DK209784A - Prolinderivater - Google Patents
Prolinderivater Download PDFInfo
- Publication number
- DK209784A DK209784A DK209784A DK209784A DK209784A DK 209784 A DK209784 A DK 209784A DK 209784 A DK209784 A DK 209784A DK 209784 A DK209784 A DK 209784A DK 209784 A DK209784 A DK 209784A
- Authority
- DK
- Denmark
- Prior art keywords
- proline
- Prior art date
Links
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1019—Tetrapeptides with the first amino acid being basic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06086—Dipeptides with the first amino acid being basic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0815—Tripeptides with the first amino acid being basic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB838311423A GB8311423D0 (en) | 1983-04-27 | 1983-04-27 | Proline derivatives |
| GB838314708A GB8314708D0 (en) | 1983-05-27 | 1983-05-27 | Proline derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK209784D0 DK209784D0 (da) | 1984-04-26 |
| DK209784A true DK209784A (da) | 1984-10-28 |
Family
ID=26285956
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK209784A DK209784A (da) | 1983-04-27 | 1984-04-26 | Prolinderivater |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US4596789A (cs) |
| EP (1) | EP0124317B1 (cs) |
| AU (1) | AU580955B2 (cs) |
| CA (1) | CA1253297A (cs) |
| DE (1) | DE3481913D1 (cs) |
| DK (1) | DK209784A (cs) |
| ES (2) | ES8701154A1 (cs) |
| FI (1) | FI841601A7 (cs) |
| GR (1) | GR81937B (cs) |
| HU (1) | HUT34041A (cs) |
| IE (1) | IE57350B1 (cs) |
| IL (1) | IL71614A0 (cs) |
| NO (1) | NO841665L (cs) |
| NZ (1) | NZ207965A (cs) |
| PT (1) | PT78502B (cs) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1267499A (en) * | 1983-07-12 | 1990-04-03 | Cedric H. Hassall | Peptide amides and aldehydes |
| DD248961A1 (de) * | 1984-05-22 | 1987-08-26 | Akad Wissenschaften Ddr | Verfahren zur herstellung wundheilungsfoerdernder praeparationen |
| GB8600263D0 (en) * | 1985-01-22 | 1986-02-12 | Ici America Inc | Peptide derivatives |
| US5194588A (en) * | 1985-01-22 | 1993-03-16 | Ici Americas Inc. | Aminoalcohol intermediates for peptide derivatives |
| US5055450A (en) * | 1985-01-22 | 1991-10-08 | Ici Americas Inc. | Peptide derivatives |
| ATE71934T1 (de) | 1985-06-07 | 1992-02-15 | Ici America Inc | Selektionierte difluorverbindungen. |
| GB8613704D0 (en) * | 1986-06-05 | 1986-07-09 | Ici America Inc | Difluoro keto compounds |
| DE3751570T2 (de) * | 1986-06-05 | 1996-04-18 | Zeneca Inc | Difluoro-Peptid-Verbindungen. |
| EP0249349B1 (en) * | 1986-06-05 | 1992-10-14 | Ici Americas Inc. | Difluoroketo compounds |
| GB8809316D0 (en) * | 1987-05-11 | 1988-05-25 | Ici America Inc | Heterocyclic ketones |
| JPH075634B2 (ja) * | 1987-10-30 | 1995-01-25 | 日東紡績株式会社 | トリペプチド類及びこれを含有する抗プラスミン剤 |
| FR2622581B1 (fr) * | 1987-11-03 | 1990-02-16 | Inorgan Sa Rech Develop Pharm | Nouveaux derives de l-proline, leur preparation et leurs applications biologiques |
| US5736520A (en) * | 1988-10-07 | 1998-04-07 | Merrell Pharmaceuticals Inc. | Peptidase inhibitors |
| ZA897515B (en) * | 1988-10-07 | 1990-06-27 | Merrell Dow Pharma | Novel peptidase inhibitors |
| JPH03503055A (ja) * | 1988-10-27 | 1991-07-11 | ユニバーシティー オブ ケンタッキー リサーチ ファウンデーション | 人の白血球エラスターゼ阻害剤およびその製造方法およびその使用 |
| EP0490379A3 (de) * | 1990-12-13 | 1992-06-24 | BERLIN-CHEMIE Aktiengesellschaft | Diaminosäurederivate und pharmazeutische Zusammensetzungen |
| CA2071621C (en) * | 1991-06-19 | 1996-08-06 | Ahihiko Hosoda | Aldehyde derivatives |
| IL108031A0 (en) * | 1992-12-22 | 1994-04-12 | Procter & Gamble | Difluoro pentapeptide derivatives and pharmaceutical compositions containing them |
| FR2700165B1 (fr) * | 1993-01-07 | 1995-02-17 | Rhone Poulenc Rorer Sa | Dérivés de pyrrolidine, leur préparation et les médicaments les contenant. |
| FR2700166B1 (fr) * | 1993-01-07 | 1995-02-17 | Rhone Poulenc Rorer Sa | Dérivés de pyrrolidine, leur préparation et les médicaments les contenant. |
| US5436229A (en) * | 1994-03-04 | 1995-07-25 | Eli Lilly And Company | Bisulfite adducts of arginine aldehydes |
| GB9502152D0 (en) * | 1995-02-03 | 1995-03-29 | Zeneca Ltd | Proline derivatives |
| DE69637307T2 (de) * | 1995-11-28 | 2008-02-28 | Cephalon, Inc. | Aus d-aminosäuren abgeleitete cystein-und serinproteasehemmer |
| US6348448B1 (en) | 1997-04-18 | 2002-02-19 | Cephalon, Inc. | Peptidyl-2-amino-1-hydroxyalkanesulfonic acid cysteine protease inhibitors |
| US6143715A (en) * | 1997-08-11 | 2000-11-07 | Boehringer Ingelheim (Canada) Ltd. | Hepatitis C inhibitor peptide analogues |
| SK288064B6 (sk) * | 2000-07-21 | 2013-04-03 | Merck Sharp & Dohme Corp. | Peptide compounds, pharmaceutical compositions comprising them and their use |
| EP2163652B2 (en) | 2002-01-28 | 2023-05-31 | Life Technologies Corporation | Preparing crude biological extracts using protease, suitable for preparing cDNA |
| WO2004103996A1 (en) * | 2003-05-21 | 2004-12-02 | Boehringer Ingelheim International Gmbh | Hepatitis c inhibitor compounds |
| UY29016A1 (es) | 2004-07-20 | 2006-02-24 | Boehringer Ingelheim Int | Analogos de dipeptidos inhibidores de la hepatitis c |
| CA2573346C (en) * | 2004-07-20 | 2011-09-20 | Boehringer Ingelheim International Gmbh | Hepatitis c inhibitor peptide analogs |
| US8143426B2 (en) * | 2006-07-24 | 2012-03-27 | Tetralogic Pharmaceuticals Corporation | IAP inhibitors |
| US7964350B1 (en) | 2007-05-18 | 2011-06-21 | Applied Biosystems, Llc | Sample preparation for in situ nucleic acid analysis |
| US20080319221A1 (en) * | 2007-06-22 | 2008-12-25 | Bernd Junker | Esters of Pentahydroxyhexylcarbamoyl Alkanoic Acids |
| DE102007063671A1 (de) * | 2007-11-13 | 2009-06-25 | Sanofi-Aventis Deutschland Gmbh | Neue kristalline Diphenylazetidinonhydrate, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
| US8211637B2 (en) * | 2008-12-19 | 2012-07-03 | Life Technologies Corporation | Proteinase K inhibitors, methods and compositions therefor |
| JP6334396B2 (ja) * | 2011-07-01 | 2018-05-30 | ノボザイムス アクティーゼルスカブ | 安定化スブチリシン組成物 |
| US11161859B2 (en) | 2017-03-21 | 2021-11-02 | The Scripps Research Institute | Cu- and Ni-catalyzed decarboxylative borylation reactions |
| JP2022538360A (ja) * | 2019-07-01 | 2022-09-01 | ビーエーエスエフ ソシエタス・ヨーロピア | 酵素を安定化するためのペプチドアセタール |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE629254C (de) * | 1934-06-28 | 1936-04-25 | Fried Krupp Grusonwerk Akt Ges | Vorrichtung zum Glaetten der Arbeitswalzen eines Walzwerks waehrend des Betriebes |
| US3867364A (en) * | 1968-11-21 | 1975-02-18 | Microbial Chem Res Found | Process for the synthesis of leupeptins and their analogues |
| US3935280A (en) * | 1975-01-10 | 1976-01-27 | Aldrich-Boranes, Inc. | Reduction of amino acids in the presence of boron trifluoride |
| CH629254A5 (en) * | 1976-10-14 | 1982-04-15 | Nippon Kayaku Kk | Process for preparing L-leupeptins |
| HU177098B (en) * | 1979-01-04 | 1981-07-28 | Gyogyszerkutato Intezet | Process for producing new peptidyl-n-carboxy-l-arginin-a |
| HU184368B (en) * | 1981-01-13 | 1984-08-28 | Gyogyszerkutato Intezet | Process for preparing d-phenyl-alanyl-l-propyl-l-arginine-ald ehyde-shulphate |
| CS226907B1 (en) * | 1981-08-07 | 1984-04-16 | Kasafirek Evzen | Alkylamides of carboxyalkanoylpeptides |
| FR2546164B1 (fr) * | 1983-05-16 | 1987-07-17 | Centre Nat Rech Scient | Nouveaux derives de peptides, leur preparation et leur application comme inhibiteurs de l'elastase |
| CA1267499A (en) * | 1983-07-12 | 1990-04-03 | Cedric H. Hassall | Peptide amides and aldehydes |
-
1984
- 1984-04-17 EP EP84302621A patent/EP0124317B1/en not_active Expired
- 1984-04-17 DE DE8484302621T patent/DE3481913D1/de not_active Expired - Fee Related
- 1984-04-19 IE IE985/84A patent/IE57350B1/en not_active IP Right Cessation
- 1984-04-22 IL IL71614A patent/IL71614A0/xx unknown
- 1984-04-24 GR GR74482A patent/GR81937B/el unknown
- 1984-04-24 US US06/603,408 patent/US4596789A/en not_active Expired - Lifetime
- 1984-04-24 FI FI841601A patent/FI841601A7/fi not_active Application Discontinuation
- 1984-04-25 CA CA000452712A patent/CA1253297A/en not_active Expired
- 1984-04-25 HU HU841586A patent/HUT34041A/hu unknown
- 1984-04-26 NZ NZ207965A patent/NZ207965A/en unknown
- 1984-04-26 NO NO841665A patent/NO841665L/no unknown
- 1984-04-26 DK DK209784A patent/DK209784A/da not_active Application Discontinuation
- 1984-04-27 PT PT78502A patent/PT78502B/pt not_active IP Right Cessation
- 1984-04-27 ES ES532007A patent/ES8701154A1/es not_active Expired
- 1984-04-27 AU AU27444/84A patent/AU580955B2/en not_active Ceased
-
1985
- 1985-01-31 ES ES540029A patent/ES8705465A1/es not_active Expired
- 1985-12-06 US US06/806,265 patent/US4691007A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| NO841665L (no) | 1984-10-29 |
| AU2744484A (en) | 1984-11-01 |
| IE840985L (en) | 1984-10-27 |
| ES540029A0 (es) | 1987-05-01 |
| EP0124317B1 (en) | 1990-04-11 |
| EP0124317A3 (en) | 1987-01-14 |
| US4691007A (en) | 1987-09-01 |
| AU580955B2 (en) | 1989-02-09 |
| ES8701154A1 (es) | 1986-11-16 |
| FI841601A0 (fi) | 1984-04-24 |
| FI841601A7 (fi) | 1984-10-28 |
| HUT34041A (en) | 1985-01-28 |
| US4596789A (en) | 1986-06-24 |
| ES8705465A1 (es) | 1987-05-01 |
| PT78502A (en) | 1984-05-01 |
| IE57350B1 (en) | 1992-08-12 |
| DE3481913D1 (de) | 1990-05-17 |
| ES532007A0 (es) | 1986-11-16 |
| GR81937B (cs) | 1984-12-12 |
| IL71614A0 (en) | 1984-07-31 |
| PT78502B (en) | 1986-07-22 |
| CA1253297A (en) | 1989-04-25 |
| NZ207965A (en) | 1987-08-31 |
| EP0124317A2 (en) | 1984-11-07 |
| DK209784D0 (da) | 1984-04-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHS | Application shelved for other reasons than non-payment |