DK2032593T3 - Aminoderivater af B-homoandrostaner og B-heteroandrostaner - Google Patents

Aminoderivater af B-homoandrostaner og B-heteroandrostaner

Info

Publication number
DK2032593T3
DK2032593T3 DK07729767.9T DK07729767T DK2032593T3 DK 2032593 T3 DK2032593 T3 DK 2032593T3 DK 07729767 T DK07729767 T DK 07729767T DK 2032593 T3 DK2032593 T3 DK 2032593T3
Authority
DK
Denmark
Prior art keywords
homoandrostanes
heteroandrostanes
amino derivatives
derivatives
amino
Prior art date
Application number
DK07729767.9T
Other languages
English (en)
Inventor
Alberto Cerri
Barbara Moro
Maco Torri
Giulio Carzana
Giuseppe Bianchi
Mara Ferrandi
Patrizia Ferrari
Maria Pia Zappavigna
Leonardo Banfi
Giuseppe Giacalone
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Application granted granted Critical
Publication of DK2032593T3 publication Critical patent/DK2032593T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
    • C07J73/005—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by nitrogen as hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/004—Expansion of ring B by one atom, e.g. B homo steroids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
    • C07J73/003—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by oxygen as hetero atom

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
DK07729767.9T 2006-06-23 2007-05-31 Aminoderivater af B-homoandrostaner og B-heteroandrostaner DK2032593T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06116001 2006-06-23
PCT/EP2007/055366 WO2007147713A1 (en) 2006-06-23 2007-05-31 Amino derivatives of b-homoandrostanes and b-heteroandrostanes

Publications (1)

Publication Number Publication Date
DK2032593T3 true DK2032593T3 (da) 2011-05-16

Family

ID=37603055

Family Applications (1)

Application Number Title Priority Date Filing Date
DK07729767.9T DK2032593T3 (da) 2006-06-23 2007-05-31 Aminoderivater af B-homoandrostaner og B-heteroandrostaner

Country Status (21)

Country Link
US (1) US8022203B2 (da)
EP (1) EP2032593B1 (da)
JP (1) JP4664433B2 (da)
KR (1) KR101446166B1 (da)
CN (1) CN101479291B (da)
AR (1) AR061561A1 (da)
AT (1) ATE497504T1 (da)
AU (1) AU2007263117B2 (da)
BR (1) BRPI0713439A2 (da)
CA (1) CA2654354C (da)
CY (1) CY1112012T1 (da)
DE (1) DE602007012348D1 (da)
DK (1) DK2032593T3 (da)
EA (1) EA014333B1 (da)
ES (1) ES2359544T3 (da)
HK (1) HK1134097A1 (da)
MX (1) MX2008016425A (da)
PL (1) PL2032593T3 (da)
SI (1) SI2032593T1 (da)
TW (1) TWI372762B (da)
WO (1) WO2007147713A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008150470A1 (en) 2007-05-31 2008-12-11 Shionogi & Co., Ltd. Oxyimino compounds and the use thereof
CN101983187A (zh) * 2008-04-02 2011-03-02 株式会社钟化 (s)-3-(1-氰基-1，1-二苯基甲基)吡咯烷的制备方法
EP2346820B1 (en) 2008-06-11 2013-02-13 Shionogi & Co., Ltd. Oxycarbamoyl compounds and the use thereof
HUE027408T2 (en) * 2009-03-23 2016-10-28 Sigma Tau Ind Farmaceuti Proteinuria, 5ß, 14β-androstane derivatives for the treatment of glomerulosclerosis and renal failure
GB201104199D0 (en) 2011-03-11 2011-04-27 Syngenta Participations Ag Plant growth regulator compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2806029A (en) * 1956-07-16 1957-09-10 Searle & Co 3-oxygenated 12a-aza-c-homopregnane-12, 20-diones and congeners
US3136584A (en) * 1963-01-25 1964-06-09 Whitlock Associates Inc Bulk material hopper unloader
US3328408A (en) * 1964-01-30 1967-06-27 Smith 6-azaestranes, intermediates and process
DE19633349A1 (de) * 1996-08-19 1998-02-26 Sigma Tau Ind Farmaceuti Neue 6-Hydroxy- und 6-Oxo-androstan-Derivate, die auf das kardiovaskuläre System wirken und pharmazeutische Zusammensetzungen, die diese enthalten
US6825208B2 (en) * 2001-08-20 2004-11-30 Bristol-Myers Squibb Pharma Company Tetrahydroquinoline derivatives as antithrombotic agents
US7053076B2 (en) * 2001-08-29 2006-05-30 Xenoport, Inc. Bile-acid derived compounds for enhancing oral absorption and systemic bioavailability of drugs
AU2005258280B2 (en) * 2004-06-24 2009-12-10 Wisconsin Alumni Research Foundation Neoglycorandomization and digitoxin analogs

Also Published As

Publication number Publication date
WO2007147713A1 (en) 2007-12-27
JP2009541410A (ja) 2009-11-26
JP4664433B2 (ja) 2011-04-06
EA014333B1 (ru) 2010-10-29
HK1134097A1 (da) 2010-04-16
CN101479291A (zh) 2009-07-08
AU2007263117A1 (en) 2007-12-27
ES2359544T3 (es) 2011-05-24
AU2007263117B2 (en) 2012-05-24
PL2032593T3 (pl) 2011-05-31
MX2008016425A (es) 2009-01-21
AU2007263117A2 (en) 2009-03-12
CN101479291B (zh) 2012-09-19
DE602007012348D1 (de) 2011-03-17
US20090209506A1 (en) 2009-08-20
KR20090023730A (ko) 2009-03-05
EA200970046A1 (ru) 2009-06-30
CA2654354A1 (en) 2007-12-27
TW200817427A (en) 2008-04-16
US8022203B2 (en) 2011-09-20
EP2032593B1 (en) 2011-02-02
TWI372762B (en) 2012-09-21
EP2032593A1 (en) 2009-03-11
AR061561A1 (es) 2008-09-03
KR101446166B1 (ko) 2014-10-01
SI2032593T1 (sl) 2011-05-31
CY1112012T1 (el) 2015-11-04
BRPI0713439A2 (pt) 2012-03-06
CA2654354C (en) 2014-12-23
ATE497504T1 (de) 2011-02-15

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