ZA916580B - Heterocyclic compounds and their preparation and use - Google Patents
Heterocyclic compounds and their preparation and useInfo
- Publication number
- ZA916580B ZA916580B ZA916580A ZA916580A ZA916580B ZA 916580 B ZA916580 B ZA 916580B ZA 916580 A ZA916580 A ZA 916580A ZA 916580 A ZA916580 A ZA 916580A ZA 916580 B ZA916580 B ZA 916580B
- Authority
- ZA
- South Africa
- Prior art keywords
- compounds
- preparation
- heterocyclic compounds
- forebrain
- hippocampus
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Ophthalmology & Optometry (AREA)
- Neurosurgery (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
- Lubricants (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK198490A DK198490D0 (da) | 1990-08-21 | 1990-08-21 | Heterocykliske forbindelser, deres fremstilling og anvendelse |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA916580B true ZA916580B (en) | 1992-05-27 |
Family
ID=8109268
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA916580A ZA916580B (en) | 1990-08-21 | 1991-08-20 | Heterocyclic compounds and their preparation and use |
Country Status (18)
Country | Link |
---|---|
US (2) | US5328923A (es) |
EP (1) | EP0544714B1 (es) |
JP (1) | JP3100159B2 (es) |
AT (1) | ATE130611T1 (es) |
AU (1) | AU660938B2 (es) |
CA (1) | CA2089770A1 (es) |
DE (1) | DE69114848T2 (es) |
DK (2) | DK198490D0 (es) |
ES (1) | ES2079075T3 (es) |
FI (1) | FI930746A (es) |
GR (1) | GR3018479T3 (es) |
IE (1) | IE73873B1 (es) |
IL (1) | IL99146A (es) |
NO (1) | NO302415B1 (es) |
NZ (1) | NZ239475A (es) |
PT (1) | PT98735B (es) |
WO (1) | WO1992003431A1 (es) |
ZA (1) | ZA916580B (es) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5043345A (en) * | 1989-02-22 | 1991-08-27 | Novo Nordisk A/S | Piperidine compounds and their preparation and use |
US5376668A (en) * | 1990-08-21 | 1994-12-27 | Novo Nordisk A/S | Heterocyclic compounds |
DK198390D0 (da) * | 1990-08-21 | 1990-08-21 | Novo Nordisk As | Heterocykliske forbindelser, deres fremstilling og anvendelse |
CA2126976A1 (en) * | 1991-12-31 | 1993-07-08 | Hisashi Takasugi | Oxadiazole derivatives having acetylcholinesterase-inhibitory and muscarinic agonist activity |
US5753683A (en) * | 1993-08-19 | 1998-05-19 | Novo Nordisk A/S | Antipsychotic method |
CZ285030B6 (cs) * | 1993-08-19 | 1999-05-12 | Novo Nordisk A/S | Použití thiadiazolových a oxadiazolových sloučenin pro výrobu farmaceutického prostředku a farmacetický prostředek pro léčení schizofrenie nebo schizofrenních nemocí |
IL112024A (en) * | 1993-12-21 | 1999-07-14 | Novo Nordisk As | Pharmaceutical compositions comprising tetrahydropyridine derivatives substituted with oxadiazole or thiadiazole for treating gastrointestinal motility disorders |
US5545638A (en) * | 1993-12-21 | 1996-08-13 | Novo Nordisk A/S | Method of treating gastrointestinal motility disorders |
US5605908A (en) * | 1994-10-24 | 1997-02-25 | Eli Lilly And Company | Heterocyclic compounds and their use |
US5821370A (en) * | 1994-10-24 | 1998-10-13 | Eli Lilly And Company | Heterocyclic compounds and their preparation and use |
US5998404A (en) * | 1994-10-24 | 1999-12-07 | Eli Lilly And Company | Heterocyclic compounds and their use |
US5574028A (en) * | 1994-10-31 | 1996-11-12 | Eli Lilly And Company | Method for treating anxiety |
US5726193A (en) * | 1994-10-31 | 1998-03-10 | Eli Lilly And Company | Method for treating anxiety |
US5488056A (en) * | 1994-10-31 | 1996-01-30 | Eli Lilly And Company | Method for treating anxiety |
US5565475A (en) * | 1994-11-08 | 1996-10-15 | Muhlhauser; Mark A. | Method of treating urinary bladder dysfunctions with 3-tetrahydropyridine derivatives |
JP2000513712A (ja) * | 1996-04-24 | 2000-10-17 | ノボ ノルディスク アクティーゼルスカブ | 複素環化合物およびその調製およびその使用 |
US6090829A (en) * | 1996-08-01 | 2000-07-18 | Eli Lilly And Company | Method for treating excessive aggression |
US6043258A (en) * | 1996-08-01 | 2000-03-28 | Eli Lilly And Company | Method for treating disruptive behavior disorders with xanomeline |
US6117890A (en) * | 1996-08-01 | 2000-09-12 | Eli Lilly And Company | Method for treating bipolar disorder |
US6034108A (en) * | 1997-07-28 | 2000-03-07 | Eli Lilly And Company | Method for treating mental retardation |
AU2307899A (en) * | 1997-12-23 | 1999-07-12 | Alcon Laboratories, Inc. | Muscarinic agents and use thereof to treat glaucoma, myopia and various other conditions |
EP1406294A4 (en) * | 2001-07-10 | 2007-09-12 | Shinetsu Handotai Kk | PROCESS FOR PRODUCING SILICON WAFER, EPITAXIAL SILICON WAFER, AND EPITAXIAL SILICON WAFER |
CN1821243B (zh) * | 2005-08-30 | 2010-12-08 | 北京大学 | 取代的吡啶类m1受体激动剂、其制备方法及其用途 |
WO2021097427A1 (en) | 2019-11-15 | 2021-05-20 | Karuna Therapeutics, Inc. | Xanomeline derivatives and methods for treating neurological disorders |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ219646A (en) * | 1986-03-27 | 1990-10-26 | Merck Sharp & Dohme | Oxadiazole derivatives of azacyclics for treating cns disorders |
GB8610432D0 (en) * | 1986-04-29 | 1986-06-04 | Akzo Nv | Amino-thiazole & oxazole derivatives |
IL83275A (en) * | 1986-09-08 | 1994-02-27 | Novo Nordisk As | Compounds 1,2, 4-Oxadiazolyl Pipridine Transformed, their preparation and pharmaceutical preparations containing them |
US5017618A (en) * | 1987-03-16 | 1991-05-21 | University Of Florida | Labile derivatives of ketone analogs of 3-substituted-1-alkylamino-2-propanols and their use as beta-adrenergic blockers |
GB8714789D0 (en) * | 1987-06-24 | 1987-07-29 | Lundbeck & Co As H | Heterocyclic compounds |
GB8717446D0 (en) * | 1987-07-23 | 1987-08-26 | Merck Sharp & Dohme | Chemical compounds |
NZ225999A (en) * | 1987-09-10 | 1992-04-28 | Merck Sharp & Dohme | Azacyclic- or azabicyclic-substituted thiadiazole derivatives and pharmaceutical compositions |
IE63906B1 (en) * | 1987-11-13 | 1995-06-14 | Novo Nordisk As | Azabicyclic compounds and their preparation and use |
EP0322182A3 (en) * | 1987-12-22 | 1992-01-02 | Beecham Group Plc | Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them |
NZ227841A (en) * | 1988-02-12 | 1991-08-27 | Merck Sharp & Dohme | Heterocyclic compounds with at least two non-condensed five membered rings and pharmaceutical compositions |
DK162892C (da) * | 1988-07-04 | 1992-05-11 | Novo Nordisk As | 1,2,5,6-tetrahydropyridinforbindelser, deres fremstilling og farmaceutiske praeparater indeholdende disse |
US5043345A (en) * | 1989-02-22 | 1991-08-27 | Novo Nordisk A/S | Piperidine compounds and their preparation and use |
DK198390D0 (da) * | 1990-08-21 | 1990-08-21 | Novo Nordisk As | Heterocykliske forbindelser, deres fremstilling og anvendelse |
-
1990
- 1990-08-21 DK DK198490A patent/DK198490D0/da not_active Application Discontinuation
-
1991
- 1991-08-09 IL IL99146A patent/IL99146A/en not_active IP Right Cessation
- 1991-08-13 US US07/744,150 patent/US5328923A/en not_active Expired - Fee Related
- 1991-08-20 CA CA002089770A patent/CA2089770A1/en not_active Abandoned
- 1991-08-20 AU AU84229/91A patent/AU660938B2/en not_active Ceased
- 1991-08-20 DK DK91914368.5T patent/DK0544714T3/da active
- 1991-08-20 ES ES91914368T patent/ES2079075T3/es not_active Expired - Lifetime
- 1991-08-20 JP JP03513658A patent/JP3100159B2/ja not_active Expired - Fee Related
- 1991-08-20 EP EP91914368A patent/EP0544714B1/en not_active Expired - Lifetime
- 1991-08-20 DE DE69114848T patent/DE69114848T2/de not_active Expired - Fee Related
- 1991-08-20 ZA ZA916580A patent/ZA916580B/xx unknown
- 1991-08-20 AT AT91914368T patent/ATE130611T1/de not_active IP Right Cessation
- 1991-08-20 WO PCT/DK1991/000235 patent/WO1992003431A1/en active IP Right Grant
- 1991-08-20 NZ NZ239475A patent/NZ239475A/xx unknown
- 1991-08-21 IE IE295991A patent/IE73873B1/en not_active IP Right Cessation
- 1991-08-21 PT PT98735A patent/PT98735B/pt not_active IP Right Cessation
-
1993
- 1993-02-19 NO NO930600A patent/NO302415B1/no not_active IP Right Cessation
- 1993-02-19 FI FI930746A patent/FI930746A/fi unknown
-
1995
- 1995-06-07 US US08/472,350 patent/US5591755A/en not_active Expired - Fee Related
- 1995-12-20 GR GR950403619T patent/GR3018479T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
GR3018479T3 (en) | 1996-03-31 |
DE69114848D1 (de) | 1996-01-04 |
US5591755A (en) | 1997-01-07 |
IE912959A1 (en) | 1992-02-26 |
DK198490D0 (da) | 1990-08-21 |
US5328923A (en) | 1994-07-12 |
PT98735A (pt) | 1992-08-31 |
AU8422991A (en) | 1992-03-17 |
JP3100159B2 (ja) | 2000-10-16 |
IL99146A0 (en) | 1992-07-15 |
EP0544714A1 (en) | 1993-06-09 |
NZ239475A (en) | 1994-08-26 |
NO930600L (no) | 1993-04-16 |
DE69114848T2 (de) | 1996-07-18 |
AU660938B2 (en) | 1995-07-13 |
FI930746A (fi) | 1993-03-26 |
IE73873B1 (en) | 1997-07-02 |
FI930746A0 (fi) | 1993-02-19 |
ATE130611T1 (de) | 1995-12-15 |
EP0544714B1 (en) | 1995-11-22 |
PT98735B (pt) | 1999-01-29 |
IL99146A (en) | 1998-01-04 |
WO1992003431A1 (en) | 1992-03-05 |
NO930600D0 (no) | 1993-02-19 |
ES2079075T3 (es) | 1996-01-01 |
NO302415B1 (no) | 1998-03-02 |
CA2089770A1 (en) | 1992-02-22 |
DK0544714T3 (da) | 1996-04-09 |
JPH06500541A (ja) | 1994-01-20 |
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