DK198490D0 - Heterocykliske forbindelser, deres fremstilling og anvendelse - Google Patents

Heterocykliske forbindelser, deres fremstilling og anvendelse

Info

Publication number
DK198490D0
DK198490D0 DK198490A DK198490A DK198490D0 DK 198490 D0 DK198490 D0 DK 198490D0 DK 198490 A DK198490 A DK 198490A DK 198490 A DK198490 A DK 198490A DK 198490 D0 DK198490 D0 DK 198490D0
Authority
DK
Denmark
Prior art keywords
compounds
preparation
heterocyclic compounds
forebrain
hippocampus
Prior art date
Application number
DK198490A
Other languages
Danish (da)
English (en)
Inventor
Per Sauerberg
Preben H Olesen
Charles H Mitch
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Priority to DK198490A priority Critical patent/DK198490D0/da
Publication of DK198490D0 publication Critical patent/DK198490D0/da
Priority to IL99146A priority patent/IL99146A/en
Priority to US07/744,150 priority patent/US5328923A/en
Priority to EP91914368A priority patent/EP0544714B1/en
Priority to NZ239475A priority patent/NZ239475A/xx
Priority to ES91914368T priority patent/ES2079075T3/es
Priority to DK91914368.5T priority patent/DK0544714T3/da
Priority to AU84229/91A priority patent/AU660938B2/en
Priority to JP03513658A priority patent/JP3100159B2/ja
Priority to DE69114848T priority patent/DE69114848T2/de
Priority to ZA916580A priority patent/ZA916580B/xx
Priority to CA002089770A priority patent/CA2089770A1/en
Priority to PCT/DK1991/000235 priority patent/WO1992003431A1/en
Priority to AT91914368T priority patent/ATE130611T1/de
Priority to IE295991A priority patent/IE73873B1/en
Priority to PT98735A priority patent/PT98735B/pt
Priority to NO930600A priority patent/NO302415B1/no
Priority to FI930746A priority patent/FI930746A/fi
Priority to US08/472,350 priority patent/US5591755A/en
Priority to GR950403619T priority patent/GR3018479T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Lubricants (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cephalosporin Compounds (AREA)
DK198490A 1990-08-21 1990-08-21 Heterocykliske forbindelser, deres fremstilling og anvendelse DK198490D0 (da)

Priority Applications (20)

Application Number Priority Date Filing Date Title
DK198490A DK198490D0 (da) 1990-08-21 1990-08-21 Heterocykliske forbindelser, deres fremstilling og anvendelse
IL99146A IL99146A (en) 1990-08-21 1991-08-09 3-(3-substituted 1, 2, 5-thia (or oxa) diazol-4-yl)-1, 2, 5, 6-tetrahydropyridine derivatives, their preparation and pharmaceutical compositions containing them
US07/744,150 US5328923A (en) 1990-08-21 1991-08-13 Heterocyclic compounds and use
AT91914368T ATE130611T1 (de) 1990-08-21 1991-08-20 Heterozyklische verbindungen, ihre herstellung und anwendung.
JP03513658A JP3100159B2 (ja) 1990-08-21 1991-08-20 複素環式化合物及びそれらの調製及び用途
PCT/DK1991/000235 WO1992003431A1 (en) 1990-08-21 1991-08-20 Heterocyclic compounds and their preparation and use
ES91914368T ES2079075T3 (es) 1990-08-21 1991-08-20 Compuestos heterociclicos y su preparacion y uso.
DK91914368.5T DK0544714T3 (da) 1990-08-21 1991-08-20 Heterocycliske forbindelser og fremstilling og anvendelse deraf
AU84229/91A AU660938B2 (en) 1990-08-21 1991-08-20 Thiadiazole/oxadiazole substituted tetrahydropyridines
EP91914368A EP0544714B1 (en) 1990-08-21 1991-08-20 Heterocyclic compounds and their preparation and use
DE69114848T DE69114848T2 (de) 1990-08-21 1991-08-20 Heterozyklische verbindungen, ihre herstellung und anwendung.
ZA916580A ZA916580B (en) 1990-08-21 1991-08-20 Heterocyclic compounds and their preparation and use
CA002089770A CA2089770A1 (en) 1990-08-21 1991-08-20 Heterocyclic compounds and their preparation and use
NZ239475A NZ239475A (en) 1990-08-21 1991-08-20 Thiadiazole and oxadiazole derivatives, preparation and pharmaceutical compositions thereof
PT98735A PT98735B (pt) 1990-08-21 1991-08-21 Processo de preparacao de compostos azaciclicos e de composicoes farmaceuticas que os contem
IE295991A IE73873B1 (en) 1990-08-21 1991-08-21 Heterocyclic compounds and their preparation and use
NO930600A NO302415B1 (no) 1990-08-21 1993-02-19 Analogifremgangsmåte ved fremstilling av heterocykliske forbindelser
FI930746A FI930746A (fi) 1990-08-21 1993-02-19 Heterocykliska foereningar och deras framstaellning och anvaendning
US08/472,350 US5591755A (en) 1990-08-21 1995-06-07 Pyridinyl thiadiazolyl compounds for treating glaucoma
GR950403619T GR3018479T3 (en) 1990-08-21 1995-12-20 Heterocyclic compounds and their preparation and use.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK198490A DK198490D0 (da) 1990-08-21 1990-08-21 Heterocykliske forbindelser, deres fremstilling og anvendelse

Publications (1)

Publication Number Publication Date
DK198490D0 true DK198490D0 (da) 1990-08-21

Family

ID=8109268

Family Applications (2)

Application Number Title Priority Date Filing Date
DK198490A DK198490D0 (da) 1990-08-21 1990-08-21 Heterocykliske forbindelser, deres fremstilling og anvendelse
DK91914368.5T DK0544714T3 (da) 1990-08-21 1991-08-20 Heterocycliske forbindelser og fremstilling og anvendelse deraf

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK91914368.5T DK0544714T3 (da) 1990-08-21 1991-08-20 Heterocycliske forbindelser og fremstilling og anvendelse deraf

Country Status (18)

Country Link
US (2) US5328923A (es)
EP (1) EP0544714B1 (es)
JP (1) JP3100159B2 (es)
AT (1) ATE130611T1 (es)
AU (1) AU660938B2 (es)
CA (1) CA2089770A1 (es)
DE (1) DE69114848T2 (es)
DK (2) DK198490D0 (es)
ES (1) ES2079075T3 (es)
FI (1) FI930746A (es)
GR (1) GR3018479T3 (es)
IE (1) IE73873B1 (es)
IL (1) IL99146A (es)
NO (1) NO302415B1 (es)
NZ (1) NZ239475A (es)
PT (1) PT98735B (es)
WO (1) WO1992003431A1 (es)
ZA (1) ZA916580B (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5043345A (en) * 1989-02-22 1991-08-27 Novo Nordisk A/S Piperidine compounds and their preparation and use
DK198390D0 (da) * 1990-08-21 1990-08-21 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling og anvendelse
US5376668A (en) * 1990-08-21 1994-12-27 Novo Nordisk A/S Heterocyclic compounds
WO1993013083A1 (en) * 1991-12-31 1993-07-08 Fujisawa Pharmaceutical Co., Ltd. Oxadiazole derivatives having acetylcholinesterase-inhibitory and muscarinic agonist activity
JP3126736B2 (ja) * 1993-08-19 2001-01-22 ノボ ノルディスク アクティーゼルスカブ 抗精神病療法
US5753683A (en) * 1993-08-19 1998-05-19 Novo Nordisk A/S Antipsychotic method
US5545638A (en) * 1993-12-21 1996-08-13 Novo Nordisk A/S Method of treating gastrointestinal motility disorders
IL112024A (en) * 1993-12-21 1999-07-14 Novo Nordisk As Pharmaceutical compositions comprising tetrahydropyridine derivatives substituted with oxadiazole or thiadiazole for treating gastrointestinal motility disorders
US5998404A (en) 1994-10-24 1999-12-07 Eli Lilly And Company Heterocyclic compounds and their use
US5605908A (en) * 1994-10-24 1997-02-25 Eli Lilly And Company Heterocyclic compounds and their use
US5821370A (en) * 1994-10-24 1998-10-13 Eli Lilly And Company Heterocyclic compounds and their preparation and use
US5726193A (en) * 1994-10-31 1998-03-10 Eli Lilly And Company Method for treating anxiety
US5488056A (en) * 1994-10-31 1996-01-30 Eli Lilly And Company Method for treating anxiety
US5574028A (en) * 1994-10-31 1996-11-12 Eli Lilly And Company Method for treating anxiety
US5565475A (en) * 1994-11-08 1996-10-15 Muhlhauser; Mark A. Method of treating urinary bladder dysfunctions with 3-tetrahydropyridine derivatives
WO1997040045A1 (en) * 1996-04-24 1997-10-30 Novo Nordisk A/S Heterocyclic compounds and their preparation and use
US6090829A (en) * 1996-08-01 2000-07-18 Eli Lilly And Company Method for treating excessive aggression
US6117890A (en) * 1996-08-01 2000-09-12 Eli Lilly And Company Method for treating bipolar disorder
US6043258A (en) * 1996-08-01 2000-03-28 Eli Lilly And Company Method for treating disruptive behavior disorders with xanomeline
US6034108A (en) * 1997-07-28 2000-03-07 Eli Lilly And Company Method for treating mental retardation
WO1999032486A1 (en) * 1997-12-23 1999-07-01 Alcon Laboratories, Inc. Muscarinic agents and use thereof to treat glaucoma, myopia and various other conditions
EP1983560A2 (en) * 2001-07-10 2008-10-22 Shin-Etsu Handotai Company Limited Method for manufacturing a silicon epitaxial wafer
CN1821243B (zh) * 2005-08-30 2010-12-08 北京大学 取代的吡啶类m1受体激动剂、其制备方法及其用途
US11534434B2 (en) 2019-11-15 2022-12-27 Karuna Therapeutics, Inc. Xanomeline derivatives and methods for treating neurological disorders

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ219646A (en) * 1986-03-27 1990-10-26 Merck Sharp & Dohme Oxadiazole derivatives of azacyclics for treating cns disorders
GB8610432D0 (en) * 1986-04-29 1986-06-04 Akzo Nv Amino-thiazole & oxazole derivatives
IL83275A (en) * 1986-09-08 1994-02-27 Novo Nordisk As Compounds 1,2, 4-Oxadiazolyl Pipridine Transformed, their preparation and pharmaceutical preparations containing them
US5017618A (en) * 1987-03-16 1991-05-21 University Of Florida Labile derivatives of ketone analogs of 3-substituted-1-alkylamino-2-propanols and their use as beta-adrenergic blockers
GB8714789D0 (en) * 1987-06-24 1987-07-29 Lundbeck & Co As H Heterocyclic compounds
GB8717446D0 (en) * 1987-07-23 1987-08-26 Merck Sharp & Dohme Chemical compounds
NZ225999A (en) * 1987-09-10 1992-04-28 Merck Sharp & Dohme Azacyclic- or azabicyclic-substituted thiadiazole derivatives and pharmaceutical compositions
IE63906B1 (en) * 1987-11-13 1995-06-14 Novo Nordisk As Azabicyclic compounds and their preparation and use
EP0322182A3 (en) * 1987-12-22 1992-01-02 Beecham Group Plc Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them
NZ227841A (en) * 1988-02-12 1991-08-27 Merck Sharp & Dohme Heterocyclic compounds with at least two non-condensed five membered rings and pharmaceutical compositions
DK162892C (da) * 1988-07-04 1992-05-11 Novo Nordisk As 1,2,5,6-tetrahydropyridinforbindelser, deres fremstilling og farmaceutiske praeparater indeholdende disse
US5043345A (en) * 1989-02-22 1991-08-27 Novo Nordisk A/S Piperidine compounds and their preparation and use
DK198390D0 (da) * 1990-08-21 1990-08-21 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling og anvendelse

Also Published As

Publication number Publication date
FI930746A0 (fi) 1993-02-19
AU8422991A (en) 1992-03-17
DE69114848T2 (de) 1996-07-18
FI930746A (fi) 1993-03-26
NO302415B1 (no) 1998-03-02
CA2089770A1 (en) 1992-02-22
AU660938B2 (en) 1995-07-13
DK0544714T3 (da) 1996-04-09
DE69114848D1 (de) 1996-01-04
WO1992003431A1 (en) 1992-03-05
EP0544714B1 (en) 1995-11-22
IE73873B1 (en) 1997-07-02
PT98735A (pt) 1992-08-31
IL99146A (en) 1998-01-04
NO930600L (no) 1993-04-16
US5328923A (en) 1994-07-12
US5591755A (en) 1997-01-07
NO930600D0 (no) 1993-02-19
IL99146A0 (en) 1992-07-15
JPH06500541A (ja) 1994-01-20
IE912959A1 (en) 1992-02-26
ZA916580B (en) 1992-05-27
EP0544714A1 (en) 1993-06-09
ATE130611T1 (de) 1995-12-15
ES2079075T3 (es) 1996-01-01
NZ239475A (en) 1994-08-26
GR3018479T3 (en) 1996-03-31
JP3100159B2 (ja) 2000-10-16
PT98735B (pt) 1999-01-29

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Legal Events

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