DK1992369T3 - Fremgangsmåde til fremstilling af et hæmokompatibelt objekt med kompleks konfiguration og genstand derved opnået - Google Patents

Fremgangsmåde til fremstilling af et hæmokompatibelt objekt med kompleks konfiguration og genstand derved opnået Download PDF

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Publication number
DK1992369T3
DK1992369T3 DK08290405.3T DK08290405T DK1992369T3 DK 1992369 T3 DK1992369 T3 DK 1992369T3 DK 08290405 T DK08290405 T DK 08290405T DK 1992369 T3 DK1992369 T3 DK 1992369T3
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DK
Denmark
Prior art keywords
membrane
prosthesis
configuration
hemocompatible
mold
Prior art date
Application number
DK08290405.3T
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English (en)
Inventor
Antoine Capel
Alain Carpentier
Marion Melot
Original Assignee
Carmat
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carmat filed Critical Carmat
Application granted granted Critical
Publication of DK1992369T3 publication Critical patent/DK1992369T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
    • A61F2/2415—Manufacturing methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/31504—Composite [nonstructural laminate]
    • Y10T428/3154—Of fluorinated addition polymer from unsaturated monomers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Transplantation (AREA)
  • Vascular Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Manufacturing & Machinery (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Surgery (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)
  • Artificial Filaments (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)

Claims (8)

1
1. Fremgangsmåde til fremstilling af et hæmokompatibelt objekt (6), i hvilken fremgangsmåde: - en støbeform (7) havende konfigurationen af objektet (6) fremstilles; - en polytetrafluorethylen-membran (1) tilpasses konfigurationen af objektet (6) ved at varme den og påføre den mod støbeformen (7) ved hjælp af en trykforskel påtrykt mellem de to sider af membranen (1); - membranen derved tilpasset afkøles mens den stadig er i støbeformen (7); og - den tilpassede membran fjernes fra støbeformen (7), kendetegnet ved at: - membranen (1) er lavet af et ekspanderet polytetrafluorethylen som ikke forud for tilpasningen til konfigurationen af objektet (6) er blevet termisk stabiliseret, og hvis fibre (3) ikke har nogen foretrukken orientering; og - membranen (1) opvarmes, mens den stadig tilpasses til konfigurationen af objektet (6), op til en temperatur over geleringspunktet af det ekspanderede polytetrafluorethylen.
2. Fremgangsmåde ifølge krav 1, kendetegnet ved at membranen opvarmes med varm luft.
3. Fremgangsmåde ifølge et hvilket som helst af kravene 1 eller 2, kendetegnet ved at temperaturen til hvilken membranen (1) opvarmes er omkring 400 °C.
4. Fremgangsmåde ifølge et af kravene 1 til 3, kendetegnet ved at den opvarmede membran (1) anvendes i støbeformen (7) med et vakuum igennem sidstnævnte.
5. Fremgangsmåde ifølge et af kravene 1 til 4, kendetegnet ved at afkølingen af den tilpassede membran accelereres.
6. Fremgangsmåde ifølge et af de foregående krav, implementeret til fremstilling af et hæmokompatibelt objekt af kompleks konfiguration som skal danne en coating (6) til en implanterbar protese eller protesedel (4) havende 2 konfigurationen, kendetegnet ved at, efter at membranen som er tilpasset til konfigurationen af protesen eller protesedelen er blevet fjernet fra støbeformen (7), limes membranen til protesen eller protesedelen.
7. Fremgangsmåde ifølge krav 6, kendetegnet ved at, til limning af den tilpassede membran til protesen eller protesedelen (4) monteres den tilpassede membran på et oppusteligt redskab (11) af lignende form og, efter den tilpassede membran er blevet bragt i kontakt med protesen eller protesedelen via mindst et lag af klæbemiddel, oppustes redskabet (11) for at komprimere laget og sikre at det har en ensartet tykkelse. B. Fremgangsmåde ifølge et hvilket som helst af kravene 6 eller 7, kendetegnet ved at limningen opnås ved hjælp af en elastomer, såsom en silikone.
9. Fremgangsmåde ifølge et af kravene 1 til 8, kendetegnet ved at det Fremstillede objekt er en hæmokompatibel coating (6) som dækker mindst en af delene af en hjerteprotese.
DK08290405.3T 2007-05-10 2008-04-28 Fremgangsmåde til fremstilling af et hæmokompatibelt objekt med kompleks konfiguration og genstand derved opnået DK1992369T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0703339A FR2915903B1 (fr) 2007-05-10 2007-05-10 Procede pour la realisation d'un objet hemocompatible de configuration complexe et objet ainsi obtenu.

Publications (1)

Publication Number Publication Date
DK1992369T3 true DK1992369T3 (da) 2015-07-20

Family

ID=38849264

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08290405.3T DK1992369T3 (da) 2007-05-10 2008-04-28 Fremgangsmåde til fremstilling af et hæmokompatibelt objekt med kompleks konfiguration og genstand derved opnået

Country Status (14)

Country Link
US (1) US8728264B2 (da)
EP (1) EP1992369B1 (da)
JP (1) JP5427777B2 (da)
KR (1) KR101476160B1 (da)
CN (1) CN101711169A (da)
AU (1) AU2008257275B2 (da)
CA (1) CA2686444C (da)
DK (1) DK1992369T3 (da)
ES (1) ES2542351T3 (da)
FR (1) FR2915903B1 (da)
PL (1) PL1992369T3 (da)
RU (1) RU2430744C2 (da)
WO (1) WO2008145870A2 (da)
ZA (1) ZA200907664B (da)

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US8579964B2 (en) 2010-05-05 2013-11-12 Neovasc Inc. Transcatheter mitral valve prosthesis
US9308087B2 (en) 2011-04-28 2016-04-12 Neovasc Tiara Inc. Sequentially deployed transcatheter mitral valve prosthesis
US9554897B2 (en) 2011-04-28 2017-01-31 Neovasc Tiara Inc. Methods and apparatus for engaging a valve prosthesis with tissue
US9345573B2 (en) 2012-05-30 2016-05-24 Neovasc Tiara Inc. Methods and apparatus for loading a prosthesis onto a delivery system
US9572665B2 (en) 2013-04-04 2017-02-21 Neovasc Tiara Inc. Methods and apparatus for delivering a prosthetic valve to a beating heart
CN108601645B (zh) 2015-12-15 2021-02-26 内奥瓦斯克迪亚拉公司 经中隔递送系统
EP4183372A1 (en) 2016-01-29 2023-05-24 Neovasc Tiara Inc. Prosthetic valve for avoiding obstruction of outflow
EP3541462A4 (en) 2016-11-21 2020-06-17 Neovasc Tiara Inc. METHODS AND SYSTEMS FOR RAPID RETRACTION OF A TRANSCATHETER HEART VALVE DELIVERY SYSTEM
US10856984B2 (en) 2017-08-25 2020-12-08 Neovasc Tiara Inc. Sequentially deployed transcatheter mitral valve prosthesis
AU2019374743B2 (en) 2018-11-08 2022-03-03 Neovasc Tiara Inc. Ventricular deployment of a transcatheter mitral valve prosthesis
EP3911693A4 (en) 2019-01-15 2022-08-24 Palziv Ein Hanaziv Agricultural Cooperative Society Ltd. OPEN CELL EXPANDED POLYMER SHEET CONTINUOUS PROCESS
CA3132873A1 (en) 2019-03-08 2020-09-17 Neovasc Tiara Inc. Retrievable prosthesis delivery system
CN113811265A (zh) 2019-04-01 2021-12-17 内奥瓦斯克迪亚拉公司 能够以可控的方式部署的假体瓣膜
AU2020271896B2 (en) 2019-04-10 2022-10-13 Neovasc Tiara Inc. Prosthetic valve with natural blood flow
WO2020236931A1 (en) 2019-05-20 2020-11-26 Neovasc Tiara Inc. Introducer with hemostasis mechanism
WO2020257643A1 (en) 2019-06-20 2020-12-24 Neovasc Tiara Inc. Low profile prosthetic mitral valve

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Also Published As

Publication number Publication date
KR101476160B1 (ko) 2014-12-24
AU2008257275B2 (en) 2013-09-26
RU2009145704A (ru) 2011-06-20
WO2008145870A8 (fr) 2009-08-06
ZA200907664B (en) 2010-07-28
AU2008257275A1 (en) 2008-12-04
US8728264B2 (en) 2014-05-20
CA2686444C (fr) 2014-07-15
KR20100017723A (ko) 2010-02-16
FR2915903A1 (fr) 2008-11-14
CN101711169A (zh) 2010-05-19
PL1992369T3 (pl) 2015-10-30
US20110244246A1 (en) 2011-10-06
JP5427777B2 (ja) 2014-02-26
RU2430744C2 (ru) 2011-10-10
WO2008145870A3 (fr) 2009-02-19
EP1992369A1 (fr) 2008-11-19
EP1992369B1 (fr) 2015-05-06
JP2010526573A (ja) 2010-08-05
ES2542351T3 (es) 2015-08-04
WO2008145870A2 (fr) 2008-12-04
FR2915903B1 (fr) 2010-06-04
CA2686444A1 (fr) 2008-12-04

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