DK2149609T3 - Forbedret fremgangsmåde til fremstilling af daptomycin - Google Patents

Forbedret fremgangsmåde til fremstilling af daptomycin

Info

Publication number
DK2149609T3
DK2149609T3 DK08161630.2T DK08161630T DK2149609T3 DK 2149609 T3 DK2149609 T3 DK 2149609T3 DK 08161630 T DK08161630 T DK 08161630T DK 2149609 T3 DK2149609 T3 DK 2149609T3
Authority
DK
Denmark
Prior art keywords
daptomycin
improved process
preparation
decanal
fermentation
Prior art date
Application number
DK08161630.2T
Other languages
English (en)
Inventor
Gianluca Bertetti
Antonella Malcangi
Roberto Muraca
Alessia Rossi
Guido Trione
Original Assignee
Olon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Olon Spa filed Critical Olon Spa
Application granted granted Critical
Publication of DK2149609T3 publication Critical patent/DK2149609T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK08161630.2T 2008-08-01 2008-08-01 Forbedret fremgangsmåde til fremstilling af daptomycin DK2149609T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP08161630A EP2149609B1 (en) 2008-08-01 2008-08-01 Improved process for the production of daptomycin

Publications (1)

Publication Number Publication Date
DK2149609T3 true DK2149609T3 (da) 2011-05-16

Family

ID=40162500

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08161630.2T DK2149609T3 (da) 2008-08-01 2008-08-01 Forbedret fremgangsmåde til fremstilling af daptomycin

Country Status (13)

Country Link
US (1) US8313922B2 (da)
EP (1) EP2149609B1 (da)
AT (1) ATE503020T1 (da)
CA (1) CA2674257C (da)
CY (1) CY1111777T1 (da)
DE (1) DE602008005731D1 (da)
DK (1) DK2149609T3 (da)
ES (1) ES2359378T3 (da)
HR (1) HRP20110410T1 (da)
IL (1) IL200172A (da)
PL (1) PL2149609T3 (da)
PT (1) PT2149609E (da)
SI (1) SI2149609T1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102796680B (zh) * 2012-07-04 2018-06-05 鲁南新时代生物技术有限公司 一种玫瑰孢链霉菌及其利用组合前体生产达托霉素的方法
CN103695511A (zh) * 2013-12-05 2014-04-02 成都雅途生物技术有限公司 一种发酵生产达托霉素的方法
CN103695509A (zh) * 2013-12-05 2014-04-02 成都雅途生物技术有限公司 一种流加癸醛发酵生产达托霉素的方法
CN103695510A (zh) * 2013-12-05 2014-04-02 成都雅途生物技术有限公司 一种流加油酸甲酯发酵生产达托霉素的方法
KR101580370B1 (ko) * 2013-12-18 2015-12-23 동국제약 주식회사 신규한 스트렙토마이세스 필라멘토서스 변이주 및 이를 이용한 답토마이신의 생산 방법
KR101716879B1 (ko) * 2014-11-19 2017-03-17 주식회사 종근당바이오 데카노일 글리세라이드를 이용한 답토마이신의 생산방법
IT201600127655A1 (it) 2016-12-16 2018-06-16 Gnosis Spa Processo per la purificazione di antibiotici lipopolipeptidici
CN108342435A (zh) * 2017-01-22 2018-07-31 江苏恒瑞医药股份有限公司 一种发酵制备达托霉素的方法
CN109593808B (zh) * 2017-09-30 2022-10-04 上海医药工业研究院 达托霉素发酵培养基及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4331594A (en) 1978-10-16 1982-05-25 Eli Lilly And Company A-21978 Antibiotics and process for their production
US4885243A (en) 1984-10-09 1989-12-05 Eli Lilly And Company Process for producing A-21978C derivatives
US4800157A (en) 1985-09-09 1989-01-24 Eli Lilly And Company Process for producing the A-21978C antibiotics

Also Published As

Publication number Publication date
PT2149609E (pt) 2011-04-14
IL200172A0 (en) 2010-05-31
ES2359378T3 (es) 2011-05-23
PL2149609T3 (pl) 2011-08-31
CA2674257C (en) 2016-04-19
EP2149609A1 (en) 2010-02-03
SI2149609T1 (sl) 2011-06-30
HRP20110410T1 (hr) 2011-06-30
IL200172A (en) 2011-12-29
DE602008005731D1 (de) 2011-05-05
ATE503020T1 (de) 2011-04-15
CY1111777T1 (el) 2015-10-07
CA2674257A1 (en) 2010-02-01
EP2149609B1 (en) 2011-03-23
US8313922B2 (en) 2012-11-20
US20100047873A1 (en) 2010-02-25

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