DE602007012348D1 - Aminoderivate von b-homoandrostanen und b-heteroandrostanen - Google Patents

Aminoderivate von b-homoandrostanen und b-heteroandrostanen

Info

Publication number
DE602007012348D1
DE602007012348D1 DE602007012348T DE602007012348T DE602007012348D1 DE 602007012348 D1 DE602007012348 D1 DE 602007012348D1 DE 602007012348 T DE602007012348 T DE 602007012348T DE 602007012348 T DE602007012348 T DE 602007012348T DE 602007012348 D1 DE602007012348 D1 DE 602007012348D1
Authority
DE
Germany
Prior art keywords
homoandrostanes
heteroandrostanes
amino derivatives
derivatives
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602007012348T
Other languages
English (en)
Inventor
Alberto Cerri
Barbara Moro
Maco Torri
Giulio Carzana
Giuseppe Bianchi
Mara Ferrandi
Patrizia Ferrari
Maria Pia Zappavigna
Leonardo Banfi
Giuseppe Giacalone
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sigma Tau Industrie Farmaceutiche Riunite SpA
Original Assignee
Sigma Tau Industrie Farmaceutiche Riunite SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Industrie Farmaceutiche Riunite SpA filed Critical Sigma Tau Industrie Farmaceutiche Riunite SpA
Publication of DE602007012348D1 publication Critical patent/DE602007012348D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
    • C07J73/005—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by nitrogen as hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/004—Expansion of ring B by one atom, e.g. B homo steroids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
    • C07J73/003—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by oxygen as hetero atom

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
DE602007012348T 2006-06-23 2007-05-31 Aminoderivate von b-homoandrostanen und b-heteroandrostanen Active DE602007012348D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06116001 2006-06-23
PCT/EP2007/055366 WO2007147713A1 (en) 2006-06-23 2007-05-31 Amino derivatives of b-homoandrostanes and b-heteroandrostanes

Publications (1)

Publication Number Publication Date
DE602007012348D1 true DE602007012348D1 (de) 2011-03-17

Family

ID=37603055

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602007012348T Active DE602007012348D1 (de) 2006-06-23 2007-05-31 Aminoderivate von b-homoandrostanen und b-heteroandrostanen

Country Status (21)

Country Link
US (1) US8022203B2 (de)
EP (1) EP2032593B1 (de)
JP (1) JP4664433B2 (de)
KR (1) KR101446166B1 (de)
CN (1) CN101479291B (de)
AR (1) AR061561A1 (de)
AT (1) ATE497504T1 (de)
AU (1) AU2007263117B2 (de)
BR (1) BRPI0713439A2 (de)
CA (1) CA2654354C (de)
CY (1) CY1112012T1 (de)
DE (1) DE602007012348D1 (de)
DK (1) DK2032593T3 (de)
EA (1) EA014333B1 (de)
ES (1) ES2359544T3 (de)
HK (1) HK1134097A1 (de)
MX (1) MX2008016425A (de)
PL (1) PL2032593T3 (de)
SI (1) SI2032593T1 (de)
TW (1) TWI372762B (de)
WO (1) WO2007147713A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008150470A1 (en) * 2007-05-31 2008-12-11 Shionogi & Co., Ltd. Oxyimino compounds and the use thereof
JP5450387B2 (ja) * 2008-04-02 2014-03-26 株式会社カネカ （ｓ）−３−（１−シアノ−１，１−ジフェニルメチル）−ピロリジンの製造法
US8518934B2 (en) 2008-06-11 2013-08-27 Shonogi & Co., Ltd. Oxycarbamoyl compounds and the use thereof
NZ594412A (en) * 2009-03-23 2013-10-25 Sigma Tau Ind Farmaceuti 5-beta, 14-beta-androstane derivatives useful for the treatment of proteinuria, glomerulosclerosis and renal failure
GB201104199D0 (en) 2011-03-11 2011-04-27 Syngenta Participations Ag Plant growth regulator compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2806029A (en) * 1956-07-16 1957-09-10 Searle & Co 3-oxygenated 12a-aza-c-homopregnane-12, 20-diones and congeners
US3136584A (en) * 1963-01-25 1964-06-09 Whitlock Associates Inc Bulk material hopper unloader
US3328408A (en) * 1964-01-30 1967-06-27 Smith 6-azaestranes, intermediates and process
DE19633349A1 (de) * 1996-08-19 1998-02-26 Sigma Tau Ind Farmaceuti Neue 6-Hydroxy- und 6-Oxo-androstan-Derivate, die auf das kardiovaskuläre System wirken und pharmazeutische Zusammensetzungen, die diese enthalten
WO2003015715A2 (en) * 2001-08-20 2003-02-27 Bristol-Myers Squibb Company Tetrahydroquinoline derivatives as antithrombotic agents
US7053076B2 (en) * 2001-08-29 2006-05-30 Xenoport, Inc. Bile-acid derived compounds for enhancing oral absorption and systemic bioavailability of drugs
WO2006002381A1 (en) * 2004-06-24 2006-01-05 Wisconsin Alumni Research Foundation Neoglycorandomization and digitoxin analogs

Also Published As

Publication number Publication date
CA2654354C (en) 2014-12-23
ATE497504T1 (de) 2011-02-15
AU2007263117B2 (en) 2012-05-24
AU2007263117A2 (en) 2009-03-12
CA2654354A1 (en) 2007-12-27
BRPI0713439A2 (pt) 2012-03-06
AU2007263117A1 (en) 2007-12-27
KR101446166B1 (ko) 2014-10-01
JP4664433B2 (ja) 2011-04-06
JP2009541410A (ja) 2009-11-26
MX2008016425A (es) 2009-01-21
TW200817427A (en) 2008-04-16
AR061561A1 (es) 2008-09-03
CY1112012T1 (el) 2015-11-04
TWI372762B (en) 2012-09-21
EA200970046A1 (ru) 2009-06-30
DK2032593T3 (da) 2011-05-16
HK1134097A1 (de) 2010-04-16
EP2032593B1 (de) 2011-02-02
KR20090023730A (ko) 2009-03-05
EA014333B1 (ru) 2010-10-29
WO2007147713A1 (en) 2007-12-27
EP2032593A1 (de) 2009-03-11
ES2359544T3 (es) 2011-05-24
PL2032593T3 (pl) 2011-05-31
SI2032593T1 (sl) 2011-05-31
US20090209506A1 (en) 2009-08-20
CN101479291B (zh) 2012-09-19
US8022203B2 (en) 2011-09-20
CN101479291A (zh) 2009-07-08

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