DK219585A - Fremgangsmaade, vektorer og transformanter til ekspression af heterologe polypeptider i gaer - Google Patents

Fremgangsmaade, vektorer og transformanter til ekspression af heterologe polypeptider i gaer Download PDF

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Publication number
DK219585A
DK219585A DK219585A DK219585A DK219585A DK 219585 A DK219585 A DK 219585A DK 219585 A DK219585 A DK 219585A DK 219585 A DK219585 A DK 219585A DK 219585 A DK219585 A DK 219585A
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DK
Denmark
Prior art keywords
herological
transformers
polypeptides
vectors
expression
Prior art date
Application number
DK219585A
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English (en)
Other versions
DK219585D0 (da
Inventor
Thomas Dominick Ingolia
Cheryl Ann Beckage
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK219585D0 publication Critical patent/DK219585D0/da
Publication of DK219585A publication Critical patent/DK219585A/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK219585A 1984-05-18 1985-05-17 Fremgangsmaade, vektorer og transformanter til ekspression af heterologe polypeptider i gaer DK219585A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61178284A 1984-05-18 1984-05-18
US06/640,422 US4745057A (en) 1984-05-18 1984-08-13 Method, vectors and transformants for high expression of heterologous polypeptides in yeast

Publications (2)

Publication Number Publication Date
DK219585D0 DK219585D0 (da) 1985-05-17
DK219585A true DK219585A (da) 1985-11-19

Family

ID=27086594

Family Applications (1)

Application Number Title Priority Date Filing Date
DK219585A DK219585A (da) 1984-05-18 1985-05-17 Fremgangsmaade, vektorer og transformanter til ekspression af heterologe polypeptider i gaer

Country Status (4)

Country Link
US (1) US4745057A (da)
EP (1) EP0161935A3 (da)
DK (1) DK219585A (da)
IL (1) IL75202A0 (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0188920B1 (en) * 1984-12-25 1993-09-29 Dainippon Pharmaceutical Co., Ltd. Interleukin 1 and its derivative
US4996144A (en) * 1985-01-25 1991-02-26 Calgene, Inc. Microassay for detection of DNA and RNA
US5168040A (en) * 1988-03-16 1992-12-01 Schering Corporation Colorimetric assay for detecting fungal cell envelope perturbations
JPH0669365B2 (ja) * 1989-05-22 1994-09-07 株式会社ミドリ十字 アルブミン遺伝子を含むプラスミド、形質転換体、形質転換体の製造方法、アルブミンの製造方法
US5284746A (en) * 1990-02-08 1994-02-08 Zymogenetics, Inc. Methods of producing hybrid G protein-coupled receptors
US5580734A (en) * 1990-07-13 1996-12-03 Transkaryotic Therapies, Inc. Method of producing a physical map contigous DNA sequences
ATE130049T1 (de) * 1990-07-13 1995-11-15 Transkaryotic Therapies Inc Verfahren zum absuchen einer bibliothek.
US5973137A (en) * 1996-02-13 1999-10-26 Gentra Systems, Inc. Low pH RNA isolation reagents, method, and kit
US8183344B2 (en) * 1996-04-24 2012-05-22 University Of Michigan Inactivation resistant factor VIII
US6017694A (en) * 1997-12-19 2000-01-25 American Cyanamid Company Methods of screening for modulators of respiratory syncytial virus matrix protein interaction
WO2000058472A2 (en) 1999-03-31 2000-10-05 The University Of North Carolina At Chapel Hill Isolated dna encoding cullin regulators roc1 and roc2, isolated proteins encoded by the same, and methods utilizing the same
US7101989B1 (en) 1999-07-09 2006-09-05 University Of North Carolina At Chapel Hill DsrA protein and polynucleotides encoding the same
US7009045B2 (en) * 2000-07-14 2006-03-07 Archer-Daniels-Midland Company Transformation systems for flavinogenic yeast
US20050233390A1 (en) * 2003-04-09 2005-10-20 Allen John W Device including a proteinaceous factor, a recombinant proteinaceous factor, and a nucleotide sequence encoding the proteinaceous factor
CA2633661C (en) 2005-12-21 2019-06-04 University Of North Carolina At Chapel Hill Method of producing biologically active vitamin k dependent proteins by recombinant methods
AU2007269233B2 (en) * 2006-06-30 2011-06-09 Cnj Holdings, Inc. Method of producing Factor VIII proteins by recombinant methods
US20090203077A1 (en) * 2006-06-30 2009-08-13 The Regents Of The University Of Michigan Method of producing factor viii proteins by recombinant methods
WO2008134665A1 (en) 2007-04-26 2008-11-06 Inspiration Biopharmaceuticals, Inc. Recombinant vitamin k dependent proteins with high sialic acid content and methods of preparing same
JP2015536148A (ja) 2012-11-20 2015-12-21 ザ・ユニヴァーシティ・オヴ・ノース・キャロライナ・アト・チャペル・ヒル 改変第ｉｘ因子タンパク質についての方法および組成物
EP3253786A4 (en) 2015-02-06 2018-10-17 The University of North Carolina at Chapel Hill Optimized human clotting factor viii gene expression cassettes and their use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ199722A (en) * 1981-02-25 1985-12-13 Genentech Inc Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain

Also Published As

Publication number Publication date
IL75202A0 (en) 1985-09-29
EP0161935A3 (en) 1987-08-19
US4745057A (en) 1988-05-17
DK219585D0 (da) 1985-05-17
EP0161935A2 (en) 1985-11-21

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