DK2044020T3 - Krystallinske former af 4-[2-(4-methylphenylsulfanyl)-phenyl]-piperidin med kombineret serotonin- og norepinephrin-genoptagelsesinhibering til behandling af neuropatisk smerte - Google Patents
Krystallinske former af 4-[2-(4-methylphenylsulfanyl)-phenyl]-piperidin med kombineret serotonin- og norepinephrin-genoptagelsesinhibering til behandling af neuropatisk smerteInfo
- Publication number
- DK2044020T3 DK2044020T3 DK07764496.1T DK07764496T DK2044020T3 DK 2044020 T3 DK2044020 T3 DK 2044020T3 DK 07764496 T DK07764496 T DK 07764496T DK 2044020 T3 DK2044020 T3 DK 2044020T3
- Authority
- DK
- Denmark
- Prior art keywords
- methylphenylsulfanyl
- piperidine
- phenyl
- neuropathic pain
- crystalline forms
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4465—Non condensed piperidines, e.g. piperocaine only substituted in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/24—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one carboxyl group bound to the carbon skeleton, e.g. aspartic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C55/00—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
- C07C55/02—Dicarboxylic acids
- C07C55/08—Malonic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C55/00—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
- C07C55/02—Dicarboxylic acids
- C07C55/12—Glutaric acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
- C07C59/08—Lactic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US80500906P | 2006-06-16 | 2006-06-16 | |
DKPA200600816 | 2006-06-16 | ||
DKPA200700423 | 2007-03-20 | ||
PCT/DK2007/050076 WO2007144006A1 (en) | 2006-06-16 | 2007-06-15 | Crystalline forms of 4- [2- (4-methylphenylsulfanyl) -phenyl] piperidine with combined serotonin and norepinephrine reuptake inhibition for the treatment of neuropathic pain |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2044020T3 true DK2044020T3 (da) | 2011-08-15 |
Family
ID=39722478
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK07764496.1T DK2044020T3 (da) | 2006-06-16 | 2007-06-15 | Krystallinske former af 4-[2-(4-methylphenylsulfanyl)-phenyl]-piperidin med kombineret serotonin- og norepinephrin-genoptagelsesinhibering til behandling af neuropatisk smerte |
Country Status (15)
Country | Link |
---|---|
JP (1) | JP2014098017A (da) |
KR (1) | KR101472595B1 (da) |
AR (1) | AR061480A1 (da) |
AT (1) | ATE508115T1 (da) |
BR (1) | BRPI0712758A2 (da) |
CA (1) | CA2784304A1 (da) |
DE (1) | DE602007014372D1 (da) |
DK (1) | DK2044020T3 (da) |
MY (1) | MY150698A (da) |
NZ (1) | NZ572856A (da) |
PT (1) | PT2044020E (da) |
RS (1) | RS51687B (da) |
SI (1) | SI2044020T1 (da) |
TN (1) | TNSN08461A1 (da) |
TW (1) | TWI444365B (da) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101972931B1 (ko) | 2017-10-19 | 2019-04-26 | 재단법인대구경북과학기술원 | 풍선 타입 피질전도 측정장치 및 이의 제조방법 |
CN116930385B (zh) * | 2023-08-08 | 2024-02-20 | 北京爱思益普生物科技股份有限公司 | 一种高盐浓度制剂中化合物浓度的测定方法 |
CN117305360A (zh) * | 2023-09-15 | 2023-12-29 | 江南大学 | 一种哺乳动物细胞核转染液及其制备方法和在细胞核内递送的应用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UA81749C2 (uk) * | 2001-10-04 | 2008-02-11 | Х. Луннбек А/С | Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну |
JP5318757B2 (ja) * | 2006-06-16 | 2013-10-16 | ハー・ルンドベック・アクチエゼルスカベット | 神経因性疼痛の治療のための、組み合わされたセロトニンおよびノルエピネフリン再取り込み阻害を有する4−[2−(4−メチルフェニルスルファニル)−フェニル]ピペリジンの結晶形 |
-
2007
- 2007-06-15 AT AT07764496T patent/ATE508115T1/de active
- 2007-06-15 SI SI200730594T patent/SI2044020T1/sl unknown
- 2007-06-15 DE DE602007014372T patent/DE602007014372D1/de active Active
- 2007-06-15 NZ NZ572856A patent/NZ572856A/en not_active IP Right Cessation
- 2007-06-15 MY MYPI20084894 patent/MY150698A/en unknown
- 2007-06-15 CA CA2784304A patent/CA2784304A1/en not_active Abandoned
- 2007-06-15 BR BRPI0712758-8A patent/BRPI0712758A2/pt not_active IP Right Cessation
- 2007-06-15 PT PT07764496T patent/PT2044020E/pt unknown
- 2007-06-15 AR ARP070102640A patent/AR061480A1/es unknown
- 2007-06-15 DK DK07764496.1T patent/DK2044020T3/da active
- 2007-06-15 RS RS20110223A patent/RS51687B/en unknown
- 2007-06-20 TW TW096121999A patent/TWI444365B/zh not_active IP Right Cessation
-
2008
- 2008-11-17 TN TNP2008000461A patent/TNSN08461A1/en unknown
- 2008-12-11 KR KR1020087030260A patent/KR101472595B1/ko not_active IP Right Cessation
-
2014
- 2014-02-03 JP JP2014018411A patent/JP2014098017A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
BRPI0712758A2 (pt) | 2012-09-25 |
ATE508115T1 (de) | 2011-05-15 |
TNSN08461A1 (en) | 2010-04-14 |
AR061480A1 (es) | 2008-08-27 |
JP2014098017A (ja) | 2014-05-29 |
TWI444365B (zh) | 2014-07-11 |
KR101472595B1 (ko) | 2014-12-15 |
SI2044020T1 (sl) | 2011-06-30 |
TW200817329A (en) | 2008-04-16 |
PT2044020E (pt) | 2011-05-12 |
DE602007014372D1 (de) | 2011-06-16 |
KR20090018630A (ko) | 2009-02-20 |
MY150698A (en) | 2014-02-28 |
CA2784304A1 (en) | 2007-12-21 |
RS51687B (en) | 2011-10-31 |
NZ572856A (en) | 2012-02-24 |
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