ATE142642T1 - Hirudinanalog oder dessen salz, dessen herstellung und das als aktiven bestandteil enthaltende antikoagulanz - Google Patents
Hirudinanalog oder dessen salz, dessen herstellung und das als aktiven bestandteil enthaltende antikoagulanzInfo
- Publication number
- ATE142642T1 ATE142642T1 AT92905744T AT92905744T ATE142642T1 AT E142642 T1 ATE142642 T1 AT E142642T1 AT 92905744 T AT92905744 T AT 92905744T AT 92905744 T AT92905744 T AT 92905744T AT E142642 T1 ATE142642 T1 AT E142642T1
- Authority
- AT
- Austria
- Prior art keywords
- glu
- tyr
- active ingredient
- salt
- production
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Electrotherapy Devices (AREA)
- Materials For Medical Uses (AREA)
- Saccharide Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6390991 | 1991-03-05 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE142642T1 true ATE142642T1 (de) | 1996-09-15 |
Family
ID=13242934
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT92905744T ATE142642T1 (de) | 1991-03-05 | 1992-03-04 | Hirudinanalog oder dessen salz, dessen herstellung und das als aktiven bestandteil enthaltende antikoagulanz |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0531537B1 (de) |
AT (1) | ATE142642T1 (de) |
AU (1) | AU660171B2 (de) |
CA (1) | CA2081305A1 (de) |
DE (1) | DE69213628T2 (de) |
FI (1) | FI924937A (de) |
WO (1) | WO1992015610A1 (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2687681B1 (fr) * | 1992-02-20 | 1995-10-13 | Transgene Sa | Conjugues polyethyleneglycol-hirudine, leur procede de preparation et leur emploi pour le traitement des thromboses. |
DE50215004D1 (de) | 2001-09-10 | 2011-05-26 | Novel Science Internat Gmbh | Organische verbindungen mit biologischer wirkung als thrombinhemmer und ihre verwendung |
CN113789293B (zh) * | 2021-11-16 | 2022-03-15 | 江苏省中国科学院植物研究所 | 一种高产天然水蛭素的大肠杆菌工程菌株及其应用 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1341032C (en) * | 1987-01-23 | 2000-06-20 | John L. Krstenansky | Anticoagulant peptides |
JPH04503660A (ja) * | 1988-12-05 | 1992-07-02 | バイオジェン インコーポレイテッド | 血小板凝集抑制の方法及び組成物 |
AU6070590A (en) * | 1989-07-20 | 1991-02-22 | Biogen, Inc. | Hirudin peptide derivatives |
ZA907742B (en) * | 1989-10-03 | 1991-07-31 | Merrell Dow Pharma | Anticoagulant peptides |
CA2035917C (en) * | 1990-02-13 | 2001-10-02 | John L. Krstenansky | Stabilized sulfonate, sulfate, phosphonate and phosphate derivatives of hirudin |
-
1992
- 1992-03-04 AT AT92905744T patent/ATE142642T1/de not_active IP Right Cessation
- 1992-03-04 CA CA002081305A patent/CA2081305A1/en not_active Abandoned
- 1992-03-04 EP EP92905744A patent/EP0531537B1/de not_active Expired - Lifetime
- 1992-03-04 AU AU13616/92A patent/AU660171B2/en not_active Ceased
- 1992-03-04 DE DE69213628T patent/DE69213628T2/de not_active Expired - Fee Related
- 1992-03-04 WO PCT/JP1992/000253 patent/WO1992015610A1/ja active IP Right Grant
- 1992-10-30 FI FI924937A patent/FI924937A/fi not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
FI924937A0 (fi) | 1992-10-30 |
EP0531537A4 (de) | 1992-12-30 |
CA2081305A1 (en) | 1992-09-06 |
WO1992015610A1 (fr) | 1992-09-17 |
DE69213628D1 (de) | 1996-10-17 |
AU660171B2 (en) | 1995-06-15 |
EP0531537A1 (de) | 1993-03-17 |
FI924937A (fi) | 1992-10-30 |
DE69213628T2 (de) | 1997-04-24 |
EP0531537B1 (de) | 1996-09-11 |
AU1361692A (en) | 1992-10-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |