
ES2386613T3 (es) 2012-08-23
EP2321290A1 (en) 2011-05-18
US20130345432A1 (en) 2013-12-26
EA201170072A1 (ru) 2011-08-30
EP2321290B1 (en) 2012-06-20
PL2321290T3 (pl) 2012-11-30
CN102112454A (zh) 2011-06-29
HK1154000A1 (en) 2012-04-13
BRPI0916270A2 (pt) 2018-10-16
PT2321290E (pt) 2012-08-10

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