DK204884D0 - Gaerudtrykkelsesmedium,gaerorganisme transformeret dermed og fremgangsmaade til fremstilling af et for gaer heterologt protein - Google Patents

Gaerudtrykkelsesmedium,gaerorganisme transformeret dermed og fremgangsmaade til fremstilling af et for gaer heterologt protein

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Publication number
DK204884D0
DK204884D0 DK2048/84A DK204884A DK204884D0 DK 204884 D0 DK204884 D0 DK 204884D0 DK 2048/84 A DK2048/84 A DK 2048/84A DK 204884 A DK204884 A DK 204884A DK 204884 D0 DK204884 D0 DK 204884D0
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DK
Denmark
Prior art keywords
yas
procedure
preparation
prior
expression medium
Prior art date
Application number
DK2048/84A
Other languages
English (en)
Other versions
DK204884A (da
Inventor
Chung Nan Chang
Ronald Arthur Hitzeman
Mark Douglas Matteucci
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of DK204884D0 publication Critical patent/DK204884D0/da
Publication of DK204884A publication Critical patent/DK204884A/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405Glucanases
    • C12N9/2408Glucanases acting on alpha -1,4-glucosidic bonds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/555Interferons [IFN]
    • C07K14/56IFN-alpha
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/50Fusion polypeptide containing protease site
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
DK204884A 1983-04-25 1984-04-24 Gaerudtrykkelsesmedium, gaerorganisme transformeret dermed og fremgangsmaade til fremstilling af et for gaer heterologt protein DK204884A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US48833783A 1983-04-25 1983-04-25

Publications (2)

Publication Number Publication Date
DK204884D0 true DK204884D0 (da) 1984-04-24
DK204884A DK204884A (da) 1984-12-07

Family

ID=23939341

Family Applications (1)

Application Number Title Priority Date Filing Date
DK204884A DK204884A (da) 1983-04-25 1984-04-24 Gaerudtrykkelsesmedium, gaerorganisme transformeret dermed og fremgangsmaade til fremstilling af et for gaer heterologt protein

Country Status (9)

Country Link
EP (1) EP0127304A1 (da)
JP (1) JPS6041488A (da)
KR (1) KR840008697A (da)
AU (1) AU2721884A (da)
DK (1) DK204884A (da)
ES (1) ES531897A0 (da)
IL (1) IL71620A0 (da)
NZ (1) NZ207925A (da)
ZA (1) ZA843061B (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8334261D0 (en) * 1983-12-22 1984-02-01 Bass Plc Fermentation processes
SU1364343A1 (ru) * 1984-07-13 1988-01-07 Всесоюзный научно-исследовательский институт генетики и селекции промышленных микроорганизмов Способ получени человеческого лейкоцитарного интерферона альфа-2
DE3436818A1 (de) * 1984-10-06 1986-04-10 Hoechst Ag, 6230 Frankfurt Synthetische signalsequenz zum transport von proteinen in expressionssystemen
ATE54167T1 (de) * 1984-12-06 1990-07-15 Fina Research Promotoren fuer die expression von fremden genen in hefe, plasmide, die diese promotoren enthalten, sowie deren verwendung zur herstellung von polypeptiden.
US5198345A (en) * 1985-04-15 1993-03-30 Gist-Brocades N.V. Vectors in use in filamentous fungi
AU606033B2 (en) * 1985-04-15 1991-01-31 Dsm Ip Assets B.V. Promotors of filamentous fungi and use thereof
US5024941A (en) * 1985-12-18 1991-06-18 Biotechnica International, Inc. Expression and secretion vector for yeast containing a glucoamylase signal sequence
CA1339101C (en) * 1986-06-03 1997-07-29 Nicolaas Overbeeke Production of guar alpha-galactosidase and immunologically related alpha-galactosidases by host organisms transformed with recombinant dna methods
EP0255153B1 (en) * 1986-06-03 1995-01-18 Unilever N.V. Production of guar alpha-galactosidase by hosts transformed by recombinant DNA methods
IL83435A (en) * 1986-09-23 1993-01-14 Miles Lab Dna construct for expression of genes in yeast, an expression vector containing it and yeast transformed with said expression vector
DE3635867A1 (de) * 1986-10-22 1988-05-11 Boehringer Ingelheim Int Neue hefeexpressionsvektoren fuer ifn-omega, verfahren zu ihrer herstellung und deren verwendung
JPH01240191A (ja) * 1988-02-16 1989-09-25 Green Cross Corp:The 酵母で機能する新規シグナルペプチドおよびこれを用いた異種蛋白質の分泌発現
JP3092811B2 (ja) * 1988-07-23 2000-09-25 デルタ バイオテクノロジー リミテッド ペプチドおよびdna配列
CU22722A1 (es) * 1996-10-03 2002-02-28 Ct Ingenieria Genetica Biotech Sistema de transformación para la expresión de genes heterólogos en la levadura candida utilis
US6265186B1 (en) 1997-04-11 2001-07-24 Dsm N.V. Yeast cells comprising at least two copies of a desired gene integrated into the chromosomal genome at more than one non-ribosomal RNA encoding domain, particularly with Kluyveromyces
WO2007148840A1 (en) 2006-06-20 2007-12-27 Mogam Biotechnology Research Institute Methods for enhancing a secretion efficiency of recombinant foreign protein in yeast expression system

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4775622A (en) * 1982-03-08 1988-10-04 Genentech, Inc. Expression, processing and secretion of heterologous protein by yeast

Also Published As

Publication number Publication date
DK204884A (da) 1984-12-07
AU2721884A (en) 1984-11-01
ES8602137A1 (es) 1985-12-01
EP0127304A1 (en) 1984-12-05
ES531897A0 (es) 1985-12-01
ZA843061B (en) 1984-11-28
NZ207925A (en) 1988-05-30
IL71620A0 (en) 1984-07-31
JPS6041488A (ja) 1985-03-05
KR840008697A (ko) 1984-12-17

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