DK1984008T3 - Krystal af ACE-N- domæne - Google Patents
Krystal af ACE-N- domæneInfo
- Publication number
- DK1984008T3 DK1984008T3 DK07700357.2T DK07700357T DK1984008T3 DK 1984008 T3 DK1984008 T3 DK 1984008T3 DK 07700357 T DK07700357 T DK 07700357T DK 1984008 T3 DK1984008 T3 DK 1984008T3
- Authority
- DK
- Denmark
- Prior art keywords
- ace
- domain
- crystal
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/485—Exopeptidases (3.4.11-3.4.19)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4813—Exopeptidases (3.4.11. to 3.4.19)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/15—Peptidyl-dipeptidases (3.4.15)
- C12Y304/15001—Peptidyl-dipeptidase A (3.4.15.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0600406.3A GB0600406D0 (en) | 2006-01-10 | 2006-01-10 | Crystal |
| PCT/GB2007/000064 WO2007080400A2 (en) | 2006-01-10 | 2007-01-10 | Ace n-domain crystal |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1984008T3 true DK1984008T3 (da) | 2012-10-01 |
Family
ID=35911628
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK07700357.2T DK1984008T3 (da) | 2006-01-10 | 2007-01-10 | Krystal af ACE-N- domæne |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US8796006B2 (da) |
| EP (1) | EP1984008B1 (da) |
| AU (1) | AU2007204226B2 (da) |
| CA (1) | CA2636633C (da) |
| DK (1) | DK1984008T3 (da) |
| GB (1) | GB0600406D0 (da) |
| WO (1) | WO2007080400A2 (da) |
| ZA (1) | ZA200806312B (da) |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3947575A (en) * | 1969-06-30 | 1976-03-30 | E. R. Squibb & Sons, Inc. | Peptides as argiotensin converting enzyme inhibitors |
| US3832337A (en) * | 1970-07-28 | 1974-08-27 | Squibb & Sons Inc | Peptide enzyme inhibitors |
| US3891616A (en) * | 1974-04-17 | 1975-06-24 | Squibb & Sons Inc | Hypotensive {62 -homoaminoacid nonapeptides |
| US4052511A (en) * | 1976-02-13 | 1977-10-04 | E. R. Squibb & Sons, Inc. | Carboxyacylproline derivatives |
| US4053651A (en) * | 1976-05-10 | 1977-10-11 | E. R. Squibb & Sons, Inc. | Compounds and method for alleviating angiotensin related hypertension |
| BR8307525A (pt) | 1982-05-19 | 1984-08-21 | Unilever Nv | Expressao de proteinas semelhantes a pretrotaumatina em leveduras kluyveromyces |
| DE3480411D1 (en) | 1983-07-06 | 1989-12-14 | Gist Brocades Nv | Molecular cloning and expression in industrial microorganism species |
| US4885249A (en) | 1984-12-05 | 1989-12-05 | Allelix, Inc. | Aspergillus niger transformation system |
| DE3650664T2 (de) | 1985-04-15 | 1998-04-16 | Gist Brocades Nv | Verwendung von promotoren von filamentösen pilzen |
| IL83192A (en) | 1986-07-18 | 1992-11-15 | Gist Brocades Nv | Method for the preparation of proteins with factor viii activity by microbial host cells;expression vectors,host cells,antibodies |
| IL87258A (en) | 1987-07-28 | 1994-02-27 | Gist Brocades Nv | SECYMOREVYULK surrogate cells and their use for the expression of polypeptides |
| FR2649412B1 (fr) | 1989-07-05 | 1995-10-20 | Inst Nat Sante Rech Med | Acide nucleique codant pour l'enzyme de conversion de l'angiotensine (eca) testiculaire humaine, et ses applications, notamment pour le depistage in vitro de cette enzyme dans l'organisme |
| KR0166088B1 (ko) | 1990-01-23 | 1999-01-15 | . | 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도 |
| US5376645A (en) | 1990-01-23 | 1994-12-27 | University Of Kansas | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
| JPH03251543A (ja) | 1990-02-26 | 1991-11-11 | Unitika Ltd | アンジオテンシン変換酵素阻害剤 |
| GB9711643D0 (en) | 1997-06-05 | 1997-07-30 | Janssen Pharmaceutica Nv | Glass thermoplastic systems |
| US20040033532A1 (en) * | 2002-08-08 | 2004-02-19 | Ehlers Mario R. W. | Use of three-dimensional crystal structure coordinates to design and synthesize domain-selective inhibitors for angiotensin-converting enzyme (ACE) |
| GB0221169D0 (en) * | 2002-09-12 | 2002-10-23 | Univ Bath | Crystal |
-
2006
- 2006-01-10 GB GBGB0600406.3A patent/GB0600406D0/en not_active Ceased
-
2007
- 2007-01-10 CA CA2636633A patent/CA2636633C/en active Active
- 2007-01-10 DK DK07700357.2T patent/DK1984008T3/da active
- 2007-01-10 US US12/160,562 patent/US8796006B2/en active Active
- 2007-01-10 WO PCT/GB2007/000064 patent/WO2007080400A2/en active Application Filing
- 2007-01-10 ZA ZA200806312A patent/ZA200806312B/xx unknown
- 2007-01-10 AU AU2007204226A patent/AU2007204226B2/en active Active
- 2007-01-10 EP EP07700357A patent/EP1984008B1/en active Active
-
2014
- 2014-06-05 US US14/297,500 patent/US9434933B2/en active Active
-
2016
- 2016-08-04 US US15/228,108 patent/US9670473B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2636633A1 (en) | 2007-07-19 |
| GB0600406D0 (en) | 2006-02-15 |
| CA2636633C (en) | 2019-02-05 |
| WO2007080400A3 (en) | 2007-11-08 |
| US9434933B2 (en) | 2016-09-06 |
| EP1984008B1 (en) | 2012-06-13 |
| US20100173977A1 (en) | 2010-07-08 |
| AU2007204226B2 (en) | 2012-08-02 |
| US20160333334A1 (en) | 2016-11-17 |
| WO2007080400A2 (en) | 2007-07-19 |
| AU2007204226A1 (en) | 2007-07-19 |
| ZA200806312B (en) | 2009-12-30 |
| US8796006B2 (en) | 2014-08-05 |
| EP1984008A2 (en) | 2008-10-29 |
| US20140377836A1 (en) | 2014-12-25 |
| US9670473B2 (en) | 2017-06-06 |
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