DK230489A - Rekombinant-dna-vektorer, der koder for en 4ae-0-isovalerylacylase afledt af et carbomycin-biosyntesegen, betegnet care, til anvendelse i streptomyces og andre organismer - Google Patents

Rekombinant-dna-vektorer, der koder for en 4ae-0-isovalerylacylase afledt af et carbomycin-biosyntesegen, betegnet care, til anvendelse i streptomyces og andre organismer Download PDF

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Publication number
DK230489A
DK230489A DK230489A DK230489A DK230489A DK 230489 A DK230489 A DK 230489A DK 230489 A DK230489 A DK 230489A DK 230489 A DK230489 A DK 230489A DK 230489 A DK230489 A DK 230489A
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DK
Denmark
Prior art keywords
streptomycies
isovalerylacylase
biosynth
carbomycin
organisms
Prior art date
Application number
DK230489A
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Danish (da)
English (en)
Other versions
DK230489D0 (da
Inventor
Janet Kay Epp
Brigitte Elisabeth Schoner
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK230489D0 publication Critical patent/DK230489D0/da
Publication of DK230489A publication Critical patent/DK230489A/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
DK230489A 1988-05-13 1989-05-11 Rekombinant-dna-vektorer, der koder for en 4ae-0-isovalerylacylase afledt af et carbomycin-biosyntesegen, betegnet care, til anvendelse i streptomyces og andre organismer DK230489A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/194,672 US5068189A (en) 1988-05-13 1988-05-13 Recombinant dna vectors encoding a 4"-o-isovaleryl acylase derived from a carbomycin biosynthetic gene, designated care, for use in streptomyces and other organisms

Publications (2)

Publication Number Publication Date
DK230489D0 DK230489D0 (da) 1989-05-11
DK230489A true DK230489A (da) 1990-01-24

Family

ID=22718473

Family Applications (1)

Application Number Title Priority Date Filing Date
DK230489A DK230489A (da) 1988-05-13 1989-05-11 Rekombinant-dna-vektorer, der koder for en 4ae-0-isovalerylacylase afledt af et carbomycin-biosyntesegen, betegnet care, til anvendelse i streptomyces og andre organismer

Country Status (7)

Country Link
US (1) US5068189A (de)
EP (1) EP0354641B1 (de)
JP (1) JPH0213380A (de)
CA (1) CA1336693C (de)
DE (1) DE68918532T2 (de)
DK (1) DK230489A (de)
IL (1) IL90268A (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2749616B2 (ja) * 1988-05-24 1998-05-13 メルシャン株式会社 マクロライド抗生物質の４”位アシル化酵素をコードする遺伝子
KR0153059B1 (ko) 1995-06-12 1998-11-16 김광호 색상조절상태를 온 스크린 디스플레이하는 컬러영상기기
WO1997022711A1 (en) 1995-12-19 1997-06-26 Regents Of The University Of Minnesota Metabolic engineering of polyhydroxyalkanoate monomer synthases
US6265202B1 (en) 1998-06-26 2001-07-24 Regents Of The University Of Minnesota DNA encoding methymycin and pikromycin
US20030194784A1 (en) * 2001-04-17 2003-10-16 Sherman David H. DNA encoding methymycin and pikromycin
US7579167B2 (en) 2002-10-08 2009-08-25 Aventis Pharma S. Polypeptides involved in the biosynthesis of spiramycins, nucleotide sequences encoding these polypeptides and applications thereof
EP1905833B1 (de) * 2002-10-08 2015-08-12 Aventis Pharma S.A. Polypeptide, die an der Biosynthese von Spiramycinen beteiligt sind, Nukleotidsequenzen, die diese Polypetide kodieren, und ihre Anwendungen
BRPI0314543B8 (pt) * 2002-10-08 2021-05-25 Aventis Pharma Sa células hospedeiras, dna recombinante, utilização dos mesmos, processos de produção de um polipeptídeo implicado na biossíntese das espiramicinas, de produção de macrolídeos e de produção de espiramicina(s), e micro-organismo transgênico mutante produtor de macrolídeo
CN105505954B (zh) * 2015-12-31 2019-01-22 沈阳福洋医药科技有限公司 可利霉素生物合成基因簇

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4935340A (en) * 1985-06-07 1990-06-19 Eli Lilly And Company Method of isolating antibiotic biosynthetic genes
IL83601A0 (en) * 1986-08-28 1988-01-31 Lilly Co Eli Method for selecting recombinant dna-containing streptomyces and other host cells
US4952502A (en) * 1987-02-24 1990-08-28 Eli Lilly And Company Carbomycin biosynthetic gene, designated carG, for use in streptomyces and other organisms

Also Published As

Publication number Publication date
EP0354641A3 (en) 1990-05-23
DE68918532D1 (de) 1994-11-03
EP0354641B1 (de) 1994-09-28
IL90268A (en) 1994-10-07
DK230489D0 (da) 1989-05-11
IL90268A0 (en) 1989-12-15
CA1336693C (en) 1995-08-15
DE68918532T2 (de) 1995-03-02
JPH0213380A (ja) 1990-01-17
EP0354641A2 (de) 1990-02-14
US5068189A (en) 1991-11-26

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