DK2231598T3 - Nye diazeniumdiolatderivater, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse - Google Patents
Nye diazeniumdiolatderivater, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disseInfo
- Publication number
- DK2231598T3 DK2231598T3 DK08872697.1T DK08872697T DK2231598T3 DK 2231598 T3 DK2231598 T3 DK 2231598T3 DK 08872697 T DK08872697 T DK 08872697T DK 2231598 T3 DK2231598 T3 DK 2231598T3
- Authority
- DK
- Denmark
- Prior art keywords
- derivatives
- processes
- preparation
- new
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Child & Adolescent Psychology (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Endocrinology (AREA)
- Ophthalmology & Optometry (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0708604A FR2924713B1 (fr) | 2007-12-11 | 2007-12-11 | Nouveaux derives diazeniumdiolates, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| PCT/FR2008/001716 WO2009103875A1 (fr) | 2007-12-11 | 2008-12-10 | Nouveaux derives diazeniumdiolates, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2231598T3 true DK2231598T3 (da) | 2011-12-05 |
Family
ID=39158541
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK08872697.1T DK2231598T3 (da) | 2007-12-11 | 2008-12-10 | Nye diazeniumdiolatderivater, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US8288433B2 (da) |
| EP (1) | EP2231598B1 (da) |
| JP (1) | JP5247814B2 (da) |
| KR (1) | KR20100083195A (da) |
| CN (1) | CN101910128B (da) |
| AR (1) | AR069643A1 (da) |
| AT (1) | ATE520658T1 (da) |
| AU (1) | AU2008351147B2 (da) |
| BR (1) | BRPI0822066A2 (da) |
| CA (1) | CA2707853C (da) |
| DK (1) | DK2231598T3 (da) |
| EA (1) | EA201000885A1 (da) |
| ES (1) | ES2371699T3 (da) |
| FR (1) | FR2924713B1 (da) |
| GE (1) | GEP20135733B (da) |
| HR (1) | HRP20110755T1 (da) |
| MA (1) | MA31901B1 (da) |
| MX (1) | MX2010006446A (da) |
| MY (1) | MY147973A (da) |
| NZ (1) | NZ586070A (da) |
| PL (1) | PL2231598T3 (da) |
| PT (1) | PT2231598E (da) |
| RS (1) | RS52001B (da) |
| SI (1) | SI2231598T1 (da) |
| UA (1) | UA97035C2 (da) |
| WO (1) | WO2009103875A1 (da) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8354394B2 (en) * | 2009-10-29 | 2013-01-15 | Merck Sharp & Dohme Corp. | Diuretics |
| EP2533644B1 (en) | 2010-02-12 | 2017-01-18 | Merck Sharp & Dohme Corp. | Diazeniumdiolate cyclopentyl derivatives |
| WO2011146371A1 (en) | 2010-05-21 | 2011-11-24 | Merck Sharp & Dohme Corp. | Diazeniumdiolate cyclohexyl derivatives |
| WO2012058203A1 (en) | 2010-10-29 | 2012-05-03 | Merck Sharp & Dohme Corp. | Diazeniumdiolate heterocyclic derivatives |
| JO3350B1 (ar) | 2011-03-07 | 2019-03-13 | Merck Sharp & Dohme | مشتقات حلقية غير متجانسة محتوية على مجموعات أمينو أولية ومركبات داي أزينيومديولات |
| US9272987B2 (en) | 2011-05-02 | 2016-03-01 | Merck Sharp & Dohme Corp. | Diazeniumdiolate cyclohexyl derivatives |
| CN109608371B (zh) * | 2019-01-16 | 2020-12-29 | 泰州学院 | O2-4-(3-(4-胺磺酰基苯基)脲)苯基偶氮鎓二醇盐衍生物、制备方法及用途 |
| CN114805183B (zh) * | 2022-05-07 | 2022-12-27 | 武汉科技大学 | 一类no供体型荜茇酰胺衍生物、制备方法及用途 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1203691A (en) * | 1968-03-06 | 1970-09-03 | Science Union & Cie | New disubstituted n-amino indoline derivatives and process for preparing them |
| JPH0233030B2 (ja) * | 1982-01-18 | 1990-07-25 | Mitsui Toatsu Chemicals | Surufuamoiruansokukosanjudotaioyobisoreojukoseibuntoshitefukumuchiryoyososeibutsu |
| JPH07118231A (ja) * | 1993-10-22 | 1995-05-09 | Nippon Oil & Fats Co Ltd | スルファモイル安息香酸誘導体 |
| US5958427A (en) * | 1996-11-08 | 1999-09-28 | Salzman; Andrew L. | Nitric oxide donor compounds and pharmaceutical compositions for pulmonary hypertension and other indications |
| AUPS236902A0 (en) * | 2002-05-16 | 2002-06-13 | Northern Sydney Area Health Service | Composition and method for treating hypertension |
| JP2008520578A (ja) * | 2004-11-15 | 2008-06-19 | ニトロメッド インコーポレーティッド | 複素環式の酸化窒素供与体基を含む利尿化合物、組成物および使用方法 |
| JP2008531579A (ja) * | 2005-02-24 | 2008-08-14 | ニトロメッド インコーポレーティッド | 酸化窒素増強利尿化合物、組成物および使用方法 |
| EP2244575B1 (en) * | 2008-01-24 | 2013-07-17 | Merck Sharp & Dohme Corp. | Angiotensin ii receptor antagonists |
| CA2711461A1 (en) * | 2008-02-08 | 2009-08-13 | Merck Sharp & Dohme Corp. | Angiotensin ii receptor antagonists |
-
2007
- 2007-12-11 FR FR0708604A patent/FR2924713B1/fr not_active Expired - Fee Related
-
2008
- 2008-12-10 US US12/735,048 patent/US8288433B2/en not_active Expired - Fee Related
- 2008-12-10 WO PCT/FR2008/001716 patent/WO2009103875A1/fr active Application Filing
- 2008-12-10 ES ES08872697T patent/ES2371699T3/es active Active
- 2008-12-10 AT AT08872697T patent/ATE520658T1/de active
- 2008-12-10 UA UAA201008615A patent/UA97035C2/ru unknown
- 2008-12-10 JP JP2010537487A patent/JP5247814B2/ja not_active Expired - Fee Related
- 2008-12-10 NZ NZ586070A patent/NZ586070A/en not_active IP Right Cessation
- 2008-12-10 PL PL08872697T patent/PL2231598T3/pl unknown
- 2008-12-10 CA CA2707853A patent/CA2707853C/fr not_active Expired - Fee Related
- 2008-12-10 DK DK08872697.1T patent/DK2231598T3/da active
- 2008-12-10 BR BRPI0822066A patent/BRPI0822066A2/pt not_active IP Right Cessation
- 2008-12-10 GE GEAP200811874A patent/GEP20135733B/en unknown
- 2008-12-10 SI SI200830404T patent/SI2231598T1/sl unknown
- 2008-12-10 AU AU2008351147A patent/AU2008351147B2/en not_active Ceased
- 2008-12-10 EP EP08872697A patent/EP2231598B1/fr active Active
- 2008-12-10 EA EA201000885A patent/EA201000885A1/ru unknown
- 2008-12-10 KR KR1020107012930A patent/KR20100083195A/ko active IP Right Grant
- 2008-12-10 CN CN2008801229307A patent/CN101910128B/zh not_active Expired - Fee Related
- 2008-12-10 MY MYPI2010002633A patent/MY147973A/en unknown
- 2008-12-10 PT PT08872697T patent/PT2231598E/pt unknown
- 2008-12-10 MX MX2010006446A patent/MX2010006446A/es active IP Right Grant
- 2008-12-10 RS RS20110438A patent/RS52001B/en unknown
- 2008-12-11 AR ARP080105371A patent/AR069643A1/es not_active Application Discontinuation
-
2010
- 2010-06-07 MA MA32894A patent/MA31901B1/fr unknown
-
2011
- 2011-10-17 HR HR20110755T patent/HRP20110755T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2707853C (fr) | 2013-02-05 |
| US8288433B2 (en) | 2012-10-16 |
| JP2011506408A (ja) | 2011-03-03 |
| PT2231598E (pt) | 2011-10-11 |
| AU2008351147A1 (en) | 2009-08-27 |
| AR069643A1 (es) | 2010-02-10 |
| US20100286225A1 (en) | 2010-11-11 |
| MY147973A (en) | 2013-02-28 |
| PL2231598T3 (pl) | 2011-12-30 |
| UA97035C2 (ru) | 2011-12-26 |
| NZ586070A (en) | 2012-06-29 |
| BRPI0822066A2 (pt) | 2015-09-22 |
| ATE520658T1 (de) | 2011-09-15 |
| AU2008351147B2 (en) | 2012-04-12 |
| GEP20135733B (en) | 2013-01-25 |
| SI2231598T1 (sl) | 2011-11-30 |
| EP2231598B1 (fr) | 2011-08-17 |
| ES2371699T3 (es) | 2012-01-09 |
| CA2707853A1 (fr) | 2009-08-27 |
| CN101910128A (zh) | 2010-12-08 |
| MX2010006446A (es) | 2010-07-05 |
| CN101910128B (zh) | 2013-01-16 |
| FR2924713B1 (fr) | 2010-01-29 |
| HRP20110755T1 (hr) | 2011-11-30 |
| WO2009103875A1 (fr) | 2009-08-27 |
| FR2924713A1 (fr) | 2009-06-12 |
| EP2231598A1 (fr) | 2010-09-29 |
| KR20100083195A (ko) | 2010-07-21 |
| JP5247814B2 (ja) | 2013-07-24 |
| RS52001B (en) | 2012-04-30 |
| EA201000885A1 (ru) | 2011-02-28 |
| MA31901B1 (fr) | 2010-12-01 |
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