DK201600669A1 - Facial mask compositions - Google Patents

Abstract

There is provided a facial mask composition and the preparation method thereof. The facial mask composition comprises, by weight parts, common bletilla tuber 20-40, PORIA ALBA10-30, and the root of redrooted salvia25-40. The beneficial effects of the present invention are that the raw materials of the traditional Chinese medicine may interact with each other and play a synergistic effect, facial blood circulation can be accelerated and wastes and poison gases can be absorbed.

Description

<¹θ> DANMARK (1°) DK 2016 00669 A1 (51)

Patent- og

Varemærkestyrelsen <¹²> PATENTANSØGNING lnt.CI.: A 61 K 8/02 (2006.01)

A 61 K 36/537 (2006.01)

A 61 Q 19/02 (2006.01) A 61 K 36/898 (2006.01)

A 61 K 36/076 (2006.01) A 61 Q 19/00 (2006.01) (21) Ansøgningsnummer: PA 2016 00669 (22) Indleveringsdato: 2016-10-31 (24) Løbedag: 2016-10-31 (41) Aim. tilgængelig: 2018-05-01 (71) Ansøger: Langear Technology Co. Ltd, Room 0684, Building 24, No. 68, Beiqing Road, Haidian district Beijing, Kina (72) Opfinder: Lanping Liu, Room 0684, Building 24, No. 68, Beiqing Road, Haidian district, Beijing, Kina (74) Fuldmægtig: NORDIC PATENT SERVICE A/S, Bredgade 30,1260 København K, Danmark (54) Benævnelse: Facial mask compositions (56) Fremdragne publikationer:

CN 101313998 A CN 104740321 A CN 103751635 A CN 1544036 A (57) Sammendrag:

There is provided a facial mask composition and the preparation method thereof. The facial mask composition comprises, by weight parts, common bletilla tuber 20-40, PORI A ALBA10-30, and the root of redrooted salvia25-40. The beneficial effects of the present invention are that the raw materials of the traditional Chinese medicine may interact with each other and play a synergistic effect, facial blood circulation can be accelerated and wastes and poison gases can be absorbed.

DK 2016 00669 A1

DK 2016 00669 A1

Facial mask compositions

Technical field

The present invention relates to skin caring field, and particularly, relates to facial mask field.

Background

Face is more easily exposed to the ambient environment compared to other body parts, and thus more frequently suffers from the impacts caused io by wind, sunburn, electromagnetic radiation, dirt and so on. Due to various skin properties of the different humans, some facial problems may occur and those people involved therein may feel embarrassed or uncomfortable. More seriously, these problems may negatively affect people’s job, marriage, etc.

Facial mask is very popular in relieving or eliminating the facial problems. However, most facial masks contain heavy metal or phosphor powder components, which may damage people’s skin if these facial masks are used for long time.

Therefore, it is necessary to develop facial masks with nature and safe components to reduce the hurts to skin while being suitable for long-term use.

DK 2016 00669 A1

Summary of the Invention

The purpose of the invention is to provide a facial mask which is safe and effective for facial caring.

According to one aspect of the invention, there is provided a facial 5 mask, comprising by weight parts, common bletilla tuber 20-40, PORIA

ALBA10-30, and the root of red-rooted salvia 25-40.

The beneficial effects of the present invention are that the raw materials of the traditional Chinese medicine may interact with each other and play a synergistic effect, facial blood circulation can be accelerated io and wastes and poison gases can be absorbed.

The traditional Chinese medicine facial mask facilitates nutritional and effective substances to penetrate into a deep layer of skin, and further plays a role in moisture retention, skin moistening, whitening, freckle dispelling, wrinkle resistance, anti-aging, anti-inflammation, toxin elimination and anti-acne.

Further, the various ingredients in the facial masks provided by the present invention may have interactions which results in long quality guarantee period.

Finally, the facial masks provided by the present invention contain 20 only nature plants and does not include any chemical components. Thus, the present invention is healthy to people’s skin and has few hurts thereto.

DK 2016 00669 A1

Embodiments of the invention

The following examples further describe and demonstrate embodiments within the scope of the present invention. The examples are given solely for the purpose of illustration and are not to be construed as limitations of the present invention, as many variations thereof are possible without departing from the spirit and scope of the invention.

According to one aspect of the invention, there is provided a facial mask, comprising by weight parts, common bletilla tuber 20-40, PORIA

ALBA10-30, and the root of red-rooted salvia 25-40. io According to a first embodiment of the present invention, the facial mask comprises, by weight parts, common bletilla tuber 20, PORIA

ALBA10, and the root of red-rooted salvia 25.

According to a second embodiment of the present invention, the facial mask comprises, by weight parts, common bletilla tuber 40, PORIA ALBA is 30, and the root of red-rooted salvia 40.

According to a third embodiment of the present invention, the facial mask comprises, by weight parts, common bletilla tuber 20, PORIA

ALB A3 0, and the root of red-rooted salvia25.

According to a fourth embodiment of the present invention, the facial 20 mask comprises, by weight parts, common bletilla tuber 40, PORIA

ALBA10, and the root of red-rooted salvia 40.

According to a fifth embodiment of the present invention, the facial

DK 2016 00669 A1 mask comprises, by weight parts, common bletilla tuber 30, PORIA ALBA

20, and the root of red-rooted salvia 33.

According to a sixth embodiment of the present invention, the facial mask comprises, by weight parts, common bletilla tuber 20, PORIA ALBA

20, and the root of red-rooted salvia 25.

According to a seventh embodiment of the present invention, the facial mask comprises, by weight parts, common bletilla tuber 40, PORIA

ALBA 20, and the root of red-rooted salvia 40.

According to an eighth embodiment of the present invention, the io facial mask comprises, by weight parts, common bletilla tuber 30, PORIA

ALBA10, and the root of red-rooted salvia 33.

According to a ninth embodiment of the present invention, the facial mask comprises, by weight parts, common bletilla tuber 30, PORIA ALBA

30, and the root of red-rooted salvia 33.

is According to a tenth embodiment of the present invention, the facial mask comprises, by weight parts, common bletilla tuber 25, PORIA

ALBA15, and the root of red-rooted salvia 30.

According to a eleventh embodiment of the present invention, the facial mask comprises, by weight parts, common bletilla tuber 35, PORIA 20 ALBA 25, and the root of red-rooted salvia 35.

According to a twelfth embodiment of the present invention, the facial mask comprises, by weight parts, common bletilla tuber 33, PORIA ALBA

DK 2016 00669 A1

27, and the root of red-rooted salvia 33.

According to a thirteenth embodiment of the present invention, the facial mask comprises, by weight parts, common bletilla tuber 24, PORIA

ALBA 26, and the root of red-rooted salvia 30.

It is worth mentioning that the term “weight part” means the ratio between the respective components or ingredients but does not mean the percentage over the whole weight.

METHOD OF PREPARATION io The above described material or ingredients are commercial available in market or can be obtained by conventional processing method, for example, these materials can be obtained by drying and crushing the material into powers whose average particle size ranges from 20-30 mesh.

The preparation of the traditional Chinese medicine extract includes is the following operations.

Mixing and grinding the respective ingredients to powders, using ethanol as a solvent to implement supercritical carbon dioxide extraction to the powders, under 60°C, 30Mpa for 0.5 hour. In particular, the amount of the ethanol is 2ml per gram of said powder, the analytical pressure is lOMPa and the analytical temperature is 20 °C.

Performing reduced pressure concentration and recovery of the ethanol to obtain ethanol extract concentrate.

DK 2016 00669 A1

Twice boiling the residual after the supercritical carbon dioxide extraction is implemented, wherein firstly boiling the residual with 8-10 times of water for 30-50 minutes; and secondly boiling the residual with ΟΙ 2 times of water for 80-90 minutes.

Filtering the boiled liquid and combining the filtered liquid, which is then concentrated to liquid with density between 1.3-1.5 at 50 °C.

Drying the liquid with density between 1.3-1.5 to obtain extractum.

Enriching the extractum with macroporous adsorptive resins, in particular, the extractum is diluted with a certain amount of water, mixed io with same volume of D-101 macroporous adsorptive resins and loaded onto D-101 or AB-8 type and other non-polar, weak-polar or middle-polar of macroporous adsorptive resins. The loading volume is calculated with the ration of 1:3 between the production volume to the resins. After 15minitue’s static adsorption, elution is performed using ten times of volume is of ethanol with different densities and 60%-70% of Ethanol elution solution is collected to obtain brown powder.

Further, the powder is mixed with the brown oil-like mucus obtained through supercritical carbon dioxide extraction, and thereby to obtain the transitional Chinese medicine extract.

A Pigmentation model induced by UVB is employed and the traditional Chinese medicine is administrated as below.

Three separated regions (2cmx2cm) on the back of each guinea pig are selected and the long hair of the back of each guinea pig is cut with

DK 2016 00669 A1 scissors and the short hair is cleared off with electrical shaving machine. Then, said regions are irradiated with SS-04B type of Phototherapy device equipped with UVB lighting source with spectrum peak between 310315nm. Said regions are irradiated with amount of 200mJ/cm² for 20 minutes every day, and the irradiation lasts for 2 weeks to obtain the accumulated irradiation amount of 2800mJ/ cm². The medicine is administrated two hours after the irradiation is completed and the medicine administration lasts for two weeks after the irradiation is finished. Then, the face tissue is taken for pathological examination.

io The samples are divided into three groups for observing the number of cells containing melanin and DOPA positive cells.

Group 1: reference group comprising back skins of normal guinea pigs which are not irradiated by UVB;

Group 2: a group comprising back skins of guinea pigs which are is irradiated by UVB but not coated with the traditional Chinese medicine of the present invention;

Group 3: a group comprising back skins of guinea pigs which are coated with the traditional Chinese medicine of embodiments 1-13 after

UVB irradiation, wherein the concentrations are 0.5 and 1 mg/ml, respectively.

Staining process ) HE staining: a skin sample (2cmx2cm) of the back of the guinea pig is HE-stained with conventional paraffin section.

DK 2016 00669 A1 ) Schmor staining:

a. The section is rinsed with water;

b. The section is then processed for ten minutes with the mixture of 40ml of FeCU solution with concentration of 0.04mol/L, 6ml of potassium ferricyanide solution with concentration of 0.04mol/L and 6ml of distilled water;

c. The section is then rinsed with flowing water.

Result: melanin cells are stained into brown, black particles.

3) Imokawa staining io a. A skin sample (2cmx2cm) is taken from the back of a guinea pig, rinsed with PBS liquid with concentration of 0.1mol/L (PH6.8) and then incubated with sodium bromide with concentration of lmol/L at 3 7 °C for 5 hours.

b. The cuticle and dermis of the skin is separated, is c. The cuticle is regulated with cooled neutral formalin solution with concentration of 3.33mol/L (10%) for 30 minutes, and then rinsed with PBS solution with concentration of 0. lmol/L (PH6.8) for two times.

d. The cuticle is then stained with PBS solution with concentration of 0.lmol/L for 5 hours.

Result: the melanin cells are stained into black and brown particles.

DK 2016 00669 A1

Light microscope observation

1) The counting of melanin particle cells: Schmorl staining progress, the number of melanin particle cells per mm² of cuticle substrate of each sample is counted with Net eyepiece micrometer single blind method under high magnification lens;

2) The counting of DOPA positive cells: Imokawa staining progress, the number of DOPA positive melanin cells per mm2 of cuticle substrate of each sample is counted with Net eyepiece micrometer single blind method under high magnification lens.

Groups	Counting of melanin particle cells	Counting of DOPA positive melanin cells
Group without irradiation	359.86	161.80
Group with irradiation	489.70	260.96
Embodiment 1	375.78	172.32
Embodiment 2	385.92	185.60
Embodiment 3	384.53	185.33
Embodiment 4	387.78	184.61
Embodiment 5	371.27	171.08
Embodiment 6	384.25	183.93
Embodiment 7	383.81	183.39
Embodiment 8	382.57	185.00
Embodiment 9	387.60	183.42
Embodiment 10	386.22	187.61
Embodiment 11	374.30	175.10
Embodiment 12	378.13	177.35
Embodiment 13	385.36	185.86

io Table 1

Table 1 shows the average numbers of melanin particle cells and

DOPA positive melanin cells with respect to group without irradiation, group without irradiation and groups applied with the facial mask

DK 2016 00669 A1 according to embodiments 1-13 of the present invention.

Compared with the reference group, the second group which is exposed under UVB irradiation has much higher number of melanin particle cells and DOPA positive melanin cells.

After applied with the embodiments 1-13 of the present invention, the numbers of melanin particle cells and DOPA positive melanin cells of the cuticle has significantly reduced to levels which are quite close to the reference group. Obviously, the present invention shows good effects in skin whitening and chloasma removing.

io In particular, embodiment 5 shows the best effect among the embodiments 1-13 in reducing the numbers of melanin particle cells and DOPA positive melanin cells, and sometimes this embodiment reaches a very close level to the reference group.

Further, embodiments 1, 11 and 12 also illustrate relatively better performances compared with other embodiment except embodiment 1.

The facial mask composition of the present invention is suitable for topical application on human body skin, particularly facial skin. The use of the present invention provides skin conditioning benefits such as smoothness, softness, and moisturized feel to the skin due to the deposition and penetration of various components.

The benefit of the present invention is provided by application of the present mask composition in view of the specific benefit agents such as io

DK 2016 00669 A1 chronic whitening agents and skin benefit agents included in the emulsified liquid composition. The mask composition of the present invention is particularly advantageous in delivering nutritious components and other benefit agents into the skin.

Compared to when the liquid composition is applied to the skin without the use of the insoluble substrate, the use of the mask composition of the present invention, with the insoluble substrate as a delivery means over a lengthy period, is believed to provide better distribution and deposition of such agents, and better penetration of those agents which are io percutaneously deliverable.

Further, when an insoluble substrate having low air permeability is used, more effective penetration of the skin benefit agents into the skin is expected. The mask composition of the present invention is also believed to provide emotional benefits to the user upon use, such as refreshing feel, and relaxation feel.

In one preferred embodiment, the mask composition is used to treat the facial skin by the steps of: (a) applying the mask composition to the majority of the area of the facial skin; (b) allowing the mask composition to stand on the facial skin for a period of time no longer than until any portion of the mask composition is dried; (c) removing the mask composition from the facial skin; and (d) removing the remainder liquid composition left on the facial skin.

DK 2016 00669 A1

The mask composition is soaked with an aqueous liquid composition, thus the mask fits to the facial skin by gently placing on the skin. For better fit and even distribution of the nutritious components and other skin benefit agents, the mask is pressed to the facial skin using finger tips.

DK 2016 00669 A1

Claims (3)

1. Claims

   1. A facial mask composition, comprising by weight parts, common bletilla tuber 20-40, PORIA ALBA10-30, and the root of red-rooted salvia25-40.
2. 2. The facial mask composition according to Claim 1, wherein the facial mask composition comprises, by weight parts, common bletilla tuber 20, PORIA ALBA10, and the root of red-rooted salvia25.

   io 3. The facial mask composition according to Claim 1, wherein the facial mask composition comprises, by weight parts, common bletilla tuber 30, PORIA ALBA 20, and the root of red-rooted salvia 33.

   4. The facial mask composition according to Claim 1, wherein the

   15 facial mask composition comprises, by weight parts, common bletilla tuber

   35, PORIA ALBA 25, and the root of red-rooted salvia 35.

   5. The facial mask composition according to Claim 1, wherein the facial mask composition comprises, by weight parts, common bletilla

   20 tuber 33, PORIA ALBA 27, and the root of red-rooted salvia 33.

   IMmsH Fäto? Asm Öma

   SEARCH REPORT - PATENT Application No. PA 2016 00669 1. 1 1 Certain claims were found unsearchable (See Box No. I). 2. 1 1 Unity of invention is lacking prior to search (See Box No. II). A. CLASSIFICATION OF SUBJECT MATTER A 61 K 8/02 (2006.01); A 61 Q 19/02 (2006.01); A 61 K 36/076 (2006.01); A 61 K 36/537 (2006.01); A 61 K 36/898 (2006.01); A 61 Q 19/00 (2006.01) According to International Patent Classification (IPC) or to both national classification and IPC B. FIELDS SEARCHED PCT-minimum documentation searched (classification system followed by classification symbols) Documentation searched other than PCT-minimum documentation Electronic database consulted during the search (name of database and, where practicable, search terms used) EPODOC, WPI, TCM, FULL TEXT: ENGLISH, GERMAN, FRENCH C. DOCUMENTS CONSIDERED TO BE RELEVANT Category* Citation of document, with indication, where appropriate, of the relevant passages Relevant for claim No. X; A CN 101313998 A (LI, Y.) 3 December 2008 Whole document, in particular abstract 1; 2-5 X; A CN 104740321 A (TEACHING HOSPITAL CHENGDU UNIV TRADITIONAL CHINESE MEDICINE) 1 July 2015 Whole document, in particular abstract 1; 2-5 A CN 103751635 A (QINGDAO HENGBO INSTR CO LTD) 30 April 2014 Whole document, in particular abstract 1-5 A CN 1544036 A (LIU, X.) 10 November 2004 Whole document 1-5 1 1 Further documents are listed in the continuation of Box C. * Special categories of cited documents: A Document defining the general state of the art which is not considered to be of particular relevance. D Document cited in the application. E Earlier application or patent but published on or after the filing date. P Document published prior to the filing date but later than the priority date claimed. T Document not in conflict with the application but cited to understand the principle or theory underlying the invention. X Document of particular relevance; the claimed invention cannot be considered novel or cannot be considered to involve an inventive step when the document is taken alone. Y Document of particular relevance; the claimed invention cannot be considered to involve an inventive step when the document is combined with one or more other such documents, such combination being obvious to a person skilled in the art. L Document which may throw doubt on priority claim(s) or which is cited to establish the publication date of another citation or other special reason (as specified). O Document referring to an oral disclosure, use, exhibition or other means. Document member of the same patent family. Danish Patent and Trademark Office Helgeshøj Allé 81 DK-2630 Taastrun Date of completion of the search report 17 January 2018 Denmark Authorized officer Telephone No. +45 4350 8000 Facsimile No. +45 4350 8001 E-ri Maria Sol Telephone No. +45 4350 8588

   Search Report

   SEARCH REPORT - PATENT Application No. PA 2016 00669 C (Continuation). DOCUMENTS CONSIDERED TO BE RELEVANT Category* Citation of document, with indication, where appropriate, of the relevant passages Relevant for claim No.

   Search Report

   SEARCH REPORT - PATENT Application No. PA 2016 00669 Box No. I Observations where certain claims were found unsearchable

   This search report has not been established in respect of certain claims for the following reasons: !·□ Claims Nos.:

   because they relate io subject matter not required to be searched, namely:

   2. I I Claims Nos.:

   because they relate to parts of the patent application that do not comply with the prescribed requirements to such an extent that no meaningful search can be carried out, specifically:
3. 3. I I Claims Nos.: because of other matters.

   Box No. II Observations where unity of invention is lacking prior to the search

   The Danish Patent and Trademark Office found multiple inventions in this patent application, as follows:

   Search Report

   SEARCH REPORT - PATENT Application No. PA 2016 00669 SUPPLEMENTAL BOX Continuation of Box [.]

   Search Report