DK200586A - Anvendelse af pyridinonforbindelser med antithrombotisk virkning i laegemidler - Google Patents

Anvendelse af pyridinonforbindelser med antithrombotisk virkning i laegemidler Download PDF

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Publication number
DK200586A
DK200586A DK200586A DK200586A DK200586A DK 200586 A DK200586 A DK 200586A DK 200586 A DK200586 A DK 200586A DK 200586 A DK200586 A DK 200586A DK 200586 A DK200586 A DK 200586A
Authority
DK
Denmark
Prior art keywords
antithromobotic
application
effect
medicinal products
pyridinone compounds
Prior art date
Application number
DK200586A
Other languages
English (en)
Other versions
DK200586D0 (da
Inventor
Juergen Daemmgen
Helmut Ballhause
Walter Haarman
Joachim Heider
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of DK200586D0 publication Critical patent/DK200586D0/da
Publication of DK200586A publication Critical patent/DK200586A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C07D239/91—Oxygen atoms with aryl or aralkyl radicals attached in position 2 or 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Description

alkylengruppe, der er substitueret i yderpositionen med en methoxyphenyl-, dimethoxyphenyl eller en methylphe-noxygruppe; og R3 betegner et hydrogenatom eller en methoxygruppe, deres antipoder samt fysiologisk acceptable syreadditionssalte med uorganiske eller organiske syrer til behandling af og profylakse for thrombo-emboliske sygdomme til profylakse for arteriosklerose og til metastaseprofylakse .
DK200586A 1985-05-03 1986-05-01 Anvendelse af pyridinonforbindelser med antithrombotisk virkning i laegemidler DK200586A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19853515882 DE3515882A1 (de) 1985-05-03 1985-05-03 Arzneimittel, enthaltend pyridinone mit antithrombotischen wirkungen und verfahren zu ihrer herstellung
DE3515882 1985-05-03

Publications (2)

Publication Number Publication Date
DK200586D0 DK200586D0 (da) 1986-05-01
DK200586A true DK200586A (da) 1986-11-04

Family

ID=6269707

Family Applications (1)

Application Number Title Priority Date Filing Date
DK200586A DK200586A (da) 1985-05-03 1986-05-01 Anvendelse af pyridinonforbindelser med antithrombotisk virkning i laegemidler

Country Status (6)

Country Link
EP (1) EP0210342A2 (da)
JP (1) JPS61254524A (da)
AU (1) AU5706486A (da)
DE (1) DE3515882A1 (da)
DK (1) DK200586A (da)
ZA (1) ZA863304B (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3533542B2 (ja) * 1994-03-08 2004-05-31 株式会社大塚製薬工場 ホスホン酸ジエステル誘導体
US6642244B2 (en) 2001-03-16 2003-11-04 Bristol-Myers Squibb Co. Pyrazolopyridopyrimidine inhibitors of cGMP phosphodiesterase
WO2006045010A2 (en) 2004-10-20 2006-04-27 Resverlogix Corp. Stilbenes and chalcones for the prevention and treatment of cardiovascular diseases
EP2118074B1 (en) 2007-02-01 2014-01-22 Resverlogix Corp. Compounds for the prevention and treatment of cardiovascular diseases
CN101531638B (zh) * 2008-03-13 2011-12-28 中国科学院广州生物医药与健康研究院 用作雌激素相关受体调节剂的化合物及其应用
PL2346837T3 (pl) 2008-06-26 2015-07-31 Resverlogix Corp Sposoby wytwarzania pochodnych chinazolinonu
CN101628913B (zh) 2008-07-18 2013-01-23 中国科学院广州生物医药与健康研究院 用作雌激素相关受体调节剂的化合物及其应用
JP5635535B2 (ja) * 2009-01-08 2014-12-03 レスバーロジックス コーポレイション 心血管疾患の予防および治療のための化合物
MX337352B (es) 2009-03-18 2016-02-29 Resverlogix Corp Nuevos agentes anti-inflamatorios.
EP3431086B1 (en) 2009-04-22 2020-06-17 Resverlogix Corp. Novel anti-inflammatory agents
LT2773354T (lt) 2011-11-01 2019-08-12 Resverlogix Corp. Geriamosios greitai atsipalaiduojančios pakeistų chinozolinų vaisto formos
WO2014080290A2 (en) 2012-11-21 2014-05-30 Rvx Therapeutics Inc. Cyclic amines as bromodomain inhibitors
US9765039B2 (en) 2012-11-21 2017-09-19 Zenith Epigenetics Ltd. Biaryl derivatives as bromodomain inhibitors
CA2895905A1 (en) 2012-12-21 2014-06-26 Zenith Epigenetics Corp. Novel heterocyclic compounds as bromodomain inhibitors
CN114984016A (zh) 2015-03-13 2022-09-02 雷斯韦洛吉克斯公司 用于治疗补体相关疾病之组合物及治疗方法

Also Published As

Publication number Publication date
DK200586D0 (da) 1986-05-01
JPS61254524A (ja) 1986-11-12
ZA863304B (en) 1988-01-27
AU5706486A (en) 1986-11-06
DE3515882A1 (de) 1986-11-06
EP0210342A2 (de) 1987-02-04

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