DK210690A - Metoder og praeparater til inhibering af blodpladeaggregation - Google Patents

Metoder og praeparater til inhibering af blodpladeaggregation Download PDF

Info

Publication number
DK210690A
DK210690A DK210690A DK210690A DK210690A DK 210690 A DK210690 A DK 210690A DK 210690 A DK210690 A DK 210690A DK 210690 A DK210690 A DK 210690A DK 210690 A DK210690 A DK 210690A
Authority
DK
Denmark
Prior art keywords
inhibitation
preparations
methods
platelet aggregation
platelet
Prior art date
Application number
DK210690A
Other languages
Danish (da)
English (en)
Other versions
DK210690D0 (da
Inventor
John M Maraganore
Joseph A Jakubowski
Original Assignee
Biogen Inc
Univ Boston
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Inc, Univ Boston filed Critical Biogen Inc
Publication of DK210690D0 publication Critical patent/DK210690D0/da
Publication of DK210690A publication Critical patent/DK210690A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK210690A 1988-12-05 1990-09-03 Metoder og praeparater til inhibering af blodpladeaggregation DK210690A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28061888A 1988-12-05 1988-12-05
PCT/US1989/000849 WO1990006128A1 (en) 1988-12-05 1989-03-02 Methods and compositions for inhibiting platelet aggregation

Publications (2)

Publication Number Publication Date
DK210690D0 DK210690D0 (da) 1990-09-03
DK210690A true DK210690A (da) 1991-06-03

Family

ID=23073872

Family Applications (1)

Application Number Title Priority Date Filing Date
DK210690A DK210690A (da) 1988-12-05 1990-09-03 Metoder og praeparater til inhibering af blodpladeaggregation

Country Status (7)

Country Link
EP (1) EP0372670A3 (de)
JP (1) JPH04503660A (de)
AU (1) AU623882B2 (de)
DK (1) DK210690A (de)
FI (1) FI904329A0 (de)
HU (1) HUT57060A (de)
WO (1) WO1990006128A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5196403A (en) * 1989-01-27 1993-03-23 Biogen, Inc. Method of inhibiting platelet activation
IT1243358B (it) * 1990-07-23 1994-06-10 Iketon Farmaceutici Srl Composizioni farmaceutiche per la somministrazione orale di irudina
US5242810A (en) * 1990-12-07 1993-09-07 Biogen, Inc. Bifunctional inhibitors of thrombin and platelet activation
DE4103649A1 (de) * 1991-02-07 1992-08-13 Basf Ag Neue antikoagulatorisch wirksame peptide
US5767235A (en) * 1991-03-05 1998-06-16 Nippon Mining Company Limited Anticoagulant hirudin variants and methods for their production
ATE142642T1 (de) * 1991-03-05 1996-09-15 Japan Energy Corp Hirudinanalog oder dessen salz, dessen herstellung und das als aktiven bestandteil enthaltende antikoagulanz
US5837808A (en) * 1991-08-20 1998-11-17 Baxter International Inc. Analogs of hirudin
NZ244778A (en) * 1991-10-21 1994-03-25 Ortho Pharma Corp Peg imidates and protein derivatives thereof
CA2131389A1 (en) * 1992-03-02 1993-09-16 John M. Maraganore Thrombin receptor antagonists
GB9209032D0 (en) * 1992-04-25 1992-06-10 Ciba Geigy Ag New peptide derivatives
BR9306984A (pt) * 1992-08-27 1999-01-12 Deakin Res Ltd Análogo de antígeno de peptídeo de um antígeno de peptídeo nativo vacina anticorpo processo para vacinar um hospedeiro necessitando deste tratamento estojo diagnóstico processos para preparar um análogo de um antiígeno de um antígeno de peptídeo nativo para preparar uma vacina para analisar uma amostra para um antígeno de peptídeo nativo e para analisar uma amostra para um anticorpo
CN1124964A (zh) * 1993-06-11 1996-06-19 默里尔药物公司 三功能抗凝血酶和抗血小板的肽
KR100445309B1 (ko) * 1993-07-01 2004-11-12 메르크 파텐트 게엠베하 콜라겐-자극혈소판응집에대한억제제
US5622867A (en) * 1994-10-19 1997-04-22 Lifecell Corporation Prolonged preservation of blood platelets
US6221669B1 (en) 1994-10-19 2001-04-24 Lifecell Corporation Prolonged preservation of blood platelets
US7112661B1 (en) 1998-10-30 2006-09-26 The Research Foundation Of State University Of New York Variable heavy chain and variable light chain regions of antibodies to human platelet glycoprotein Ib alpha
US6809076B2 (en) 2000-03-20 2004-10-26 Abbott Gmbh & Co. Kg Use of anticoagulant agents in the extracorporeal treatment of blood
EP1265639A1 (de) * 2000-03-20 2002-12-18 Knoll GmbH Verwendung koagulationshemmender wirkstoffe bei der extrakorporalen behandlung von blut
WO2006000081A1 (en) * 2004-06-23 2006-01-05 National Research Council Of Canada Polypeptide ligands containing linkers
AU2006294654B2 (en) 2005-09-26 2012-05-24 Lifecell Corporation Dry platelet composition
US7691839B2 (en) 2005-09-28 2010-04-06 Biovascular, Inc. Methods and compositions for blocking platelet and cell adhesion, cell migration and inflammation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3342139A1 (de) * 1983-11-22 1985-05-30 Ciba-Geigy Ag, Basel Desulfatohirudine, verfahren zu ihrer herstellung und pharmazeutische mittel
US4683291A (en) * 1985-10-28 1987-07-28 Scripps Clinic And Research Foundation Platelet binding inhibitors
US4702908A (en) * 1985-11-01 1987-10-27 Thorbecke G Jeanette Composition containing platelet factor 4 and method for restoring suppressed immune responses
CA1341032C (en) * 1987-01-23 2000-06-20 John L. Krstenansky Anticoagulant peptides
EP0333356A3 (de) * 1988-03-04 1990-12-19 Biogen, Inc. Hirudin-Peptide

Also Published As

Publication number Publication date
EP0372670A2 (de) 1990-06-13
HUT57060A (en) 1991-11-28
AU3098189A (en) 1990-06-07
FI904329A0 (fi) 1990-09-03
AU623882B2 (en) 1992-05-28
WO1990006128A1 (en) 1990-06-14
EP0372670A3 (de) 1991-08-21
JPH04503660A (ja) 1992-07-02
DK210690D0 (da) 1990-09-03

Similar Documents

Publication Publication Date Title
DK210690D0 (da) Metoder og praeparater til inhibering af blodpladeaggregation
DK33287A (da) Imidazolanaloge af mevalonolacton og derivater deraf
DK170187A (da) Pharmaceutisk fordelagtigt salt af amlodipin og farmaceutiske praeparater indeholdende dette
NO20000369L (no) Fremstilling av ribozymer og preparater omfattende slike
DK0448930T3 (da) Stabile præparater til parenteral administration og fremgangsmåde til fremstilling deraf
DK299087D0 (da) Proteins and derivatives thereof
NO875232L (no) Stabile preparater av ricin-toksin-a-kjede og av rta-immunokonjugater og stabilisator-utsorteringsmetoder derav.
NO165494C (no) Aminosalter av lignosulfonater og anvendelse derav.
DK56891D0 (da) Anvendelse af pesticidpraeparater
DK430189D0 (da) Fremgangsmaade til fremstilling af et aromatiseringsmiddel og det fremstillede middel
DK94686D0 (da) Nye oxadiazolylimidazobenzodiazepinderivater og fremgangsmaader til fremstilling af samme
DK203589A (da) Pyridylthiazolidincarboxamidderiivater og mellemprodukter herfor, praeparater indeholdende foerstnaevnte forbindelser samt fremgangsmaade til fremstilling af begge forbindelser
DK270988A (da) Nitrogenholdige derivater af epipodophyllotoxinglucosider
DK130390D0 (da) Praeparat af i prokaryonter udtrykt plasminogenaktivator
DK69387A (da) Cyanoderivater og fremgangsmaade til fremstilling deraf samt midler indeholdende derivaterne
DK422984D0 (da) Aminocyklopentaner og farmaceutiske praeparater deraf
DK701588A (da) N-hydroxy-5-phenyl-2-furancarboximidamider og anvendelse heraf til fremstilling af farmceutiske praeparater
DK120689A (da) Komplekser af selen- og tellurderivater
DK335386D0 (da) Embonater af quinoloncarboxylsyrer og derivater deraf
DK162607C (da) Azopigmentpraeparater og deres anvendelse
DK343988A (da) Praeparater med kontrolleret afgivelseshastighed af nulte orden, og fremgangsmaade til fremstilling af saasanne praeparater
DK119488D0 (da) Mono- og diepoxidderivater af 23-deoxy-ll-f28249-forbindelser
DK163994C (da) 1-phenoxy-2-hydroxy-3-aminopropanderivater, farmaceutisk praeparat indeholdende derivaterne og anvendelse af derivaterne
DK614689D0 (da) Fremgangsmaade til fraskillelse og koncentrering af apolipoproteiner
DK75691A (da) Ny farmaceutisk anvendelse af fusidin og derivater deraf

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment