DK406987D0 - Nye bisfosfonsyrederivater, deres fremstilling og brug - Google Patents
Nye bisfosfonsyrederivater, deres fremstilling og brugInfo
- Publication number
- DK406987D0 DK406987D0 DK406987A DK406987A DK406987D0 DK 406987 D0 DK406987 D0 DK 406987D0 DK 406987 A DK406987 A DK 406987A DK 406987 A DK406987 A DK 406987A DK 406987 D0 DK406987 D0 DK 406987D0
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- acid derivatives
- bisphosphonic acid
- new
- new bisphosphonic
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6536—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and sulfur atoms with or without oxygen atoms, as the only ring hetero atoms
- C07F9/6544—Six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6536—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and sulfur atoms with or without oxygen atoms, as the only ring hetero atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB858530603A GB8530603D0 (en) | 1985-12-12 | 1985-12-12 | Chemical compounds |
GB8530603 | 1985-12-12 | ||
PCT/DK1986/000132 WO1987003598A1 (en) | 1985-12-12 | 1986-12-10 | Novel bisphosphonic derivatives, a method for their production and a pharmaceutical composition |
DK8600132 | 1986-12-10 |
Publications (3)
Publication Number | Publication Date |
---|---|
DK406987D0 true DK406987D0 (da) | 1987-08-05 |
DK406987A DK406987A (da) | 1987-08-05 |
DK169678B1 DK169678B1 (da) | 1995-01-09 |
Family
ID=10589647
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK406987A DK169678B1 (da) | 1985-12-12 | 1987-08-05 | Nye bisfosfonsyrederivater, farmaceutisk præparat indeholdende disse, samt deres fremstilling og brug |
Country Status (8)
Country | Link |
---|---|
US (1) | US4870063A (da) |
EP (1) | EP0248854B1 (da) |
JP (1) | JPS63501956A (da) |
CA (1) | CA1287350C (da) |
DE (1) | DE3670639D1 (da) |
DK (1) | DK169678B1 (da) |
GB (1) | GB8530603D0 (da) |
WO (1) | WO1987003598A1 (da) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL86951A (en) * | 1987-07-06 | 1996-07-23 | Procter & Gamble Pharma | Methylene phosphonoalkylphosphinates and pharmaceutical preparations containing them |
EP0416689B1 (en) * | 1989-09-06 | 1995-11-29 | Merck & Co. Inc. | Acyloxymethyl esters of bisphosphonic acids as bone resorption inhibitors |
US5227506A (en) * | 1989-09-06 | 1993-07-13 | Merck & Co., Inc. | Acyloxymethyl esters of bisphosphonic acids as bone resorption inhibitors |
FI89366C (fi) * | 1990-12-20 | 1993-09-27 | Leiras Oy | Foerfarande foer framstaellning av nya farmakologiskt anvaendbara metylenbisfosfonsyraderivat |
AU642336B2 (en) * | 1991-02-07 | 1993-10-14 | Kaken Pharmaceutical Co., Ltd. | Bisphosphonic acid derivatives, their intermediates and bone resorption inhibitors containing them as active ingredients |
JPH05163150A (ja) * | 1991-05-13 | 1993-06-29 | E R Squibb & Sons Inc | アテローム性動脈硬化症の抑制・治療剤 |
FR2703590B1 (fr) * | 1993-04-05 | 1995-06-30 | Sanofi Elf | Utilisation de derives d'acide bisphosphonique pour la preparation de medicaments destines a favoriser la reparation osseuse . |
US20010007863A1 (en) * | 1998-06-18 | 2001-07-12 | Merck & Co., Inc. | Wet granulation formulation for bisphosphonic acids |
US5616571A (en) * | 1995-06-06 | 1997-04-01 | Merck & Co., Inc. | Bisphosphonates prevent bone loss associated with immunosuppressive therapy |
US6376476B1 (en) * | 1996-12-13 | 2002-04-23 | Zymogenetics Corporation | Isoprenoid pathway inhibitors for stimulating bone growth |
US6416737B1 (en) | 1998-11-19 | 2002-07-09 | Board Of Trustees Of The University Of Arkansas | Increasing bone strength with selected bisphosphonates |
US7041309B2 (en) * | 2002-06-13 | 2006-05-09 | Neuropro Technologies, Inc. | Spinal fusion using an HMG-CoA reductase inhibitor |
WO2005090370A1 (en) | 2004-02-05 | 2005-09-29 | The Regents Of The University Of California | Pharmacologically active agents containing esterified phosphonates and methods for use thereof |
JP2008535862A (ja) | 2005-04-08 | 2008-09-04 | キメリクス,インコーポレイテッド | ポックスウイルス感染の治療のための化合物、組成物および方法 |
US20070003608A1 (en) * | 2005-04-08 | 2007-01-04 | Almond Merrick R | Compounds, compositions and methods for the treatment of viral infections and other medical disorders |
WO2009094190A2 (en) * | 2008-01-25 | 2009-07-30 | Chimerix, Inc. | Methods of treating viral infections |
WO2011011519A1 (en) | 2009-07-21 | 2011-01-27 | Chimerix, Inc. | Compounds, compositions and methods for treating ocular conditions |
JP2013501056A (ja) | 2009-08-03 | 2013-01-10 | キメリクス,インコーポレイテッド | ウイルス感染およびウイルス誘発腫瘍を治療する組成物および方法 |
DK2534150T3 (da) | 2010-02-12 | 2017-06-12 | Chimerix Inc | Fremgangsmåder til behandling af virusinfektion |
US9278135B2 (en) | 2010-04-26 | 2016-03-08 | Chimerix Inc. | Methods of treating retroviral infections and related dosage regimes |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PH9776A (en) * | 1967-12-11 | 1976-03-17 | M Francis | Compositions for inhibiting anomalous deposition and mobilization of calcium phosphate in animal tissue and method of use |
JPS5095227A (da) * | 1973-12-26 | 1975-07-29 | ||
US4311663A (en) * | 1978-08-09 | 1982-01-19 | Petrolite Corporation | α-1,4-Thiazine alkanephosphonic acids as corrosion inhibitors |
US4264768A (en) * | 1978-08-09 | 1981-04-28 | Petrolite Corporation | Di-quaternary ammonium salts of α-1,4-thiazine alkanephosphonic acids |
DE3225469A1 (de) * | 1982-07-05 | 1984-01-05 | Schering AG, 1000 Berlin und 4709 Bergkamen | Diphosphonsaeure-derivate und diese enthaltende pharmazeutische praeparate |
DE3232998A1 (de) * | 1982-09-04 | 1984-03-08 | Henkel KGaA, 4000 Düsseldorf | Diphosphonsaeuren |
-
1985
- 1985-12-12 GB GB858530603A patent/GB8530603D0/en active Pending
-
1986
- 1986-12-10 DE DE8787900075T patent/DE3670639D1/de not_active Expired - Fee Related
- 1986-12-10 WO PCT/DK1986/000132 patent/WO1987003598A1/en active IP Right Grant
- 1986-12-10 EP EP87900075A patent/EP0248854B1/en not_active Expired - Lifetime
- 1986-12-10 US US07/090,980 patent/US4870063A/en not_active Expired - Fee Related
- 1986-12-10 JP JP62500254A patent/JPS63501956A/ja active Pending
- 1986-12-11 CA CA000525118A patent/CA1287350C/en not_active Expired - Fee Related
-
1987
- 1987-08-05 DK DK406987A patent/DK169678B1/da active
Also Published As
Publication number | Publication date |
---|---|
EP0248854A1 (en) | 1987-12-16 |
JPS63501956A (ja) | 1988-08-04 |
DK169678B1 (da) | 1995-01-09 |
GB8530603D0 (en) | 1986-01-22 |
EP0248854B1 (en) | 1990-04-25 |
DE3670639D1 (de) | 1990-05-31 |
CA1287350C (en) | 1991-08-06 |
DK406987A (da) | 1987-08-05 |
WO1987003598A1 (en) | 1987-06-18 |
US4870063A (en) | 1989-09-26 |
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